MX2010005080A - Metodos y composiciones para determinar la sensibilidad de linfoma de celula b al tratamiento con anticuerpos anti-cd40. - Google Patents
Metodos y composiciones para determinar la sensibilidad de linfoma de celula b al tratamiento con anticuerpos anti-cd40.Info
- Publication number
- MX2010005080A MX2010005080A MX2010005080A MX2010005080A MX2010005080A MX 2010005080 A MX2010005080 A MX 2010005080A MX 2010005080 A MX2010005080 A MX 2010005080A MX 2010005080 A MX2010005080 A MX 2010005080A MX 2010005080 A MX2010005080 A MX 2010005080A
- Authority
- MX
- Mexico
- Prior art keywords
- antibodies
- treatment
- cell lymphoma
- compositions
- methods
- Prior art date
Links
- 208000003950 B-cell lymphoma Diseases 0.000 title abstract 2
- 230000004043 responsiveness Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La invención provee métodos y kits útiles para predecir o determinar la sensibilidad de linfoma de célula B al tratamiento con anticuerpos anti-CD40.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98627707P | 2007-11-07 | 2007-11-07 | |
| PCT/US2008/082920 WO2009062125A1 (en) | 2007-11-07 | 2008-11-07 | Methods and compositions for assessing responsiveness of b-cell lymphoma to treatment with anti-cd40 antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010005080A true MX2010005080A (es) | 2010-07-28 |
Family
ID=40377361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010005080A MX2010005080A (es) | 2007-11-07 | 2008-11-07 | Metodos y composiciones para determinar la sensibilidad de linfoma de celula b al tratamiento con anticuerpos anti-cd40. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9068230B2 (es) |
| EP (1) | EP2222875B1 (es) |
| JP (2) | JP5730576B2 (es) |
| KR (1) | KR101620642B1 (es) |
| CN (1) | CN101910414B (es) |
| AU (1) | AU2008323701B2 (es) |
| BR (1) | BRPI0820707A2 (es) |
| CA (1) | CA2704499C (es) |
| IL (1) | IL205391A (es) |
| MX (1) | MX2010005080A (es) |
| WO (1) | WO2009062125A1 (es) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9075066B2 (en) * | 2008-04-21 | 2015-07-07 | Korea Research Institute Of Bioscience And Biotechnology | CST1, DCC1, IFITM1 or MELK as markers for diagnosing stomach cancer |
| US8628927B2 (en) | 2008-11-07 | 2014-01-14 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| US8748103B2 (en) | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
| US9506119B2 (en) | 2008-11-07 | 2016-11-29 | Adaptive Biotechnologies Corp. | Method of sequence determination using sequence tags |
| SG195652A1 (en) | 2008-11-07 | 2013-12-30 | Sequenta Inc | Methods of monitoring conditions by sequence analysis |
| US9528160B2 (en) | 2008-11-07 | 2016-12-27 | Adaptive Biotechnolgies Corp. | Rare clonotypes and uses thereof |
| ES2568509T3 (es) | 2009-01-15 | 2016-04-29 | Adaptive Biotechnologies Corporation | Perfilado de la inmunidad adaptativa y métodos para la generación de anticuerpos monoclonales |
| US9617600B2 (en) | 2009-04-18 | 2017-04-11 | Genentech, Inc. | Methods for assessing responsiveness of B-cell lymphoma to treatment with anti-CD40 antibodies |
| EP2446052B1 (en) | 2009-06-25 | 2018-08-08 | Fred Hutchinson Cancer Research Center | Method of measuring adaptive immunity |
| WO2011157678A1 (en) * | 2010-06-14 | 2011-12-22 | Qiagen Gmbh | Method for determination of target cells or tissue for extraction of biomolecules from fixed biological samples |
| MX353143B (es) | 2011-02-28 | 2017-12-20 | Genentech Inc | Marcadores biologicos y metodos para pronosticar respuesta a antagonistas de celulas b. |
| US8592156B2 (en) * | 2011-08-08 | 2013-11-26 | Roche Molecular Systems, Inc. | Predicting response to anti-CD20 therapy in DLBCL patients |
| WO2013036459A2 (en) * | 2011-09-09 | 2013-03-14 | Sequenta, Inc. | Sequence-based measures of immune response |
| US10385475B2 (en) | 2011-09-12 | 2019-08-20 | Adaptive Biotechnologies Corp. | Random array sequencing of low-complexity libraries |
| CA2853088C (en) | 2011-10-21 | 2018-03-13 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| CA2858070C (en) | 2011-12-09 | 2018-07-10 | Adaptive Biotechnologies Corporation | Diagnosis of lymphoid malignancies and minimal residual disease detection |
| US9499865B2 (en) | 2011-12-13 | 2016-11-22 | Adaptive Biotechnologies Corp. | Detection and measurement of tissue-infiltrating lymphocytes |
| JP6302847B2 (ja) | 2012-03-05 | 2018-03-28 | アダプティヴ バイオテクノロジーズ コーポレーション | 頻度が一致したサブユニットからの、対をなす免疫受容体鎖の決定 |
| SG10201507700VA (en) | 2012-05-08 | 2015-10-29 | Adaptive Biotechnologies Corp | Compositions and method for measuring and calibrating amplification bias in multiplexed pcr reactions |
| CA2886647A1 (en) | 2012-10-01 | 2014-04-10 | Adaptive Biotechnologies Corporation | Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization |
| US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
| KR102357699B1 (ko) | 2013-11-06 | 2022-02-04 | 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 | 발현 프로파일링에 의한 림프종 유형의 하위유형 분류 방법 |
| CA2941612A1 (en) | 2014-03-05 | 2015-09-11 | Adaptive Biotechnologies Corporation | Methods using randomer-containing synthetic molecules |
| CN106102767B (zh) | 2014-03-27 | 2021-08-10 | 豪夫迈·罗氏有限公司 | 用于诊断和治疗炎症性肠病的方法 |
| US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
| ES2777529T3 (es) | 2014-04-17 | 2020-08-05 | Adaptive Biotechnologies Corp | Cuantificación de genomas de células inmunitarias adaptativas en una mezcla compleja de células |
| EP3831847A1 (en) | 2014-10-29 | 2021-06-09 | Seagen Inc. | Dosage and administration of non-fucosylated anti-cd40 antibodies |
| US10392663B2 (en) | 2014-10-29 | 2019-08-27 | Adaptive Biotechnologies Corp. | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from a large number of samples |
| US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
| EP3498866A1 (en) | 2014-11-25 | 2019-06-19 | Adaptive Biotechnologies Corp. | Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing |
| ES2858306T3 (es) | 2015-02-24 | 2021-09-30 | Adaptive Biotechnologies Corp | Método para determinar el estado de HLA mediante secuenciación del repertorio inmunitario |
| WO2016161273A1 (en) | 2015-04-01 | 2016-10-06 | Adaptive Biotechnologies Corp. | Method of identifying human compatible t cell receptors specific for an antigenic target |
| WO2017017283A1 (en) | 2015-07-30 | 2017-02-02 | Qiagen Gmbh | Method of preparing a frozen biological sample |
| DK3359688T3 (da) * | 2015-10-05 | 2021-08-23 | Biogen Ma Inc | Molekylære signaturer til anvendelse til diagnose og analyse af respons på behandling af autoimmune sygdomme |
| JP7312552B2 (ja) * | 2016-05-16 | 2023-07-21 | ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム | ナノ粒子としてのtRNA送達用組成物およびその使用方法 |
| EP3471754A1 (en) | 2016-06-20 | 2019-04-24 | Kymab Limited | Anti-pd-l1 antibodies |
| US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
| KR102364599B1 (ko) * | 2017-04-04 | 2022-02-21 | 에프. 호프만-라 로슈 아게 | Cd40 및 fap에 특이적으로 결합할 수 있는 새로운 이중특이적 항원 결합 분자 |
| US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
| WO2022120038A1 (en) * | 2020-12-02 | 2022-06-09 | Albert Einstein College Of Medicine | Method for predicting patient response to cd40-targeted therapies |
Family Cites Families (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4018653A (en) | 1971-10-29 | 1977-04-19 | U.S. Packaging Corporation | Instrument for the detection of Neisseria gonorrhoeae without culture |
| US4016043A (en) | 1975-09-04 | 1977-04-05 | Akzona Incorporated | Enzymatic immunological method for the determination of antigens and antibodies |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4318980A (en) | 1978-04-10 | 1982-03-09 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a cycling reactant as label |
| US4424279A (en) | 1982-08-12 | 1984-01-03 | Quidel | Rapid plunger immunoassay method and apparatus |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
| US5182368A (en) | 1986-06-13 | 1993-01-26 | Ledbetter Jeffrey A | Ligands and methods for augmenting B-cell proliferation |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| US5700637A (en) | 1988-05-03 | 1997-12-23 | Isis Innovation Limited | Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| WO1996033735A1 (en) | 1995-04-27 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| ATE139258T1 (de) | 1990-01-12 | 1996-06-15 | Cell Genesys Inc | Erzeugung xenogener antikörper |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| DK0814159T3 (da) | 1990-08-29 | 2005-10-24 | Genpharm Int | Transgene, ikke-humane dyr, der er i stand til at danne heterologe antistoffer |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| DE122004000008I1 (de) | 1991-06-14 | 2005-06-09 | Genentech Inc | Humanisierter Heregulin Antikörper. |
| US5874082A (en) | 1992-07-09 | 1999-02-23 | Chiron Corporation | Humanized anti-CD40 monoclonal antibodies and fragments capable of blocking B cell proliferation |
| NZ278740A (en) | 1993-12-23 | 1998-05-27 | Immunex Corp | Treating disease characterised by neoplastic cells expressing cd40 using a cd40 binding protein |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| GB9425060D0 (en) | 1994-12-13 | 1995-02-08 | Univ Birmingham | Carcinoma treatment |
| WO1996034096A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| DE19544393A1 (de) | 1995-11-15 | 1997-05-22 | Hoechst Schering Agrevo Gmbh | Synergistische herbizide Mischungen |
| JP4215172B2 (ja) | 1996-12-03 | 2009-01-28 | アムジェン フレモント インク. | 複数のV▲下H▼およびV▲下κ▼領域を含むヒトIg遺伝子座を有するトランスジェニック哺乳動物、ならびにそれから産生される抗体 |
| US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
| US6946129B1 (en) | 1999-06-08 | 2005-09-20 | Seattle Genetics, Inc. | Recombinant anti-CD40 antibody and uses thereof |
| US6248535B1 (en) | 1999-12-20 | 2001-06-19 | University Of Southern California | Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens |
| AU2001249727A1 (en) | 2000-03-31 | 2001-10-15 | Genentech, Inc. | Compositions and methods for detecting and quantifying gene expression |
| WO2001083755A2 (en) | 2000-04-28 | 2001-11-08 | La Jolla Institute For Allergy And Immunology | Human anti-cd40 antibodies and methods of making and using same |
| ATE507839T1 (de) | 2001-04-02 | 2011-05-15 | Genentech Inc | Kombinationstherapie |
| JP4025881B2 (ja) * | 2001-04-27 | 2007-12-26 | キリンファーマ株式会社 | 抗cd40モノクローナル抗体 |
| AR039067A1 (es) | 2001-11-09 | 2005-02-09 | Pfizer Prod Inc | Anticuerpos para cd40 |
| AU2004211955B2 (en) * | 2003-02-06 | 2009-05-14 | Cedars-Sinai Medical Center | Gene expression markers for response to EGFR inhibitor drugs |
| US7767387B2 (en) * | 2003-06-13 | 2010-08-03 | Sagres Discovery, Inc. | Therapeutic targets in cancer |
| EP2157524A3 (en) * | 2003-09-03 | 2010-12-08 | GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Methods for identifying, diagnosing, and predicting survival of lymphomas |
| EP2149585B1 (en) | 2003-11-04 | 2013-08-14 | Novartis Vaccines and Diagnostics, Inc. | Use of antagonistic anti-CD40 monoclonal antibodies |
| EP2243491A1 (en) | 2003-11-04 | 2010-10-27 | Novartis Vaccines and Diagnostics, Inc. | Use of antagonist anti-CD40 monoclonal antibodies for treatment of chronic lymphocytic leukemia |
| DK2163650T3 (en) | 2004-04-09 | 2015-11-02 | Genomic Health Inc | Genekspressionsmarkører for prediction of response to chemotherapy |
| WO2006044294A2 (en) | 2004-10-14 | 2006-04-27 | Eli Lilly And Company | Human protein c analogs |
| US8333970B2 (en) | 2005-05-18 | 2012-12-18 | Novartis Ag | Methods of monitoring the efficacy of anti-CD40 antibodies in treating a subject having an inflammatory or autoimmune disease |
| EP1894012A2 (en) * | 2005-05-18 | 2008-03-05 | Novartis AG | Methods for diagnosis and treatment of proliferative disorders mediated by cd40 signaling |
| CA2609269C (en) | 2005-05-26 | 2014-08-05 | Seattle Genetics, Inc. | Humanized anti-cd40 antibodies and their methods of use |
| US8278038B2 (en) | 2005-06-08 | 2012-10-02 | Millennium Pharmaceuticals, Inc. | Methods for the identification, assessment, and treatment of patients with cancer therapy |
| WO2007032743A2 (en) | 2005-09-16 | 2007-03-22 | Biovator Technologies Ab | In vitro assay for identification of allergenic proteins |
| DE102005052384B4 (de) | 2005-10-31 | 2009-09-24 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur Erkennung, Markierung und Behandlung von epithelialen Lungentumorzellen sowie Mittel zur Durchführung des Verfahrens |
| US7527774B2 (en) | 2005-12-22 | 2009-05-05 | Basf Catalysts Llc | Inlet metallic foam support coupled to precious metal catalyst for application on 4 stroke platforms |
| WO2007082379A2 (en) | 2006-01-20 | 2007-07-26 | Mcgill University | Method to identify cd40-sensitive cells using gene expression |
| US9353415B2 (en) | 2006-12-19 | 2016-05-31 | Thomson Reuters (Scientific) Llc | Methods for functional analysis of high-throughput experimental data and gene groups identified therefrom |
| US9617600B2 (en) | 2009-04-18 | 2017-04-11 | Genentech, Inc. | Methods for assessing responsiveness of B-cell lymphoma to treatment with anti-CD40 antibodies |
-
2008
- 2008-11-07 CA CA2704499A patent/CA2704499C/en active Active
- 2008-11-07 US US12/741,814 patent/US9068230B2/en active Active
- 2008-11-07 MX MX2010005080A patent/MX2010005080A/es active IP Right Grant
- 2008-11-07 AU AU2008323701A patent/AU2008323701B2/en active Active
- 2008-11-07 JP JP2010533308A patent/JP5730576B2/ja active Active
- 2008-11-07 CN CN200880124201.5A patent/CN101910414B/zh active Active
- 2008-11-07 EP EP08848388.8A patent/EP2222875B1/en active Active
- 2008-11-07 BR BRPI0820707-0A patent/BRPI0820707A2/pt not_active Application Discontinuation
- 2008-11-07 WO PCT/US2008/082920 patent/WO2009062125A1/en not_active Ceased
- 2008-11-07 KR KR1020107012374A patent/KR101620642B1/ko active Active
-
2010
- 2010-04-28 IL IL205391A patent/IL205391A/en active IP Right Grant
-
2013
- 2013-10-09 JP JP2013211645A patent/JP2014057588A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0820707A2 (pt) | 2015-06-16 |
| EP2222875A1 (en) | 2010-09-01 |
| JP2014057588A (ja) | 2014-04-03 |
| KR20100095564A (ko) | 2010-08-31 |
| EP2222875B1 (en) | 2014-08-20 |
| JP5730576B2 (ja) | 2015-06-10 |
| AU2008323701A1 (en) | 2009-05-14 |
| CA2704499C (en) | 2020-03-10 |
| AU2008323701B2 (en) | 2015-03-26 |
| CN101910414B (zh) | 2016-01-13 |
| CN101910414A (zh) | 2010-12-08 |
| US9068230B2 (en) | 2015-06-30 |
| JP2011504102A (ja) | 2011-02-03 |
| IL205391A (en) | 2015-08-31 |
| IL205391A0 (en) | 2010-12-30 |
| KR101620642B1 (ko) | 2016-05-12 |
| US20110104671A1 (en) | 2011-05-05 |
| CA2704499A1 (en) | 2009-05-14 |
| WO2009062125A1 (en) | 2009-05-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2010005080A (es) | Metodos y composiciones para determinar la sensibilidad de linfoma de celula b al tratamiento con anticuerpos anti-cd40. | |
| HUS2100051I1 (hu) | Kompozíciók és eljárások sejtproliferációs rendellenességek kezelésére | |
| PH12013502230A1 (en) | Multispecific antibodies | |
| JO3118B1 (ar) | تراكيب وطرق لبروتين c5 المتمم يستهدف الأجسام المضادة | |
| MX345909B (es) | Anticuerpos anti-fgfr3 y métodos que los utilizan. | |
| PT2203478E (pt) | Composições e métodos para uso de anticorpos contra esclerostina | |
| MX2009004532A (es) | Composiciones y metodos para unir esfingosina-1-fosfato. | |
| MY173526A (en) | Novel anti-?5?1 antibodies and uses thereof | |
| UA101478C2 (ru) | Соединения, полезные как ингибиторы raf-киназы | |
| CL2007003622A1 (es) | Anticuerpo monoclonal humano anti-cd19; composicion que lo comprende; y metodo de inhibicion del crecimiento de celulas tumorales. | |
| MX360301B (es) | Moleculas pequeñas que contienen boro como agentes antiinflamatorios. | |
| MX340555B (es) | Anticuerpos contra il-18r1 y usos de los mismos. | |
| MX2009008430A (es) | Anticuerpos anti-robo4 y sus usos. | |
| HUS1600044I1 (hu) | Eljárások mielóma multiplex kezelésére, anti-CS1 ellenanyagokon alapuló terápiák kombinációjának alkalmazásával | |
| WO2011097301A3 (en) | METHODS AND COMPOSITIONS FOR PREDICTING RESPONSIVENESS TO TREATMENT WITH TNF-α INHIBITOR | |
| TW200732349A (en) | Anti-OX40L antibodies and methods using same | |
| WO2008127290A3 (en) | Alginate and alginate lyase compositions and methods of use | |
| MY159553A (en) | Detection and treatment of pancreatic, ovarian and other cancers | |
| TW200640924A (en) | VEGF-R2 inhibitors and methods | |
| MA34598B1 (fr) | Procédés et compositions pour traiter le cancer du poumon | |
| MX336323B (es) | Anticuerpos de anti-poliubiquitina y metodos de uso. | |
| NZ579478A (en) | Epha3 antibodies for the treatment of solid tumors | |
| TW200738751A (en) | Anti-EphrinB2 antibodies and methods using same | |
| PH12013502194A1 (en) | Antibodies to egfl7 and methods for their use | |
| MX2012001999A (es) | Uso de inhibidores nkg2d para tratar enfermedades cardiovasculares y metabolicas, tal como diabetes tipo 2. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |