MX2013014142A - Composicion farmaceutica o nutraceutica de resistencia gastrica con resistencia contra la influenza de etanol. - Google Patents
Composicion farmaceutica o nutraceutica de resistencia gastrica con resistencia contra la influenza de etanol.Info
- Publication number
- MX2013014142A MX2013014142A MX2013014142A MX2013014142A MX2013014142A MX 2013014142 A MX2013014142 A MX 2013014142A MX 2013014142 A MX2013014142 A MX 2013014142A MX 2013014142 A MX2013014142 A MX 2013014142A MX 2013014142 A MX2013014142 A MX 2013014142A
- Authority
- MX
- Mexico
- Prior art keywords
- gastric resistant
- weight
- ethanol
- pharmaceutical
- influence
- Prior art date
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title abstract 4
- 230000002496 gastric effect Effects 0.000 title abstract 4
- 239000002417 nutraceutical Substances 0.000 title abstract 4
- 235000021436 nutraceutical agent Nutrition 0.000 title abstract 4
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 abstract 2
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 239000011247 coating layer Substances 0.000 abstract 2
- 229920001577 copolymer Polymers 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
- 125000002348 vinylic group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se relaciona con una composición farmacéutica o nutracéutica de resistencia gástrica, que comprende un centro, que contiene un ingrediente activo farmacéutico o nutracéutico y una capa de recubrimiento de resistencia gástrica en el centro, en donde la capa de recubrimiento de resistencia gástrica comprende por lo menos 30% en peso de un copolímero de (met)acrilato, que comprende unidades polimerizadas de 10 a 40% en peso de ácido acrílico o metacrílico, 10 a 80% en peso de un éster de alquilo C4 a C18 de ácido acrílico o metacrílico y, opcionalmente, 0 a 60% en peso de otro monómero vinílico, por lo que la liberación del ingrediente activo farmacéutico o nutracéutico no es mayor de 10% bajo condiciones in vitro, a pH 1.2 después de 2 horas en un medio de acuerdo con USP, con y sin la adición de etanol al 20% (v/v).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2011060098 | 2011-06-17 | ||
| PCT/EP2012/061051 WO2012171884A1 (en) | 2011-06-17 | 2012-06-12 | Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013014142A true MX2013014142A (es) | 2014-01-23 |
| MX356579B MX356579B (es) | 2018-06-05 |
Family
ID=46354217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013014142A MX356579B (es) | 2011-06-17 | 2012-06-12 | Composicion farmaceutica o nutraceutica de resistencia gastrica con resistencia contra la influenza de etanol. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9775815B2 (es) |
| JP (1) | JP6099638B2 (es) |
| KR (1) | KR101902602B1 (es) |
| CN (1) | CN103501768B (es) |
| AU (1) | AU2012269187A1 (es) |
| BR (1) | BR112013027484A8 (es) |
| CA (1) | CA2839525C (es) |
| ES (1) | ES2600853T3 (es) |
| HU (1) | HUE030548T2 (es) |
| IL (1) | IL228396A0 (es) |
| MX (1) | MX356579B (es) |
| RU (1) | RU2649806C2 (es) |
| WO (1) | WO2012171884A1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9775815B2 (en) | 2011-06-17 | 2017-10-03 | Evonik Roehm Gmbh | Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol |
| HUE049247T2 (hu) * | 2014-11-26 | 2020-09-28 | Evonik Operations Gmbh | Etanol hatásával szemben ellenálló gyógyászati vagy táplálék-gyógyszerészeti kompozíció |
| US20200289423A1 (en) | 2017-09-14 | 2020-09-17 | Evonik Operations Gmbh | Polymer and dosage form with sustained release properties and resistance against the influence of ethanol |
| MX2020009385A (es) * | 2018-03-09 | 2020-10-28 | Evonik Operations Gmbh | Mezcla de polimeros con resistencia a la influencia del etanol. |
| AU2019275409B2 (en) | 2018-05-24 | 2024-08-15 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
| WO2019222856A1 (en) | 2018-05-24 | 2019-11-28 | Nureva Inc. | Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones |
| JP2021524841A (ja) | 2018-05-24 | 2021-09-16 | セラニーズ・イーブイエイ・パフォーマンス・ポリマーズ・エルエルシー | 高分子薬剤化合物の持続放出用の埋め込み型デバイス |
| CN109232795A (zh) * | 2018-09-21 | 2019-01-18 | 佛山市森昂生物科技有限公司 | 一种防水型高韧性包衣材料的制备方法 |
| MX2021010914A (es) * | 2019-03-11 | 2021-10-01 | Evonik Operations Gmbh | Forma de dosificacion que comprende una matriz polimerica. |
| EP3981849A4 (en) * | 2019-06-07 | 2023-06-07 | Nippon Soda Co., Ltd. | Wet coating agent for fine particles |
| EP4329734A4 (en) | 2021-04-26 | 2025-04-02 | Celanese EVA Performance Polymers LLC | Implantable device for the delayed release of a macromolecular drug compound |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE9414065U1 (de) * | 1994-08-31 | 1994-11-03 | Röhm GmbH & Co. KG, 64293 Darmstadt | Thermoplastischer Kunststoff für darmsaftlösliche Arznei-Umhüllungen |
| DE9414066U1 (de) | 1994-08-31 | 1994-11-03 | Röhm GmbH & Co. KG, 64293 Darmstadt | Überzugs- und Bindemittel für Arzneiformen sowie damit hergestellte Arzneiform |
| DE10220470A1 (de) * | 2002-04-30 | 2003-11-20 | Roehm Gmbh | ph-sensitives Polymer |
| DE10011447A1 (de) | 2000-03-10 | 2001-09-20 | Roehm Gmbh | Dispersion mit nichtionischem Emulgator |
| JPWO2002032431A1 (ja) * | 2000-10-16 | 2004-02-26 | 久光製薬株式会社 | 外用剤組成物 |
| WO2003051340A1 (en) * | 2001-12-19 | 2003-06-26 | Astrazeneca Ab | New film coating |
| DE10208335A1 (de) | 2002-02-27 | 2003-09-04 | Roehm Gmbh | Arzneiform und Verfahren zu ihrer Herstellung |
| JP3727290B2 (ja) | 2002-07-22 | 2005-12-14 | 日本カラコン株式会社 | 腸溶性水系コーティング剤 |
| DE10250543A1 (de) | 2002-10-29 | 2004-05-19 | Röhm GmbH & Co. KG | Mehrschichtige Arzneiform |
| MXPA04010956A (es) | 2003-01-30 | 2005-01-25 | Roehm Gmbh | Forma de dosis farmaceutica y metodo para la produccion de la misma. |
| US8168228B2 (en) * | 2003-10-17 | 2012-05-01 | Sandoz Ag | Antibiotic clarithromycin micropellet compositions |
| JP2007518670A (ja) | 2003-12-15 | 2007-07-12 | カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ | 苦味のある薬物、及びｐＨ感受性ポリマーを含む風味マスクされた医薬組成物 |
| DE102004011349A1 (de) | 2004-03-05 | 2005-09-22 | Basf Ag | Wässrige Polymerdispersion auf Basis von Alkyl(meth)-acrylaten |
| US7446157B2 (en) * | 2004-12-07 | 2008-11-04 | Key Medical Technologies, Inc. | Nanohybrid polymers for ophthalmic applications |
| DE102005024614A1 (de) * | 2005-05-25 | 2006-11-30 | Röhm Gmbh | Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug |
| DE102006051020A1 (de) | 2006-10-26 | 2008-04-30 | Evonik Röhm Gmbh | Verwendung von (Meth)acrylat-Copolymeren in Retard-Arzneiformen zur Verringerung des Einflusses von Ethanol auf die Wirkstofffreisetzung |
| CN100465201C (zh) | 2007-04-25 | 2009-03-04 | 上海大学 | 用作药物肠溶包衣材料的水溶性丙烯酸系树脂乳液的制备方法 |
