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MX2012000202A - Gen plaguicida axmi-205 y metodos para su uso. - Google Patents

Gen plaguicida axmi-205 y metodos para su uso.

Info

Publication number
MX2012000202A
MX2012000202A MX2012000202A MX2012000202A MX2012000202A MX 2012000202 A MX2012000202 A MX 2012000202A MX 2012000202 A MX2012000202 A MX 2012000202A MX 2012000202 A MX2012000202 A MX 2012000202A MX 2012000202 A MX2012000202 A MX 2012000202A
Authority
MX
Mexico
Prior art keywords
plants
compositions
bacteria
pesticidal
methods
Prior art date
Application number
MX2012000202A
Other languages
English (en)
Inventor
Kimberly S Sampson
Daniel J Tomso
Nicholas B Duck
Nalini Desai
Deepa Balusubramanian
Jill Hinson
Duane Alan Lehtinen
Original Assignee
Athenix Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Athenix Corp filed Critical Athenix Corp
Publication of MX2012000202A publication Critical patent/MX2012000202A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8285Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for nematode resistance
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Pest Control & Pesticides (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Composiciones y métodos para conferir actividad plaguicida a bacterias, plantas, células vegetales, tejidos y semillas. Se proveen composiciones que comprenden una secuencia codificante para polipéptidos plaguicidas. Las secuencias codificantes se pueden usar en construcciones de ADN o cassettes de expresión para transformar y expresar en plantas y bacterias. Las composiciones también comprenden bacterias, plantas, células vegetales, tejidos y semillas transformadas. En particular, se proveen moléculas de ácidos nucleicos aisladas plaguicidas. Adicionalmente, se incluyen secuencias de aminoácidos que corresponden a los polinucleótidos. En particular, la presente invención provee moléculas de ácido nucleico que comprenden secuencias de nucleótidos que codifican para la secuencia de aminoácidos mostrada en SEQ ID NO:2, 3, ó 4, la secuencia de nucleótidos detallada en SEO ID NO:1, 9, 10, u 11, así como variantes y fragmentos de la misma.
MX2012000202A 2009-07-02 2010-07-01 Gen plaguicida axmi-205 y metodos para su uso. MX2012000202A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22277809P 2009-07-02 2009-07-02
PCT/US2010/040778 WO2011002992A1 (en) 2009-07-02 2010-07-01 Axmi-205 pesticidal gene and methods for its use

Publications (1)

Publication Number Publication Date
MX2012000202A true MX2012000202A (es) 2012-02-28

Family

ID=42537477

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2014010571A MX346215B (es) 2009-07-02 2010-07-01 Gen plaguicida axmi-205 y metodos para su uso.
MX2012000202A MX2012000202A (es) 2009-07-02 2010-07-01 Gen plaguicida axmi-205 y metodos para su uso.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2014010571A MX346215B (es) 2009-07-02 2010-07-01 Gen plaguicida axmi-205 y metodos para su uso.

Country Status (13)

Country Link
US (4) US8575425B2 (es)
EP (1) EP2449109B1 (es)
CN (1) CN102648281B (es)
AR (1) AR078052A1 (es)
CA (1) CA2766800C (es)
ES (1) ES2609332T3 (es)
HU (1) HUE032365T2 (es)
MX (2) MX346215B (es)
PL (1) PL2449109T3 (es)
RS (1) RS55550B1 (es)
UA (1) UA105046C2 (es)
WO (1) WO2011002992A1 (es)
ZA (1) ZA201200161B (es)

