MC1186A1 - Derives de quinazoline - Google Patents

Derives de quinazoline

Info

Publication number: MC1186A1
Authority: MC; Monaco
Prior art keywords: formula; compound; compounds; radical; hydrogen
Prior art date: 1977-03-24

Application number

MC781292A

Other languages

English (en)

French (fr)

Inventor

Kierstead R Wightman

Tilley J Wright

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-03-24

Filing date

1978-03-22

Publication date

1978-12-22

1978-03-22 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1978-12-22 Publication of MC1186A1 publication Critical patent/MC1186A1/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C205/59—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pulmonology (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Plural Heterocyclic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

MC781292A 1977-03-24 1978-03-22 Derives de quinazoline MC1186A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US78093977A	1977-03-24	1977-03-24
US87156478A	1978-01-23	1978-01-23

Publications (1)

Publication Number	Publication Date
MC1186A1 true MC1186A1 (fr)	1978-12-22

Family

ID=27119777

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
MC781292A MC1186A1 (fr)	1977-03-24	1978-03-22	Derives de quinazoline
MC781291A MC1185A1 (fr)	1977-03-24	1978-03-22	Derives de quinazoline

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
MC781291A MC1185A1 (fr)	1977-03-24	1978-03-22	Derives de quinazoline

Country Status (23)

Country	Link
JP (2)	JPS53119896A (el)
AR (3)	AR218480A1 (el)
AT (2)	AT367051B (el)
AU (2)	AU521352B2 (el)
DE (2)	DE2812585A1 (el)
DK (2)	DK128878A (el)
ES (13)	ES468126A1 (el)
FI (2)	FI780918A7 (el)
FR (2)	FR2384771A1 (el)
GB (2)	GB1601991A (el)
GR (2)	GR72948B (el)
HU (1)	HU180782B (el)
IE (1)	IE46505B1 (el)
IL (2)	IL54328A (el)
IT (2)	IT1093710B (el)
LU (2)	LU79290A1 (el)
MC (2)	MC1186A1 (el)
NL (2)	NL7803112A (el)
NO (2)	NO781053L (el)
NZ (2)	NZ186760A (el)
PH (2)	PH13915A (el)
PT (2)	PT67820A (el)
SE (2)	SE7803418L (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2557425C2 (de)	1975-12-19	1987-03-19	C.H. Boehringer Sohn, 6507 Ingelheim	11-Oxo-11-H-pyrido[2,1-b]-chinazolin-2-carbonsäure und ihre Salze, Verfahren zu ihrer Herstellung und Arzneimittel
DE2845766A1 (de) *	1978-10-18	1980-04-30	Schering Ag	Pyrido eckige klammer auf 2,1-b eckige klammer zu -chinazolinon-derivate, ihre herstellung und verwendung
US4395549A (en)	1981-10-02	1983-07-26	Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.	6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
ES511866A0 (es) *	1982-04-30	1983-06-01	Lafarquim	"procedimiento de obtencion de 2-isopropil pirido (2-1-b) quinazolinas y sus sales no toxicas con actividad antianafilactica".
US4551460A (en) *	1982-05-10	1985-11-05	Hoffmann-La Roche Inc.	Pyrido[2,1-b]quinazoline derivatives useful as agents for treatment of allergic conditions and vascular disorders involving thrombosis
DE3300477A1 (de) *	1983-01-08	1984-07-12	Boehringer Ingelheim KG, 6507 Ingelheim	Neue heterocyclische verbindungen, ihre herstellung und verwendung
JPS62238264A (ja) *	1986-04-04	1987-10-19	Nippon Tokushu Noyaku Seizo Kk	２−ハロ−５−アセチルピリジン

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4012387A (en) *	1975-09-18	1977-03-15	Warner-Lambert Company	Benzo-[g]pyrido[2,1-b]quinazolinones
US4033961A (en) *	1975-10-07	1977-07-05	Warner-Lambert Company	Pyrido[2-1-b]quinazolin-ones and their methods of preparation

