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MA47440B1 - Sulfonylurées, composés apparentés, et leur utilisation - Google Patents

Sulfonylurées, composés apparentés, et leur utilisation

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Publication number
MA47440B1
MA47440B1 MA47440A MA47440A MA47440B1 MA 47440 B1 MA47440 B1 MA 47440B1 MA 47440 A MA47440 A MA 47440A MA 47440 A MA47440 A MA 47440A MA 47440 B1 MA47440 B1 MA 47440B1
Authority
MA
Morocco
Prior art keywords
related compounds
sulfonylureas
nlrp3 inflammasome
useful
compounds
Prior art date
Application number
MA47440A
Other languages
English (en)
Other versions
MA47440A (fr
Inventor
Luke O'neill
Matthew Cooper
Avril Robertson
Kate Schroder
Rebecca Coll
Original Assignee
The Provost Fellows Found Scholars And The Other Members Of Board Of The College Of The Holy & Undiv
Univ Queensland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56691944&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA47440(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from AU2015900507A external-priority patent/AU2015900507A0/en
Application filed by The Provost Fellows Found Scholars And The Other Members Of Board Of The College Of The Holy & Undiv, Univ Queensland filed Critical The Provost Fellows Found Scholars And The Other Members Of Board Of The College Of The Holy & Undiv
Publication of MA47440A publication Critical patent/MA47440A/fr
Publication of MA47440B1 publication Critical patent/MA47440B1/fr

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    • C—CHEMISTRY; METALLURGY
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    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
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    • C07—ORGANIC CHEMISTRY
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    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52—Y being a hetero atom
    • C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • C07C311/56—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of rings other than six-membered aromatic rings
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    • C07C311/60—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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Abstract

La présente invention concerne certaines sulfonylurées et composés apparentés qui ont des propriétés avantageuses et présentent une activité utile dans l'inhibition de l'activation de l'inflammasome nlrp3. De tels composés sont utiles dans le traitement d'un large éventail de troubles dans lesquels le processus d'inflammation, ou plus spécifiquement l'inflammasome nlrp3, a été impliqué comme étant un facteur clé.
MA47440A 2015-02-16 2016-02-16 Sulfonylurées, composés apparentés, et leur utilisation MA47440B1 (fr)

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AU2015900507A AU2015900507A0 (en) 2015-02-16 Sulfonylureas and related compounds and use of same

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MA47440A MA47440B1 (fr) 2015-02-16 2016-02-16 Sulfonylurées, composés apparentés, et leur utilisation
MA056473A MA56473A (fr) 2015-02-16 2016-02-16 Sulfonylurées, composés apparentés, et leur utilisation

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