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MX2017011120A - Derivado de amina ciclica y uso farmaceutico del mismo. - Google Patents

Derivado de amina ciclica y uso farmaceutico del mismo.

Info

Publication number
MX2017011120A
MX2017011120A MX2017011120A MX2017011120A MX2017011120A MX 2017011120 A MX2017011120 A MX 2017011120A MX 2017011120 A MX2017011120 A MX 2017011120A MX 2017011120 A MX2017011120 A MX 2017011120A MX 2017011120 A MX2017011120 A MX 2017011120A
Authority
MX
Mexico
Prior art keywords
amine derivative
cyclic amine
medical purposes
present
pain
Prior art date
Application number
MX2017011120A
Other languages
English (en)
Inventor
Morita Yasuhiro
Izumimoto Naoki
Iseki Katsuhiko
Iwano Shunsuke
Udagawa Shuji
Miyoshi Tomoya
Osada Yuji
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of MX2017011120A publication Critical patent/MX2017011120A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a un compuesto que ejerce un fuerte efecto analgésico contra el dolor, en particular, dolor neuropático. La presente invención proporciona un derivado de amina cíclica representado por la siguiente fórmula general o una sal del mismo farmacológicamente aceptable. (ver Fórmula).
MX2017011120A 2015-03-24 2016-03-24 Derivado de amina ciclica y uso farmaceutico del mismo. MX2017011120A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015061249 2015-03-24
PCT/JP2016/059293 WO2016152952A1 (ja) 2015-03-24 2016-03-24 環状アミン誘導体及びその医薬用途

Publications (1)

Publication Number Publication Date
MX2017011120A true MX2017011120A (es) 2017-11-28

Family

ID=56977381

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017011120A MX2017011120A (es) 2015-03-24 2016-03-24 Derivado de amina ciclica y uso farmaceutico del mismo.

Country Status (9)

Country Link
US (1) US10253014B2 (es)
EP (1) EP3275878B1 (es)
JP (1) JP6645425B2 (es)
CN (2) CN107250129A (es)
BR (1) BR112017020203A2 (es)
CA (1) CA2979326C (es)
ES (1) ES2794560T3 (es)
MX (1) MX2017011120A (es)
WO (1) WO2016152952A1 (es)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4563675B2 (ja) 2001-10-12 2010-10-13 ハイ・ポイント・ファーマスーティカルズ、エルエルシー 置換ピペリジン類、およびヒスタミンｈ３受容体関連疾患の治療のためのその使用
DE10211770A1 (de) * 2002-03-14 2003-10-02 Boehringer Ingelheim Pharma Neue substituierte Piperidine, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
WO2006137465A1 (ja) 2005-06-24 2006-12-28 Shionogi & Co., Ltd. 含窒素複素環誘導体
WO2013147160A1 (ja) * 2012-03-29 2013-10-03 東レ株式会社 環状アミン誘導体及びその医薬用途
TWI652264B (zh) * 2013-09-26 2019-03-01 東麗股份有限公司 Cyclic amine derivatives and their medical uses
MX2017010624A (es) * 2015-02-27 2017-12-07 Toray Industries Derivado de amina ciclica y su uso farmaceutico.
CN107207462B (zh) * 2015-03-24 2020-03-06 东丽株式会社 环状胺衍生物和其医药用途

Also Published As

Publication number Publication date
US20180072701A1 (en) 2018-03-15
JP6645425B2 (ja) 2020-02-14
CN115124512A (zh) 2022-09-30
US10253014B2 (en) 2019-04-09
EP3275878A4 (en) 2018-09-19
CA2979326C (en) 2023-05-16
WO2016152952A1 (ja) 2016-09-29
BR112017020203A2 (pt) 2018-06-05
CA2979326A1 (en) 2016-09-29
CN107250129A (zh) 2017-10-13
EP3275878A1 (en) 2018-01-31
EP3275878B1 (en) 2020-05-20
JPWO2016152952A1 (ja) 2018-01-11
ES2794560T3 (es) 2020-11-18

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Legal Events

Date Code Title Description
FG Grant or registration