1978
- 1978-03-22 PH PH20917A patent/PH13915A/en unknown
- 1978-03-22 NO NO781053A patent/NO781053L/no unknown
- 1978-03-22 DE DE19782812585 patent/DE2812585A1/de not_active Withdrawn
- 1978-03-22 FR FR7808317A patent/FR2384771A1/fr active Granted
- 1978-03-22 FR FR7808316A patent/FR2384770A1/fr active Granted
- 1978-03-22 NL NL7803112A patent/NL7803112A/xx not_active Application Discontinuation
- 1978-03-22 MC MC781292A patent/MC1186A1/fr unknown
- 1978-03-22 HU HU78HO2058A patent/HU180782B/hu unknown
- 1978-03-22 PH PH20918A patent/PH14130A/en unknown
- 1978-03-22 NL NL7803122A patent/NL7803122A/xx not_active Application Discontinuation
- 1978-03-22 LU LU79290A patent/LU79290A1/de unknown
- 1978-03-22 DE DE19782812586 patent/DE2812586A1/de not_active Withdrawn
- 1978-03-22 IL IL54328A patent/IL54328A/xx unknown
- 1978-03-22 MC MC781291A patent/MC1185A1/fr unknown
- 1978-03-22 NZ NZ186760A patent/NZ186760A/xx unknown
- 1978-03-22 ES ES468126A patent/ES468126A1/es not_active Expired
- 1978-03-22 DK DK128878A patent/DK128878A/da not_active Application Discontinuation
- 1978-03-22 LU LU79293A patent/LU79293A1/de unknown
- 1978-03-22 ES ES468127A patent/ES468127A1/es not_active Expired
- 1978-03-22 NZ NZ186759A patent/NZ186759A/xx unknown
- 1978-03-22 DK DK132778A patent/DK132778A/da not_active IP Right Cessation
- 1978-03-22 NO NO781051A patent/NO781051L/no unknown
- 1978-03-22 IL IL54326A patent/IL54326A/xx unknown
- 1978-03-23 FI FI780918A patent/FI780918A7/fi not_active Application Discontinuation
- 1978-03-23 SE SE7803418A patent/SE7803418L/xx unknown
- 1978-03-23 AU AU34474/78A patent/AU521352B2/en not_active Expired
- 1978-03-23 GB GB11705/78A patent/GB1601991A/en not_active Expired
- 1978-03-23 PT PT67820A patent/PT67820A/pt unknown
- 1978-03-23 AT AT0210478A patent/AT367051B/de not_active IP Right Cessation
- 1978-03-23 IT IT7821578A patent/IT1093710B/it active
- 1978-03-23 PT PT67821A patent/PT67821B/pt unknown
- 1978-03-23 FI FI780917A patent/FI780917A7/fi not_active Application Discontinuation
- 1978-03-23 IE IE582/78A patent/IE46505B1/en unknown
- 1978-03-23 SE SE7803419A patent/SE7803419L/xx unknown
- 1978-03-23 GR GR55781A patent/GR72948B/el unknown
- 1978-03-23 GR GR55782A patent/GR73170B/el unknown
- 1978-03-23 AU AU34475/78A patent/AU521096B2/en not_active Expired
- 1978-03-23 GB GB11704/78A patent/GB1601371A/en not_active Expired
- 1978-03-23 AT AT0210278A patent/AT367050B/de not_active IP Right Cessation
- 1978-03-24 JP JP3320578A patent/JPS53119896A/ja active Pending
- 1978-03-24 JP JP3400278A patent/JPS53119897A/ja active Pending
- 1978-03-24 IT IT21655/78A patent/IT1095493B/it active
- 1978-03-27 AR AR271537A patent/AR218480A1/es active
- 1978-03-27 AR AR271538A patent/AR218060A1/es active
1979
- 1979-02-16 ES ES478328A patent/ES478328A1/es not_active Expired
- 1979-02-16 ES ES478333A patent/ES478333A1/es not_active Expired
- 1979-02-16 ES ES478323A patent/ES478323A1/es not_active Expired
- 1979-02-16 ES ES478326A patent/ES478326A1/es not_active Expired
- 1979-02-16 ES ES478327A patent/ES478327A1/es not_active Expired
- 1979-02-16 ES ES478331A patent/ES478331A1/es not_active Expired
- 1979-02-16 ES ES478332A patent/ES478332A1/es not_active Expired
- 1979-02-16 ES ES478330A patent/ES478330A1/es not_active Expired
- 1979-02-16 ES ES478324A patent/ES478324A1/es not_active Expired
- 1979-02-16 ES ES478329A patent/ES478329A1/es not_active Expired
- 1979-02-16 ES ES478325A patent/ES478325A1/es not_active Expired
- 1979-05-10 AR AR276467A patent/AR225415A1/es active

