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MX2020000651A - Sistema de administracion transdermica con una membrana microporosa que tiene poros llenos de solvente. - Google Patents

Sistema de administracion transdermica con una membrana microporosa que tiene poros llenos de solvente.

Info

Publication number
MX2020000651A
MX2020000651A MX2020000651A MX2020000651A MX2020000651A MX 2020000651 A MX2020000651 A MX 2020000651A MX 2020000651 A MX2020000651 A MX 2020000651A MX 2020000651 A MX2020000651 A MX 2020000651A MX 2020000651 A MX2020000651 A MX 2020000651A
Authority
MX
Mexico
Prior art keywords
delivery system
transdermal delivery
microporous membrane
solvent
filled pores
Prior art date
Application number
MX2020000651A
Other languages
English (en)
Inventor
Eun Soo Lee
Amit K Jain
Parminder Singh
Original Assignee
Corium Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corium Inc filed Critical Corium Inc
Publication of MX2020000651A publication Critical patent/MX2020000651A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

Se describe un sistema de administración transdérmica, en donde el sistema comprende una capa de depósito de fármaco que comprende un agente activo y una capa adhesiva de contacto con la piel. Una membrana microporosa que ha sido tratada previamente con una composición de tratamiento de membrana antes de que la membrana se incorpore al sistema está dispuesta entre la capa de depósito de fármaco y la capa adhesiva de contacto con la piel.
MX2020000651A 2017-07-26 2018-07-26 Sistema de administracion transdermica con una membrana microporosa que tiene poros llenos de solvente. MX2020000651A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762537414P 2017-07-26 2017-07-26
PCT/US2018/043961 WO2019023499A1 (en) 2017-07-26 2018-07-26 TRANSDERMAL DELIVERY SYSTEM WITH MICROPOROUS MEMBRANE HAVING SOLVENT FILLED PORES

Publications (1)

Publication Number Publication Date
MX2020000651A true MX2020000651A (es) 2020-07-29

Family

ID=63165550

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020000651A MX2020000651A (es) 2017-07-26 2018-07-26 Sistema de administracion transdermica con una membrana microporosa que tiene poros llenos de solvente.

Country Status (10)

Country Link
US (2) US20190029971A1 (es)
EP (1) EP3658127A1 (es)
JP (2) JP2020529229A (es)
KR (1) KR102904873B1 (es)
CN (1) CN111132669A (es)
AU (1) AU2018307792B2 (es)
CA (1) CA3071007A1 (es)
MX (1) MX2020000651A (es)
SG (1) SG11202000415PA (es)
WO (1) WO2019023499A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2018008190A (es) 2015-12-30 2018-11-12 Corium Int Inc Sistemas y metodos para la administracion transdermica a largo plazo.
WO2017223402A1 (en) 2016-06-23 2017-12-28 Corium International, Inc. Adhesive matrix with hydrophilic and hydrophobic domains and a therapeutic agent
KR102555208B1 (ko) 2016-07-27 2023-07-17 코리움, 엘엘씨 아민 약물의 나트륨 바이카보네이트 제자리 전환 구동된 경피성 전달
WO2018022818A1 (en) 2016-07-27 2018-02-01 Corium International, Inc. Memantine transdermal delivery systems
JP2020529229A (ja) * 2017-07-26 2020-10-08 コリウム, インコーポレイテッド 溶媒充填細孔を有する微多孔膜を有する経皮送達システム
AU2018392686A1 (en) 2017-12-20 2020-07-09 Corium Pharma Solutions, Inc. Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point
US20230233480A1 (en) * 2019-10-24 2023-07-27 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system for the transdermal administration of fingolimod
US12390542B2 (en) * 2020-06-05 2025-08-19 Roxilla Llc On-demand agent dispensing devices and related methods
US20230072739A1 (en) 2021-06-28 2023-03-09 Corium, Llc Combination therapy treatment using transdermal delivery system
EP4362921A2 (en) 2021-06-28 2024-05-08 Corium, LLC Corona discharge treated transdermal delivery system
WO2024145319A1 (en) * 2022-12-28 2024-07-04 Corium, Llc Method of preparing transdermal delivery system
IL321722A (en) * 2022-12-28 2025-08-01 Corium Llc Premixing method for preparing a transdermal delivery system
WO2025103446A1 (zh) * 2023-11-16 2025-05-22 宜昌人福药业有限责任公司 含有多奈哌齐的透皮贴剂及其制备方法

