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MA29943B1 - Derives de pyrazolo[4,3-d] pyrimidine-5-yle utilises comme inhibiteurs de pde5 - Google Patents

Derives de pyrazolo[4,3-d] pyrimidine-5-yle utilises comme inhibiteurs de pde5

Info

Publication number
MA29943B1
MA29943B1 MA30918A MA30918A MA29943B1 MA 29943 B1 MA29943 B1 MA 29943B1 MA 30918 A MA30918 A MA 30918A MA 30918 A MA30918 A MA 30918A MA 29943 B1 MA29943 B1 MA 29943B1
Authority
MA
Morocco
Prior art keywords
pyrazolo
yle
pyrimidine
derivatives
formula
Prior art date
Application number
MA30918A
Other languages
English (en)
Inventor
Michael Brent Tollefson
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of MA29943B1 publication Critical patent/MA29943B1/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract

LA PRÉSENTE INVENTION CONCERNE UN ACIDE 1-(1-(2-ÉTHOXYÉTHYL-3-ÉTHYL-7-(4-MÉTHYLPYRIDIN-2- YLAMINO)-LH-PYRAZOLO[4,3-D]PYRIMIDIN-5-YL)PIPÉRIDINE 4-CARBOXYLIQUE REPRÉSENTÉ PAR LA FORMULE (I) ET SES SELS. L'INVENTION CONCERNE ÉGALEMENT DES COMPOSITIONS PHARMACEUTIQUES, DES MÉTHODES DE TRAITEMENT ET DES PROCÉDÉS DE SYNTHÈSE CONCERNANT LA FORMULE (I). L'ACIDE REPRÉSENTÉ PAR LA FORMULE (I) ET SES SELS S'UTILISENT POUR INHIBER L'ENZYME PDE5.
MA30918A 2005-11-10 2008-05-09 Derives de pyrazolo[4,3-d] pyrimidine-5-yle utilises comme inhibiteurs de pde5 MA29943B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73532005P 2005-11-10 2005-11-10

Publications (1)

Publication Number Publication Date
MA29943B1 true MA29943B1 (fr) 2008-11-03

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Family Applications (1)

Application Number Title Priority Date Filing Date
MA30918A MA29943B1 (fr) 2005-11-10 2008-05-09 Derives de pyrazolo[4,3-d] pyrimidine-5-yle utilises comme inhibiteurs de pde5

Country Status (29)

Country Link
US (2) US20090156618A1 (fr)
EP (1) EP1948661B1 (fr)
JP (1) JP4208959B1 (fr)
KR (1) KR101012592B1 (fr)
CN (1) CN101305007B (fr)
AP (1) AP2008004437A0 (fr)
AR (1) AR057885A1 (fr)
AT (1) ATE435865T1 (fr)
AU (1) AU2006313486B2 (fr)
BR (1) BRPI0618284A2 (fr)
CA (1) CA2629339C (fr)
CR (1) CR9966A (fr)
DE (1) DE602006007728D1 (fr)
DK (1) DK1948661T3 (fr)
DO (1) DOP2006000248A (fr)
EA (1) EA200800920A1 (fr)
EC (1) ECSP088441A (fr)
ES (1) ES2326919T3 (fr)
IL (1) IL190456A (fr)
MA (1) MA29943B1 (fr)
NL (1) NL2000291C2 (fr)
NO (1) NO20082593L (fr)
PE (1) PE20070764A1 (fr)
RS (1) RS20080197A (fr)
TN (1) TNSN08209A1 (fr)
TW (1) TW200738723A (fr)
UY (1) UY29909A1 (fr)
WO (1) WO2007054778A1 (fr)
ZA (1) ZA200803173B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0916931A2 (pt) * 2008-08-01 2015-11-24 Biocryst Pharm Inc agentes terapêuticos
WO2010043633A1 (fr) * 2008-10-15 2010-04-22 Palau Pharma, S. A. Dérivés de 2h-pyrazolo[4,3-d]pyrimidin-5-amine utilisés comme antagonistes des récepteurs h4 de l'histamine pour le traitement de maladies allergiques, immunologiques et inflammatoires
EP2556820A4 (fr) * 2010-04-05 2015-01-21 Sk Chemicals Co Ltd Composition contenant un inhibiteur de pde5 pour l'atténuation des rides de la peau
EP2682128B1 (fr) * 2011-02-28 2017-11-08 National Cerebral and Cardiovascular Center Peptide natriurétique auriculaire ou peptide cérébral natriurétique pour le prévention de la métastase
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