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MX2018000590A - Moleculas de anticuerpo que se unen a agrupacion de diferenciacion 79 (cd79). - Google Patents

Moleculas de anticuerpo que se unen a agrupacion de diferenciacion 79 (cd79).

Info

Publication number
MX2018000590A
MX2018000590A MX2018000590A MX2018000590A MX2018000590A MX 2018000590 A MX2018000590 A MX 2018000590A MX 2018000590 A MX2018000590 A MX 2018000590A MX 2018000590 A MX2018000590 A MX 2018000590A MX 2018000590 A MX2018000590 A MX 2018000590A
Authority
MX
Mexico
Prior art keywords
antibody molecules
bind
seq
binding domain
compositions
Prior art date
Application number
MX2018000590A
Other languages
English (en)
Inventor
Edward Rapecki Stephen
John Wright Michael
Margaret Finney Helene
Louise Tyson Kerry
Original Assignee
Ucb Biopharma Sprl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2015/066369 external-priority patent/WO2016009030A2/en
Priority claimed from PCT/EP2015/066368 external-priority patent/WO2016009029A1/en
Application filed by Ucb Biopharma Sprl filed Critical Ucb Biopharma Sprl
Publication of MX2018000590A publication Critical patent/MX2018000590A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
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Abstract

La presente descripción se refiere a moléculas de anticuerpo que comprenden un dominio de unión específico para CD79, comprendiendo el dominio de unión las SEQ ID NO: 1, 2, 3 o 4, y/o las SEQ ID NO: 5, 6 y 7. La descripción también se extiende a composiciones farmacéuticas que comprenden las moléculas de anticuerpo y al uso de las moléculas de anticuerpo/composiciones en tratamiento.
MX2018000590A 2015-07-16 2016-07-15 Moleculas de anticuerpo que se unen a agrupacion de diferenciacion 79 (cd79). MX2018000590A (es)

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PCT/EP2015/066369 WO2016009030A2 (en) 2014-07-16 2015-07-16 Molecules with specificity for cd79 and cd22
PCT/EP2015/066368 WO2016009029A1 (en) 2014-07-16 2015-07-16 Molecules with specificity for cd45 and cd79
GBGB1601075.3A GB201601075D0 (en) 2016-01-20 2016-01-20 Antibodies molecules
PCT/EP2016/066989 WO2017009474A1 (en) 2015-07-16 2016-07-15 Antibody molecules which bind cd79

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