MX2010003656A - Sistema de administracion vaginal. - Google Patents
Sistema de administracion vaginal.Info
- Publication number
- MX2010003656A MX2010003656A MX2010003656A MX2010003656A MX2010003656A MX 2010003656 A MX2010003656 A MX 2010003656A MX 2010003656 A MX2010003656 A MX 2010003656A MX 2010003656 A MX2010003656 A MX 2010003656A MX 2010003656 A MX2010003656 A MX 2010003656A
- Authority
- MX
- Mexico
- Prior art keywords
- drospirenone
- membrane
- delivery system
- estrogen
- core
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invenci?n se refiere a un sistema de administraci?n intravaginal para la liberaci?n controlada de drospirenona y un estr?geno y, opcionalmente, tambi?n comprende una o m?s sustancias terap?uticamente activas o promotoras de la salud capaces de brindar y/o mejorar la protecci?n contra infecciones bacterianas y f?ngicas, y/o mejorar la protecci?n contra enfermedades de transmisi?n sexual. El sistema de administraci?n comprende uno o m?s compartimientos, cada uno de los cuales comprende un n?cleo y una membrana que recubre el n?cleo, dicho. n?cleo y dicha membrana est?n compuestos esencialmente por la misma composici?n de pol?mero o una composici?n de pol?mero diferente, donde al menos un compartimiento comprende drospirenona y al menos un compartimiento, que puede ser igual o diferente del que comprende drospirenona, comprende un estr?geno o una mezcla de drospirenona y un estr?geno, y donde la membrana o la superficie de la membrana o al menos uno de los n?cleos comprende dicha sustancia terap?uticamente activa o promotora de la salud.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07397042A EP2062568A1 (en) | 2007-11-22 | 2007-11-22 | Vaginal delivery system |
| EP07397043A EP2062569B1 (en) | 2007-11-22 | 2007-11-22 | Vaginal delivery system |
| PCT/FI2008/050670 WO2009066006A1 (en) | 2007-11-22 | 2008-11-19 | Vaginal delivery system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010003656A true MX2010003656A (es) | 2010-04-21 |
Family
ID=40394262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010003656A MX2010003656A (es) | 2007-11-22 | 2008-11-19 | Sistema de administracion vaginal. |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US20100285097A1 (es) |
| EP (1) | EP2227220A1 (es) |
| JP (1) | JP2011504484A (es) |
| KR (1) | KR20100090708A (es) |
| CN (1) | CN101873850A (es) |
| AR (1) | AR069379A1 (es) |
| AU (1) | AU2008327813A1 (es) |
| BR (1) | BRPI0815936A2 (es) |
| CA (1) | CA2705734A1 (es) |
| CL (1) | CL2008003421A1 (es) |
| CO (1) | CO6290642A2 (es) |
| CR (1) | CR11493A (es) |
| DO (1) | DOP2010000154A (es) |
| EA (1) | EA018112B1 (es) |
| EC (1) | ECSP10010104A (es) |
| IL (1) | IL205588A0 (es) |
| MX (1) | MX2010003656A (es) |
| NZ (1) | NZ584216A (es) |
| PA (1) | PA8805001A1 (es) |
| PE (1) | PE20091025A1 (es) |
| SG (1) | SG186002A1 (es) |
| SV (1) | SV2010003513A (es) |
| TW (1) | TW200927141A (es) |
| UY (1) | UY31475A1 (es) |
| WO (1) | WO2009066006A1 (es) |
| ZA (1) | ZA201002122B (es) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI121000B (fi) * | 2008-11-19 | 2010-06-15 | Bayer Schering Pharma Oy | Intravaginaalinen antojärjestelmä ja menetelmä sen valmistamiseksi |
| US8815971B2 (en) | 2008-12-22 | 2014-08-26 | ATRP Solutions, Inc. | Control over controlled radical polymerization processes |
| US8822610B2 (en) | 2008-12-22 | 2014-09-02 | ATRP Solutions, Inc. | Control over controlled radical polymerization processes |
| WO2010123574A1 (en) | 2009-04-23 | 2010-10-28 | Atrp Solutions Inc | Star macromolecules for personal and home care |
| US9783628B2 (en) | 2009-04-23 | 2017-10-10 | ATRP Solutions, Inc. | Dual-mechanism thickening agents for hydraulic fracturing fluids |
| US8173750B2 (en) | 2009-04-23 | 2012-05-08 | ATRP Solutions, Inc. | Star macromolecules for personal and home care |
| FI20095550A0 (fi) * | 2009-05-19 | 2009-05-19 | Bayer Schering Pharma Oy | Vaginaalinen antojärjestelmä |
| FI20095563L (fi) * | 2009-05-20 | 2010-11-21 | Bayer Schering Pharma Oy | Vaginaalinen antojärjestelmä |
| AU2011238710B2 (en) * | 2010-03-28 | 2015-08-20 | Evestra, Inc. | Intravaginal drug delivery device |
| DE102010003494A1 (de) * | 2010-03-31 | 2011-10-06 | Bayer Schering Pharma Aktiengesellschaft | Parenterales Abgabesystem, das Aromatasehemmer und Gestagene freisetzt, für die Behandlung von Endometriose |
| CA2803874A1 (en) * | 2010-06-22 | 2011-12-29 | Anu Mahashabde | Intravaginal devices comprising anticholinergic agents, and methods of making thereof |
| US8580294B2 (en) | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
| US9078813B2 (en) | 2010-11-12 | 2015-07-14 | The University Of Utah Research Foundation | Intravaginal devices for controlled delivery of lubricants |
| WO2012073924A1 (ja) * | 2010-11-29 | 2012-06-07 | 株式会社明治 | 子宮内膜症の予防及び/又は改善剤及びこれを含んでなる飲食品組成物 |
| US9587064B2 (en) | 2010-12-08 | 2017-03-07 | ATRP Solutions, Inc. | Salt-tolerant star macromolecules |
| KR101263916B1 (ko) | 2011-01-11 | 2013-05-13 | 이장희 | 성 호르몬 방출 장치 및 이를 이용한 동물 피임 및 발정 유도 방법 |
| US9937335B2 (en) * | 2011-06-06 | 2018-04-10 | Oak Crest Institute Of Science | Drug delivery device employing wicking release window |
| EP2731587B1 (en) * | 2011-07-15 | 2024-12-04 | Universiteit Gent | Intravaginal delivery system |
| KR20140074281A (ko) * | 2011-07-20 | 2014-06-17 | 패트릭 에프. 카이저 | 약물 전달용 질내 장치 |
| EP2749286B1 (en) | 2011-08-26 | 2017-03-01 | Universidad De Santiago De Chile | Use of non-steroidal anti-inflammatory drugs meloxicam and piroxicam, administered intravaginally, for interruption of a woman's ovulation process |
| CN103007427B (zh) * | 2011-09-21 | 2016-01-20 | 上海市计划生育科学研究所 | 缓控释宫内释药器及其制备方法 |
| TWI615155B (zh) * | 2011-11-01 | 2018-02-21 | 拜耳股份有限公司 | 滲透活性的陰道遞送系統 |
| AR089765A1 (es) | 2012-01-23 | 2014-09-17 | Bayer Oy | Un sistema para el suministro de un farmaco |
| EP2852595B1 (en) | 2012-05-21 | 2016-06-22 | Bayer Pharma Aktiengesellschaft | Substituted benzothienopyrimidines |
| HK1208809A1 (en) | 2012-06-13 | 2016-03-18 | 伊沃菲姆股份有限公司 | Compositions and methods for enhancing the efficacy of contraceptive microbicides |
| JP6294885B2 (ja) | 2012-08-30 | 2018-03-14 | エーティーアールピー ソリューションズ インコーポレイテッドATRP Solutions,Inc. | 星形高分子、星形高分子組成物および星形高分子の製造方法 |
| PT2893804T (pt) | 2012-09-03 | 2018-06-26 | Ecosea Farming S A | Sistema de imersão de um reservatório-jaula destinado à cultura e/ou contenção de espécies hidrobiológicas |
| TW201412740A (zh) | 2012-09-20 | 2014-04-01 | Bayer Pharma AG | 經取代之吡咯并嘧啶胺基苯并噻唑酮 |
| WO2014066480A1 (en) * | 2012-10-23 | 2014-05-01 | Estech Usa, Llc | Treating conditions caused by abnormal growth of pathogens in body cavities |
| EP2951220B1 (en) | 2013-02-04 | 2020-11-25 | Pilot Polymer Technologies, Inc. | Salt-tolerant star macromolecules |
| SE539540C2 (sv) * | 2013-09-12 | 2017-10-10 | Qpharma Ab | Ett läkemedelsavgivningssystem för en eller flera aktiva beståndsdelar |
| BR112016010103A8 (pt) * | 2013-11-05 | 2018-01-30 | Taris Biomedical Llc | métodos, kits e dispositivos de suprimento de fármaco osmótico. |
| US10137031B2 (en) | 2013-11-14 | 2018-11-27 | International Partnership For Microbicides, Inc. | Combination therapy intravaginal rings |
| US10413504B2 (en) * | 2013-12-11 | 2019-09-17 | Merck Sharp & Dohme Corp. | Intravaginal ring drug delivery system |
| KR102407408B1 (ko) | 2013-12-19 | 2022-06-10 | 에보펨 인코포레이티드 | 알긴산계 항균성 화합물을 사용하는 염증 및 질병을 억제하기 위한 조성물 및 방법 |
| PT3125964T (pt) * | 2014-04-01 | 2024-09-09 | Poly Med Inc | Contracetivo e dispositivo relacionado |
| JP6689210B2 (ja) | 2014-07-03 | 2020-04-28 | パイロット ポリマー テクノロジーズ, インク. | 界面活性剤相溶性星形高分子 |
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| CN104117135A (zh) * | 2014-08-11 | 2014-10-29 | 崔仁海 | 阴道内植入式治疗装置 |
| CN104558491A (zh) * | 2014-12-25 | 2015-04-29 | 中南大学 | 能促进组织内膜生长的聚氨酯材料的制备方法 |
| US11096888B2 (en) * | 2015-05-13 | 2021-08-24 | Bayer Oy | Long acting drug delivery device and its use in contraception |
| EP3344749A1 (en) * | 2015-08-31 | 2018-07-11 | Chr. Hansen A/S | Lactobacillus fermentum bacteria with antifungal activity |
| PE20181214A1 (es) * | 2015-12-21 | 2018-07-24 | Bayer Oy | Metodo para fabricar un dispositivo para la administracion de farmacos y un dispositivo para la administracion de farmacos fabricado segun el metodo |
| CA3008940A1 (en) * | 2015-12-21 | 2017-06-29 | Bayer Oy | A method of manufacturing a vaginal ring |
| CA3009697C (en) * | 2016-01-04 | 2024-05-28 | Jurox Pty Ltd | Drug release device and use |
| KR101720145B1 (ko) * | 2016-07-08 | 2017-04-07 | (주)정가진면역연구소 | 여성 질염 예방 및 개선 기능성 조성물 |
| EP3522879A4 (en) | 2016-10-04 | 2020-06-03 | Evofem, Inc. | Method of treatment and prevention of bacterial vaginosis |
| PE20211195A1 (es) * | 2017-09-27 | 2021-07-01 | Bayer Oy | Un metodo para modificar la liberacion de un agente terapeuticamente activo de una matriz elastomerica |
| MX2020011321A (es) * | 2018-04-27 | 2021-02-09 | Evestra Inc | Profármacos de estrógeno y métodos de administración de profármacos de estrógeno. |
| JP2021524841A (ja) | 2018-05-24 | 2021-09-16 | セラニーズ・イーブイエイ・パフォーマンス・ポリマーズ・エルエルシー | 高分子薬剤化合物の持続放出用の埋め込み型デバイス |
