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MX2014008705A - Compuestos tricíclicos de sulfona y métodos para elaborarlos y utilizarlos. - Google Patents

Compuestos tricíclicos de sulfona y métodos para elaborarlos y utilizarlos.

Info

Publication number
MX2014008705A
MX2014008705A MX2014008705A MX2014008705A MX2014008705A MX 2014008705 A MX2014008705 A MX 2014008705A MX 2014008705 A MX2014008705 A MX 2014008705A MX 2014008705 A MX2014008705 A MX 2014008705A MX 2014008705 A MX2014008705 A MX 2014008705A
Authority
MX
Mexico
Prior art keywords
methods
making
same
sulfone compounds
tricyclic
Prior art date
Application number
MX2014008705A
Other languages
English (en)
Inventor
Robert Zahler
Hazel Joan Dyke
Thomas David Pallin
Susan Mary Cramp
Original Assignee
Zafgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zafgen Inc filed Critical Zafgen Inc
Publication of MX2014008705A publication Critical patent/MX2014008705A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

La invención proporciona compuestos tricíclicos de sulfona y su uso en el tratamiento de trastornos médicos, tales como la obesidad; se proporcionan composiciones farmacéuticas y métodos para producir diversos compuestos tricíclicos; se contempla que los compuestos tengan actividad contra metionil aminopeptidasa 2.
MX2014008705A 2012-01-18 2013-01-17 Compuestos tricíclicos de sulfona y métodos para elaborarlos y utilizarlos. MX2014008705A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261587825P 2012-01-18 2012-01-18
PCT/US2013/021914 WO2013109735A1 (en) 2012-01-18 2013-01-17 Tricyclic sulfone compounds and methods of making and using same

Publications (1)

Publication Number Publication Date
MX2014008705A true MX2014008705A (es) 2015-02-05

Family

ID=47710307

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014008705A MX2014008705A (es) 2012-01-18 2013-01-17 Compuestos tricíclicos de sulfona y métodos para elaborarlos y utilizarlos.

Country Status (10)

Country Link
US (1) US9440943B2 (es)
EP (1) EP2804856B1 (es)
JP (1) JP2015509102A (es)
KR (1) KR20140112566A (es)
CN (1) CN104169268A (es)
AU (1) AU2013209719A1 (es)
BR (1) BR112014017780A8 (es)
CA (1) CA2861381A1 (es)
MX (1) MX2014008705A (es)
WO (1) WO2013109735A1 (es)

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US10174009B2 (en) 2012-11-05 2019-01-08 Zafgen, Inc. Tricyclic sulphonamide compounds and methods of making and using same
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MX362391B (es) 2013-03-14 2019-01-15 Zafgen Inc Métodos de tratamiento de enfermedad renal y otros trastornos.
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CN106432255A (zh) 2015-08-11 2017-02-22 扎夫根公司 烟曲霉素醇螺环化合物和制备和使用其的方法
BR112018014788B1 (pt) * 2016-03-22 2022-03-22 Helsinn Healthcare Sa Composto e uso de um composto
CN107056742A (zh) * 2017-04-20 2017-08-18 牛永友 一种治疗哮喘的药物组合物
CN112898202B (zh) * 2021-01-27 2022-11-22 中国科学院上海有机化学研究所 一种杂环基并环丙烷化合物、合成方法

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Also Published As

Publication number Publication date
KR20140112566A (ko) 2014-09-23
EP2804856A1 (en) 2014-11-26
BR112014017780A8 (pt) 2017-07-11
CA2861381A1 (en) 2013-07-25
AU2013209719A1 (en) 2014-08-07
US20150119456A1 (en) 2015-04-30
US9440943B2 (en) 2016-09-13
WO2013109735A1 (en) 2013-07-25
JP2015509102A (ja) 2015-03-26
BR112014017780A2 (es) 2017-06-20
EP2804856B1 (en) 2017-03-15
CN104169268A (zh) 2014-11-26

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