MX2015010043A - Métodos para mejorar la produccion de rebaudiosido d y rebaudiosido m. - Google Patents
Métodos para mejorar la produccion de rebaudiosido d y rebaudiosido m.Info
- Publication number
- MX2015010043A MX2015010043A MX2015010043A MX2015010043A MX2015010043A MX 2015010043 A MX2015010043 A MX 2015010043A MX 2015010043 A MX2015010043 A MX 2015010043A MX 2015010043 A MX2015010043 A MX 2015010043A MX 2015010043 A MX2015010043 A MX 2015010043A
- Authority
- MX
- Mexico
- Prior art keywords
- rebaudioside
- methods
- improved production
- compositions containing
- provides methods
- Prior art date
Links
- RPYRMTHVSUWHSV-CUZJHZIBSA-N rebaudioside D Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O RPYRMTHVSUWHSV-CUZJHZIBSA-N 0.000 title 2
- GSGVXNMGMKBGQU-PHESRWQRSA-N rebaudioside M Chemical compound C[C@@]12CCC[C@](C)([C@H]1CC[C@@]13CC(=C)[C@@](C1)(CC[C@@H]23)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O GSGVXNMGMKBGQU-PHESRWQRSA-N 0.000 title 1
- 239000004383 Steviol glycoside Substances 0.000 abstract 2
- 229930182488 steviol glycoside Natural products 0.000 abstract 2
- 235000019411 steviol glycoside Nutrition 0.000 abstract 2
- 150000008144 steviol glycosides Chemical class 0.000 abstract 2
- 235000019202 steviosides Nutrition 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/33—Artificial sweetening agents containing sugars or derivatives
- A23L27/36—Terpene glycosides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Seasonings (AREA)
- Enzymes And Modification Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Non-Alcoholic Beverages (AREA)
- Peptides Or Proteins (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
La presente invención proporciona métodos para la producción recombinante de glicósido de esteviol y composiciones que contienen glicósidos de esteviol.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361761490P | 2013-02-06 | 2013-02-06 | |
| US201361886442P | 2013-10-03 | 2013-10-03 | |
| PCT/EP2014/052363 WO2014122227A2 (en) | 2013-02-06 | 2014-02-06 | Methods for improved production of rebaudioside d and rebaudioside m |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015010043A true MX2015010043A (es) | 2016-03-04 |
| MX369525B MX369525B (es) | 2019-11-11 |
Family
ID=50064631
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015010043A MX369525B (es) | 2013-02-06 | 2014-02-06 | Métodos para mejorar la produccion de rebaudiosido d y rebaudiosido m. |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US9957540B2 (es) |
| EP (2) | EP3892728A1 (es) |
| JP (4) | JP6379112B2 (es) |
| KR (1) | KR20150115002A (es) |
| CN (2) | CN110551646B (es) |
| AU (4) | AU2014214004B2 (es) |
| CA (2) | CA2899276C (es) |
| MX (1) | MX369525B (es) |
| MY (2) | MY190346A (es) |
| SG (2) | SG11201505597SA (es) |
| WO (1) | WO2014122227A2 (es) |
Families Citing this family (110)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9107436B2 (en) | 2011-02-17 | 2015-08-18 | Purecircle Sdn Bhd | Glucosylated steviol glycoside as a flavor modifier |
| WO2016049315A1 (en) | 2014-09-26 | 2016-03-31 | Purecircle Usa Inc. | Stevia composition, production method and uses |
| US10696706B2 (en) | 2010-03-12 | 2020-06-30 | Purecircle Usa Inc. | Methods of preparing steviol glycosides and uses of the same |
| NZ604915A (en) | 2010-06-02 | 2014-10-31 | Evolva Nutrition Inc | Recombinant production of steviol glycosides |
| US11690391B2 (en) | 2011-02-17 | 2023-07-04 | Purecircle Sdn Bhd | Glucosylated steviol glycoside as a flavor modifier |
| US9771434B2 (en) | 2011-06-23 | 2017-09-26 | Purecircle Sdn Bhd | Products from stevia rebaudiana |
| CN103732753B (zh) | 2011-08-08 | 2018-03-30 | 埃沃尔瓦公司 | 甜菊醇糖苷类的重组生产 |
| EP2826861B1 (en) | 2012-03-16 | 2020-04-29 | Suntory Holdings Limited | Steviol glycosyltransferase and gene encoding same |
| ES2820518T3 (es) | 2012-03-27 | 2021-04-21 | Suntory Holdings Ltd | Método para producir glucósido de esteviol |
| CN110358795B (zh) * | 2012-05-22 | 2024-12-03 | 谱赛科有限责任公司 | 高纯度的甜菊醇糖苷 |
| US9752174B2 (en) | 2013-05-28 | 2017-09-05 | Purecircle Sdn Bhd | High-purity steviol glycosides |
| TW201402599A (zh) | 2012-05-30 | 2014-01-16 | Suntory Holdings Ltd | 甜菊糖苷糖苷轉化酵素及編碼該酵素之基因 |
| EP3892728A1 (en) * | 2013-02-06 | 2021-10-13 | Evolva SA | Methods for improved production of rebaudioside d and rebaudioside m |
| SG10201705993YA (en) | 2013-02-11 | 2017-08-30 | Evolva Sa | Efficient production of steviol glycosides in recombinant hosts |
| AU2014273055A1 (en) * | 2013-05-31 | 2015-12-17 | Dsm Ip Assets B.V. | Microorganisms for diterpene production |
