MX2012001059A - Procesos relacionados con la alquilacion de pirazoles. - Google Patents
Procesos relacionados con la alquilacion de pirazoles.Info
- Publication number
- MX2012001059A MX2012001059A MX2012001059A MX2012001059A MX2012001059A MX 2012001059 A MX2012001059 A MX 2012001059A MX 2012001059 A MX2012001059 A MX 2012001059A MX 2012001059 A MX2012001059 A MX 2012001059A MX 2012001059 A MX2012001059 A MX 2012001059A
- Authority
- MX
- Mexico
- Prior art keywords
- sup
- optionally substituted
- pyrazoles
- alkylation
- compound
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000029936 alkylation Effects 0.000 title 1
- 238000005804 alkylation reaction Methods 0.000 title 1
- 150000003217 pyrazoles Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 2
- 125000003107 substituted aryl group Chemical group 0.000 abstract 2
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
La presente invención trata acerca de procesos para la preparación de un compuesto de fórmula I: (ver fórmula (I)) el cual comprende hacer reaccionar un compuesto de fórmula IV: (ver fórmula (IV)) con un compuesto de fórmula III o lIlA: (ver fórmulas (III y IIIA)) en presencia de un ácido; en donde R1 es haloalquilo C1-C4 R2 es alquilo sustituido opcionalmente, arilo sustituido opcionalmente o heteroarilo sustituido opcionalmente; R3 es metilo o etilo; R4 es hidrógeno, alquilo sustituido opcionalmente, arilo sustituido opcionalmente o heteroarilo sustituido opcionalmente; y n es 0 o 1.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22900409P | 2009-07-28 | 2009-07-28 | |
| US36157510P | 2010-07-06 | 2010-07-06 | |
| PCT/EP2010/060882 WO2011012618A2 (en) | 2009-07-28 | 2010-07-27 | Processes relating to the alkylation of pyrazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2012001059A true MX2012001059A (es) | 2012-03-14 |
Family
ID=43242901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012001059A MX2012001059A (es) | 2009-07-28 | 2010-07-27 | Procesos relacionados con la alquilacion de pirazoles. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8558006B2 (es) |
| EP (1) | EP2459539B1 (es) |
| JP (1) | JP5763634B2 (es) |
| CN (1) | CN102471278B (es) |
| AR (1) | AR077503A1 (es) |
| BR (1) | BR112012001990B1 (es) |
| ES (1) | ES2602003T3 (es) |
| IL (1) | IL217525A (es) |
| MX (1) | MX2012001059A (es) |
| TW (1) | TW201105636A (es) |
| WO (1) | WO2011012618A2 (es) |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5498624A (en) * | 1995-05-03 | 1996-03-12 | Monsanto Company | Selected pyrazolyl derivatives |
| JP2000044541A (ja) | 1998-08-03 | 2000-02-15 | Mitsui Chemicals Inc | １，３−ジアルキルピラゾール−４−カルボン酸エステルの製造法 |
| JP2000212166A (ja) * | 1999-01-26 | 2000-08-02 | Mitsui Chemicals Inc | １，３―ジアルキルピラゾ―ル―４―カルボン酸エステルの製造法 |
| JP4568404B2 (ja) | 2000-05-17 | 2010-10-27 | 三井化学アグロ株式会社 | ピラゾールカルボン酸エステル誘導体の製造法 |
| GB0224316D0 (en) | 2002-10-18 | 2002-11-27 | Syngenta Participations Ag | Chemical compounds |
| DE10349500A1 (de) * | 2003-10-23 | 2005-06-02 | Bayer Cropscience Ag | Verfahren zum Herstellen von 2-Dihalogenacyl-3-amino-acrylsäureestern und 3-Dihalogenmethyl-pyrazol-4-carbonsäureestern |
| EP1761498A1 (de) * | 2004-06-18 | 2007-03-14 | Basf Aktiengesellschaft | 1-methyl-3-difluormethyl-pyrazol-4-carbonsäure-(ortho-phenyl)-anilide und ihre verwendung als fungizid |
| WO2006045504A1 (en) * | 2004-10-21 | 2006-05-04 | Syngenta Participations Ag | Process for the preparation of pyrazoles |
| CN101133031B (zh) * | 2005-02-25 | 2010-07-21 | 财团法人相模中央化学研究所 | 1-取代-3-氟代烷基吡唑-4-羧酸酯的制造方法 |
| CA2626312C (en) | 2005-10-25 | 2014-10-07 | Hans Tobler | Heterocyclic amide derivatives useful as microbiocides |
| WO2008053044A2 (de) | 2006-11-03 | 2008-05-08 | Basf Se | Hetarylcarbonsäure-n-(biphen-2-yl)amid-verbindungen |
| EP2150536A1 (en) | 2007-05-31 | 2010-02-10 | Syngeta Participations AG | Process for the production of pyrazoles |
| EP2285779B1 (de) | 2008-05-08 | 2013-03-27 | Basf Se | Verfahren zur Herstellung von Arylcarboxamiden |
| GB0812028D0 (en) | 2008-07-01 | 2008-08-06 | Syngenta Participations Ag | Fungicidal compositions |
| CN102099343B (zh) * | 2008-07-21 | 2014-06-04 | 巴斯夫欧洲公司 | 制备1,3-二取代的吡唑羧酸酯的方法 |
| WO2011012620A2 (en) | 2009-07-31 | 2011-02-03 | Syngenta Participations Ag | Processes for the alkylation of pyrazoles |
-
2010
- 2010-07-27 WO PCT/EP2010/060882 patent/WO2011012618A2/en not_active Ceased
- 2010-07-27 JP JP2012522151A patent/JP5763634B2/ja active Active
- 2010-07-27 AR ARP100102715A patent/AR077503A1/es unknown
- 2010-07-27 MX MX2012001059A patent/MX2012001059A/es active IP Right Grant
- 2010-07-27 CN CN201080032550.1A patent/CN102471278B/zh active Active
- 2010-07-27 TW TW099124616A patent/TW201105636A/zh unknown
- 2010-07-27 BR BR112012001990-2A patent/BR112012001990B1/pt active IP Right Grant
- 2010-07-27 EP EP10737321.9A patent/EP2459539B1/en active Active
- 2010-07-27 ES ES10737321.9T patent/ES2602003T3/es active Active
- 2010-07-27 US US13/387,623 patent/US8558006B2/en active Active
-
2012
- 2012-01-12 IL IL217525A patent/IL217525A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CN102471278A (zh) | 2012-05-23 |
| IL217525A (en) | 2016-07-31 |
| IL217525A0 (en) | 2012-02-29 |
| JP2013500309A (ja) | 2013-01-07 |
| US20120203009A1 (en) | 2012-08-09 |
| BR112012001990A2 (pt) | 2015-09-01 |
| TW201105636A (en) | 2011-02-16 |
| BR112012001990B1 (pt) | 2021-02-23 |
| AR077503A1 (es) | 2011-08-31 |
| JP5763634B2 (ja) | 2015-08-12 |
| ES2602003T3 (es) | 2017-02-17 |
| EP2459539A2 (en) | 2012-06-06 |
| WO2011012618A2 (en) | 2011-02-03 |
| US8558006B2 (en) | 2013-10-15 |
| CN102471278B (zh) | 2015-04-01 |
| EP2459539B1 (en) | 2016-08-31 |
| WO2011012618A3 (en) | 2011-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |