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MA53927B1 - Composition pharmaceutique pour une administration par voie orale comprenant un dérivé d'aminopyrimidine ou son sel - Google Patents

Composition pharmaceutique pour une administration par voie orale comprenant un dérivé d'aminopyrimidine ou son sel

Info

Publication number
MA53927B1
MA53927B1 MA53927A MA53927A MA53927B1 MA 53927 B1 MA53927 B1 MA 53927B1 MA 53927 A MA53927 A MA 53927A MA 53927 A MA53927 A MA 53927A MA 53927 B1 MA53927 B1 MA 53927B1
Authority
MA
Morocco
Prior art keywords
pharmaceutical composition
oral administration
salt
aminopyrimidine derivative
aminopyrimidine
Prior art date
Application number
MA53927A
Other languages
English (en)
Other versions
MA53927A (fr
Inventor
Seongkyu Kim
Deokkyu Lee
Soo-Won Kim
Jun-Mo Yang
Yoong-Sik Park
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Publication of MA53927A publication Critical patent/MA53927A/fr
Publication of MA53927B1 publication Critical patent/MA53927B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
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    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Hospice & Palliative Care (AREA)
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  • Psychology (AREA)

Abstract

La présente invention concerne une composition pharmaceutique pour une administration par voie orale comprenant : du n-(5-(4-(4-((diméthylamino)méthyl)-3-phényl-1h-pyrazol-1-yl)pirimidin-2-ylamino)-4-méthoxy-2-morpholinophényl)acrylamide (lazertinib) ou son sel pharmaceutiquement acceptable en tant que principe actif ; et une combinaison de cellulose microcristalline et de mannitol en tant que diluant.
MA53927A 2018-10-18 2019-10-17 Composition pharmaceutique pour une administration par voie orale comprenant un dérivé d'aminopyrimidine ou son sel MA53927B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020180124171A KR20200043618A (ko) 2018-10-18 2018-10-18 아미노피리미딘 유도체 또는 이의 염을 포함하는 경구투여용 약학 조성물
PCT/IB2019/058862 WO2020079637A1 (fr) 2018-10-18 2019-10-17 Composition pharmaceutique pour une administration par voie orale comprenant un dérivé d'aminopyrimidine ou son sel

Publications (2)

Publication Number Publication Date
MA53927A MA53927A (fr) 2021-09-15
MA53927B1 true MA53927B1 (fr) 2023-12-29

Family

ID=70282933

Family Applications (1)

Application Number Title Priority Date Filing Date
MA53927A MA53927B1 (fr) 2018-10-18 2019-10-17 Composition pharmaceutique pour une administration par voie orale comprenant un dérivé d'aminopyrimidine ou son sel

Country Status (31)

Country Link
US (1) US12318390B2 (fr)
EP (2) EP4306113A3 (fr)
JP (2) JP7369769B2 (fr)
KR (3) KR20200043618A (fr)
CN (2) CN113015521B (fr)
AR (1) AR117655A1 (fr)
AU (2) AU2019360446B2 (fr)
BR (1) BR112021007061A2 (fr)
CA (1) CA3116652A1 (fr)
DK (1) DK3866767T3 (fr)
EA (1) EA202191061A1 (fr)
ES (1) ES2968966T3 (fr)
FI (1) FI3866767T3 (fr)
HR (1) HRP20231670T1 (fr)
HU (1) HUE065389T2 (fr)
IL (1) IL282163B2 (fr)
LT (1) LT3866767T (fr)
MA (1) MA53927B1 (fr)
MD (1) MD3866767T2 (fr)
MX (2) MX2021004457A (fr)
MY (1) MY208983A (fr)
PE (1) PE20211818A1 (fr)
PH (1) PH12021550687A1 (fr)
PL (1) PL3866767T3 (fr)
PT (1) PT3866767T (fr)
RS (1) RS65012B1 (fr)
SG (1) SG11202103057RA (fr)
SI (1) SI3866767T1 (fr)
SM (1) SMT202300491T1 (fr)
TW (1) TWI831848B (fr)
WO (1) WO2020079637A1 (fr)

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Publication number Priority date Publication date Assignee Title
AR111469A1 (es) 2017-04-21 2019-07-17 Yuhan Corp Sal de un compuesto del derivado de aminopiridina, una forma cristalina de la misma, y un proceso para preparar la misma
WO2020230091A1 (fr) * 2019-05-14 2020-11-19 Janssen Biotech, Inc. Polythérapies avec des anticorps anti-egfr/c-met bispécifiques et des inhibiteurs de tyrosine kinase egfr de troisième génération
US11850248B2 (en) 2019-05-14 2023-12-26 Yuhan Corporation Therapies with 3rd generation EGFR tyrosine kinase inhibitors
JOP20220184A1 (ar) 2020-02-12 2023-01-30 Janssen Biotech Inc علاج مصابي السرطان ممن لديهم طفرات تخطي c-Met إكسون14
TW202207940A (zh) * 2020-04-14 2022-03-01 美商健生生物科技公司 包含胺基嘧啶衍生物或其醫藥上可接受之鹽、水合物、或溶劑化物之用於經口投予之醫藥組成物
WO2022253261A1 (fr) * 2021-06-01 2022-12-08 杭州领业医药科技有限公司 Forme cristalline d'hydrate de méthanesulfonate de lazertinib, son procédé de préparation et son utilisation
CA3228195A1 (en) 2023-05-23 2025-06-30 Janssen Biotech, Inc. Methods for treatment of non-small cell lung cancer (nsclc)
WO2025052273A1 (fr) 2023-09-05 2025-03-13 Janssen Biotech, Inc. Méthodes pour traiter le cancer du poumon non à petites cellules
WO2025206726A1 (fr) * 2024-03-26 2025-10-02 (주)신테카바이오 Composition pharmaceutique pour la prévention ou le traitement de maladies liées à la dépression ou à l'anxiété, contenant du lazertinib ou un sel pharmaceutiquement acceptable de celui-ci

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AR111469A1 (es) * 2017-04-21 2019-07-17 Yuhan Corp Sal de un compuesto del derivado de aminopiridina, una forma cristalina de la misma, y un proceso para preparar la misma
TW202207940A (zh) * 2020-04-14 2022-03-01 美商健生生物科技公司 包含胺基嘧啶衍生物或其醫藥上可接受之鹽、水合物、或溶劑化物之用於經口投予之醫藥組成物

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Publication number Publication date
SG11202103057RA (en) 2021-05-28
MD3866767T2 (ro) 2024-06-30
PL3866767T3 (pl) 2024-04-02
KR20200043618A (ko) 2020-04-28
EP3866767A4 (fr) 2022-07-20
JP2022504943A (ja) 2022-01-13
IL282163B1 (en) 2025-05-01
AU2019360446B2 (en) 2024-09-19
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IL282163B2 (en) 2025-09-01
EP3866767B1 (fr) 2023-11-29
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WO2020079637A1 (fr) 2020-04-23
AU2024216519B2 (en) 2025-11-20
MA53927A (fr) 2021-09-15
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EP4306113A2 (fr) 2024-01-17
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US20210322428A1 (en) 2021-10-21
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MY208983A (en) 2025-06-14
DK3866767T3 (da) 2024-01-29
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CN119523922A (zh) 2025-02-28
BR112021007061A2 (pt) 2021-07-20
JP2024016052A (ja) 2024-02-06
EP4306113A3 (fr) 2024-02-14
AU2024216519A1 (en) 2024-09-19
CA3116652A1 (fr) 2020-04-23
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HUE065389T2 (hu) 2024-05-28
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EP3866767A1 (fr) 2021-08-25

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