| US10952458B2 (en) | 2013-06-07 | 2021-03-23 | Purecircle Usa Inc | Stevia extract containing selected steviol glycosides as flavor, salty and sweetness profile modifier |
| PL3714699T3 (pl) | 2013-06-07 | 2025-04-28 | Purecircle Usa Inc. | EKSTRAKT Z STEWII ZAWIERAJĄCY WYBRANE GLIKOZYDY STEWIOLOWE JAKO MODYFIKATOR PROFILU SMAKOWEGO, SŁONEGO i SŁODKIEGO |
| CN108064135A (zh) * | 2013-07-15 | 2018-05-22 | 帝斯曼知识产权资产管理有限公司 | 二萜的生产 |
| BR112016002092B1 (pt) * | 2013-07-31 | 2020-12-15 | Dsm Ip Assets B.V. | Recuperação de glicosídeos de esteviol |
| CN103397064B (zh) * | 2013-08-14 | 2015-04-15 | 苏州汉酶生物技术有限公司 | 一种酶法制备瑞鲍迪甙m的方法 |
| US9522929B2 (en) | 2014-05-05 | 2016-12-20 | Conagen Inc. | Non-caloric sweetener |
| MX2017001859A (es) | 2014-08-11 | 2017-04-11 | Evolva Sa | Produccion de glicosidos de esteviol en hospederos recombinantes. |
| WO2016028899A1 (en) * | 2014-08-19 | 2016-02-25 | The Coca-Cola Company | Methods for preparing rebaudioside i and uses |
| BR112017004238A2 (pt) | 2014-09-02 | 2017-12-12 | Purecircle Usa Inc | extratos de estévia enriquecidos em rebaudiosídeo d, e, n e/ou o e processo para a preparação dos mesmos |
| KR20170052647A (ko) | 2014-09-09 | 2017-05-12 | 에볼바 에스아 | 재조합 숙주에서 스테비올 글리코시드의 생성 |
| EP3193636B1 (en) * | 2014-09-19 | 2022-07-06 | PureCircle SDN BHD | High-purity steviol glycosides |
| CN106714578B (zh) * | 2014-10-03 | 2020-07-28 | 康纳根有限公司 | 无热量甜味剂及合成方法 |
| EP3215629B1 (en) * | 2014-11-05 | 2024-08-07 | Manus Bio Inc. | Microbial production of steviol glycosides |
| WO2016100689A1 (en) * | 2014-12-17 | 2016-06-23 | Cargill, Incorporated | Steviol glycoside compounds, compositions for oral ingestion or use, and method for enhancing steviol glycoside solubility |
| JP2018503388A (ja) | 2015-01-30 | 2018-02-08 | エヴォルヴァ エスアー.Evolva Sa. | 組み換え宿主におけるステビオールグリコシドの生産 |
| BR112017017207B1 (pt) * | 2015-02-10 | 2022-10-18 | Purecircle Usa Inc. | Processo para produzir um glicosídeo terpenoide, composição de sabor, ingrediente alimentício, alimento, bebida ou outro produto consumível, cosmético e produto farmacêutico que compreende o dito glicosídeo terpenoide |
| WO2016144175A1 (en) | 2015-03-10 | 2016-09-15 | Rijksuniversiteit Groningen | Methods for the enzymatic modification of steviol glycosides, modified steviol glycosides obtainable thereby, and the use thereof as sweeteners |
| US10604743B2 (en) | 2015-03-16 | 2020-03-31 | Dsm Ip Assets B.V. | UDP-glycosyltransferases |
| BR112017021066B1 (pt) | 2015-04-03 | 2022-02-08 | Dsm Ip Assets B.V. | Glicosídeos de esteviol, método para a produção de um glicosídeo de esteviol, composição, usos relacionados, gênero alimentício, alimento para animais e bebida |
| US10752928B2 (en) | 2015-04-14 | 2020-08-25 | Conagen Inc. | Production of non-caloric sweeteners using engineered whole-cell catalysts |
| US20180132515A1 (en) * | 2015-04-21 | 2018-05-17 | Dsm Ip Assets B.V. | Geranylgeranyl pyrophosphate synthase |
| WO2016187559A1 (en) * | 2015-05-20 | 2016-11-24 | Cargill, Incorporated | Glycoside compositions |
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| EP4063513A1 (en) | 2015-05-29 | 2022-09-28 | Cargill, Incorporated | Heat treatment to produce glycosides |
| AU2016301190A1 (en) * | 2015-08-06 | 2018-02-15 | Cargill, Incorporated | Fermentation methods for producing steviol glycosides |
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| JP6972123B2 (ja) | 2016-10-21 | 2021-11-24 | ペプシコ・インク | 酵素法を使用するレバウディオサイドnを調製するための方法 |
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| CN110358795B (zh) * | 2012-05-22 | 2024-12-03 | 谱赛科有限责任公司 | 高纯度的甜菊醇糖苷 |
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| US20150342234A1 (en) * | 2012-12-05 | 2015-12-03 | Evolva Sa | Steviol Glycoside Compositions Sensory Properties |
| EP3892728A1 (en) | 2013-02-06 | 2021-10-13 | Evolva SA | Methods for improved production of rebaudioside d and rebaudioside m |
| SG10201705993YA (en) | 2013-02-11 | 2017-08-30 | Evolva Sa | Efficient production of steviol glycosides in recombinant hosts |
| AU2014273055A1 (en) | 2013-05-31 | 2015-12-17 | Dsm Ip Assets B.V. | Microorganisms for diterpene production |
| BR112015029601A2 (pt) | 2013-05-31 | 2017-09-26 | Dsm Ip Assets Bv | produção de diterpeno extracelular |
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| US10604743B2 (en) | 2015-03-16 | 2020-03-31 | Dsm Ip Assets B.V. | UDP-glycosyltransferases |
| AU2016301190A1 (en) * | 2015-08-06 | 2018-02-15 | Cargill, Incorporated | Fermentation methods for producing steviol glycosides |
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