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MX2007014616A - Inhibidores de señalizacion del receptor del factor a de crecimiento endotelial vascular y del receptor del factor de crecimiento de hepatocitos. - Google Patents

Inhibidores de señalizacion del receptor del factor a de crecimiento endotelial vascular y del receptor del factor de crecimiento de hepatocitos.

Info

Publication number
MX2007014616A
MX2007014616A MX2007014616A MX2007014616A MX2007014616A MX 2007014616 A MX2007014616 A MX 2007014616A MX 2007014616 A MX2007014616 A MX 2007014616A MX 2007014616 A MX2007014616 A MX 2007014616A MX 2007014616 A MX2007014616 A MX 2007014616A
Authority
MX
Mexico
Prior art keywords
receptor signaling
receptor
hgf
inhibitors
signaling
Prior art date
Application number
MX2007014616A
Other languages
English (en)
Inventor
Oscar Mario Saavedra
Lijie Zhan
Stephen William Claridge
Franck Raeppel
Arkadii Vaisburg
Raeppel Stephane
Deziel Robert
Mannion Michael
Zhou Nancy
Gaudette Frederic
Lljubomir Isakovic
Amal Wahhab
Marie-Claude Granger
Bernstein Naomy
Original Assignee
Methylgene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Methylgene Inc filed Critical Methylgene Inc
Publication of MX2007014616A publication Critical patent/MX2007014616A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Esta invención se refiere a la inhibición de señalización de receptor VEGF y señalización del receptor HGF; la invención provee compuestos y métodos para inhibir la señalización del receptor VEGF y la señalización del receptor HGF; la invención también provee composiciones y métodos para tratar enfermedades y condiciones proliferativas celulares.
MX2007014616A 2005-05-20 2006-05-19 Inhibidores de señalizacion del receptor del factor a de crecimiento endotelial vascular y del receptor del factor de crecimiento de hepatocitos. MX2007014616A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US68303605P 2005-05-20 2005-05-20
US75490205P 2005-12-29 2005-12-29
US78505406P 2006-03-22 2006-03-22
PCT/IB2006/004306 WO2008041053A2 (en) 2005-05-20 2006-05-19 Inhibitors of vegf receptor and hgf receptor signaling

Publications (1)

Publication Number Publication Date
MX2007014616A true MX2007014616A (es) 2009-08-12

Family

ID=39190471

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007014616A MX2007014616A (es) 2005-05-20 2006-05-19 Inhibidores de señalizacion del receptor del factor a de crecimiento endotelial vascular y del receptor del factor de crecimiento de hepatocitos.

Country Status (13)

Country Link
US (2) US8093264B2 (es)
EP (1) EP1957498B1 (es)
JP (1) JP5148499B2 (es)
KR (1) KR101378716B1 (es)
CN (1) CN101796055B (es)
AU (1) AU2006343808B2 (es)
BR (1) BRPI0610322B8 (es)
CA (1) CA2611370C (es)
ES (1) ES2623221T3 (es)
IL (1) IL187484A (es)
MX (1) MX2007014616A (es)
NZ (1) NZ564283A (es)
WO (1) WO2008041053A2 (es)

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Also Published As

Publication number Publication date
CA2611370C (en) 2014-11-25
BRPI0610322A2 (pt) 2010-06-15
AU2006343808B2 (en) 2012-03-29
EP1957498B1 (en) 2017-02-15
BRPI0610322B8 (pt) 2021-05-25
IL187484A (en) 2014-04-30
WO2008041053A2 (en) 2008-04-10
US20120083482A1 (en) 2012-04-05
ES2623221T3 (es) 2017-07-10
JP5148499B2 (ja) 2013-02-20
CA2611370A1 (en) 2006-11-20
CN101796055B (zh) 2013-09-04
BRPI0610322B1 (pt) 2020-12-01
JP2009504804A (ja) 2009-02-05
US8093264B2 (en) 2012-01-10
WO2008041053A3 (en) 2009-12-23
US8329726B2 (en) 2012-12-11
US20070004675A1 (en) 2007-01-04
EP1957498A2 (en) 2008-08-20
NZ564283A (en) 2011-07-29
AU2006343808A1 (en) 2008-04-10
EP1957498A4 (en) 2010-10-27
KR20080059112A (ko) 2008-06-26
KR101378716B1 (ko) 2014-04-10
IL187484A0 (en) 2011-08-01
CN101796055A (zh) 2010-08-04

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