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MX2011008389A - Sal de tipo tosilato de un derivado de 5-pirazolil-2-piridona, util en el tratamiento de la enfermedad pulmonar obstructiva cronica (epoc). - Google Patents

Sal de tipo tosilato de un derivado de 5-pirazolil-2-piridona, util en el tratamiento de la enfermedad pulmonar obstructiva cronica (epoc).

Info

Publication number
MX2011008389A
MX2011008389A MX2011008389A MX2011008389A MX2011008389A MX 2011008389 A MX2011008389 A MX 2011008389A MX 2011008389 A MX2011008389 A MX 2011008389A MX 2011008389 A MX2011008389 A MX 2011008389A MX 2011008389 A MX2011008389 A MX 2011008389A
Authority
MX
Mexico
Prior art keywords
copd
pyrazolyl
useful
treatment
tosylate salt
Prior art date
Application number
MX2011008389A
Other languages
English (en)
Inventor
Lars-Erik Briggner
Andrew James Watts
Marie-Lyne Alcaraz
Per Tomas Klingstedt
Hans Roland Loenn
Helena Nicklasson
Robert Anthony Nixon
Robert Zuban
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42046174&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2011008389(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MX2011008389A publication Critical patent/MX2011008389A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se describe el 4-metilbencenosulfonato de 6-metil-5-(1-metil-1H-pi razol-5-il)-N-{[5-(metilsulfonil)piridin-2-il]metil}-2-oxo1-[3-(t rifluorometil)fenil]-1,2-dihidropiridin-3-carboxamida y una forma cristalina novedosa de éste, junto con procesos para preparar la sal y la forma, composiciones farmacéuticas que comprenden la forma y el uso de la sal y la forma en terapia.
MX2011008389A 2009-02-20 2010-02-18 Sal de tipo tosilato de un derivado de 5-pirazolil-2-piridona, util en el tratamiento de la enfermedad pulmonar obstructiva cronica (epoc). MX2011008389A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15409909P 2009-02-20 2009-02-20
PCT/GB2010/050271 WO2010094964A1 (en) 2009-02-20 2010-02-18 Tosylate salt of a 5-pyrazolyl-2-pyridone derivative, useful in the treatment of copd

Publications (1)

Publication Number Publication Date
MX2011008389A true MX2011008389A (es) 2011-09-01

Family

ID=42046174

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011008389A MX2011008389A (es) 2009-02-20 2010-02-18 Sal de tipo tosilato de un derivado de 5-pirazolil-2-piridona, util en el tratamiento de la enfermedad pulmonar obstructiva cronica (epoc).

Country Status (15)

Country Link
US (2) US8232296B2 (es)
EP (1) EP2398792B1 (es)
JP (1) JP5543982B2 (es)
KR (1) KR20110127158A (es)
CN (1) CN102405219B (es)
AR (1) AR075523A1 (es)
AU (1) AU2010215269B2 (es)
BR (1) BRPI1008396B8 (es)
CA (1) CA2752319C (es)
ES (1) ES2469916T3 (es)
MX (1) MX2011008389A (es)
RU (1) RU2526038C2 (es)
TW (1) TW201036957A (es)
UY (1) UY32461A (es)
WO (1) WO2010094964A1 (es)

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Also Published As

Publication number Publication date
BRPI1008396A2 (pt) 2017-06-27
AU2010215269A1 (en) 2011-08-25
UY32461A (es) 2010-09-30
CA2752319C (en) 2016-10-04
KR20110127158A (ko) 2011-11-24
JP5543982B2 (ja) 2014-07-09
BRPI1008396B8 (pt) 2021-05-25
EP2398792B1 (en) 2014-04-09
TW201036957A (en) 2010-10-16
WO2010094964A1 (en) 2010-08-26
BRPI1008396B1 (pt) 2020-11-10
ES2469916T3 (es) 2014-06-20
US20100216843A1 (en) 2010-08-26
CN102405219A (zh) 2012-04-04
AU2010215269B2 (en) 2013-06-27
US20120269872A1 (en) 2012-10-25
AR075523A1 (es) 2011-04-06
CA2752319A1 (en) 2010-08-26
CN102405219B (zh) 2013-11-06
JP2012518623A (ja) 2012-08-16
RU2526038C2 (ru) 2014-08-20
EP2398792A1 (en) 2011-12-28
US8232296B2 (en) 2012-07-31
RU2011135627A (ru) 2013-03-27
HK1162498A1 (en) 2012-08-31

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