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MX2017011129A - Derivado de amina ciclica y uso farmaceutico del mismo. - Google Patents

Derivado de amina ciclica y uso farmaceutico del mismo.

Info

Publication number
MX2017011129A
MX2017011129A MX2017011129A MX2017011129A MX2017011129A MX 2017011129 A MX2017011129 A MX 2017011129A MX 2017011129 A MX2017011129 A MX 2017011129A MX 2017011129 A MX2017011129 A MX 2017011129A MX 2017011129 A MX2017011129 A MX 2017011129A
Authority
MX
Mexico
Prior art keywords
amine derivative
cyclic amine
medical purposes
present
pain
Prior art date
Application number
MX2017011129A
Other languages
English (en)
Inventor
Morita Yasuhiro
Izumimoto Naoki
Iseki Katsuhiko
Iwano Shunsuke
Udagawa Shuji
Miyoshi Tomoya
Osada Yuji
Koreeda Tetsuro
Murakami Masanori
Shiraki Motohiro
Takahashi Kei
Oshida Keiyu
HIGASHI Eriko
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of MX2017011129A publication Critical patent/MX2017011129A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a un compuesto que ejerce un fuerte efecto analgésico contra el dolor, en particular, dolor neuropático y/o síndrome de fibromialgia. La presente invención proporciona un derivado de amina cíclica representado por la siguiente fórmula general o una sal del mismo farmacológicamente aceptable. (ver Fórmula).
MX2017011129A 2015-03-24 2016-03-24 Derivado de amina ciclica y uso farmaceutico del mismo. MX2017011129A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015061248 2015-03-24
PCT/JP2016/059298 WO2016152955A1 (ja) 2015-03-24 2016-03-24 環状アミン誘導体及びその医薬用途

Publications (1)

Publication Number Publication Date
MX2017011129A true MX2017011129A (es) 2017-11-28

Family

ID=56977478

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017011129A MX2017011129A (es) 2015-03-24 2016-03-24 Derivado de amina ciclica y uso farmaceutico del mismo.

Country Status (9)

Country Link
US (1) US10117853B2 (es)
EP (1) EP3275879B1 (es)
JP (1) JP6642422B2 (es)
CN (1) CN107207462B (es)
BR (1) BR112017020118B1 (es)
CA (1) CA2980259C (es)
ES (1) ES2770924T3 (es)
MX (1) MX2017011129A (es)
WO (1) WO2016152955A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10253014B2 (en) * 2015-03-24 2019-04-09 Toray Industries, Inc. Cyclic amine derivative and pharmaceutical use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2163150B (en) 1984-07-19 1988-05-25 Sandoz Ltd 3-aminopropoxyaryl derivatives
JP4563675B2 (ja) 2001-10-12 2010-10-13 ハイ・ポイント・ファーマスーティカルズ、エルエルシー 置換ピペリジン類、およびヒスタミンｈ３受容体関連疾患の治療のためのその使用
DE10211770A1 (de) * 2002-03-14 2003-10-02 Boehringer Ingelheim Pharma Neue substituierte Piperidine, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
JP2006008664A (ja) 2004-05-21 2006-01-12 Takeda Chem Ind Ltd イミダゾール誘導体、その製造法及び用途
WO2006137465A1 (ja) * 2005-06-24 2006-12-28 Shionogi & Co., Ltd. 含窒素複素環誘導体
WO2013147160A1 (ja) * 2012-03-29 2013-10-03 東レ株式会社 環状アミン誘導体及びその医薬用途
TWI652264B (zh) * 2013-09-26 2019-03-01 東麗股份有限公司 Cyclic amine derivatives and their medical uses
MX2017010624A (es) * 2015-02-27 2017-12-07 Toray Industries Derivado de amina ciclica y su uso farmaceutico.

Also Published As

Publication number Publication date
WO2016152955A1 (ja) 2016-09-29
CA2980259A1 (en) 2016-09-29
US10117853B2 (en) 2018-11-06
EP3275879A1 (en) 2018-01-31
CN107207462A (zh) 2017-09-26
CN107207462B (zh) 2020-03-06
US20180104221A1 (en) 2018-04-19
EP3275879B1 (en) 2020-01-15
EP3275879A4 (en) 2018-09-19
BR112017020118A2 (pt) 2018-05-29
CA2980259C (en) 2024-02-06
ES2770924T3 (es) 2020-07-03
BR112017020118B1 (pt) 2023-03-14
JPWO2016152955A1 (ja) 2018-01-11
JP6642422B2 (ja) 2020-02-05

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