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MX2012014386A - Formas cristalinas de inhibidores de cinasa. - Google Patents

Formas cristalinas de inhibidores de cinasa.

Info

Publication number
MX2012014386A
MX2012014386A MX2012014386A MX2012014386A MX2012014386A MX 2012014386 A MX2012014386 A MX 2012014386A MX 2012014386 A MX2012014386 A MX 2012014386A MX 2012014386 A MX2012014386 A MX 2012014386A MX 2012014386 A MX2012014386 A MX 2012014386A
Authority
MX
Mexico
Prior art keywords
crystalline forms
kinase inhibitors
thieno
pyrazol
pyridin
Prior art date
Application number
MX2012014386A
Other languages
English (en)
Inventor
Paul J Brackemeyer
Geoff G Z Zhang
Ahmad Y Sheikh
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of MX2012014386A publication Critical patent/MX2012014386A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Las sales de N-(4-{4-amino-7-[1-(2-hidroxietil)-1H-pirazol-4-il]ti eno[3, 2-c]piridin-3-iI}fenil)N'-(3-fluorofenil) urea y las formas cristalinas de la misma, son ingredientes farmacéuticos adecuados para composiciones farmacéuticas útiles en el tratamiento de una enfermedad, por ejemplo cáncer.
MX2012014386A 2010-06-09 2011-06-08 Formas cristalinas de inhibidores de cinasa. MX2012014386A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35317010P 2010-06-09 2010-06-09
PCT/US2011/039603 WO2011156473A1 (en) 2010-06-09 2011-06-08 Crystalline forms of kinase inhibitors

Publications (1)

Publication Number Publication Date
MX2012014386A true MX2012014386A (es) 2013-05-01

Family

ID=44454074

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012014386A MX2012014386A (es) 2010-06-09 2011-06-08 Formas cristalinas de inhibidores de cinasa.

Country Status (8)

Country Link
US (1) US8633317B2 (es)
EP (1) EP2580221B1 (es)
JP (1) JP5727599B2 (es)
CN (1) CN103003283A (es)
CA (1) CA2802042A1 (es)
ES (1) ES2559212T3 (es)
MX (1) MX2012014386A (es)
WO (1) WO2011156473A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201911668VA (en) * 2014-02-07 2020-01-30 Global Blood Therapeutics Inc Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
WO2015200635A1 (en) * 2014-06-25 2015-12-30 Abbvie Inc. N-(4-{4-AMINO-7-[1-(2-HYDROXYETHYL)-1H-PYRAZOL-4-yl]THIENO[3,2-c]PYRIDIN-3-YL}PHENYL)-N'-(3-FLUOROPHENYL)UREA DOCUSATE
CN106854197B (zh) * 2015-12-08 2020-09-01 浙江亚太药业股份有限公司 一种吡啶衍生物的多晶型及其制备方法、用途
JP7038675B2 (ja) 2016-03-11 2022-03-18 ステルス バイオセラピューティクス インコーポレイテッド 結晶塩形態
CN110914287A (zh) 2017-04-05 2020-03-24 隐形生物治疗公司 Boc-d-arg-dmt-lys-(boc)-phe-nh2的结晶盐形式
US10676506B2 (en) 2018-01-26 2020-06-09 Stealth Biotherapeutics Corp. Crystalline bis- and tris-hydrochloride salt of elamipretide
CA3178415A1 (en) * 2020-05-11 2021-11-18 Mark R. Bray Salt and crystal forms of 4-amino-5-(6-(4-methylpiperazin-1-yl)-1h-benzo[d]imidazol-2-yl)thieno[2,3-b]pyridin-6(7h)-one

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050020619A1 (en) * 2003-07-24 2005-01-27 Patrick Betschmann Thienopyridine kinase inhibitors
US20050026944A1 (en) * 2003-07-24 2005-02-03 Patrick Betschmann Thienopyridine and furopyridine kinase inhibitors
GB0402518D0 (en) * 2004-02-05 2004-03-10 Astrazeneca Ab Therapeutic agents
EP1968979A2 (en) * 2005-12-08 2008-09-17 Abbott Laboratories 9-membered heterobicyclic compounds as inhibitors of protein kinases
AR070539A1 (es) * 2008-03-05 2010-04-14 Methylgene Inc Inhibidores de la actividad de proteina tirosina quinasa
UY32291A (es) * 2008-12-05 2010-07-30 Abbott Lab Inhibidores de quinasa con perfiles de seguridad cyp mejorados

Also Published As

Publication number Publication date
EP2580221A1 (en) 2013-04-17
JP5727599B2 (ja) 2015-06-03
HK1182383A1 (zh) 2013-11-29
WO2011156473A1 (en) 2011-12-15
CN103003283A (zh) 2013-03-27
US20120203002A1 (en) 2012-08-09
ES2559212T3 (es) 2016-02-11
JP2013528222A (ja) 2013-07-08
US8633317B2 (en) 2014-01-21
EP2580221B1 (en) 2015-10-21
CA2802042A1 (en) 2011-12-15

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Legal Events

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