MX2016008667A - Inmunoglobulina con fab en tandem y usos de esta. - Google Patents
Inmunoglobulina con fab en tandem y usos de esta.Info
- Publication number
- MX2016008667A MX2016008667A MX2016008667A MX2016008667A MX2016008667A MX 2016008667 A MX2016008667 A MX 2016008667A MX 2016008667 A MX2016008667 A MX 2016008667A MX 2016008667 A MX2016008667 A MX 2016008667A MX 2016008667 A MX2016008667 A MX 2016008667A
- Authority
- MX
- Mexico
- Prior art keywords
- fabs
- binding proteins
- tandem immunoglobulin
- multivalent
- present
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/244—Interleukins [IL]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
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- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
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- C07—ORGANIC CHEMISTRY
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- C07K2317/66—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a swap of domains, e.g. CH3-CH2, VH-CL or VL-CH1
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
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- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
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Abstract
La presente invención proporciona proteínas de unión multivalentes y multiespecíficas que son capaces de unirse a dos o más antígenos, o dos o más epítopos; la presente invención también proporciona métodos de elaboración y uso de esas proteínas de unión multivalentes y multiespecíficas, que incluyen métodos de uso de esas proteínas de unión para la prevención o el tratamiento de diversas enfermedades o para la detección de antígenos específicos in vitro o in vivo.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013090923 | 2013-12-30 | ||
| PCT/US2014/072336 WO2015103072A1 (en) | 2013-12-30 | 2014-12-24 | Fabs-in-tandem immunoglobulin and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2016008667A true MX2016008667A (es) | 2017-02-02 |
Family
ID=53493933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016008667A MX2016008667A (es) | 2013-12-30 | 2014-12-24 | Inmunoglobulina con fab en tandem y usos de esta. |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US10519251B2 (es) |
| EP (2) | EP3089994B1 (es) |
| JP (2) | JP6706578B2 (es) |
| KR (1) | KR102056963B1 (es) |
| CN (1) | CN106459182B (es) |
| AR (1) | AR098979A1 (es) |
| AU (1) | AU2014374055B2 (es) |
| BR (1) | BR112016015140A2 (es) |
| CA (1) | CA2931641C (es) |
| CU (1) | CU20160101A7 (es) |
| DK (1) | DK3089994T3 (es) |
| ES (1) | ES2923641T3 (es) |
| IL (1) | IL246287B (es) |
| MX (1) | MX2016008667A (es) |
| NZ (1) | NZ720353A (es) |
| RU (2) | RU2016129959A (es) |
| TW (1) | TWI672316B (es) |
| WO (1) | WO2015103072A1 (es) |
Families Citing this family (257)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| RU2767329C2 (ru) * | 2016-02-06 | 2022-03-17 | Эпимаб Биотерапьютикс, Инк. | Иммуноглобулин с тандемными fab-фрагментами и варианты его применения |
| AU2019263850A1 (en) * | 2018-05-03 | 2020-11-19 | Shanghai Epimab Biotherapeutics Co., Ltd. | High affinity antibodies to PD-1 and LAG-3 and bispecific binding proteins made therefrom |
| EP3820895A4 (en) * | 2018-07-09 | 2022-04-27 | Shanghai Epimab Biotherapeutics Co., Ltd. | EFFICIENTLY EXPRESSED EGFR AND PD-L1 BINDER PROTEINS |
| CN114728065A (zh) * | 2019-11-26 | 2022-07-08 | 上海岸迈生物科技有限公司 | 针对cd3和bcma的抗体和自其制备的双特异性结合蛋白 |
| AU2021334677A1 (en) * | 2020-08-24 | 2023-03-02 | Epimab Biotherapeutics (Hk) Limited | Anti-ROR1 antibodies and related bispecific binding proteins |
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2014
- 2014-12-24 AU AU2014374055A patent/AU2014374055B2/en active Active
- 2014-12-24 BR BR112016015140-2A patent/BR112016015140A2/pt not_active Application Discontinuation
- 2014-12-24 MX MX2016008667A patent/MX2016008667A/es unknown
- 2014-12-24 ES ES14877308T patent/ES2923641T3/es active Active
- 2014-12-24 WO PCT/US2014/072336 patent/WO2015103072A1/en not_active Ceased
- 2014-12-24 RU RU2016129959A patent/RU2016129959A/ru unknown
- 2014-12-24 NZ NZ720353A patent/NZ720353A/en unknown
- 2014-12-24 KR KR1020167020580A patent/KR102056963B1/ko active Active
- 2014-12-24 JP JP2016544523A patent/JP6706578B2/ja active Active
- 2014-12-24 EP EP14877308.8A patent/EP3089994B1/en active Active
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- 2014-12-24 CA CA2931641A patent/CA2931641C/en active Active
- 2014-12-24 RU RU2020142965A patent/RU2769133C2/ru active
- 2014-12-24 DK DK14877308.8T patent/DK3089994T3/da active
- 2014-12-24 US US14/732,088 patent/US10519251B2/en active Active
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- 2016-05-04 US US15/146,540 patent/US10266608B2/en active Active
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2019
- 2019-04-22 US US16/390,912 patent/US20230132403A9/en active Pending
- 2019-12-19 US US16/720,422 patent/US20200157249A1/en not_active Abandoned
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2020
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