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MX2012002365A - Generación de lineas de linfocitos t citotóxicos con especificidad contra antígenos tumorales multiples o virus múltiples. - Google Patents

Generación de lineas de linfocitos t citotóxicos con especificidad contra antígenos tumorales multiples o virus múltiples.

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Publication number
MX2012002365A
MX2012002365A MX2012002365A MX2012002365A MX2012002365A MX 2012002365 A MX2012002365 A MX 2012002365A MX 2012002365 A MX2012002365 A MX 2012002365A MX 2012002365 A MX2012002365 A MX 2012002365A MX 2012002365 A MX2012002365 A MX 2012002365A
Authority
MX
Mexico
Prior art keywords
generation
tumor antigens
viruses
ctl lines
specificity against
Prior art date
Application number
MX2012002365A
Other languages
English (en)
Inventor
Ann Marie Leen
Cliona Rooney
Ulrike Gerdemann
Juan Vera
Original Assignee
Baylor College Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor College Medicine filed Critical Baylor College Medicine
Publication of MX2012002365A publication Critical patent/MX2012002365A/es

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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Abstract

La invención abarca métodos y composiciones para la generación y el uso de linfocitos T citotóxicos que como objetivos selecciona múltiples virus o que son específicos para múltiples antígenos de tumores; en modalidades específicas, los métodos de generación hacen uso de ciertas citocinas para promover la proliferación y reducir la muerte celular en una población activada de células T y/o que emplean un biorreactor particular que tiene una membrana permeables a gases.
MX2012002365A 2009-08-24 2010-08-24 Generación de lineas de linfocitos t citotóxicos con especificidad contra antígenos tumorales multiples o virus múltiples. MX2012002365A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23626109P 2009-08-24 2009-08-24
PCT/US2010/046505 WO2011028531A1 (en) 2009-08-24 2010-08-24 Generation of ctl lines with specificity against multiple tumor antigens or multiple viruses

Publications (1)

Publication Number Publication Date
MX2012002365A true MX2012002365A (es) 2012-07-17

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MX2012002365A MX2012002365A (es) 2009-08-24 2010-08-24 Generación de lineas de linfocitos t citotóxicos con especificidad contra antígenos tumorales multiples o virus múltiples.

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Country Link
US (8) US9963677B2 (es)
EP (3) EP3101122B1 (es)
JP (1) JP2013502235A (es)
KR (1) KR20120059581A (es)
CN (1) CN102625832A (es)
AU (1) AU2010289785A1 (es)
CA (1) CA2772076A1 (es)
DK (1) DK2470644T3 (es)
ES (1) ES2953434T3 (es)
MX (1) MX2012002365A (es)
RU (1) RU2012111349A (es)
SG (1) SG178885A1 (es)
WO (1) WO2011028531A1 (es)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG178885A1 (en) 2009-08-24 2012-04-27 Baylor College Medicine Generation of ctl lines with specificity against multiple tumor antigens or multiple viruses
US8956860B2 (en) 2009-12-08 2015-02-17 Juan F. Vera Methods of cell culture for adoptive cell therapy
EP2611905A4 (en) * 2010-09-01 2014-02-12 Baylor College Medicine EBV-SPECIFIC CYTOTOXIC T-LYMPHOCYTES FOR THE TREATMENT OF LOCOREGIONAL NANOPHARYNX CARCINOMA (NPC)
AU2012258603A1 (en) 2011-05-26 2014-01-16 Geneius Biotechnology, Inc. Modulated immunodominance therapy
GB201121308D0 (en) * 2011-12-12 2012-01-25 Cell Medica Ltd Process
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WO2023159088A1 (en) 2022-02-15 2023-08-24 Marker Therapeutics, Inc. Compositions and methods for antigen-specific t cell expansion

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