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MX2017012073A - Compuestos de minociclina para biodefensas. - Google Patents

Compuestos de minociclina para biodefensas.

Info

Publication number
MX2017012073A
MX2017012073A MX2017012073A MX2017012073A MX2017012073A MX 2017012073 A MX2017012073 A MX 2017012073A MX 2017012073 A MX2017012073 A MX 2017012073A MX 2017012073 A MX2017012073 A MX 2017012073A MX 2017012073 A MX2017012073 A MX 2017012073A
Authority
MX
Mexico
Prior art keywords
bacterial infection
biodefense
minocycline compounds
bacterium
treating
Prior art date
Application number
MX2017012073A
Other languages
English (en)
Other versions
MX389771B (es
Inventor
P Draper Michael
Ken Tanaka S
Original Assignee
Paratek Pharm Innc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paratek Pharm Innc filed Critical Paratek Pharm Innc
Publication of MX2017012073A publication Critical patent/MX2017012073A/es
Publication of MX389771B publication Critical patent/MX389771B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

En el presente documento se dan a conocer procedimientos para tratar o prevenir una infección bacteriana en un individuo, en donde la infección bacteriana es causada por una bacteria que puede usarse como arma biológica. También se describe una composición farmacéutica que comprende el compuesto de la presente invención para tratar o prevenir una infección bacteriana en un individuo, en donde la infección bacteriana es causada por una bacteria que puede usarse como arma biológica.
MX2017012073A 2015-03-24 2016-03-23 Compuestos de minociclina para biodefensas. MX389771B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562137719P 2015-03-24 2015-03-24
PCT/US2016/023807 WO2016154332A1 (en) 2015-03-24 2016-03-23 Minocycline compounds for biodefense

Publications (2)

Publication Number Publication Date
MX2017012073A true MX2017012073A (es) 2018-02-21
MX389771B MX389771B (es) 2025-03-20

Family

ID=56977663

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017012073A MX389771B (es) 2015-03-24 2016-03-23 Compuestos de minociclina para biodefensas.

Country Status (14)

Country Link
US (5) US20180133231A1 (es)
EP (2) EP3273968B1 (es)
JP (4) JP6826582B2 (es)
KR (3) KR102656263B1 (es)
CN (2) CN116392496A (es)
AU (4) AU2016235151A1 (es)
CA (1) CA2980727C (es)
ES (1) ES2959665T3 (es)
FI (1) FI3273968T3 (es)
HU (1) HUE063795T2 (es)
IL (1) IL254622B2 (es)
MX (1) MX389771B (es)
PL (1) PL3273968T3 (es)
WO (1) WO2016154332A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016235151A1 (en) * 2015-03-24 2017-10-12 Paratek Pharmaceuticals, Inc. Minocycline compounds for biodefense
CN109154685B (zh) * 2016-03-31 2022-04-19 日产化学株式会社 配向层形成组合物
TWI746610B (zh) * 2016-08-03 2021-11-21 美商派瑞泰Ｓｐｖ２有限公司 9-胺甲基米諾四環素化合物及其用途
SG10201913599RA (en) 2016-11-01 2020-02-27 Paratek Pharm Innc 9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp)
MA52980A (fr) * 2018-04-30 2021-04-28 Melinta Therapeutics Inc Procédés de traitement d'infections bactériennes à l'aide d'oritavancine
PT3917616T (pt) 2019-01-31 2025-08-28 Takeda Pharmaceuticals Co Compostos heterocíclicos e a sua utilização
CN111484424B (zh) * 2020-04-14 2022-10-25 成都百特万合医药科技有限公司 一种合成奥马环素的方法
PT117254B (pt) 2021-05-26 2024-04-18 Hovione Farm S A Método de síntese de compostos 9-aminometil tetraciclinas
CN114591216A (zh) * 2022-02-17 2022-06-07 四川澄华生物科技有限公司 一种合成奥马环素中间体的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8638801A (en) 2000-07-07 2002-01-21 Tufts College 9-substituted minocycline compounds
WO2011101710A1 (en) * 2010-02-16 2011-08-25 Wockhardt Research Centre Efflux pump inhibitors
US7553828B2 (en) 2001-03-13 2009-06-30 Paratek Pharmaceuticals, Inc. 9-aminomethyl substituted minocycline compounds
CA2475202A1 (en) * 2002-03-29 2003-10-09 The Research Foundation Of State University Of New York Use of non-antibacterial tetracycline analogs and formulations thereof for the treatment of bacterial exotoxins
US7943600B2 (en) 2004-12-20 2011-05-17 Massachusetts Institute Of Technology Antimicrobial combination therapy
US20070238652A1 (en) * 2006-02-08 2007-10-11 Biosynexus Incorporated Neutralization of bacterial spores
US8440646B1 (en) 2006-10-11 2013-05-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of Bacillus anthracis infections
EP2216323A3 (en) 2007-04-27 2010-12-29 Paratek Pharmaceuticals, Inc. Methods for synthesizing and purifying aminoalkyl tetracycline compounds
BRPI0908951A2 (pt) * 2008-03-05 2017-01-17 Paratek Pharm Innc compostos de minociclina e método de uso dos mesmos
EP2849757A4 (en) * 2012-05-14 2015-11-18 Paratek Pharm Innc PROCESS FOR USE OF (4S, 4AS, 5AR, 12AS -) - 4-DIMETHYLAMINO-3,10,12,12A-TETRAHYDROXY-7 - [(METHOXY (METHYL) AMINO) -METHYL] -1,11-DIOXO-1 , 4.4A, 5.5A, 6,11,12a-octahydro-naphthacene-2-carboxylic acid amide
AU2016235151A1 (en) * 2015-03-24 2017-10-12 Paratek Pharmaceuticals, Inc. Minocycline compounds for biodefense

Also Published As

Publication number Publication date
PL3273968T3 (pl) 2024-01-03
US20250367219A1 (en) 2025-12-04
US11129839B2 (en) 2021-09-28
KR20170138439A (ko) 2017-12-15
KR20240051297A (ko) 2024-04-19
JP2021059544A (ja) 2021-04-15
KR20250151591A (ko) 2025-10-21
IL254622B2 (en) 2024-01-01
IL254622A0 (en) 2017-11-30
AU2020260450A1 (en) 2020-12-03
CA2980727C (en) 2023-09-19
AU2024202788A1 (en) 2024-05-23
MX389771B (es) 2025-03-20
US20240238315A1 (en) 2024-07-18
EP3273968B1 (en) 2023-07-19
JP2025023946A (ja) 2025-02-19
JP2023022179A (ja) 2023-02-14
AU2020260450B2 (en) 2022-07-21
EP3273968A1 (en) 2018-01-31
ES2959665T3 (es) 2024-02-27
JP6826582B2 (ja) 2021-02-03
EP3273968A4 (en) 2018-11-14
IL254622B1 (en) 2023-09-01
US20230098554A1 (en) 2023-03-30
AU2022256106A1 (en) 2022-11-24
WO2016154332A1 (en) 2016-09-29
KR102656263B1 (ko) 2024-04-09
CN116392496A (zh) 2023-07-07
HUE063795T2 (hu) 2024-01-28
JP2018509475A (ja) 2018-04-05
US20180133231A1 (en) 2018-05-17
FI3273968T3 (fi) 2023-10-09
US20200330489A1 (en) 2020-10-22
AU2016235151A1 (en) 2017-10-12
EP4268897A2 (en) 2023-11-01
CA2980727A1 (en) 2016-09-29
EP4268897A3 (en) 2024-01-03
CN107613988A (zh) 2018-01-19

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