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MA38857B1 - Dérivés de 1-(pipérazin-1-yl)-2-([1,2,4]triazol-1-yl)-éthanone - Google Patents

Dérivés de 1-(pipérazin-1-yl)-2-([1,2,4]triazol-1-yl)-éthanone

Info

Publication number
MA38857B1
MA38857B1 MA38857A MA38857A MA38857B1 MA 38857 B1 MA38857 B1 MA 38857B1 MA 38857 A MA38857 A MA 38857A MA 38857 A MA38857 A MA 38857A MA 38857 B1 MA38857 B1 MA 38857B1
Authority
MA
Morocco
Prior art keywords
ethanone
piperazin
triazol
derivatives
compounds
Prior art date
Application number
MA38857A
Other languages
English (en)
Other versions
MA38857A1 (fr
Inventor
Eva Caroff
Emmanuel Meyer
Original Assignee
Idorsia Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51225512&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA38857(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Idorsia Pharmaceuticals Ltd filed Critical Idorsia Pharmaceuticals Ltd
Publication of MA38857A1 publication Critical patent/MA38857A1/fr
Publication of MA38857B1 publication Critical patent/MA38857B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

La présente invention concerne des composés de formule (i); des sels pharmaceutiquement acceptables de ceux-ci, et l'utilisation de tels composés en tant que médicaments, en particulier en tant que modulateurs du récepteur cxcr3 dans le traitement des etats inflammatoirs.
MA38857A 2013-07-22 2014-07-21 Dérivés de 1-(pipérazin-1-yl)-2-([1,2,4]triazol-1-yl)-éthanone MA38857B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2013056001 2013-07-22
PCT/EP2014/065639 WO2015011099A1 (fr) 2013-07-22 2014-07-21 Dérivés de 1-(pipérazin-1-yl)-2-([1,2,4]triazol-1-yl)-éthanone

Publications (2)

Publication Number Publication Date
MA38857A1 MA38857A1 (fr) 2018-03-30
MA38857B1 true MA38857B1 (fr) 2018-10-31

Family

ID=51225512

Family Applications (1)

Application Number Title Priority Date Filing Date
MA38857A MA38857B1 (fr) 2013-07-22 2014-07-21 Dérivés de 1-(pipérazin-1-yl)-2-([1,2,4]triazol-1-yl)-éthanone

Country Status (22)

Country Link
US (1) US10259807B2 (fr)
EP (1) EP3024832B1 (fr)
JP (1) JP6330040B2 (fr)
KR (1) KR102295416B1 (fr)
CN (1) CN105658649B (fr)
AR (1) AR096984A1 (fr)
AU (1) AU2014295123B2 (fr)
BR (1) BR112016001238B1 (fr)
CA (1) CA2916338C (fr)
CL (1) CL2016000152A1 (fr)
EA (1) EA030067B1 (fr)
ES (1) ES2671323T3 (fr)
IL (1) IL243650A0 (fr)
MA (1) MA38857B1 (fr)
MX (1) MX363432B (fr)
PH (1) PH12016500134B1 (fr)
PL (1) PL3024832T3 (fr)
SA (1) SA516370398B1 (fr)
SG (1) SG11201600504TA (fr)
TR (1) TR201807959T4 (fr)
TW (1) TWI630205B (fr)
WO (1) WO2015011099A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201600504TA (en) 2013-07-22 2016-02-26 Actelion Pharmaceuticals Ltd 1-(piperazin-1-yl)-2-([1,2,4]triazol-1-yl)-ethanone derivatives
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AR103399A1 (es) * 2015-01-15 2017-05-10 Actelion Pharmaceuticals Ltd Derivados de (r)-2-metil-piperazina como moduladores del receptor cxcr3
WO2018011265A1 (fr) 2016-07-13 2018-01-18 Idorsia Pharmaceuticals Ltd Dérivés de l'hydroxyalkyl pipérazine utilisés comme modulateurs du récepteur cxcr3

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Also Published As

Publication number Publication date
MX2016000938A (es) 2016-05-05
AU2014295123A1 (en) 2016-03-10
MX363432B (es) 2019-03-22
CA2916338A1 (fr) 2015-01-29
KR20160033218A (ko) 2016-03-25
CN105658649B (zh) 2019-03-22
JP6330040B2 (ja) 2018-05-23
ES2671323T3 (es) 2018-06-06
SA516370398B1 (ar) 2017-12-14
EP3024832B1 (fr) 2018-03-28
BR112016001238A8 (pt) 2017-12-26
US20160176862A1 (en) 2016-06-23
CL2016000152A1 (es) 2016-09-02
TWI630205B (zh) 2018-07-21
BR112016001238A2 (pt) 2017-12-12
PL3024832T3 (pl) 2018-10-31
CA2916338C (fr) 2021-07-06
TR201807959T4 (tr) 2018-06-21
TW201536778A (zh) 2015-10-01
CN105658649A (zh) 2016-06-08
PH12016500134A1 (en) 2016-04-18
EA030067B1 (ru) 2018-06-29
AU2014295123B2 (en) 2018-08-02
PH12016500134B1 (en) 2016-04-18
KR102295416B1 (ko) 2021-08-30
MA38857A1 (fr) 2018-03-30
AR096984A1 (es) 2016-02-10
JP2016525137A (ja) 2016-08-22
WO2015011099A1 (fr) 2015-01-29
IL243650A0 (en) 2016-02-29
EA201600123A1 (ru) 2016-07-29
EP3024832A1 (fr) 2016-06-01
SG11201600504TA (en) 2016-02-26
BR112016001238B1 (pt) 2022-10-11
US10259807B2 (en) 2019-04-16

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