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CR8698A - Anticuerpos monoclonales al factor de crecimiento de hepatocito - Google Patents

Anticuerpos monoclonales al factor de crecimiento de hepatocito

Info

Publication number
CR8698A
CR8698A CR8698A CR8698A CR8698A CR 8698 A CR8698 A CR 8698A CR 8698 A CR8698 A CR 8698A CR 8698 A CR8698 A CR 8698A CR 8698 A CR8698 A CR 8698A
Authority
CR
Costa Rica
Prior art keywords
growth factor
hepatocite
monoclonal antibodies
pharmaceutical composition
administering
Prior art date
Application number
CR8698A
Other languages
English (en)
Inventor
Kyung Jin Kim
Yi-Chi Su
Original Assignee
Galaxy Biotech Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35320045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR8698(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Galaxy Biotech Llc filed Critical Galaxy Biotech Llc
Publication of CR8698A publication Critical patent/CR8698A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • G01N2333/4753Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invencion es concerniente con un anticuerpo monoclonal neutralizante al factor crecimiento de hepatocito, una composicion farmaceutica que comprende el mismo y metodo de tratamiento que comprenden administrar tal composicion farmaceutica a un paciente, tal como para inhibir glioblastoma.
CR8698A 2004-04-15 2006-10-19 Anticuerpos monoclonales al factor de crecimiento de hepatocito CR8698A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/825,060 US20040208876A1 (en) 2003-04-18 2004-04-15 Monoclonal antibodies to hepatocyte growth factor

Publications (1)

Publication Number Publication Date
CR8698A true CR8698A (es) 2007-12-17

Family

ID=35320045

Family Applications (1)

Application Number Title Priority Date Filing Date
CR8698A CR8698A (es) 2004-04-15 2006-10-19 Anticuerpos monoclonales al factor de crecimiento de hepatocito

Country Status (25)

Country Link
US (5) US20040208876A1 (es)
EP (2) EP2204191A1 (es)
JP (2) JP4594381B2 (es)
KR (1) KR101072736B1 (es)
CN (1) CN1964738A (es)
AT (1) ATE473760T1 (es)
AU (1) AU2004319276C1 (es)
BR (1) BRPI0418745A (es)
CA (1) CA2563080C (es)
CR (1) CR8698A (es)
CY (1) CY1110783T1 (es)
DE (1) DE602004028168D1 (es)
DK (1) DK1734995T3 (es)
ES (1) ES2346886T3 (es)
HR (1) HRP20100521T1 (es)
IL (1) IL178474A (es)
MX (1) MXPA06011822A (es)
NO (1) NO20065227L (es)
NZ (1) NZ550324A (es)
PL (1) PL1734995T3 (es)
PT (1) PT1734995E (es)
RU (1) RU2361879C2 (es)
SI (1) SI1734995T1 (es)
WO (1) WO2005107800A1 (es)
ZA (1) ZA200609407B (es)

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US20040208876A1 (en) * 2003-04-18 2004-10-21 Kim Kyung Jin Monoclonal antibodies to hepatocyte growth factor
AR042955A1 (es) * 2003-07-18 2005-07-13 Amgen Inc Agentes de union especifica al factor de crecimiento de hepatocitos
RU2398777C2 (ru) * 2004-08-05 2010-09-10 Дженентек, Инк. ГУМАНИЗИРОВАННЫЕ АНТАГОНИСТЫ, НАПРАВЛЕННЫЕ ПРОТИВ c-met
US20070036797A1 (en) * 2005-06-02 2007-02-15 Galaxy Biotech, Llc Methods of treating brain tumors with antibodies
WO2007043641A1 (ja) 2005-10-14 2007-04-19 Fukuoka University 膵島移植における移植膵島障害抑制剤
RU2450830C2 (ru) 2005-10-21 2012-05-20 Чугаи Сейяку Кабусики Кайся Средства для лечения кардиопатии
AR057582A1 (es) 2005-11-15 2007-12-05 Nat Hospital Organization Agentes para suprimir la induccion de linfocitos t citotoxicos
KR20080084818A (ko) * 2005-11-25 2008-09-19 각고호우징 게이오기주크 전립선암 치료제
EP3135298B1 (en) 2006-01-27 2018-06-06 Keio University Therapeutic agents for diseases involving choroidal neovascularization
AR059922A1 (es) * 2006-04-01 2008-05-07 Galaxy Biotech Llc Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos
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NO345476B1 (no) 2006-06-02 2021-02-22 Xoma Technology Ltd Bindingsproteiner for hepatocyttvekstfaktor (HGF)
ES2378097T3 (es) * 2006-06-02 2012-04-04 Aveo Pharmaceuticals, Inc. Proteínas de unión al factor de crecimiento de hepatocitos (HGF)
AU2008208321B2 (en) 2007-01-23 2013-03-21 Chugai Seiyaku Kabushiki Kaisha Chronic rejection inhibitor
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TW201002346A (en) * 2008-04-11 2010-01-16 Galaxy Biotech Llc Combination of HGF inhibitor and EGF inhibitor to treat cancer
EP2288383A1 (en) * 2008-05-14 2011-03-02 Amgen, Inc Combinations vegf(r) inhibitors and hepatocyte growth factor (c-met) inhibitors for the treatment of cancer
CN102256623A (zh) 2008-06-05 2011-11-23 独立行政法人国立癌症研究中心 神经浸润抑制剂
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Also Published As

Publication number Publication date
CA2563080C (en) 2015-01-27
HK1094167A1 (en) 2007-03-23
EP1734995A4 (en) 2007-04-25
JP2011012067A (ja) 2011-01-20
US7687063B2 (en) 2010-03-30
CA2563080A1 (en) 2005-11-17
CN1964738A (zh) 2007-05-16
US20090104192A1 (en) 2009-04-23
SI1734995T1 (sl) 2010-09-30
RU2006140257A (ru) 2008-05-20
KR20070012711A (ko) 2007-01-26
ES2346886T3 (es) 2010-10-21
AU2004319276C1 (en) 2011-03-03
IL178474A (en) 2011-04-28
PL1734995T3 (pl) 2010-12-31
PT1734995E (pt) 2010-08-18
US7494650B2 (en) 2009-02-24
EP1734995B1 (en) 2010-07-14
RU2361879C2 (ru) 2009-07-20
US20040208876A1 (en) 2004-10-21
JP4594381B2 (ja) 2010-12-08
EP1734995A1 (en) 2006-12-27
HRP20100521T1 (hr) 2010-10-31
IL178474A0 (en) 2007-02-11
KR101072736B1 (ko) 2011-10-11
NZ550324A (en) 2009-12-24
DK1734995T3 (da) 2010-10-25
AU2004319276A1 (en) 2005-11-17
NO20065227L (no) 2007-01-10
MXPA06011822A (es) 2007-03-23
US20120064066A1 (en) 2012-03-15
WO2005107800A1 (en) 2005-11-17
JP2007532643A (ja) 2007-11-15
EP2204191A1 (en) 2010-07-07
DE602004028168D1 (de) 2010-08-26
US20070160613A1 (en) 2007-07-12
ATE473760T1 (de) 2010-07-15
CY1110783T1 (el) 2015-06-10
BRPI0418745A (pt) 2007-12-11
AU2004319276B2 (en) 2010-08-26
ZA200609407B (en) 2008-07-30
US20080019966A1 (en) 2008-01-24

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