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MD3995B1 - Utilizare a di(µ-Ofenoxi)-di{[2-(4-aminobenzensulfamido)-5-etil-1,3,4-tiadiazol]-3,5-dibromosalicilidentiosemicarbazonato(-1)-cupru} in calitate de inhibitor al proliferarii celulelor T-47D ale cancerului mamar - Google Patents

Utilizare a di(µ-Ofenoxi)-di{[2-(4-aminobenzensulfamido)-5-etil-1,3,4-tiadiazol]-3,5-dibromosalicilidentiosemicarbazonato(-1)-cupru} in calitate de inhibitor al proliferarii celulelor T-47D ale cancerului mamar

Info

Publication number
MD3995B1
MD3995B1 MDA20090050A MD20090050A MD3995B1 MD 3995 B1 MD3995 B1 MD 3995B1 MD A20090050 A MDA20090050 A MD A20090050A MD 20090050 A MD20090050 A MD 20090050A MD 3995 B1 MD3995 B1 MD 3995B1
Authority
MD
Moldova
Prior art keywords
inhibitor
cell proliferation
mammary cancer
dibromosalicylidenethiosemicarbazonato
aminobenzenesulfamido
Prior art date
Application number
MDA20090050A
Other languages
English (en)
Other versions
MD3995C2 (ro
Inventor
Aurelian Gulea
Victor Tapcov
Donald Poirier
Valeriu Rudic
Original Assignee
Universitatea De Stat Din Moldova
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitatea De Stat Din Moldova filed Critical Universitatea De Stat Din Moldova
Priority to MDA20090050A priority Critical patent/MD3995C2/ro
Publication of MD3995B1 publication Critical patent/MD3995B1/ro
Publication of MD3995C2 publication Critical patent/MD3995C2/ro

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Inventia se refera la chimie, si anume la utilizarea compusului coordinativ din clasa tiosemicarbazonatilor metalelor de tranzitie in calitate de inhibitor al proliferarii celulelor T-47D ale cancerului mamar. Esenta inventiei consta in utilizarea in calitate de inhibitor al proliferarii celulelor T-47D ale cancerului mamar a di(µ-Ofenoxi)-di{[2-(4-aminobenzensulfamido)-5-etil-1,3,4-tiadiazol]-3,5-dibromosalicilidentiosemicarbazonato(-1)-cupru} cu formula :
MDA20090050A 2009-05-11 2009-05-11 Utilizare a di(µ-Ofenoxi)-di{[2-(4-aminobenzensulfamido)-5-etil-1,3,4-tiadiazol]-3,5-dibromosalicilidentiosemicarbazonato(-1)-cupru} în calitate de inhibitor al proliferării celulelor T-47D ale cancerului mamar MD3995C2 (ro)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20090050A MD3995C2 (ro) 2009-05-11 2009-05-11 Utilizare a di(µ-Ofenoxi)-di{[2-(4-aminobenzensulfamido)-5-etil-1,3,4-tiadiazol]-3,5-dibromosalicilidentiosemicarbazonato(-1)-cupru} în calitate de inhibitor al proliferării celulelor T-47D ale cancerului mamar

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20090050A MD3995C2 (ro) 2009-05-11 2009-05-11 Utilizare a di(µ-Ofenoxi)-di{[2-(4-aminobenzensulfamido)-5-etil-1,3,4-tiadiazol]-3,5-dibromosalicilidentiosemicarbazonato(-1)-cupru} în calitate de inhibitor al proliferării celulelor T-47D ale cancerului mamar

Publications (2)

Publication Number Publication Date
MD3995B1 true MD3995B1 (ro) 2009-12-31
MD3995C2 MD3995C2 (ro) 2010-07-31

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20090050A MD3995C2 (ro) 2009-05-11 2009-05-11 Utilizare a di(µ-Ofenoxi)-di{[2-(4-aminobenzensulfamido)-5-etil-1,3,4-tiadiazol]-3,5-dibromosalicilidentiosemicarbazonato(-1)-cupru} în calitate de inhibitor al proliferării celulelor T-47D ale cancerului mamar

Country Status (1)

