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MA34907B1 - Molécules d'anticorps se liant à il-17a et il-17f - Google Patents

Molécules d'anticorps se liant à il-17a et il-17f

Info

Publication number
MA34907B1
MA34907B1 MA36181A MA36181A MA34907B1 MA 34907 B1 MA34907 B1 MA 34907B1 MA 36181 A MA36181 A MA 36181A MA 36181 A MA36181 A MA 36181A MA 34907 B1 MA34907 B1 MA 34907B1
Authority
MA
Morocco
Prior art keywords
antibody molecules
molecules binding
molecules
binding
antibody
Prior art date
Application number
MA36181A
Other languages
English (en)
Inventor
Ralph Adams
Terence Seward Baker
Alastair David Griffiths Lawson
Original Assignee
Ucb Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45496193&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA34907(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ucb Pharma Sa filed Critical Ucb Pharma Sa
Publication of MA34907B1 publication Critical patent/MA34907B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)

Abstract

Molécules d'anticorps ayant une spécificité pour des déterminants antigéniques à la fois de IL-17A et IL-17F, les utilisations thérapeutiques de ces molécules d'anticorps et des procédés d'obtention des dites molécules.
MA36181A 2011-01-14 2012-01-11 Molécules d'anticorps se liant à il-17a et il-17f MA34907B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161432814P 2011-01-14 2011-01-14
PCT/GB2012/050050 WO2012095662A1 (fr) 2011-01-14 2012-01-11 Molécules d'anticorps se liant à il-17a et il-17f

Publications (1)

Publication Number Publication Date
MA34907B1 true MA34907B1 (fr) 2014-02-01

Family

ID=45496193

Family Applications (1)

Application Number Title Priority Date Filing Date
MA36181A MA34907B1 (fr) 2011-01-14 2012-01-11 Molécules d'anticorps se liant à il-17a et il-17f

Country Status (39)

Country Link
US (6) US8580265B2 (fr)
EP (2) EP3219728A1 (fr)
JP (2) JP6028737B2 (fr)
KR (1) KR101950306B1 (fr)
CN (1) CN103384682B (fr)
AR (2) AR084845A1 (fr)
AU (1) AU2012206431B2 (fr)
BR (1) BR112013017951B1 (fr)
CA (1) CA2823812C (fr)
CL (1) CL2013002044A1 (fr)
CO (1) CO6781516A2 (fr)
CY (2) CY1119055T1 (fr)
DK (1) DK2663577T3 (fr)
EA (1) EA037071B1 (fr)
ES (1) ES2632583T3 (fr)
FI (1) FIC20220002I1 (fr)
FR (1) FR22C1000I2 (fr)
HR (1) HRP20171034T1 (fr)
HU (1) HUS2200001I1 (fr)
IL (1) IL227347B (fr)
LT (2) LT2663577T (fr)
LU (1) LUC00246I2 (fr)
MA (1) MA34907B1 (fr)
ME (1) ME02734B (fr)
MX (1) MX341489B (fr)
MY (1) MY162790A (fr)
NL (1) NL301159I2 (fr)
NO (1) NO2021053I1 (fr)
PH (1) PH12013501435B1 (fr)
PL (1) PL2663577T3 (fr)
PT (1) PT2663577T (fr)
RS (1) RS56298B1 (fr)
SG (2) SG191906A1 (fr)
SI (1) SI2663577T1 (fr)
TN (1) TN2013000292A1 (fr)
TW (1) TWI511978B (fr)
UA (1) UA110358C2 (fr)
WO (1) WO2012095662A1 (fr)
ZA (1) ZA201306080B (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0620729D0 (en) * 2006-10-18 2006-11-29 Ucb Sa Biological products
GB0807413D0 (en) * 2008-04-23 2008-05-28 Ucb Pharma Sa Biological products
EP3546483A1 (fr) 2010-05-20 2019-10-02 Ablynx N.V. Matériaux biologiques associés à her3
CN103384682B (zh) 2011-01-14 2017-04-12 Ucb医药有限公司 结合il‑17a和il‑17f的抗体分子
UA117218C2 (uk) 2011-05-05 2018-07-10 Мерк Патент Гмбх Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
MX2019001355A (es) 2012-05-10 2023-01-17 Bioatla Llc Anticuerpos monoclonales multiespecíficos.
GB201310544D0 (en) 2013-06-13 2013-07-31 Ucb Pharma Sa Obtaining an improved therapeutic ligand
HUE052184T2 (hu) * 2013-11-18 2021-12-28 Shanghai hengrui pharmaceutical co ltd IL-17A kötõanyag és felhasználásai
CR20160379A (es) 2014-02-21 2016-10-07 Genentech Inc Anticuerpos biespecificos anti-il 13/il-17 y sus usos
AU2015258859B2 (en) * 2014-05-15 2020-07-23 Rani Therapeutics, Llc Pharmaceutical compositions and methods for fabrication of solid masses comprising polypeptides and/or proteins
TWI713453B (zh) 2014-06-23 2020-12-21 美商健生生物科技公司 干擾素α及ω抗體拮抗劑
AR103173A1 (es) 2014-12-22 2017-04-19 Novarits Ag Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17
CN107407677B (zh) 2015-01-28 2020-07-17 豪夫迈·罗氏有限公司 多发性硬化的基因表达标志和治疗
SG11201802887PA (en) * 2015-10-27 2018-05-30 Ucb Biopharma Sprl Methods of treatment using anti-il-17a/f antibodies
RU2680011C2 (ru) * 2016-04-29 2019-02-14 Закрытое Акционерное Общество "Биокад" Триспецифические антитела против il-17a, il-17f и другой провоспалительной молекулы
KR102329490B1 (ko) 2016-09-14 2021-11-23 베이징 한미 파마슈티컬 컴퍼니 리미티드 Ｉｌ-１７ａ에 특이적으로 결합하는 항체 및 그의 기능성 단편
EP3824906A1 (fr) 2016-12-21 2021-05-26 Amgen Inc. Formulations d'anticorps anti-tnf alpha
US10858427B2 (en) * 2017-03-10 2020-12-08 Suzhou Kanova Biopharmaceutical Co., Ltd. Monoclonal antibody against both IL-17A and IL-17F and use of the same
GB201719447D0 (en) * 2017-11-23 2018-01-10 Ucb Biopharma Sprl Pharmaceutical composition
SG11202012405WA (en) 2018-06-14 2021-01-28 Bioatla Inc Multi-specific antibody constructs
WO2020024931A1 (fr) * 2018-07-31 2020-02-06 Shen Weiqun Anticorps anti-il-17 a et leur utilisation
CN110151999A (zh) * 2019-05-22 2019-08-23 中国人民解放军第四军医大学 用于抑制恶性黑色素瘤进展的靶向药物
MX2022000456A (es) * 2019-07-11 2022-04-18 Wuhan Yzy Biopharma Co Ltd Anticuerpos biespecificos simetricos tetravalentes.
GB201919061D0 (en) * 2019-12-20 2020-02-05 Ucb Biopharma Sprl Multi-specific antibody
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