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MX2009005712A - Antagonistas de receptor de orexina de diazepam sustituido. - Google Patents

Antagonistas de receptor de orexina de diazepam sustituido.

Info

Publication number
MX2009005712A
MX2009005712A MX2009005712A MX2009005712A MX2009005712A MX 2009005712 A MX2009005712 A MX 2009005712A MX 2009005712 A MX2009005712 A MX 2009005712A MX 2009005712 A MX2009005712 A MX 2009005712A MX 2009005712 A MX2009005712 A MX 2009005712A
Authority
MX
Mexico
Prior art keywords
compounds
receptor antagonists
orexin receptor
substituted diazepan
substituted
Prior art date
Application number
MX2009005712A
Other languages
English (en)
Inventor
Paul J Coleman
Michael J Breslin
Jeffrey M Bergman
Christopher D Cox
Swati P Mercer
Anthony J Roecker
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39284173&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009005712(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of MX2009005712A publication Critical patent/MX2009005712A/es

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    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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Abstract

La presente invención está dirigida a compuestos de diazepam sustituidos que son antagonistas de receptores de orexina, y que son útiles en el tratamiento o la prevención de trastornos o enfermedades neurológicos y psiquiátricos en los que están implicados los receptores de orexina. La invención está también dirigida a composiciones farmacéuticas que comprenden estos compuestos y al uso de estos compuestos y composiciones en la prevención o el tratamiento de dichas enfermedades en las que están implicados receptores de orexina.
MX2009005712A 2006-12-01 2007-11-30 Antagonistas de receptor de orexina de diazepam sustituido. MX2009005712A (es)

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PCT/US2007/024690 WO2008069997A1 (en) 2006-12-01 2007-11-30 Substituted diazepan compounds as orexin receptor antagonists

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