Families Citing this family (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE032365T2 (en) * 2009-07-02 2017-09-28 Athenix Corp AXMI-205 pesticide gene and methods of application
WO2012174271A2 (en) 2011-06-16 2012-12-20 The Regents Of The University Of California Synthetic gene clusters
HUE037346T2 (hu) * 2011-07-28 2018-08-28 Athenix Corp Axmi205 variáns proteinek és alkalmazási eljárások
EP2737068A1 (en) * 2011-07-29 2014-06-04 Athenix Corp. Axmi279 pesticidal gene and methods for its use
WO2013075817A1 (en) 2011-11-21 2013-05-30 Bayer Intellectual Property Gmbh Fungicide n-[(trisubstitutedsilyl)methyl]-carboxamide derivatives
MX2014006350A (es) 2011-11-30 2014-06-23 Bayer Ip Gmbh Derivados de n-bicicloalquil- y n-tricicloalquil-(tio)carboxamida fungicidas.
EP2797891B1 (en) 2011-12-29 2015-09-30 Bayer Intellectual Property GmbH Fungicidal 3-[(pyridin-2-ylmethoxyimino)(phenyl)methyl]-2-substituted-1,2,4-oxadiazol-5(2h)-one derivatives
WO2013098146A1 (en) 2011-12-29 2013-07-04 Bayer Intellectual Property Gmbh Fungicidal 3-[(1,3-thiazol-4-ylmethoxyimino)(phenyl)methyl]-2-substituted-1,2,4-oxadiazol-5(2h)-one derivatives
TWI654180B (zh) 2012-06-29 2019-03-21 美商艾佛艾姆希公司 殺真菌之雜環羧醯胺
BR112015008504A2 (pt) 2012-10-15 2017-08-22 Pioneer Hi Bred Int Método para aumentar a atividade pesticida, polipeptídeo, molécula de ácido nucleico, cassete de expressão, vetor, método de obtenção de uma planta, método de obtenção de uma célula de planta, composição pesticida, método para proteção de uma planta, método para proteger uma planta, método para aumentar a resistência de uma planta
JP6104395B2 (ja) 2012-10-19 2017-03-29 バイエル・クロップサイエンス・アクチェンゲゼルシャフト カルボキサミドまたはチオカルボキサミド誘導体を用いる殺菌剤に対して抵抗性の真菌に対する植物の処理方法
US20150250176A1 (en) 2012-10-19 2015-09-10 Bayer Cropscience Ag Method for enhancing tolerance to abiotic stress in plants using carboxamide or thiocarboxamide derivatives
PL2908640T3 (pl) 2012-10-19 2020-06-29 Bayer Cropscience Ag Sposób stymulowania wzrostu roślin przy pomocy pochodnych karboksamidu
WO2014060502A1 (en) 2012-10-19 2014-04-24 Bayer Cropscience Ag Active compound combinations comprising carboxamide derivatives
US10968446B2 (en) 2012-11-01 2021-04-06 Massachusetts Institute Of Technology Directed evolution of synthetic gene cluster
WO2014153254A2 (en) 2013-03-14 2014-09-25 Pioneer Hi-Bred International Inc. Compositions and methods to control insect pests
CN105473605A (zh) * 2013-03-15 2016-04-06 先锋国际良种公司 Phi-4多肽及其使用方法
US9394345B2 (en) 2013-03-15 2016-07-19 Pioneer Hi-Bred International, Inc. PHI-4 polypeptides and methods for their use
CN105555135B (zh) 2013-04-19 2018-06-15 拜耳作物科学股份公司 涉及邻苯二甲酰胺衍生物应用的用于改善对转基因植物生产潜能的利用的方法
TW201507722A (zh) 2013-04-30 2015-03-01 Bayer Cropscience Ag 做為殺線蟲劑及殺體內寄生蟲劑的n-(2-鹵素-2-苯乙基)-羧醯胺類
WO2014177514A1 (en) 2013-04-30 2014-11-06 Bayer Cropscience Ag Nematicidal n-substituted phenethylcarboxamides
CA2920339C (en) 2013-08-16 2023-10-24 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
DK3041338T3 (da) 2013-09-04 2020-03-16 Indigo Ag Inc Landbrugsmæssige endofytplantesammensætninger og fremgangsmåder til anvendelse
MX359027B (es) 2013-09-13 2018-09-12 Pioneer Hi Bred Int Proteinas insecticidas y metodos para su uso.
BR112016018103B1 (pt) 2014-02-07 2024-01-16 E.I. Du Pont De Nemours And Company Polipeptídeo e seu uso, polinucleotídeo, composição, proteína de fusão, método para controlar uma população, método para inibir o crescimento, método para controlar a infestação, método para obtenção de uma planta ou célula vegetal, construto
US10227608B2 (en) 2014-02-07 2019-03-12 Pioneer Hi-Bred International, Inc. Insecticidal proteins from plants and methods for their use
UY36057A (es) * 2014-03-28 2015-10-30 Monsanto Technology Llc Proteínas pesticidas activas contra insectos coleópteros, acido nucleico recombinante, polipéptido, composición, método para controlar insectos, plantas y sus partes