Also Published As

Publication number	Publication date
LU79290A1 (de)	1979-05-25
ES468127A1 (es)	1979-09-16
IL54328A (en)	1982-03-31
AU521096B2 (en)	1982-03-18
ES478330A1 (es)	1979-11-01
IE780582L (en)	1978-09-24
NZ186759A (en)	1981-03-16
DK128878A (da)	1978-09-25
ES478326A1 (es)	1979-11-01
IL54328A0 (en)	1978-06-15
NO781053L (no)	1978-09-26
PH14130A (en)	1981-02-26
ES478328A1 (es)	1979-11-01
ES478325A1 (es)	1979-11-01
DE2812585A1 (de)	1978-09-28
GR72948B (el)	1984-01-17
FI780917A7 (fi)	1978-09-25
ES478329A1 (es)	1979-11-01
NZ186760A (en)	1981-03-16
FR2384771A1 (fr)	1978-10-20
JPS53119897A (en)	1978-10-19
PT67820A (en)	1978-04-01
FR2384770A1 (fr)	1978-10-20
NL7803112A (nl)	1978-09-26
ATA210278A (de)	1981-10-15
PH13915A (en)	1980-11-04
AU3447478A (en)	1979-09-27
NL7803122A (nl)	1978-09-26
SE7803418L (sv)	1978-09-25
IL54326A (en)	1982-04-30
GB1601371A (en)	1981-10-28
IT1095493B (it)	1985-08-10
GB1601991A (en)	1981-11-04
IT1093710B (it)	1985-07-26
PT67821B (en)	1980-03-04
AT367051B (de)	1982-05-25
AR225415A1 (es)	1982-03-31
AT367050B (de)	1982-05-25
ES478323A1 (es)	1979-11-01
ES478333A1 (es)	1979-11-16
ES478324A1 (es)	1979-11-01
GR73170B (el)	1983-02-14
SE7803419L (sv)	1978-09-25
FI780918A7 (fi)	1978-09-25
PT67821A (en)	1978-04-01
IL54326A0 (en)	1978-06-15
MC1185A1 (fr)	1978-12-22
AR218060A1 (es)	1980-05-15
ES478332A1 (es)	1979-11-16
IT7821655A0 (it)	1978-03-24
AR218480A1 (es)	1980-06-13
DE2812586A1 (de)	1978-09-28
LU79293A1 (de)	1979-05-25
ES478331A1 (es)	1979-11-16
IT7821578A0 (it)	1978-03-23
HU180782B (en)	1983-04-29
IE46505B1 (en)	1983-06-29
DK132778A (da)	1978-09-25
JPS53119896A (en)	1978-10-19
AU521352B2 (en)	1982-04-01
NO781051L (no)	1978-09-26
AU3447578A (en)	1979-09-27
ES468126A1 (es)	1979-09-01
FR2384770B1 (el)	1980-10-24
ES478327A1 (es)	1979-11-01
FR2384771B1 (el)	1980-04-04
ATA210478A (de)	1981-10-15

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CA2104883A1 (fr)	1994-02-28	Derives d'acide thienyl ou pyrrolyl carboxyliques, leur preparation et medicaments les contenant
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CH655114A5 (fr)	1986-03-27	Derives de l'imidazotetrazinone, leur preparation et compositions pharmaceutiques les contenant.
MC1333A1 (fr)	1981-04-21	Derives de quinazoline
CH643257A5 (fr)	1984-05-30	Derives tricycliques et leurs sels, leurs procedes de preparation et medicaments les renfermant.
CH630085A5 (fr)	1982-05-28	Nouvelles imidazoquinoleines et leurs sels, procede de preparation et compositions pharmaceutiques.
MC1186A1 (fr)	1978-12-22	Derives de quinazoline
MC1255A1 (fr)	1980-01-14	L'acide 7-methoxy-5-oxo-5h-thiazolo(2,3-b)quinazoline-2-carboxylique et ses sels,leur preparation et leurs utilisations therapeutiques
EP0463944B1 (fr)	1994-10-05	Acyl benzoxazolinones, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
CH644124A5 (fr)	1984-07-13	Oxoimidazoquinoxalines et leurs sels, leurs procedes de preparation et les medicaments les renfermant.
FR2551063A1 (fr)	1985-03-01	Nouveaux dimethyl-2,5 pyrroles, leur procede de preparation et leur application en therapeutique
FR2530633A1 (fr)	1984-01-27	Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur preparation, leur application comme medicament, et les compositions les renfermant
EP0062580B1 (fr)	1985-11-06	Dérivés de l'imidazo(1,2-a)quinoléines
MC1356A1 (fr)	1981-08-10	Derives de quinazoline
CH650254A5 (fr)	1985-07-15	Quinolones, leurs procedes de preparation et compositions therapeutiques les contenant.
MC1347A1 (fr)	1981-06-22	Derives de pyridazopyridazine
EP0223647B1 (fr)	1990-08-01	Alkylcarboxamides de pyridylalkylamines, leurs préparations et leur utilisation en tant que médicaments
EP0017578A1 (fr)	1980-10-15	Acides 5-(2-hydroxy-3-thiopropoxy)chromone-2-carboxyliques, leurs sels et esters, procédé de préparation et médicaments
EP0233800A1 (fr)	1987-08-26	Dérivés d'imidazo[1,2-a]quinoléines, leur préparation et leur application en thérapeutique
EP0663903B1 (fr)	1997-04-23	Derives de dihydro-1,2 oxo-2 amino-3 quinoxalines, leur preparation et leur application en therapeutique
MC1135A1 (fr)	1977-11-18	Derives de thiazine
JPS6183179A (ja)	1986-04-26	新規フラボン誘導体

Legal Events

Date	Code	Title	Description
1982-02-19	YP	Annual fee paid