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US4849224A (en) * 1987-11-12 1989-07-18 Theratech Inc. Device for administering an active agent to the skin or mucosa
JPH06199659A (ja) * 1992-10-28 1994-07-19 Hisamitsu Pharmaceut Co Inc 経皮治療用装置
US5635203A (en) * 1994-09-29 1997-06-03 Alza Corporation Transdermal device having decreased delamination
WO1996019205A1 (en) * 1994-12-21 1996-06-27 Theratech, Inc. Transdermal delivery system with adhesive overlay and peel seal disc
MXPA02000053A (es) * 1999-07-05 2003-07-21 Idea Ag Un metodo para mejorar el tratamiento a traves de barreras adaptables semipermeables.
US20020192243A1 (en) * 1999-12-16 2002-12-19 Tsung-Min Hsu Transdermal and topical administration of drugs for the treatment of Alzheimer's disease using basic enhancers
WO2002087645A1 (en) 2001-05-01 2002-11-07 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions
ATE399026T1 (de) 2003-11-21 2008-07-15 Memory Pharm Corp Zusammensetzungen enhaltend l-typ- calciumcanalblockern und cholinesterase-hemmern
AU2006343077B2 (en) * 2006-05-08 2012-11-08 Teikoku Seiyaku Co., Ltd. Tansdermally absorbable preparation comprising anti-dementia agent
US9248104B2 (en) * 2006-08-17 2016-02-02 Core Tech Solutions, Inc. Transdermal methods and systems for treating Alzheimer's disease
CN101605546B (zh) * 2006-12-01 2011-12-14 日东电工株式会社 抑制含有多奈哌齐的贴剂的经时变色的方法
DE102008013701A1 (de) * 2008-03-11 2009-09-17 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System mit stabilisierter Membran
KR101454362B1 (ko) * 2008-03-24 2014-10-23 아이큐어 주식회사 도네페질을 유효성분으로 함유하는 치매 치료용경피흡수제제
US20090291127A1 (en) * 2008-05-21 2009-11-26 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
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MX2018008190A (es) * 2015-12-30 2018-11-12 Corium Int Inc Sistemas y metodos para la administracion transdermica a largo plazo.
KR102555208B1 (ko) * 2016-07-27 2023-07-17 코리움, 엘엘씨 아민 약물의 나트륨 바이카보네이트 제자리 전환 구동된 경피성 전달
JP2020529229A (ja) 2017-07-26 2020-10-08 コリウム, インコーポレイテッド 溶媒充填細孔を有する微多孔膜を有する経皮送達システム

Also Published As

Publication number Publication date
US20240016759A1 (en) 2024-01-18
KR102904873B1 (ko) 2025-12-29
JP2023171749A (ja) 2023-12-05
CA3071007A1 (en) 2019-01-31
JP7611327B2 (ja) 2025-01-09
EP3658127A1 (en) 2020-06-03
KR20200032153A (ko) 2020-03-25
WO2019023499A1 (en) 2019-01-31
RU2020108005A3 (es) 2021-11-30
JP2020529229A (ja) 2020-10-08
CN111132669A (zh) 2020-05-08
AU2018307792B2 (en) 2024-08-08
AU2018307792A1 (en) 2020-02-06
SG11202000415PA (en) 2020-02-27
RU2020108005A (ru) 2021-08-26
US20190029971A1 (en) 2019-01-31

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