| AU2019275409B2 (en) | 2018-05-24 | 2024-08-15 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
| WO2019222856A1 (en) | 2018-05-24 | 2019-11-28 | Nureva Inc. | Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones |
| WO2020007780A1 (en) * | 2018-07-02 | 2020-01-09 | Artpred B.V. | Method and kit for altering the outcome of an assisted reproductive technology procedure |
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| CN110585246B (zh) * | 2019-09-22 | 2020-06-02 | 深圳市多微生保健食品有限公司 | 一种阴道抑菌制剂及其制备方法 |
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| IT202000029267A1 (it) * | 2020-12-01 | 2022-06-01 | Francesca FRIZZI | Dispositivo vaginale |
| EP4329734A4 (en) | 2021-04-26 | 2025-04-02 | Celanese EVA Performance Polymers LLC | Implantable device for the delayed release of a macromolecular drug compound |
| EP4215181A1 (en) * | 2022-01-21 | 2023-07-26 | Sever Pharma Solutions | An intravaginal ring |
| US20250248928A1 (en) * | 2022-04-14 | 2025-08-07 | Yale University | Nanoparticles and nanoparticle-releasing vaginal rings |
| CA3259928A1 (en) * | 2022-08-01 | 2024-02-08 | Lupin Inc. | DRUG DELIVERY SYSTEM FOR ULTRA-LOW DOSE ESTROGEN COMBINATIONS AND METHODS AND USES THEREOF |
| WO2025233917A1 (en) * | 2024-05-10 | 2025-11-13 | Millicent Pharma Limited | A vaginal system containing a core, and methods of manufacture and use thereof |
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| IL48277A (en) * | 1974-10-18 | 1978-03-10 | Schering Ag | Vaginal ring |
| US4237885A (en) * | 1978-10-23 | 1980-12-09 | Alza Corporation | Delivery system with mated members for storing and releasing a plurality of beneficial agents |
| DE3040978A1 (de) * | 1980-10-28 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Vaginalring |
| EP0180264A1 (en) * | 1984-10-12 | 1986-05-07 | Akzo N.V. | Release system for two or more active substances |
| FR2618329B1 (fr) * | 1987-07-22 | 1997-03-28 | Dow Corning Sa | Procede de fabrication d'un anneau capable d'assurer la liberation d'un agent therapeutique, et anneau fabrique par ce procede |
| FI95768C (fi) * | 1993-06-17 | 1996-03-25 | Leiras Oy | Emättimensisäinen antosysteemi |
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| US5972372A (en) * | 1996-07-31 | 1999-10-26 | The Population Council, Inc. | Intravaginal rings with insertable drug-containing core |
| DE19651000A1 (de) * | 1996-12-01 | 1998-06-04 | Schering Ag | Oxyiminopregnancarbolactone |
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| US20040247574A1 (en) * | 2003-05-27 | 2004-12-09 | Christopherson Kent W. | Methods for enhancing stem cell engraftment during transplantation |
| WO2005027807A1 (en) * | 2003-09-19 | 2005-03-31 | Drugtech Corporation | Pharmaceutical delivery system |
| TWI290837B (en) * | 2004-03-24 | 2007-12-11 | Organon Nv | Drug delivery system |
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| US20090181075A1 (en) * | 2005-07-15 | 2009-07-16 | Gordon Ryan D | Drospirenone containing transdermal drug delivery devices and methods of delivery thereof |
-
2008
- 2008-10-22 TW TW097140414A patent/TW200927141A/zh unknown
- 2008-11-17 UY UY31475A patent/UY31475A1/es not_active Application Discontinuation
- 2008-11-18 CL CL2008003421A patent/CL2008003421A1/es unknown
- 2008-11-19 NZ NZ584216A patent/NZ584216A/en not_active IP Right Cessation
- 2008-11-19 AU AU2008327813A patent/AU2008327813A1/en not_active Abandoned
- 2008-11-19 CA CA2705734A patent/CA2705734A1/en not_active Abandoned
- 2008-11-19 JP JP2010534512A patent/JP2011504484A/ja active Pending
- 2008-11-19 BR BRPI0815936A patent/BRPI0815936A2/pt not_active IP Right Cessation
- 2008-11-19 EA EA201070639A patent/EA018112B1/ru not_active IP Right Cessation
- 2008-11-19 KR KR1020107013858A patent/KR20100090708A/ko not_active Withdrawn
- 2008-11-19 PE PE2008001954A patent/PE20091025A1/es not_active Application Discontinuation
- 2008-11-19 CN CN200880117430A patent/CN101873850A/zh active Pending
- 2008-11-19 MX MX2010003656A patent/MX2010003656A/es active IP Right Grant
- 2008-11-19 EP EP08852534A patent/EP2227220A1/en not_active Withdrawn
- 2008-11-19 SG SG2012084059A patent/SG186002A1/en unknown
- 2008-11-19 WO PCT/FI2008/050670 patent/WO2009066006A1/en not_active Ceased
- 2008-11-19 US US12/744,227 patent/US20100285097A1/en not_active Abandoned
- 2008-11-20 AR ARP080105040A patent/AR069379A1/es not_active Application Discontinuation
- 2008-11-20 US US12/275,115 patent/US20090142313A1/en not_active Abandoned
- 2008-11-21 PA PA20088805001A patent/PA8805001A1/es unknown
-
2010
- 2010-03-22 SV SV2010003513A patent/SV2010003513A/es unknown
- 2010-03-25 ZA ZA2010/02122A patent/ZA201002122B/en unknown
- 2010-04-14 EC EC2010010104A patent/ECSP10010104A/es unknown
- 2010-05-06 IL IL205588A patent/IL205588A0/en unknown
- 2010-05-21 DO DO2010000154A patent/DOP2010000154A/es unknown
- 2010-06-14 CR CR11493A patent/CR11493A/es not_active Application Discontinuation
- 2010-06-22 CO CO10074973A patent/CO6290642A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CL2008003421A1 (es) | 2009-08-07 |
| EA018112B1 (ru) | 2013-05-30 |
| SG186002A1 (en) | 2012-12-28 |
| JP2011504484A (ja) | 2011-02-10 |
| US20090142313A1 (en) | 2009-06-04 |
| KR20100090708A (ko) | 2010-08-16 |
| PE20091025A1 (es) | 2009-08-17 |
| PA8805001A1 (es) | 2009-06-23 |
| ECSP10010104A (es) | 2010-06-29 |
| UY31475A1 (es) | 2009-07-17 |
| EP2227220A1 (en) | 2010-09-15 |
| CA2705734A1 (en) | 2009-05-28 |
| CO6290642A2 (es) | 2011-06-20 |
| CN101873850A (zh) | 2010-10-27 |
| WO2009066006A1 (en) | 2009-05-28 |
| SV2010003513A (es) | 2010-08-09 |
| US20100285097A1 (en) | 2010-11-11 |
| TW200927141A (en) | 2009-07-01 |
| NZ584216A (en) | 2012-03-30 |
| AU2008327813A1 (en) | 2009-05-28 |
| DOP2010000154A (es) | 2010-07-31 |
| ZA201002122B (en) | 2011-06-29 |
| IL205588A0 (en) | 2010-11-30 |
| BRPI0815936A2 (pt) | 2019-08-27 |
| EA201070639A1 (ru) | 2010-10-29 |
| CR11493A (es) | 2010-08-23 |
| AR069379A1 (es) | 2010-01-20 |
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