| JP5204846B2 (ja) | 2007-09-21 | 2013-06-05 | エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング | エタノールの影響に対して耐性を有する非オピオイド薬のｐＨ依存性制御放出医薬組成物 |
| SI2187876T1 (sl) * | 2007-09-21 | 2012-12-31 | Evonik Roehm Gmbh | Od pH odvisen opioidni farmacevtski sestavek z nadzorovanim sproščanjem z odpornostjo na vpliv etanola |
| BRPI0823128B8 (pt) | 2008-09-24 | 2022-07-05 | Evonik Roehm Gmbh | composição farmacêutica de liberação controlada dependente do ph para não opioides com resistência contra a influência de etanol, e processo para sua preparação |
| CN102164588B (zh) | 2008-09-24 | 2015-07-08 | 赢创罗姆有限公司 | 耐受乙醇影响的pH依赖性受控释放的药物组合物 |
| US20110311631A1 (en) | 2009-03-18 | 2011-12-22 | Evonik Röhm Gmbh | Controlled release pharmaceutical composition with resistance against the influence of ethanol employing a coating comprising a polymer mixture and excipients |
| PL2408436T3 (pl) | 2009-03-18 | 2017-08-31 | Evonik Röhm Gmbh | Kompozycja farmaceutyczna o kontrolowanym uwalnianiu z odpornością na wpływ etanolu, wykorzystująca powłokę zawierającą neutralne polimery winylowe i zaróbki |
| SI2720682T1 (sl) | 2011-06-17 | 2017-05-31 | Evonik Roehm Gmbh | Sestavek za oplaščenje primeren za farmacevtske ali nutracevtske dozirne oblike |
| MX353426B (es) | 2011-06-17 | 2018-01-12 | Evonik Roehm Gmbh | Composicion de recubrimiento apropiada para formas de dosificacion farmaceuticas o nutraceuticas. |
| US9775815B2 (en) | 2011-06-17 | 2017-10-03 | Evonik Roehm Gmbh | Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol |
-
2012
- 2012-06-12 US US14/114,752 patent/US9775815B2/en not_active Expired - Fee Related
- 2012-06-12 BR BR112013027484A patent/BR112013027484A8/pt not_active IP Right Cessation
- 2012-06-12 RU RU2014101230A patent/RU2649806C2/ru active
- 2012-06-12 CN CN201280021621.7A patent/CN103501768B/zh not_active Expired - Fee Related
- 2012-06-12 HU HUE12729452A patent/HUE030548T2/en unknown
- 2012-06-12 JP JP2014515149A patent/JP6099638B2/ja not_active Expired - Fee Related
- 2012-06-12 AU AU2012269187A patent/AU2012269187A1/en not_active Abandoned
- 2012-06-12 MX MX2013014142A patent/MX356579B/es active IP Right Grant
- 2012-06-12 KR KR1020137033075A patent/KR101902602B1/ko not_active Expired - Fee Related
- 2012-06-12 WO PCT/EP2012/061051 patent/WO2012171884A1/en not_active Ceased
- 2012-06-12 CA CA2839525A patent/CA2839525C/en active Active
- 2012-06-12 ES ES12729452.8T patent/ES2600853T3/es active Active
-
2013
- 2013-09-12 IL IL228396A patent/IL228396A0/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| RU2014101230A (ru) | 2015-07-27 |
| IL228396A0 (en) | 2016-10-31 |
| AU2012269187A1 (en) | 2013-09-26 |
| CA2839525A1 (en) | 2012-12-20 |
| US20140141092A1 (en) | 2014-05-22 |
| BR112013027484A2 (pt) | 2017-01-10 |
| JP6099638B2 (ja) | 2017-03-22 |
| KR20140045942A (ko) | 2014-04-17 |
| MX356579B (es) | 2018-06-05 |
| BR112013027484A8 (pt) | 2022-07-05 |
| CN103501768B (zh) | 2016-11-09 |
| US9775815B2 (en) | 2017-10-03 |
| JP2014517020A (ja) | 2014-07-17 |
| HUE030548T2 (en) | 2017-05-29 |
| KR101902602B1 (ko) | 2018-09-28 |
| ES2600853T3 (es) | 2017-02-13 |
| RU2649806C2 (ru) | 2018-04-04 |
| CN103501768A (zh) | 2014-01-08 |
| WO2012171884A1 (en) | 2012-12-20 |
| CA2839525C (en) | 2019-07-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |