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MX2009011601A - Agentes terapeuticos utiles para tratar el dolor. - Google Patents

Agentes terapeuticos utiles para tratar el dolor.

Info

Publication number
MX2009011601A
MX2009011601A MX2009011601A MX2009011601A MX2009011601A MX 2009011601 A MX2009011601 A MX 2009011601A MX 2009011601 A MX2009011601 A MX 2009011601A MX 2009011601 A MX2009011601 A MX 2009011601A MX 2009011601 A MX2009011601 A MX 2009011601A
Authority
MX
Mexico
Prior art keywords
therapeutic agents
pharmaceutically acceptable
agents useful
treating pain
formulae
Prior art date
Application number
MX2009011601A
Other languages
English (en)
Inventor
Tafesse Laykea
Original Assignee
Purdue Pharma Lp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Pharma Lp filed Critical Purdue Pharma Lp
Publication of MX2009011601A publication Critical patent/MX2009011601A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

En la presente se divulga un compuesto de Fórmula: o un derivado farmacéuticamente aceptable del mismo, donde Ar1, Ar2, X, R3, y m son según se divulga en la presente. Los compuestos de las Fórmulas (I)-(V) y los derivados farmacéuticamente aceptables de los mismos; las composiciones que comprenden una cantidad efectiva de un compuesto de Fórmulas (I)-(V) o un derivado farmacéuticamente aceptable del mismo; y métodos para tratar o prevenir el dolor, UI, úlcera, IBD, o lBS en un animal que comprende administrar a un animal con necesidad del mismo una cantidad efectiva de un compuesto de Fórmulas (I)-(V) o un derivado farmacéuticamente aceptable del mismo.
MX2009011601A 2007-04-27 2008-04-25 Agentes terapeuticos utiles para tratar el dolor. MX2009011601A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92405607P 2007-04-27 2007-04-27
US92437707P 2007-05-11 2007-05-11
PCT/US2008/005329 WO2008133973A1 (en) 2007-04-27 2008-04-25 Therapeutic agents useful for treating pain

Publications (1)

Publication Number Publication Date
MX2009011601A true MX2009011601A (es) 2009-11-10

Family

ID=39595655

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009011601A MX2009011601A (es) 2007-04-27 2008-04-25 Agentes terapeuticos utiles para tratar el dolor.

Country Status (10)

Country Link
US (1) US8389549B2 (es)
EP (2) EP2479173A1 (es)
JP (1) JP5372913B2 (es)
KR (1) KR20090130422A (es)
AU (1) AU2008246202B2 (es)
CA (1) CA2685121A1 (es)
IL (1) IL201422A0 (es)
MX (1) MX2009011601A (es)
NZ (1) NZ579820A (es)
WO (1) WO2008133973A1 (es)

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CN102030771B (zh) 2009-09-30 2013-07-17 孙群 作为trpv1阻断剂的化合物、药物组合物及其医药用途
JP5876423B2 (ja) 2010-06-22 2016-03-02 塩野義製薬株式会社 Ｔｒｐｖ１阻害活性を有する化合物とその使用
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KR101589837B1 (ko) 2011-06-22 2016-01-29 퍼듀 퍼머 엘피 디히드록시 치환기를 포함하는 trpv1 길항제 및 그의 용도
US9394293B2 (en) 2011-08-10 2016-07-19 Purdue Pharma L.P. TRPV1 antagonists including dihydroxy substituent and uses thereof
US9962452B2 (en) 2013-02-04 2018-05-08 Zhuhai Beihai Biotech Co., Ltd. Soluble complexes of drug analogs and albumin
EP3049082B1 (en) * 2013-09-24 2019-05-22 Purdue Pharma L.P. Treatment of burn pain by trpv1 modulators
US9937259B2 (en) 2014-06-27 2018-04-10 Zhuhai Beihai Biotech Co., Ltd. Abiraterone derivatives and non-covalent complexes with albumin
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Also Published As

Publication number Publication date
EP2091936A1 (en) 2009-08-26
EP2091936B1 (en) 2013-05-15
JP5372913B2 (ja) 2013-12-18
US20100130552A1 (en) 2010-05-27
JP2010525064A (ja) 2010-07-22
WO2008133973A1 (en) 2008-11-06
EP2479173A1 (en) 2012-07-25
KR20090130422A (ko) 2009-12-23
AU2008246202B2 (en) 2011-12-01
AU2008246202A1 (en) 2008-11-06
NZ579820A (en) 2011-01-28
CA2685121A1 (en) 2008-11-06
IL201422A0 (en) 2010-05-31
US8389549B2 (en) 2013-03-05

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