MX2007005403A - Sistema de capsulas blandas que no contienen gelatina. - Google Patents
Sistema de capsulas blandas que no contienen gelatina.Info
- Publication number
- MX2007005403A MX2007005403A MX2007005403A MX2007005403A MX2007005403A MX 2007005403 A MX2007005403 A MX 2007005403A MX 2007005403 A MX2007005403 A MX 2007005403A MX 2007005403 A MX2007005403 A MX 2007005403A MX 2007005403 A MX2007005403 A MX 2007005403A
- Authority
- MX
- Mexico
- Prior art keywords
- fills
- alkaline
- carrier
- active ingredients
- gelatin
- Prior art date
Links
- 229920000159 gelatin Polymers 0.000 title abstract 2
- 239000008273 gelatin Substances 0.000 title abstract 2
- 239000007901 soft capsule Substances 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 238000005538 encapsulation Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 108010010803 Gelatin Proteins 0.000 abstract 1
- 229920002472 Starch Polymers 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 235000010418 carrageenan Nutrition 0.000 abstract 1
- 229920001525 carrageenan Polymers 0.000 abstract 1
- 229940113118 carrageenan Drugs 0.000 abstract 1
- 239000000679 carrageenan Substances 0.000 abstract 1
- 239000007903 gelatin capsule Substances 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 235000019698 starch Nutrition 0.000 abstract 1
- 239000008107 starch Substances 0.000 abstract 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
La presente invencion se refiere a un sistema de encapsulacion sin gelatina para capsulas blandas rellenas con liquido, que por la naturaleza del portador, el equilibrio cationico-ionico del portador y de los ingredientes activos, o de la concentracion de los ingredientes activos y los excipientes, son diferentes o imposibles de encapsular comercialmente en capsulas de gelatina. En particular, el sistema esta adaptado para la encapsulacion de rellenos altamente basicos, o alcalinos. El sistema proporciona predominantemente una capa externa a base de almidon y de carragenina gelificante, que exhibe una alta resistencia tanto a los rellenos concentrados como a los rellenos alcalinos, en particular, a aquellos rellenos que contienen la sal o las sales de bases fuertes y de acidos debiles.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/984,205 US8231896B2 (en) | 2004-11-08 | 2004-11-08 | Non-gelatin soft capsule system |
| PCT/US2005/038532 WO2006052452A1 (en) | 2004-11-08 | 2005-10-26 | Non-gelatin soft capsule system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007005403A true MX2007005403A (es) | 2007-05-16 |
Family
ID=36316590
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007005403A MX2007005403A (es) | 2004-11-08 | 2005-10-26 | Sistema de capsulas blandas que no contienen gelatina. |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US8231896B2 (es) |
| EP (2) | EP2289496B1 (es) |
| JP (1) | JP5192816B2 (es) |
| AR (1) | AR051237A1 (es) |
| AT (1) | ATE536866T1 (es) |
| AU (1) | AU2005305232B2 (es) |
| BR (1) | BRPI0517674B8 (es) |
| CA (1) | CA2585721C (es) |
| CY (1) | CY1112518T1 (es) |
| DK (1) | DK1809261T3 (es) |
| ES (2) | ES2603225T3 (es) |
| MX (1) | MX2007005403A (es) |
| PE (1) | PE20061136A1 (es) |
| PL (1) | PL1809261T3 (es) |
| PT (1) | PT1809261E (es) |
| SI (1) | SI1809261T1 (es) |
| TW (1) | TWI405592B (es) |
| UY (1) | UY29200A1 (es) |
| WO (1) | WO2006052452A1 (es) |
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| CA2529984C (en) | 2003-06-26 | 2012-09-25 | Isa Odidi | Oral multi-functional pharmaceutical capsule preparations of proton pump inhibitors |
| US8394409B2 (en) * | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
| US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
| US20070053868A1 (en) * | 2005-03-08 | 2007-03-08 | Banner Pharmacaps, Inc. | Solvent system for enhancing the solubility of pharmaceutical agents |
| US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
| PT3095447T (pt) | 2006-02-03 | 2022-01-24 | Opko Renal Llc | Tratamento da insuficiência e deficiência de vitamina d com 25-hidroxivitamina d2 e 25-hidroxivitamina d3 |
| CA2648280C (en) * | 2006-04-03 | 2014-03-11 | Isa Odidi | Controlled release delivery device comprising an organosol coat |
| US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
| SI2037936T1 (sl) | 2006-06-21 | 2014-11-28 | Opko Renal, Llc | Postopek zdravljenja in prepreäśevanja sekundarnega hiperparatiroidizma |
| JP5021263B2 (ja) * | 2006-10-02 | 2012-09-05 | 中日本カプセル 株式会社 | 皮膜用組成物 |
| SI2481400T1 (sl) | 2007-04-25 | 2014-11-28 | Opko IP Holdings II, Inc. | Nadzorovano oralno sproščanje sestavkov, ki vsebujejo spojino vitamina D in voskasti nosilec |
| EP3225243B1 (en) | 2007-04-25 | 2025-09-03 | Opko Renal, LLC | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
| EP2148684B1 (en) | 2007-04-25 | 2013-01-16 | Cytochroma Inc. | Method of treating vitamin d insufficiency and deficiency |
| US20090004231A1 (en) * | 2007-06-30 | 2009-01-01 | Popp Shane M | Pharmaceutical dosage forms fabricated with nanomaterials for quality monitoring |
| AU2007362356A1 (en) * | 2007-12-12 | 2009-06-18 | Northern Innovations And Formulations Corp. | Particles in a capsule |
| GB0801643D0 (en) * | 2008-01-29 | 2008-03-05 | Probio Nutraceuticals As | Product |
| ES2593356T3 (es) | 2008-04-02 | 2016-12-07 | Opko Ireland Global Holdings, Ltd. | Métodos, composiciones, usos y kits útiles para la deficiencia de la vitamina D y trastornos relacionados |
| JP5696150B2 (ja) | 2009-09-10 | 2015-04-08 | エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ | 高い強度を有するシームレスなアルギン酸塩カプセル |
| LT2552484T (lt) | 2010-03-29 | 2020-04-27 | Opko Ireland Global Holdings, Ltd. | Būdai ir kompozicijos, skirti paratiroidų lygiams sumažinti |
| BR112013002721B8 (pt) * | 2010-08-04 | 2021-05-25 | Scherer Technologies Llc R P | composição formadora de filme para cápsulas moles, cápsulas moles e seu invólucro |
| US8992971B2 (en) | 2011-04-20 | 2015-03-31 | Suheung Capsule Co., Ltd. | Non-animal soft capsule shell composition having improved disintegration and shell hardness |
| KR101411364B1 (ko) * | 2012-03-16 | 2014-06-30 | 주식회사 서흥 | 전분을 주기재로 사용한 연질 캡슐 피막 조성물 |
| KR101178842B1 (ko) * | 2011-04-20 | 2012-09-03 | 주식회사 서흥캅셀 | 붕해도 및 피막 경도를 개선한 비동물성 연질 캡슐 피막 조성물 |
| KR101294614B1 (ko) | 2012-03-16 | 2013-08-08 | 주식회사 서흥캅셀 | 타피오카 변성전분을 주기재로 사용한 연질 캡슐 피막 조성물 |
| KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 ｄ 방출 제형 |
| EP2968081A4 (en) * | 2013-03-15 | 2016-08-10 | Banner Life Sciences Llc | MOLLE ENTERIC CAPSULES NOT CONTAINING GELATIN |
| KR101445334B1 (ko) * | 2013-06-05 | 2014-10-01 | 코스맥스바이오 주식회사 | 화학적 금속염을 포함하지 않는 식물성 연질캡슐조성물 |
| JP5769760B2 (ja) * | 2013-06-25 | 2015-08-26 | アール．ピー． シェーラー テクノロジーズ エルエルシー | ソフトカプセル用シェル形成組成物及びソフトカプセル |
