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MA29686B1 - Sels de 4-methyl-n-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3- (4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide - Google Patents

Sels de 4-methyl-n-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3- (4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide

Info

Publication number
MA29686B1
MA29686B1 MA30563A MA30563A MA29686B1 MA 29686 B1 MA29686 B1 MA 29686B1 MA 30563 A MA30563 A MA 30563A MA 30563 A MA30563 A MA 30563A MA 29686 B1 MA29686 B1 MA 29686B1
Authority
MA
Morocco
Prior art keywords
methyl
ylamino
imidazol
pyrimidin
pyridin
Prior art date
Application number
MA30563A
Other languages
English (en)
Inventor
Paul W Manley
Wen-Chung Shieh
Paul Allen Sutton
Piotr H Karpinski
Raeann Wu
Stephanie Monnier
Joerg Brozio
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37398525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA29686(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA29686B1 publication Critical patent/MA29686B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Sels de 4-méthyl-N-[3-(4-méthyl-imidazol-1-yl)-5-trifluorométhyl-phényl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide préparés à l'aide de divers procédés.
MA30563A 2005-07-20 2008-01-09 Sels de 4-methyl-n-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3- (4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide MA29686B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70140605P 2005-07-20 2005-07-20
US71621305P 2005-09-12 2005-09-12

Publications (1)

Publication Number Publication Date
MA29686B1 true MA29686B1 (fr) 2008-08-01

Family

ID=37398525

Family Applications (1)

Application Number Title Priority Date Filing Date
MA30563A MA29686B1 (fr) 2005-07-20 2008-01-09 Sels de 4-methyl-n-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3- (4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide

Country Status (33)

Country Link
US (4) US8163904B2 (fr)
EP (2) EP2186808B1 (fr)
JP (1) JP5129132B2 (fr)
KR (3) KR20140047737A (fr)
CN (1) CN102267981A (fr)
AR (1) AR057467A1 (fr)
AT (1) ATE514689T1 (fr)
AU (2) AU2006276205C1 (fr)
BR (1) BRPI0613605A2 (fr)
CA (2) CA2615669C (fr)
CY (1) CY1111772T1 (fr)
DK (1) DK1910336T3 (fr)
EC (1) ECSP088118A (fr)
ES (1) ES2634291T3 (fr)
GT (1) GT200600316A (fr)
HR (1) HRP20110639T1 (fr)
IL (1) IL187787A (fr)
JO (1) JO2757B1 (fr)
MA (1) MA29686B1 (fr)
MX (1) MX2008000892A (fr)
MY (1) MY149889A (fr)
NO (1) NO341313B1 (fr)
NZ (2) NZ591142A (fr)
PE (1) PE20070241A1 (fr)
PL (1) PL1910336T3 (fr)
PT (1) PT1910336E (fr)
RU (4) RU2483065C2 (fr)
SG (1) SG170772A1 (fr)
SI (1) SI1910336T1 (fr)
TN (1) TNSN08028A1 (fr)
TW (1) TWI455934B (fr)
UY (1) UY29683A1 (fr)
WO (1) WO2007015871A1 (fr)

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AR086913A1 (es) 2011-06-14 2014-01-29 Novartis Ag 4-metil-3-[[4-(3-piridinil)-2-pirimidinil]-amino]-n-[5-(4-metil-1h-imidazol-1-il)-3-(trifluoro-metil)-fenil]-benzamida amorfa, forma de dosificacion que la contiene y metodo para prepararlas
WO2013063003A1 (fr) 2011-10-28 2013-05-02 Novartis Ag Méthode de traitement des tumeurs stromales gastro-intestinales
PH12014500897A1 (en) 2011-10-28 2019-10-07 Novartis Ag Method of treating gastrointestinal stromal tumors
AR088844A1 (es) 2011-11-14 2014-07-10 Novartis Ag Formulacion de liberacion inmediata de 4-metil-3-[[4-(3-piridinil)-2-pirimidinil]-amino]-n-[5-(4-metil-1h-imidazol-1-il)-3-(trifluoro-metil)-fenil]-benzamida
BR112015000349A2 (pt) 2012-07-11 2017-06-27 Novartis Ag método de tratamento de tumores estromais gastrointestinais
EP2906554A4 (fr) * 2012-10-15 2016-06-29 Apotex Inc Formes solides du chlorhydrate de nilotinib
US9567317B2 (en) 2012-10-19 2017-02-14 Basf Se Multicomponent crystalline system comprising nilotinib and selected co-crystal formers
EP2792360A1 (fr) 2013-04-18 2014-10-22 IP Gesellschaft für Management mbH (1aR,12bS)-8-cyclohexyl-11-fluoro-N-((1-methylcyclopropyl)sulfonyl)-1a-((3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl)-1,1a,2,2b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide pour utilisation dans le traitement de HCV
CA2912902A1 (fr) 2013-04-24 2014-10-30 Dr. Reddy's Laboratories Limited Formes polymorphiques de chlorhydrate de nilotinib
RU2551359C9 (ru) * 2013-11-28 2021-08-20 Общество с ограниченной ответственностью "Мамонт Фарм" Наноразмерная слабо закристаллизованная модификация 4-метил-N-[3-(4-метилимидазол-1-ил)-5-(трифторметил)фенил]-3-[(4-пиридин-3-илпиримидин-2-ил)амино]бензамида гидрохлорида моногидрата, способ ее получения и фармацевтическая композиция на ее основе
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CN112423757A (zh) * 2018-06-15 2021-02-26 汉达生技医药责任有限公司 激酶抑制剂的盐类及其组合物
WO2020095187A1 (fr) * 2018-11-05 2020-05-14 Laurus Labs Limited Forme cristalline de chlorhydrate de nilotinib, son procédé de préparation et composition pharmaceutique le contenant
ES2993251T3 (en) 2019-02-18 2024-12-26 Slayback Pharma Llc Pharmaceutical compositions of nilotinib
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EP4103560A1 (fr) * 2020-02-15 2022-12-21 Cipla Limited Nouveaux sels de nilotinib et formes polymorphes de celui-ci
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Also Published As

Publication number Publication date
CN102267981A (zh) 2011-12-07
RU2011120363A (ru) 2012-11-27
CA2615669C (fr) 2013-11-12
AU2010241419B2 (en) 2012-03-29
KR101755137B1 (ko) 2017-07-06
GT200600316A (es) 2007-04-02
SG170772A1 (en) 2011-05-30
US20120270891A1 (en) 2012-10-25
PL1910336T3 (pl) 2011-11-30
CA2823946C (fr) 2015-12-29
IL187787A (en) 2012-07-31
US8580806B2 (en) 2013-11-12
CA2615669A1 (fr) 2007-02-08
US8163904B2 (en) 2012-04-24
MX2008000892A (es) 2008-03-18
RU2483065C2 (ru) 2013-05-27
MY149889A (en) 2013-10-31
CY1111772T1 (el) 2015-10-07
KR20140047737A (ko) 2014-04-22
RU2434864C2 (ru) 2011-11-27
RU2605551C2 (ru) 2016-12-20
PE20070241A1 (es) 2007-03-22
RU2013101749A (ru) 2014-07-27
JO2757B1 (en) 2014-03-15
EP2186808B1 (fr) 2017-04-19
US9163005B2 (en) 2015-10-20
TNSN08028A1 (en) 2009-07-14
AU2010241419C1 (en) 2024-05-23
TW200800950A (en) 2008-01-01
EP1910336A1 (fr) 2008-04-16
WO2007015871A1 (fr) 2007-02-08
NZ564182A (en) 2011-03-31
US20080200487A1 (en) 2008-08-21
AR057467A1 (es) 2007-12-05
NZ591142A (en) 2012-09-28
AU2010241419A1 (en) 2010-12-02
RU2008105827A (ru) 2009-08-27
CA2823946A1 (fr) 2007-02-08
ECSP088118A (es) 2008-02-20
TWI455934B (zh) 2014-10-11
RU2509767C1 (ru) 2014-03-20
NO341313B1 (no) 2017-10-09
PT1910336E (pt) 2011-09-05
EP2186808A1 (fr) 2010-05-19
HK1116778A1 (en) 2009-01-02
ATE514689T1 (de) 2011-07-15
NO20080897L (no) 2008-02-20
KR20080027855A (ko) 2008-03-28
BRPI0613605A2 (pt) 2011-01-18
US8389537B2 (en) 2013-03-05
HRP20110639T1 (hr) 2011-10-31
US20140038994A1 (en) 2014-02-06
JP2009502796A (ja) 2009-01-29
AU2006276205A1 (en) 2007-02-08
SI1910336T1 (sl) 2011-10-28
DK1910336T3 (da) 2011-10-03
US20130137712A1 (en) 2013-05-30
JP5129132B2 (ja) 2013-01-23
IL187787A0 (en) 2008-08-07
AU2006276205B2 (en) 2010-08-19
KR20150100946A (ko) 2015-09-02
EP1910336B1 (fr) 2011-06-29
UY29683A1 (es) 2007-02-28
AU2006276205C1 (en) 2024-08-01
ES2634291T3 (es) 2017-09-27

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