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MX2017008380A - Compuestos, composiciones y metodos para incrementar la actividad del regulador de la conductancia transmembrana de la fibrosis quistica (cftr). - Google Patents

Compuestos, composiciones y metodos para incrementar la actividad del regulador de la conductancia transmembrana de la fibrosis quistica (cftr).

Info

Publication number
MX2017008380A
MX2017008380A MX2017008380A MX2017008380A MX2017008380A MX 2017008380 A MX2017008380 A MX 2017008380A MX 2017008380 A MX2017008380 A MX 2017008380A MX 2017008380 A MX2017008380 A MX 2017008380A MX 2017008380 A MX2017008380 A MX 2017008380A
Authority
MX
Mexico
Prior art keywords
cftr
activity
increase
compounds
chysical
Prior art date
Application number
MX2017008380A
Other languages
English (en)
Other versions
MX388421B (es
Inventor
Tait Bradley
M Bastos Cecilia
Munoz Benito
Original Assignee
Proteostasis Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proteostasis Therapeutics Inc filed Critical Proteostasis Therapeutics Inc
Publication of MX2017008380A publication Critical patent/MX2017008380A/es
Publication of MX388421B publication Critical patent/MX388421B/es

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Abstract

La presente descripción se refiere a compuestos descritos que aumentan la actividad del regulador de conductancia transmembrana de la fibrosis quística (CFTR) tal como se mide en células epiteliales bronquiales humanas (hBE).
MX2017008380A 2014-12-23 2015-12-23 Compuestos, composiciones y metodos para incrementar la actividad del regulador de la conductancia transmembrana de la fibrosis quistica (cftr). MX388421B (es)

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US201462096374P 2014-12-23 2014-12-23
US201562102244P 2015-01-12 2015-01-12
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US201562199661P 2015-07-31 2015-07-31
PCT/US2015/000212 WO2016105485A2 (en) 2014-12-23 2015-12-23 Compounds, compositions, and methods for increasing cftr activity

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BR112017013710B1 (pt) 2023-11-07
EP3237411A2 (en) 2017-11-01
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CA2971858A1 (en) 2016-06-30
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US11098035B2 (en) 2021-08-24
IL252987A0 (en) 2017-08-31
EP3237411B1 (en) 2023-06-07
RU2017126232A3 (es) 2019-06-17
KR102677444B1 (ko) 2024-06-20
IL252987B (en) 2020-08-31
ES2962673T3 (es) 2024-03-20
NZ732701A (en) 2022-12-23
KR20170096034A (ko) 2017-08-23
CN107207487A (zh) 2017-09-26
AU2020256305A1 (en) 2020-11-12
SG11201704859UA (en) 2017-07-28
BR112017013710A2 (pt) 2018-01-02
US10392372B2 (en) 2019-08-27
WO2016105485A2 (en) 2016-06-30
MA41253A (fr) 2017-10-31
MX388421B (es) 2025-03-19
AU2022228100A1 (en) 2022-09-29
SA517381828B1 (ar) 2022-09-07
IL276426A (en) 2020-09-30
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US20170369480A1 (en) 2017-12-28
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AU2015371294B2 (en) 2020-07-16
RU2767460C2 (ru) 2022-03-17
US20200190072A1 (en) 2020-06-18
AU2015371294A1 (en) 2017-06-29

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