| US20150010622A1 (en) * | 2013-07-03 | 2015-01-08 | R.P. Scherer Technologies, Llc | Capsule formulation comprising fexofenadine |
| WO2015059864A1 (ja) * | 2013-10-25 | 2015-04-30 | コニカミノルタ株式会社 | 粒子状肥料およびその製造方法 |
| CN103520133B (zh) * | 2013-10-26 | 2015-02-04 | 中山市凯博思淀粉材料科技有限公司 | 一种淀粉基软胶囊的制备方法 |
| CN103495176B (zh) * | 2013-10-26 | 2015-01-28 | 中山市凯博思淀粉材料科技有限公司 | 一种共混挤出法制备淀粉基软胶囊的方法 |
| CN103550065B (zh) * | 2013-10-26 | 2015-01-28 | 中山市凯博思淀粉材料科技有限公司 | 一种复合挤出法生产淀粉基软胶囊的方法 |
| CN103893771B (zh) * | 2014-04-21 | 2015-08-26 | 湖南尔康制药股份有限公司 | 一种用于生产淀粉材料软胶囊的成膜组合物及其制备方法 |
| CA2910865C (en) | 2014-07-15 | 2016-11-29 | Isa Odidi | Compositions and methods for reducing overdose |
| US10220047B2 (en) | 2014-08-07 | 2019-03-05 | Opko Ireland Global Holdings, Ltd. | Adjunctive therapy with 25-hydroxyvitamin D and articles therefor |
| CN104337793A (zh) * | 2014-10-16 | 2015-02-11 | 浙江春宝胶囊有限公司 | 一种非明胶软胶囊壳的配方 |
| US9918947B2 (en) | 2015-11-23 | 2018-03-20 | Undoo, LLC | Composition of olivetol and method of use to reduce or inhibit the effects of tetrahydrocannabinol in the human body |
| JP6926453B2 (ja) * | 2015-12-03 | 2021-08-25 | 大正製薬株式会社 | カプセル組成物 |
| MY198547A (en) | 2016-03-28 | 2023-09-04 | Opko Ireland Global Holdings Ltd | Methods of vitamin d treatment |
| WO2017205673A1 (en) * | 2016-05-25 | 2017-11-30 | TSI Group Ltd. | Stabilization of beta-hydroxyisovaleric acid formulations in soft gel capsules |
| CN117126069A (zh) | 2017-03-03 | 2023-11-28 | 因思博纳公司 | 具有改善的稳定性的制剂 |
| US10711119B2 (en) | 2018-01-10 | 2020-07-14 | Cp Kelco Aps | Carrageenan-based compositions for films and capsules |
| CA3148082A1 (en) * | 2019-07-23 | 2021-01-28 | R.P. Scherer Technologies, Llc | Softshell capsule formulations, and methods of preparation and use thereof |
| IL307253A (en) * | 2021-04-01 | 2023-11-01 | Scherer Technologies Llc R P | Phospholipids as anion chelating agents in pharmaceutical formulations |
| CA3224069A1 (en) * | 2021-07-06 | 2023-01-12 | Karunakar Sukuru | Softgel capsule |
| AU2021107198A4 (en) * | 2021-08-24 | 2021-12-09 | Blackmores Ltd | A softgel capsule composition, and a process for producing a softgel capsule therefrom |
| EP4176724A1 (en) | 2021-11-09 | 2023-05-10 | Universität Hohenheim | Use of an oleogel as a layer or coating |
| JP2025527331A (ja) * | 2022-08-12 | 2025-08-20 | アール．ピー．シェーラー テクノロジーズ，エルエルシー | 速溶性ソフトゲルカプセル |
| WO2025042689A1 (en) * | 2023-08-18 | 2025-02-27 | R.P. Scherer Technologies, Llc | Softgel capsule including a non-steroidal anti-inflammatory drug and acetaminophen |
| WO2025064293A1 (en) * | 2023-09-18 | 2025-03-27 | R.P. Scherer Technologies, Llc | Fast dissolving softgel capsules including ibuprofen |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2118040A (en) | 1982-02-15 | 1983-10-26 | Hoechst Uk Ltd | Oral anti-diabetic preparation |
| DE3307353C2 (de) | 1983-03-02 | 1985-01-31 | R.P. Scherer GmbH, 6930 Eberbach | Polyethylenglykolhaltige Weichgelatinekapsel und Verfahren zu ihrer Herstellung |
| GB8305693D0 (en) | 1983-03-02 | 1983-04-07 | Scherer Ltd R P | Pharmaceutical compositions |
| US5071643A (en) | 1986-10-17 | 1991-12-10 | R. P. Scherer Corporation | Solvent system enhancing the solubility of pharmaceuticals for encapsulation |
| JPS63164858A (ja) * | 1986-12-27 | 1988-07-08 | Unie Koroido Kk | 軟カプセルの外皮 |
| JPH0525037A (ja) | 1991-07-01 | 1993-02-02 | Upjohn Co:The | 経口投与酵素感受性腸溶製剤 |
| GB9226238D0 (en) | 1992-12-16 | 1993-02-10 | Scherer Ltd R P | Encapsulation apparatus and process |
| US5376688A (en) | 1992-12-18 | 1994-12-27 | R. P. Scherer Corporation | Enhanced solubility pharmaceutical solutions |
| US5505961A (en) | 1993-08-05 | 1996-04-09 | R. P. Scherer Corporation | Gelatin capsules containing a highly concentrated acetaminophen solution |
| GB9705770D0 (en) | 1997-03-20 | 1997-05-07 | Scherer Corp R P | Gelatin encapsulation techniques |
| US20030104048A1 (en) | 1999-02-26 | 2003-06-05 | Lipocine, Inc. | Pharmaceutical dosage forms for highly hydrophilic materials |
| US6340473B1 (en) | 1999-07-07 | 2002-01-22 | R.P. Scherer Technologies, Inc. | Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same |
| US6387400B1 (en) | 2000-08-29 | 2002-05-14 | R.P. Scherer Technologies, Inc. | Process for preparing pharmaceutical compositions for use with soft gelatin formulations |
| US6884060B2 (en) | 2001-11-02 | 2005-04-26 | R.P. Scherer Technologies, Inc. | Apparatus for manufacturing encapsulated products |
| US7887838B2 (en) | 2002-01-18 | 2011-02-15 | Banner Pharmacaps, Inc. | Non-gelatin film and method and apparatus for producing same |
| WO2004024126A1 (en) * | 2002-09-13 | 2004-03-25 | Cydex, Inc. | Capsules containing aqueous fill compositions stabilized with derivatized cyclodextrin |
| JP2004250369A (ja) * | 2003-02-19 | 2004-09-09 | Fuji Capsule Kk | 軟カプセル剤皮膜組成物 |
| US20050137262A1 (en) | 2003-12-22 | 2005-06-23 | Hu Patrick C. | Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses |
-
2004
- 2004-11-08 US US10/984,205 patent/US8231896B2/en active Active
-
2005
- 2005-10-26 SI SI200531747T patent/SI1809261T1/sl unknown
- 2005-10-26 PL PL05823349T patent/PL1809261T3/pl unknown
- 2005-10-26 JP JP2007540346A patent/JP5192816B2/ja not_active Expired - Lifetime
- 2005-10-26 AT AT05823349T patent/ATE536866T1/de active
- 2005-10-26 DK DK05823349.5T patent/DK1809261T3/da active
- 2005-10-26 ES ES10194764.6T patent/ES2603225T3/es not_active Expired - Lifetime
- 2005-10-26 BR BRPI0517674A patent/BRPI0517674B8/pt active IP Right Grant
- 2005-10-26 PT PT05823349T patent/PT1809261E/pt unknown
- 2005-10-26 WO PCT/US2005/038532 patent/WO2006052452A1/en not_active Ceased
- 2005-10-26 EP EP10194764.6A patent/EP2289496B1/en not_active Expired - Lifetime
- 2005-10-26 AU AU2005305232A patent/AU2005305232B2/en not_active Expired
- 2005-10-26 EP EP05823349A patent/EP1809261B1/en not_active Expired - Lifetime
- 2005-10-26 CA CA2585721A patent/CA2585721C/en not_active Expired - Lifetime
- 2005-10-26 ES ES05823349T patent/ES2379970T3/es not_active Expired - Lifetime
- 2005-10-26 MX MX2007005403A patent/MX2007005403A/es active IP Right Grant
- 2005-11-08 PE PE2005001306A patent/PE20061136A1/es not_active Application Discontinuation
- 2005-11-08 TW TW094139199A patent/TWI405592B/zh not_active IP Right Cessation
- 2005-11-08 UY UY29200A patent/UY29200A1/es not_active IP Right Cessation
- 2005-11-08 AR ARP050104668A patent/AR051237A1/es not_active Application Discontinuation
-
2012
- 2012-03-14 CY CY20121100264T patent/CY1112518T1/el unknown
- 2012-07-06 US US13/543,244 patent/US8377470B2/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
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| HC | Change of company name or juridical status | ||
| FG | Grant or registration |