WO2016000237A1 (en) 2014-07-03 2016-01-07 Pioneer Overseas Corporation Plants having enhanced tolerance to insect pests and related constructs and methods involving insect tolerance genes
CA2961733A1 (en) 2014-09-17 2016-03-24 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
CN107108705B (zh) 2014-10-16 2021-05-25 先锋国际良种公司 杀昆虫蛋白及其使用方法
US10491537B2 (en) * 2014-10-28 2019-11-26 Salesforce.Com, Inc. Facilitating dynamic hierarchical management of queue resources in an on-demand services environment
RU2740312C2 (ru) 2015-01-15 2021-01-13 Пайониэ Хай-Бред Интернешнл, Инк. Инсектицидные белки и способы их применения
CN107529763B (zh) 2015-03-11 2021-08-20 先锋国际良种公司 Pip-72的杀昆虫组合及使用方法
WO2016168289A1 (en) 2015-04-17 2016-10-20 AgBiome, Inc. Pesticidal genes and methods of use
BR112017022852A2 (pt) 2015-04-22 2018-07-17 Agbiome Inc polipeptídeo recombinante com atividade pesticida, composição, molécula de ácido nucleico recombinante, ácido nucleico recombinante, célula hospedeira, construto de dna, vetor, método para controlar uma população de pragas, método para produzir um polipeptídeo, planta, semente transgênica, método para proteger uma planta e método para aumentar o rendimento em uma planta
CN116333064A (zh) 2015-05-19 2023-06-27 先锋国际良种公司 杀昆虫蛋白及其使用方法
EP3960864A3 (en) 2015-06-03 2022-06-15 Agbiome, Inc. Pesticidal genes and methods of use
CN107771181A (zh) 2015-06-16 2018-03-06 先锋国际良种公司 用以防治昆虫有害生物的组合物和方法
RU2742467C2 (ru) 2015-06-22 2021-02-08 Агбайоми, Инк. Пестицидные гены и способы применения
BR112018000729B1 (pt) 2015-07-13 2023-02-07 Pivot Bio, Inc Método de aumento de uma quantidade de nitrogênio atmosférico em uma planta de milho em um campo
BR122023016256B8 (pt) * 2015-08-06 2024-04-30 Du Pont Polipeptídeo inseticida recombinante, polinucleotídeo recombinante, construto de dna, método de obtenção de uma planta transgênica ou célula de planta transgênica, composição, proteína de fusão, método para controlar uma praga, método para inibir crescimento ou para exterminar uma população de pragas e uso do polipeptídeo
CN108513584A (zh) 2015-08-28 2018-09-07 先锋国际良种公司 苍白杆菌介导的植物转化
CN108291219B (zh) 2015-10-05 2023-02-17 麻省理工学院 使用重构nif簇的氮固定
WO2017105987A1 (en) 2015-12-18 2017-06-22 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
MA44159A (fr) 2015-12-22 2018-10-31 Agbiome Inc Gènes pesticides et leurs procédés d'utilisation
WO2017180715A2 (en) 2016-04-14 2017-10-19 Pioneer Hi-Bred International, Inc. Insecticidal polypeptides having improved activity spectrum and uses thereof
CN109072249B (zh) 2016-04-19 2023-08-18 先锋国际良种公司 具有改善的活性谱的多肽的杀昆虫组合及其用途
EP3960863B1 (en) 2016-05-04 2024-11-13 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
US20190185867A1 (en) 2016-06-16 2019-06-20 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
RU2019101793A (ru) 2016-06-24 2020-07-24 Пайонир Хай-Бред Интернэшнл, Инк. Регуляторные элементы растений и способы их применения
CN109788735A (zh) 2016-07-01 2019-05-21 先锋国际良种公司 来自植物的杀昆虫蛋白及其使用方法
US20210292778A1 (en) 2016-07-12 2021-09-23 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
EP3510159B1 (en) 2016-09-06 2023-03-01 AgBiome, Inc. Pesticidal genes and methods of use
CA3038806A1 (en) 2016-11-01 2018-05-11 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
WO2018111551A1 (en) 2016-12-14 2018-06-21 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
EP3558004A1 (en) 2016-12-22 2019-10-30 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
PT3568022T (pt) * 2017-01-12 2022-08-30 Syngenta Participations Ag Proteínas inseticidas
MX2019008285A (es) 2017-01-12 2019-11-11 Pivot Bio Inc Métodos y composiciones para mejorar atributos de plantas.
WO2018140214A1 (en) 2017-01-24 2018-08-02 Pioneer Hi-Bred International, Inc. Nematicidal protein from pseudomonas
BR112019015582A2 (pt) 2017-01-30 2020-03-10 AgBiome, Inc. Genes pesticidas e métodos de uso
