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MX2010000525A - Particulas similares al virus de la influenza (vlps) que comprenden hemaglutinina producida dentro de una planta. - Google Patents

Particulas similares al virus de la influenza (vlps) que comprenden hemaglutinina producida dentro de una planta.

Info

Publication number
MX2010000525A
MX2010000525A MX2010000525A MX2010000525A MX2010000525A MX 2010000525 A MX2010000525 A MX 2010000525A MX 2010000525 A MX2010000525 A MX 2010000525A MX 2010000525 A MX2010000525 A MX 2010000525A MX 2010000525 A MX2010000525 A MX 2010000525A
Authority
MX
Mexico
Prior art keywords
vlps
plant
influenza
particles
influenza virus
Prior art date
Application number
MX2010000525A
Other languages
English (en)
Inventor
Marc-Andr D Aoust
Louis-Philippe Vezina
Manon Couture
Fr D Ric Ors
Sonia Trepanier
Pierre-Olivier Lavoie
Michele Dargis
Nathalie Landry
Original Assignee
Medicago Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicago Inc filed Critical Medicago Inc
Publication of MX2010000525A publication Critical patent/MX2010000525A/es

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    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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Abstract

Se proporciona un m?todo para sintetizar part?culas similares al virus de la influenza (VLPs) dentro de una planta o una porci?n de una planta. El m?todo involucra la expresi?n de influenza HA en plantas y la purificaci?n mediante cromatograf?a de exclusi?n de tama?o. La invenci?n se enfoca tambi?n a una VLP que comprende prote?na de influenza HA y l?pidos vegetales. La invenci?n se enfoca tambi?n a un ?cido nucleico que codifica influenza HA, as? como vectores. Las VLPs pueden utilizarse para formular vacunas contra la influenza o pueden utilizarse para enriquecer vacunas existentes.
MX2010000525A 2007-07-13 2008-07-11 Particulas similares al virus de la influenza (vlps) que comprenden hemaglutinina producida dentro de una planta. MX2010000525A (es)

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US95941407P 2007-07-13 2007-07-13
US99060307P 2007-11-27 2007-11-27
US1327207P 2007-12-12 2007-12-12
CA002615372A CA2615372A1 (en) 2007-07-13 2008-01-21 Influenza virus-like particles (vlps) comprising hemagglutinin
US2277508P 2008-01-22 2008-01-22
PCT/CA2008/001281 WO2009009876A1 (en) 2007-07-13 2008-07-11 Influenza virus-like particles (vlps) comprising hemagglutinin produced within a plant

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