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MA26425A1 - Derives de lactames, procede pour leur preparation et compositions pharmaceutiques les contenant - Google Patents

Derives de lactames, procede pour leur preparation et compositions pharmaceutiques les contenant

Info

Publication number
MA26425A1
MA26425A1 MA24535A MA24535A MA26425A1 MA 26425 A1 MA26425 A1 MA 26425A1 MA 24535 A MA24535 A MA 24535A MA 24535 A MA24535 A MA 24535A MA 26425 A1 MA26425 A1 MA 26425A1
Authority
MA
Morocco
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
lactam derivatives
lactam
Prior art date
Application number
MA24535A
Other languages
English (en)
Inventor
R Howard Harry
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MA26425A1 publication Critical patent/MA26425A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/382-Pyrrolones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • C07D211/76Oxygen atoms attached in position 2 or 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
MA24535A 1996-03-29 1997-03-26 Derives de lactames, procede pour leur preparation et compositions pharmaceutiques les contenant MA26425A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1513496P 1996-03-29 1996-03-29

Publications (1)

Publication Number Publication Date
MA26425A1 true MA26425A1 (fr) 2004-12-20

Family

ID=21769713

Family Applications (1)

Application Number Title Priority Date Filing Date
MA24535A MA26425A1 (fr) 1996-03-29 1997-03-26 Derives de lactames, procede pour leur preparation et compositions pharmaceutiques les contenant

Country Status (39)

Country Link
US (2) US6462048B2 (fr)
EP (1) EP0894085B1 (fr)
JP (1) JP3118467B2 (fr)
KR (1) KR100305071B1 (fr)
CN (1) CN1128788C (fr)
AP (1) AP824A (fr)
AR (1) AR006390A1 (fr)
AT (1) ATE302182T1 (fr)
AU (1) AU706839B2 (fr)
BG (1) BG64176B1 (fr)
BR (1) BR9708581A (fr)
CA (1) CA2249603A1 (fr)
CO (1) CO4650033A1 (fr)
CZ (1) CZ293628B6 (fr)
DE (1) DE69733996T2 (fr)
DZ (1) DZ2198A1 (fr)
EA (1) EA001485B1 (fr)
ES (1) ES2246058T3 (fr)
HN (1) HN1997000023A (fr)
HR (1) HRP970175A2 (fr)
HU (1) HUP9902160A3 (fr)
ID (1) ID17781A (fr)
IL (1) IL125377A (fr)
IS (1) IS4813A (fr)
MA (1) MA26425A1 (fr)
MY (1) MY118498A (fr)
NO (1) NO312957B1 (fr)
NZ (1) NZ325914A (fr)
OA (1) OA10879A (fr)
PL (1) PL329170A1 (fr)
SK (1) SK131498A3 (fr)
TN (1) TNSN97056A1 (fr)
TR (1) TR199801929T2 (fr)
TW (1) TW413679B (fr)
UA (1) UA70284C2 (fr)
UY (1) UY24498A1 (fr)
WO (1) WO1997036867A1 (fr)
YU (1) YU11997A (fr)
ZA (1) ZA972690B (fr)

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JPH041367U (fr) * 1990-04-13 1992-01-08
US6147106A (en) 1997-08-20 2000-11-14 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease
US6906093B2 (en) 1995-06-07 2005-06-14 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease
US5880141A (en) * 1995-06-07 1999-03-09 Sugen, Inc. Benzylidene-Z-indoline compounds for the treatment of disease
US6696448B2 (en) 1996-06-05 2004-02-24 Sugen, Inc. 3-(piperazinylbenzylidenyl)-2-indolinone compounds and derivatives as protein tyrosine kinase inhibitors
US6423708B1 (en) * 1996-09-30 2002-07-23 Pfizer Inc Aralkyl and aralkylidene heterocyclic lactams and imides
UA56185C2 (uk) 1996-09-30 2003-05-15 Пфайзер Інк. Аралкіл- та аралкіліденгетероциклічні лактами та іміди, фармацевтична композиція та спосіб лікування
GB9718913D0 (en) 1997-09-05 1997-11-12 Glaxo Group Ltd Substituted oxindole derivatives
US6531502B1 (en) 1998-01-21 2003-03-11 Sugen, Inc. 3-Methylidenyl-2-indolinone modulators of protein kinase
DE19830201A1 (de) * 1998-07-07 2000-01-13 Boehringer Ingelheim Pharma Mittel mit antidepressiver Wirkung
CA2301899C (fr) * 1998-07-27 2008-11-18 Boehringer Ingelheim Pharma Kg Agent antidepresseur
GB9904933D0 (en) 1999-03-04 1999-04-28 Glaxo Group Ltd Compounds
US6492398B1 (en) 1999-03-04 2002-12-10 Smithkline Beechman Corporation Thiazoloindolinone compounds
US6624171B1 (en) 1999-03-04 2003-09-23 Smithkline Beecham Corporation Substituted aza-oxindole derivatives
ES2225031T3 (es) * 1999-12-29 2005-03-16 Pfizer Products Inc. Compuestos de 3-((2-piperazinil-fenil)metil)-1-(4-(trifluorometil)fenil)-2-pirrolidinona opticamente activos como antagonistas selectivos del receptor de 5-ht1d.
SK287142B6 (sk) 2000-02-15 2010-01-07 Sugen, Inc. Inhibítory proteínkináz na báze pyrolom substituovaného 2-indolinónu, farmaceutický prípravok s ich obsahom a ich použitie
US6620818B1 (en) 2000-03-01 2003-09-16 Smithkline Beecham Corporation Method for reducing the severity of side effects of chemotherapy and/or radiation therapy
AR042586A1 (es) 2001-02-15 2005-06-29 Sugen Inc 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa
WO2003031438A1 (fr) 2001-10-10 2003-04-17 Sugen, Inc. Derives de 3-[4-(substitue heterocyclyl)-pyrrol-2-ylmethylidene]-2-indolinone utiles comme inhibiteurs des kinases
TW200301701A (en) * 2002-01-02 2003-07-16 Ardent Pharmaceuticals Inc Method of treating sexual dysfunctions with delta opioid receptor agonist compounds
TWI263497B (en) * 2002-03-29 2006-10-11 Lilly Co Eli Pyridinoylpiperidines as 5-HT1F agonists
DE602004028150D1 (de) * 2003-11-26 2010-08-26 Pfizer Prod Inc Aminopyrazolderivate als gsk-3-inhibitoren
BRPI0507190A (pt) * 2004-01-29 2007-06-26 Pfizer Prod Inc combinação de moduladores do ácido gama-aminobutìrico e antagonistas de 5-ht1b receptores
ES2374629T3 (es) * 2004-03-17 2012-02-20 Pfizer Products Incorporated Nuevos derivados de bencil(iden)-lactama.
BRPI0510942A (pt) * 2004-05-11 2007-07-17 Pfizer Prod Inc combinação de antipsicóticos atìpicos e antagonistas do receptor 5-ht1b
EP1753745A2 (fr) * 2004-05-21 2007-02-21 Pfizer Products Inc. Derives pyrazinylmethyle-lactame
JP2008503559A (ja) * 2004-06-25 2008-02-07 ファイザー・プロダクツ・インク Cns障害を治療するためのピリジルピペラジン
ATE521591T1 (de) * 2005-01-13 2011-09-15 Ge Healthcare Ltd 11c-markierte benzyl-lactam-verbindungen und deren verwendung als bildgebungsmittel
WO2006106416A1 (fr) * 2005-04-08 2006-10-12 Pfizer Products Inc. Pyridil-lactams et leur utilisation comme ligands de recepteurs 5-ht1
CA2612268A1 (fr) * 2005-06-17 2006-12-28 Pfizer Products Inc. Metabolites de 1-[6-(1-ethyl-1-hydroxy-propyl)-pyridin-3-yl]-3-[2-(4-methyl-piperazin-1-yl)-benzyl]-pyrrolidin-2-one utilises en tant qu'antagonistes du recepteur de serotonine
WO2007012964A1 (fr) * 2005-07-25 2007-02-01 Pfizer Products Inc. Préparation de composés d'alkylpipérazinylphényle par dédoublement classique
WO2007026219A2 (fr) * 2005-08-31 2007-03-08 Pfizer Products Inc. Composition d'antagonistes du recepteur 5-ht1b servant au traitement d'etats du systeme nerveux central
WO2007026224A2 (fr) * 2005-08-31 2007-03-08 Pfizer Products Inc. Composition d'antagoniste 5-ht1b pour le traitement de la depression, de l'anxiete et des troubles de la cognition
US20070096411A1 (en) * 2005-11-02 2007-05-03 Rempe Gary L Ii Device for retaining a kneeling rider on a gliding board
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物
CN114773318A (zh) * 2015-09-02 2022-07-22 特维娜有限公司 含有六元氮杂杂环的δ阿片受体调节化合物、其使用和制备方法
WO2018152286A1 (fr) 2017-02-17 2018-08-23 Trevena, Inc. Composés modulateurs du récepteur des opioïdes delta contenant des hétérocycles aza à 7 chaînons, et leurs procédés de préparation et d'utilisation
KR20190129867A (ko) 2017-02-17 2019-11-20 트레베나, 인코포레이티드. 5-원 아자-헤테로고리 함유 델타-오피오이드 수용체 조절 화합물, 및 그의 사용 및 제조 방법
WO2020183011A1 (fr) 2019-03-14 2020-09-17 Institut Curie Inhibiteurs de htr1d et leurs utilisations dans le traitement du cancer

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US4078062A (en) 1976-10-28 1978-03-07 E. R. Squibb & Sons, Inc. Substituted 2H-1,4-benzothiazin-3(4H)-ones
JPS62116557A (ja) 1985-11-15 1987-05-28 Takeda Chem Ind Ltd 置換ベンジルラクタム類
US5189179A (en) * 1990-08-29 1993-02-23 Merrell Dow Pharmaceuticals Inc. Serotonin 5ht1a agonists
DK0533268T3 (da) 1991-09-18 2001-12-03 Glaxo Group Ltd Benzanilidderivater som 5HT-1D antagonister
CA2120925A1 (fr) * 1991-10-11 1993-04-15 Patrick Yuk-Sun Lam Composes carbonyles cycliques substitues et leurs derives utilises comme inhibiteurs de la protease retrovirale
US5436246A (en) * 1992-09-17 1995-07-25 Merrell Dow Pharmaceuticals Inc. Serotonin receptor agents
GB9410512D0 (en) * 1994-05-25 1994-07-13 Smithkline Beecham Plc Novel treatment
US5880141A (en) * 1995-06-07 1999-03-09 Sugen, Inc. Benzylidene-Z-indoline compounds for the treatment of disease
US6467084B1 (en) * 1999-12-16 2002-10-15 Emware, Inc. Systems and methods for reprogramming an embedded device with program code using relocatable program code

Also Published As

Publication number Publication date
NZ325914A (en) 1999-09-29
AU706839B2 (en) 1999-06-24
UY24498A1 (es) 2000-09-29
US6462048B2 (en) 2002-10-08
ATE302182T1 (de) 2005-09-15
US6924289B2 (en) 2005-08-02
EP0894085A1 (fr) 1999-02-03
AP9700955A0 (en) 1997-04-30
WO1997036867A1 (fr) 1997-10-09
TW413679B (en) 2000-12-01
ZA972690B (en) 1998-09-28
EA001485B1 (ru) 2001-04-23
US20020028821A1 (en) 2002-03-07
IL125377A0 (en) 1999-03-12
MY118498A (en) 2004-11-30
NO984513L (no) 1998-09-28
CA2249603A1 (fr) 1997-10-09
EP0894085B1 (fr) 2005-08-17
IS4813A (is) 1998-07-29
BR9708581A (pt) 1999-08-03
DE69733996T2 (de) 2006-07-20
CN1128788C (zh) 2003-11-26
JPH11506472A (ja) 1999-06-08
HN1997000023A (es) 1997-06-05
KR100305071B1 (ko) 2001-12-12
KR20000005083A (ko) 2000-01-25
AU1317097A (en) 1997-10-22
UA70284C2 (en) 2004-10-15
DZ2198A1 (fr) 2002-12-02
TR199801929T2 (xx) 1998-12-21
US20030027812A1 (en) 2003-02-06
CZ293628B6 (cs) 2004-06-16
HRP970175A2 (en) 1998-12-31
HK1019446A1 (en) 2000-02-11
JP3118467B2 (ja) 2000-12-18
BG102791A (en) 1999-11-30
AP824A (en) 2000-04-28
NO312957B1 (no) 2002-07-22
YU11997A (sh) 1999-09-27
CZ305298A3 (cs) 1999-07-14
PL329170A1 (en) 1999-03-15
SK131498A3 (en) 2000-09-12
TNSN97056A1 (fr) 2005-03-15
HUP9902160A2 (hu) 1999-11-29
CN1214043A (zh) 1999-04-14
ES2246058T3 (es) 2006-02-01
HUP9902160A3 (en) 2001-02-28
ID17781A (id) 1998-01-29
IL125377A (en) 2005-07-25
OA10879A (en) 2001-10-05
BG64176B1 (bg) 2004-03-31
NO984513D0 (no) 1998-09-28
CO4650033A1 (es) 1998-09-03
AR006390A1 (es) 1999-08-25
DE69733996D1 (de) 2005-09-22
EA199800771A1 (ru) 1999-06-24

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