WO2018148001A1 (en) 2017-02-08 2018-08-16 Pioneer Hi-Bred International Inc Insecticidal combinations of plant derived insecticidal proteins and methods for their use
CA3058757A1 (en) 2017-04-11 2018-10-18 AgBiome, Inc. Pesticidal genes and methods of use
US11555203B2 (en) 2017-05-11 2023-01-17 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
CA3064884A1 (en) 2017-05-26 2018-11-29 Pioneer Hi-Bred International, Inc. Insecticidal polypeptides having improved activity spectrum and uses thereof
BR112020002279A2 (pt) 2017-08-03 2020-07-28 AgBiome, Inc. genes pesticidas e métodos de uso
CN111148432B (zh) * 2017-10-02 2021-11-23 先正达参股股份有限公司 工程化的杀有害生物蛋白和控制植物有害生物的方法
WO2019074598A1 (en) 2017-10-13 2019-04-18 Pioneer Hi-Bred International, Inc. VIRUS-INDUCED GENETIC SILENCING TECHNOLOGY FOR THE CONTROL OF INSECTS IN MAIZE
MX2020004344A (es) 2017-10-25 2020-10-14 Pivot Bio Inc Objetivos genéticos para el direccionamiento de fijación de nitrógeno para mejorar los rasgos de las plantas.
MX2020004343A (es) 2017-10-25 2021-01-08 Pivot Bio Inc Métodos y composiciones para mejorar microbios modificados que fijan nitrógeno.
US10907173B2 (en) 2017-12-22 2021-02-02 AgBiome, Inc. Pesticidal genes and methods of use
KR20200123144A (ko) 2018-02-22 2020-10-28 지머젠 인코포레이티드 바실러스가 농축된 게놈 라이브러리를 생성하고 새로운 cry 독소를 동정하기 위한 방법
BR112020017975A2 (pt) 2018-03-02 2020-12-29 Zymergen Inc. Plataforma de descoberta de proteína inseticida e proteínas inseticidas descobertas a partir da mesma
EP3759489A1 (en) 2018-03-02 2021-01-06 Pioneer Hi-Bred International, Inc. Plant health assay
WO2019178038A1 (en) 2018-03-14 2019-09-19 Pioneer Hi-Bred International, Inc. Insecticidal proteins from plants and methods for their use
CN115850420A (zh) 2018-03-14 2023-03-28 先锋国际良种公司 来自植物的杀昆虫蛋白及其使用方法
EP3781692A1 (en) 2018-04-20 2021-02-24 Agbiome, Inc. Pesticidal proteins and methods of use
CA3096516A1 (en) 2018-05-22 2019-11-28 Pioneer Hi-Bred International, Inc. Plant regulatory elements and methods of use thereof
CN112513033A (zh) 2018-06-04 2021-03-16 拜耳公司 除草活性的双环苯甲酰基吡唑
IL279222B2 (en) 2018-06-05 2025-10-01 Lifeedit Inc RNA-guided nucleases and active variant fragments thereof and methods of use
WO2020006064A2 (en) 2018-06-27 2020-01-02 Pivot Bio, Inc. Agricultural compositions comprising remodeled nitrogen fixing microbes
MX2021000187A (es) 2018-07-11 2021-06-15 Pivot Bio Inc Suministro de nitrógeno dinámico temporal y espacialmente dirigido mediante microbios remodelados.
CN112689677B (zh) 2018-08-29 2024-09-03 先锋国际良种公司 杀昆虫蛋白及其使用方法
NZ778392A (en) 2018-12-27 2025-11-28 Life Edit Therapeutics Inc Polypeptides useful for gene editing and methods of use
WO2020190363A1 (en) 2019-03-19 2020-09-24 Massachusetts Institute Of Technology Control of nitrogen fixation in rhizobia that associate with cereals
KR20220062289A (ko) 2019-08-12 2022-05-16 라이프에디트 테라퓨틱스, 인크. Rna-가이드된 뉴클레아제 및 그의 활성 단편 및 변이체 및 사용 방법
WO2021076346A1 (en) 2019-10-18 2021-04-22 Pioneer Hi-Bred International, Inc. Maize event dp-202216-6 and dp-023211-2 stack
CA3163285A1 (en) 2019-12-30 2021-07-08 Alexandra Briner CRAWLEY Rna-guided nucleases and active fragments and variants thereof and methods of use
CN115697044A (zh) 2020-03-31 2023-02-03 艾洛生物系统有限公司 西瓜和其他葫芦科中内源罗汉果苷途径基因的调控
TW202208626A (zh) 2020-04-24 2022-03-01 美商生命編輯公司 Rna引導核酸酶及其活性片段與變體,以及使用方法
EP4143293A1 (en) 2020-05-01 2023-03-08 Pivot Bio, Inc. Measurement of nitrogen fixation and incorporation
CA3173882A1 (en) 2020-05-11 2021-11-18 Alexandra Briner CRAWLEY Rna-guided nucleic acid binding proteins and active fragments and variants thereof and methods of use
BR112022027035A2 (pt) 2020-07-14 2023-04-11 Pioneer Hi Bred Int Proteínas inseticidas e métodos para uso das mesmas
WO2022015969A1 (en) 2020-07-15 2022-01-20 LifeEDIT Therapeutics, Inc. Uracil stabilizing proteins and active fragments and variants thereof and methods of use
