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MX2010010122A - Polipeptido que tiene actividad de glioxalasa iii, polinucleotido que codifica para el mismo, y usos de los mismos. - Google Patents

Polipeptido que tiene actividad de glioxalasa iii, polinucleotido que codifica para el mismo, y usos de los mismos.

Info

Publication number
MX2010010122A
MX2010010122A MX2010010122A MX2010010122A MX2010010122A MX 2010010122 A MX2010010122 A MX 2010010122A MX 2010010122 A MX2010010122 A MX 2010010122A MX 2010010122 A MX2010010122 A MX 2010010122A MX 2010010122 A MX2010010122 A MX 2010010122A
Authority
MX
Mexico
Prior art keywords
polypeptide
iii activity
glyoxalase iii
same
polynucleotide encoding
Prior art date
Application number
MX2010010122A
Other languages
English (en)
Inventor
Philippe Soucaille
Francois Voelker
Original Assignee
Metabolic Explorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolic Explorer Sa filed Critical Metabolic Explorer Sa
Publication of MX2010010122A publication Critical patent/MX2010010122A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La presente invención se refiere a un polipéptido novedoso que tiene la actividad enzimática de conversión de metilglioxal a ácido láctico en un sólo paso (conocida como actividad de glioxalasa III), un polinucleótido que tiene una secuencia de nucleótidos que codifica para dicho polipéptido, y usos de los mismos; la invención se refiere a la modulación de la actividad de glioxalasa III en un microorganismo, haciendo variar el nivel de expresión del polinucleótido que codifica para dicho polipéptido; la invención se refiere también a la producción de químicos de utilidad, especialmente 1,2-propanodiol, acetol y ácido láctico por microorganismos fermentantes, en donde su actividad de glioxalasa III es modulada.
MX2010010122A 2008-03-18 2009-03-16 Polipeptido que tiene actividad de glioxalasa iii, polinucleotido que codifica para el mismo, y usos de los mismos. MX2010010122A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2008/053224 WO2009115114A1 (en) 2008-03-18 2008-03-18 Polypeptide having glyoxylase iii activity, polynucleotide encoding the same and uses thereof
PCT/EP2009/053093 WO2009115497A1 (en) 2008-03-18 2009-03-16 Polypeptide having glyoxalase iii activity, polynucleotide encoding the same and uses thereof

Publications (1)

Publication Number Publication Date
MX2010010122A true MX2010010122A (es) 2010-10-04

Family

ID=39356525

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010010122A MX2010010122A (es) 2008-03-18 2009-03-16 Polipeptido que tiene actividad de glioxalasa iii, polinucleotido que codifica para el mismo, y usos de los mismos.

Country Status (11)

Country Link
US (1) US20110014666A1 (es)
JP (1) JP2011515083A (es)
KR (1) KR20100124332A (es)
CN (1) CN101978052A (es)
BR (1) BRPI0909756A2 (es)
CA (1) CA2715737A1 (es)
IL (1) IL207648A0 (es)
MX (1) MX2010010122A (es)
RU (1) RU2010140227A (es)
TW (1) TW201005094A (es)
WO (2) WO2009115114A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
KR20250153869A (ko) 2011-12-30 2025-10-27 필립모리스 프로덕츠 에스.에이. 공기 흐름 검출을 구비하는 에어로졸 발생 장치
KR102092422B1 (ko) * 2012-01-30 2020-03-24 피티티 글로벌 케미컬 퍼블릭 컴퍼니 리미티드 유전자 조작된 미생물로부터 뮤콘산의 생산
CN102719462B (zh) * 2012-05-16 2013-10-16 黑龙江大学 甜菜单体附加系m14品系乙二醛酶i基因及其编码蛋白
CN102994577B (zh) * 2012-10-26 2015-01-21 上海交通大学 微生物细胞转化法生产丙酮醇的方法
IL224101A (en) * 2013-01-03 2014-11-30 Solight Ltd Electromagnetic Radiation System
CN105734002B (zh) * 2014-12-10 2019-06-25 中粮集团有限公司 一种重组谷氨酸生产菌株及其制备方法与应用
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US10301653B2 (en) * 2015-07-06 2019-05-28 Wisconsin Alumni Research Foundation Microorganisms that co-consume glucose with non-glucose carbohydrates and methods of use
EP3196312B1 (en) * 2016-01-25 2020-01-15 Metabolic Explorer Efficient conversion of methylglyoxal into hydroxyacetone using novel enzymes and appli cations thereof
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
FR3090691B1 (fr) * 2018-12-20 2023-06-09 Ifp Energies Now Bacteries clostridium genetiquement modifiees, preparation et utilisations de celles-ci
CN119775372A (zh) * 2024-12-30 2025-04-08 宁夏伊品生物科技股份有限公司 Hsp31蛋白质及其相关生物材料在提高大肠杆菌氨基酸产量中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6087140A (en) * 1997-02-19 2000-07-11 Wisconsin Alumni Research Foundation Microbial production of 1,2-propanediol from sugar
US7300787B2 (en) * 2002-07-05 2007-11-27 Archer-Daniels-Midland Company Lactobacillus strains and use thereof in fermentation for L-lactic acid production
US20050112737A1 (en) * 2003-11-20 2005-05-26 A. E. Staley Manufacturing Co. Lactic acid producing yeast
FR2864967B1 (fr) * 2004-01-12 2006-05-19 Metabolic Explorer Sa Microorganisme evolue pour la production de 1,2-propanediol

Also Published As

Publication number Publication date
TW201005094A (en) 2010-02-01
KR20100124332A (ko) 2010-11-26
WO2009115497A1 (en) 2009-09-24
CN101978052A (zh) 2011-02-16
CA2715737A1 (en) 2009-09-24
IL207648A0 (en) 2010-12-30
RU2010140227A (ru) 2012-04-27
BRPI0909756A2 (pt) 2015-08-25
WO2009115114A1 (en) 2009-09-24
US20110014666A1 (en) 2011-01-20
JP2011515083A (ja) 2011-05-19

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