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MA30654B1 - Therapie tumorale avec anticorps anti-vegf - Google Patents

Therapie tumorale avec anticorps anti-vegf

Info

Publication number
MA30654B1
MA30654B1 MA31650A MA31650A MA30654B1 MA 30654 B1 MA30654 B1 MA 30654B1 MA 31650 A MA31650 A MA 31650A MA 31650 A MA31650 A MA 31650A MA 30654 B1 MA30654 B1 MA 30654B1
Authority
MA
Morocco
Prior art keywords
tumor therapy
vegf antibodies
relates
her2
vegf
Prior art date
Application number
MA31650A
Other languages
English (en)
Inventor
Thomas Friess
Max Hasmann
Werner Scheuer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37607207&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA30654(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MA30654B1 publication Critical patent/MA30654B1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

La présente invention concerne un procédé de traitement d'un patient souffrant d'une rechute d'un cancer positif à HER2, avec un anticorps anti-VEGF pendant ou après un traitement avec un anticorps anti-HER2. L'invention concerne également des articles manufacturés correspondants.
MA31650A 2006-08-21 2009-02-19 Therapie tumorale avec anticorps anti-vegf MA30654B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06017330 2006-08-21

Publications (1)

Publication Number Publication Date
MA30654B1 true MA30654B1 (fr) 2009-08-03

Family

ID=37607207

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31650A MA30654B1 (fr) 2006-08-21 2009-02-19 Therapie tumorale avec anticorps anti-vegf

Country Status (28)

Country Link
US (6) US20080050385A1 (fr)
EP (2) EP2441472B1 (fr)
JP (3) JP2010501498A (fr)
KR (1) KR101136763B1 (fr)
CN (1) CN101505792B (fr)
AR (1) AR062419A1 (fr)
AU (1) AU2007287794B2 (fr)
BR (1) BRPI0715829A2 (fr)
CA (1) CA2660681A1 (fr)
CL (1) CL2007002404A1 (fr)
CO (1) CO6150193A2 (fr)
CR (1) CR10590A (fr)
DK (1) DK2056874T3 (fr)
ES (2) ES2392630T3 (fr)
IL (2) IL196810A0 (fr)
MA (1) MA30654B1 (fr)
MX (1) MX2009001715A (fr)
MY (1) MY150756A (fr)
NO (1) NO20090450L (fr)
NZ (1) NZ574580A (fr)
PE (1) PE20080911A1 (fr)
PL (1) PL2056874T3 (fr)
RU (1) RU2528884C2 (fr)
SG (1) SG174090A1 (fr)
SI (1) SI2056874T1 (fr)
TW (2) TW201107346A (fr)
WO (1) WO2008022746A1 (fr)
ZA (1) ZA200901200B (fr)

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WO2006063042A2 (fr) * 2004-12-07 2006-06-15 Genentech, Inc. Selection de patients pour une therapie avec un inhibiteur de her
RU2438705C2 (ru) 2005-01-21 2012-01-10 Дженентек, Инк. Введение фиксированных доз her-антител
CA2596133C (fr) 2005-02-23 2016-11-15 Genentech, Inc. Retardement de la progression de la maladie ou survie des patients atteints du cancer
PE20070207A1 (es) * 2005-07-22 2007-03-09 Genentech Inc Tratamiento combinado de los tumores que expresan el her
ES2392630T3 (es) * 2006-08-21 2012-12-12 F. Hoffmann-La Roche Ag Terapia antitumoral con anticuerpos anti-VEGF
AU2008223069B2 (en) 2007-03-02 2012-12-13 F. Hoffmann-La Roche Ag Predicting response to a HER dimerisation inhibitor based on low HER3 expression
TWI472339B (zh) 2008-01-30 2015-02-11 Genentech Inc 包含結合至her2結構域ii之抗體及其酸性變異體的組合物
BRPI0812682A2 (pt) 2008-06-16 2010-06-22 Genentech Inc tratamento de cáncer de mama metastático
JP6320753B2 (ja) 2010-05-27 2018-05-09 ゲンマブ エー/エス Her2に対するモノクローナル抗体
WO2011147982A2 (fr) 2010-05-27 2011-12-01 Genmab A/S Anticorps monoclonaux contre l'épitope de her2
AU2011281700B2 (en) * 2010-07-19 2017-02-09 F. Hoffmann-La Roche Ag Blood plasma biomarkers for bevacizumab combination therapies for treatment of pancreatic cancer
BR112013004012B1 (pt) * 2010-08-20 2021-03-23 Novartis Ag Anticorpo monoclonal isolado ou fragmento de ligação ao antígeno do mesmo ao receptor her3, seu uso e composição farmacêutica
AU2012245116A1 (en) 2011-04-20 2013-11-07 Genmab A/S Bispecific antibodies against HER2 and CD3
CN104334189A (zh) 2011-10-14 2015-02-04 霍夫曼-拉罗奇有限公司 Her2二聚化抑制剂帕妥珠单抗的用途和包含her2二聚化抑制剂帕妥珠单抗的制品
AU2012348600A1 (en) * 2011-12-05 2014-05-22 F. Hoffmann-La Roche Ag Blood plasma biomarkers for bevacizumab combination therapies for treatment of breast cancer
WO2013148159A1 (fr) * 2012-03-30 2013-10-03 Fibrogen Inc Procédés thérapeutiques pour une carcinomatose péritonéale
CA2907776C (fr) 2013-04-16 2020-04-14 Genentech, Inc. Variantes de pertuzumab et leur evaluation
AU2015249633B2 (en) 2014-04-25 2020-10-15 Genentech, Inc. Methods of treating early breast cancer with Trastuzumab-MCC-DM1 and Pertuzumab
TW201619200A (zh) * 2014-10-10 2016-06-01 麥迪紐有限責任公司 人類化抗-ox40抗體及其用途
DK3302551T3 (da) 2015-05-30 2024-08-26 Hoffmann La Roche Fremgangsmåder til behandling af HER2-positiv tidligere ubehandlet metastatisk brystkræft
WO2017087280A1 (fr) 2015-11-16 2017-05-26 Genentech, Inc. Procédés de traitement d'un cancer positif her2
CN106729743B (zh) 2015-11-23 2021-09-21 四川科伦博泰生物医药股份有限公司 抗ErbB2抗体-药物偶联物及其组合物、制备方法和应用
TW202140776A (zh) 2016-04-26 2021-11-01 美商美國泰福生技股份有限公司 細胞培養基
JP6914336B2 (ja) 2016-12-28 2021-08-04 ジェネンテック, インコーポレイテッド 進行したher2発現がんの治療
EP3868404A1 (fr) 2017-01-17 2021-08-25 F. Hoffmann-La Roche AG Formulations sous-cutanées d'anticorps her2
US11077189B2 (en) 2017-03-02 2021-08-03 Genentech Inc. Adjuvant treatment of HER2-positive breast cancer
CA3059241A1 (fr) 2017-04-24 2018-11-01 Genentech, Inc. Mutations erbb2/her2 dans le domaine transmembranaire ou juxtamembranaire
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Also Published As

Publication number Publication date
AR062419A1 (es) 2008-11-05
US20080050385A1 (en) 2008-02-28
AU2007287794B2 (en) 2013-03-28
KR20090032136A (ko) 2009-03-31
ES2546066T3 (es) 2015-09-18
HK1134441A1 (en) 2010-04-30
CA2660681A1 (fr) 2008-02-28
MX2009001715A (es) 2009-02-25
US20110223159A1 (en) 2011-09-15
JP2010501498A (ja) 2010-01-21
IL238045A0 (en) 2015-05-31
CN101505792B (zh) 2012-10-03
NZ574580A (en) 2011-12-22
KR101136763B1 (ko) 2012-04-24
ES2392630T3 (es) 2012-12-12
CN101505792A (zh) 2009-08-12
US20180251536A1 (en) 2018-09-06
DK2056874T3 (da) 2012-10-15
PL2056874T3 (pl) 2013-02-28
US20150239969A1 (en) 2015-08-27
EP2441472B1 (fr) 2015-06-10
MY150756A (en) 2014-02-28
CR10590A (es) 2009-03-20
SG174090A1 (en) 2011-09-29
WO2008022746A1 (fr) 2008-02-28
US20130183292A1 (en) 2013-07-18
JP2013163687A (ja) 2013-08-22
BRPI0715829A2 (pt) 2013-07-23
JP2015214582A (ja) 2015-12-03
AU2007287794A1 (en) 2008-02-28
NO20090450L (no) 2009-02-27
EP2056874A1 (fr) 2009-05-13
TW201107346A (en) 2011-03-01
SI2056874T1 (sl) 2012-12-31
RU2009110102A (ru) 2010-09-27
CL2007002404A1 (es) 2008-04-18
RU2528884C2 (ru) 2014-09-20
US20100285010A1 (en) 2010-11-11
PE20080911A1 (es) 2008-08-15
EP2056874B1 (fr) 2012-09-19
ZA200901200B (en) 2013-08-28
CO6150193A2 (es) 2010-04-20
IL196810A0 (en) 2011-08-01
TW200825106A (en) 2008-06-16
EP2441472A1 (fr) 2012-04-18

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