BR112023002603A2 (pt) 2020-08-10 2023-04-04 Pioneer Hi Bred Int Elementos reguladores de plantas e métodos de uso dos mesmos
MX2023002848A (es) 2020-09-11 2023-03-22 Lifeedit Therapeutics Inc Enzimas modificadoras del acido desoxirribonucleico (adn) y fragmentos activos y sus variantes y metodos de uso.
US20240060079A1 (en) 2020-10-23 2024-02-22 Elo Life Systems Methods for producing vanilla plants with improved flavor and agronomic production
WO2022115524A2 (en) 2020-11-24 2022-06-02 AgBiome, Inc. Pesticidal genes and methods of use
TW202300649A (zh) 2021-03-22 2023-01-01 美商生命編輯治療學公司 Dna修飾酶及活性片段及其變體及使用方法
BR112023023044A2 (pt) 2021-05-06 2024-01-23 Agbiome Inc Genes pesticidas e métodos de uso
EP4352215A1 (en) 2021-06-11 2024-04-17 LifeEDIT Therapeutics, Inc. Rna polymerase iii promoters and methods of use
EP4444890A1 (en) 2021-12-07 2024-10-16 Agbiome, Inc. Pesticidal genes and methods of use
WO2023141602A2 (en) 2022-01-21 2023-07-27 Renagade Therapeutics Management Inc. Engineered retrons and methods of use
IL314488A (en) 2022-01-24 2024-09-01 Lifeedit Therapeutics Inc RNA-directed nucleases and active fragments and their variants and methods of use
CN118843637A (zh) 2022-02-11 2024-10-25 东北农业大学 用于增加植物中蛋白质和/或油含量和改变油特性的方法和组合物
CN120344660A (zh) 2022-07-18 2025-07-18 雷纳嘉德医疗管理公司 基因编辑组分、系统和使用方法
CA3264752A1 (en) 2022-08-12 2024-02-15 Life Edit Therapeutics, Inc. RNA-GUIDED NUCLEASE AND ACTIVE FRAGMENTS, ASSOCIATED VARIANTS AND METHODS OF USE
WO2024044596A1 (en) 2022-08-23 2024-02-29 AgBiome, Inc. Pesticidal genes and methods of use
WO2024044723A1 (en) 2022-08-25 2024-02-29 Renagade Therapeutics Management Inc. Engineered retrons and methods of use
TW202424186A (zh) 2022-08-25 2024-06-16 美商生命編輯治療學公司 Rna引導核酸酶中介基因編輯用之具鎖核酸引導 rna之化學修飾
AU2023374241A1 (en) 2022-11-04 2025-06-12 Life Edit Therapeutics, Inc. Evolved adenine deaminases and rna-guided nuclease fusion proteins with internal insertion sites and methods of use
AR131334A1 (es) 2022-12-13 2025-03-12 Ag Biome Inc Genes plaguicidas y métodos de uso
WO2025022367A2 (en) 2023-07-27 2025-01-30 Life Edit Therapeutics, Inc. Rna-guided nucleases and active fragments and variants thereof and methods of use
WO2025052302A1 (en) 2023-09-05 2025-03-13 Mazen Animal Health, Inc. Methods and compositions for the production of mannanase in plants
WO2025074304A1 (en) 2023-10-03 2025-04-10 Mazen Animal Health, Inc. Compositions and methods for in planta production of a porcine circovirus vaccine
WO2025081042A1 (en) 2023-10-12 2025-04-17 Renagade Therapeutics Management Inc. Nickase-retron template-based precision editing system and methods of use
WO2025083619A1 (en) 2023-10-18 2025-04-24 Life Edit Therapeutics, Inc. Rna-guided nucleases and acive fragments and variants thereof and methods of use
WO2025155753A2 (en) 2024-01-17 2025-07-24 Renagade Therapeutics Management Inc. Improved gene editing system, guides, and methods
WO2025174908A1 (en) 2024-02-12 2025-08-21 Life Edit Therapeutics, Inc. Novel rna-guided nucleases and proteins for polymerase editing
WO2025178772A1 (en) 2024-02-23 2025-08-28 Genective Sa Insecticidal proteins compositions and methods of use
WO2025193453A1 (en) 2024-03-14 2025-09-18 Genective Sa Insecticidal proteins compositions and methods of use
WO2025235220A1 (en) 2024-05-08 2025-11-13 Genective Sa Insecticidal proteins compositions and methods of use
WO2025264577A1 (en) 2024-06-20 2025-12-26 Genective Sa Insecticidal proteins, compositions and methods of use
WO2025264584A1 (en) 2024-06-20 2025-12-26 Genective Sa Insecticidal proteins, compositions and methods of use
WO2026006045A1 (en) 2024-06-25 2026-01-02 Genective Sa Insecticidal proteins, compositions and methods of use
WO2026003754A1 (en) 2024-06-25 2026-01-02 Life Edit Therapeutics, Inc. Novel reverse transcriptases and uses thereof