Country Link
MD (1) MD3995C2 (ro)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4132C1 (ro) * 2010-12-13 2012-05-31 Государственный Университет Молд0 Di(µ-S)-bis{cloro-[fenil(piridin-2-il)metanon-tiosemicarbazonato(1-)]cupru} care manifestă proprietatea de inhibare a proliferării celulelor T-47D ale cancerului mamar
MD4349C1 (ro) * 2014-06-23 2015-12-31 Государственный Университет Молд0 Compusul N-(3-metoxifenil)-2-(piridin-2-ilmetilen)-hidrazincarbotioamidă - inhibitor al proliferării celulelor MeW-164 ale melanomului uman
MD4520B1 (ro) * 2016-12-16 2017-10-31 Государственный Университет Молд0 N-(4-butoxifenil)-2-(piridin-2-ilmetiliden)hidrazincarbotioamida în calitate de inhibitor al proliferării celulelor T-47D ale cancerului mamar

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SU639252A1 (ru) * 1975-07-09 1999-12-27 РќРѕСЃРєРѕРІ Р¤.РЎ. Фосфорилированные тиосемикарбазоны, обладающие антивирусной активностью
IL87405A0 (en) * 1987-08-12 1989-01-31 Immunomedics Inc Radiolabeled agents and methods and kits for the production thereof
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MD195C2 (ro) * 1994-12-05 1995-11-30 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Complecsuri ale cuprului cu proprietăţi antistafilococice
US5767134A (en) * 1997-05-15 1998-06-16 Vion Pharmaceuticals, Inc. Prodrug forms of ribonucleotide reductase inhibitors 3-AP and 3-AMP
US5869676A (en) * 1997-05-15 1999-02-09 Vion Pharmaceuticals, Inc. Process for the synthesis of ribonucleotide reductase inhibitors 3-AP and 3-AMP
EP1193261A1 (en) * 2000-10-02 2002-04-03 Warner-Lambert Company New thiadiazoles and their use as phosphodiesterase-7 inhibitors
KR100456047B1 (ko) * 2000-12-22 2004-11-08 이인원 애피시딘 유도체, 이의 합성방법 및 이를 포함하는 항암제조성물
MD1812C2 (ro) * 2000-12-29 2002-06-30 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Complecşi de cupru ca inhibitori de bacterii şi fungi
MD2003C2 (ro) * 2001-01-10 2003-03-31 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Complecşi interni de cupru (II) cu acţiune antimicrobiană şi antimicotică
MD2942C2 (ro) * 2004-04-27 2006-06-30 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Di(µ-O)-bis(3,5-dibromsalicilidentiosemicarbazonatocupru)
MD3124C2 (ro) * 2005-05-25 2007-03-31 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Salicilidentiosemicarbazidaţi de cupru(II) care conţin sulfanilamide
CN1891701A (zh) * 2005-07-07 2007-01-10 桑迪亚医药技术（上海）有限责任公司 杂芳环缩氨基硫脲类化合物及其衍生物和它们在制备抗肿瘤药物中的应用
GB0607899D0 (en) * 2006-04-03 2006-05-31 Glaxo Group Ltd Process for preparing heterocyclic derivatives
MD3655G2 (ro) * 2007-09-03 2009-02-28 Государственный Университет Молд0 Inhibitor al leucemiei mieloide umane în bază de bis(2-hidroxi-8-fenil-triciclo/7.3.1.0.2,7/tridecan-13-on-tiosemicarbazonato)cupru
MD3890G2 (ro) * 2008-09-08 2009-12-31 Государственный Университет Молд0 Inhibitori ai leucemiei mieloide umane în baza compuşilor coordinativi ai cuprului(II) cu salicilidentiosemicarbazide

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4132C1 (ro) * 2010-12-13 2012-05-31 Государственный Университет Молд0 Di(µ-S)-bis{cloro-[fenil(piridin-2-il)metanon-tiosemicarbazonato(1-)]cupru} care manifestă proprietatea de inhibare a proliferării celulelor T-47D ale cancerului mamar
MD4349C1 (ro) * 2014-06-23 2015-12-31 Государственный Университет Молд0 Compusul N-(3-metoxifenil)-2-(piridin-2-ilmetilen)-hidrazincarbotioamidă - inhibitor al proliferării celulelor MeW-164 ale melanomului uman
MD4520B1 (ro) * 2016-12-16 2017-10-31 Государственный Университет Молд0 N-(4-butoxifenil)-2-(piridin-2-ilmetiliden)hidrazincarbotioamida în calitate de inhibitor al proliferării celulelor T-47D ale cancerului mamar

Also Published As

Publication number Publication date
MD3995C2 (ro) 2010-07-31

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Legal Events

Date Code Title Description
FG4A Patent for invention issued
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees