MX2019001096A - Antagonistas del receptor 7/8 tipo toll (tlr7/8) y uso de los mismos. - Google Patents
Antagonistas del receptor 7/8 tipo toll (tlr7/8) y uso de los mismos.Info
- Publication number
- MX2019001096A MX2019001096A MX2019001096A MX2019001096A MX2019001096A MX 2019001096 A MX2019001096 A MX 2019001096A MX 2019001096 A MX2019001096 A MX 2019001096A MX 2019001096 A MX2019001096 A MX 2019001096A MX 2019001096 A MX2019001096 A MX 2019001096A
- Authority
- MX
- Mexico
- Prior art keywords
- tlr7
- antagonists
- compounds
- useful
- formula
- Prior art date
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- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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- C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
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Abstract
La presente invención se relaciona con compuestos de la fórmula I y composiciones farmacéuticamente aceptables de los mismos, útiles como antagonistas de TLR7/8.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662371917P | 2016-08-08 | 2016-08-08 | |
| PCT/US2017/045671 WO2018031434A1 (en) | 2016-08-08 | 2017-08-07 | Tlr7/8 antagonists and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019001096A true MX2019001096A (es) | 2019-07-04 |
| MX390698B MX390698B (es) | 2025-03-11 |
Family
ID=59656207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| IL264676B (en) | 2022-04-01 |
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| KR20240019867A (ko) | 2024-02-14 |
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| JP2019527718A (ja) | 2019-10-03 |
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| EP3497094A1 (en) | 2019-06-19 |
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| US20180037570A1 (en) | 2018-02-08 |
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| EP3497094B1 (en) | 2023-02-15 |
| RU2758686C2 (ru) | 2021-11-01 |
| SG11201900947RA (en) | 2019-02-27 |
| JP7125385B2 (ja) | 2022-08-24 |
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