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US15066A (en) 1856-06-10 Machine for rubbing and polishing painted cloth
US2694101A (en) 1950-09-29 1954-11-09 Bell Telephone Labor Inc Vibration damper for transmission lines
US4196265A (en) 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
US5380831A (en) 1986-04-04 1995-01-10 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5039523A (en) 1988-10-27 1991-08-13 Mycogen Corporation Novel Bacillus thuringiensis isolate denoted B.t. PS81F, active against lepidopteran pests, and a gene encoding a lepidopteran-active toxin
US5240842A (en) 1989-07-11 1993-08-31 Biotechnology Research And Development Corporation Aerosol beam microinjector
EP0482125A1 (en) 1989-07-11 1992-04-29 Biotechnology Research And Development Corporation Aerosol beam microinjection
CA2051562C (en) 1990-10-12 2003-12-02 Jewel M. Payne Bacillus thuringiensis isolates active against dipteran pests
TW261517B (es) 1991-11-29 1995-11-01 Mitsubishi Shozi Kk
US5743477A (en) 1992-08-27 1998-04-28 Dowelanco Insecticidal proteins and method for plant protection
US5849870A (en) * 1993-03-25 1998-12-15 Novartis Finance Corporation Pesticidal proteins and strains
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US6468523B1 (en) 1998-11-02 2002-10-22 Monsanto Technology Llc Polypeptide compositions toxic to diabrotic insects, and methods of use
WO2001016305A2 (en) * 1999-09-02 2001-03-08 Agresearch Limited Nucleotide sequences encoding an insectidal protein complex from serratia
CA2396392C (en) 1999-11-29 2015-04-21 Midwest Oilseeds, Inc. Methods and compositions for the introduction of molecules into cells
US20050183161A1 (en) * 2003-10-14 2005-08-18 Athenix Corporation AXMI-010, a delta-endotoxin gene and methods for its use
EP3150625B1 (en) 2006-06-15 2021-01-27 BASF Agricultural Solutions Seed US LLC A family of pesticidal proteins and methods for their use
EA201070371A1 (ru) 2007-10-16 2011-02-28 Атеникс Корпорейшн Axmi-066 и axmi-076: дельта-эндотоксиновые белки и способы их применения
BRPI1007915B1 (pt) 2009-02-05 2019-05-14 Athenix Corporation Genes de variante axmi-r1 delta-endotoxina, vetor, célula hospedeira microbiana, polipeptídeo recombinante e seu método de produção, composição, e métodos para controlar e matar uma população de peste de coleópteros, 5 e para protegeruma planta de uma peste
EA026111B1 (ru) 2009-02-27 2017-03-31 Атеникс Корпорейшн Пестицидные белки и способы их применения
CN102421792B (zh) 2009-03-11 2015-11-25 阿森尼克斯公司 Axmi-001、axmi-002、axmi-030、axmi-035和axmi-045: 来自苏云金芽孢杆菌的杀虫蛋白及其用法
HUE032365T2 (en) * 2009-07-02 2017-09-28 Athenix Corp AXMI-205 pesticide gene and methods of application

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MX346215B (es) 2017-03-10
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