NO984513L - Benzyl(iden)-laktam-derivater, deres fremstilling og deres anvendelse som selektive (ant)agonister for 5-HT1A- og 5-HT1D-reseptorer - Google Patents

Benzyl(iden)-laktam-derivater, deres fremstilling og deres anvendelse som selektive (ant)agonister for 5-HT1A- og 5-HT1D-reseptorer

Info

Publication number: NO984513L
Authority: NO; Norway
Prior art keywords: ht1a; iden; ant; agonists; benzyl
Prior art date: 1996-03-29

Application number

NO984513A

Other languages

English (en)

Other versions

NO312957B1 (no

NO984513D0 (no

Inventor

Harry R Howard

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-29

Filing date

1998-09-28

Publication date

1998-09-28

1998-09-28 Application filed by Pfizer filed Critical Pfizer

1998-09-28 Publication of NO984513L publication Critical patent/NO984513L/no

1998-09-28 Publication of NO984513D0 publication Critical patent/NO984513D0/no

2002-07-22 Publication of NO312957B1 publication Critical patent/NO312957B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Obesity (AREA)
Hematology (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Child & Adolescent Psychology (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)
Indole Compounds (AREA)
Quinoline Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO19984513A 1996-03-29 1998-09-28 Benzyl(iden)-laktamderivater, anvendelse derav og farmasöytisk sammensetning NO312957B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1513496P	1996-03-29	1996-03-29
PCT/IB1997/000076 WO1997036867A1 (en)	1996-03-29	1997-02-03	Benzyl(idene)-lactam derivatives, their preparation and their use as selective (ant)agonists of 5-ht1a- and/or 5-ht1d receptors

Publications (3)

Publication Number	Publication Date
NO984513L true NO984513L (no)	1998-09-28
NO984513D0 NO984513D0 (no)	1998-09-28
NO312957B1 NO312957B1 (no)	2002-07-22

Family

ID=21769713

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19984513A NO312957B1 (no)	1996-03-29	1998-09-28	Benzyl(iden)-laktamderivater, anvendelse derav og farmasöytisk sammensetning

Country Status (39)

Country	Link
US (2)	US6462048B2 (no)
EP (1)	EP0894085B1 (no)
JP (1)	JP3118467B2 (no)
KR (1)	KR100305071B1 (no)
CN (1)	CN1128788C (no)
AP (1)	AP824A (no)
AR (1)	AR006390A1 (no)
AT (1)	ATE302182T1 (no)
AU (1)	AU706839B2 (no)
BG (1)	BG64176B1 (no)
BR (1)	BR9708581A (no)
CA (1)	CA2249603A1 (no)
CO (1)	CO4650033A1 (no)
CZ (1)	CZ293628B6 (no)
DE (1)	DE69733996T2 (no)
DZ (1)	DZ2198A1 (no)
EA (1)	EA001485B1 (no)
ES (1)	ES2246058T3 (no)
HN (1)	HN1997000023A (no)
HR (1)	HRP970175A2 (no)
HU (1)	HUP9902160A3 (no)
ID (1)	ID17781A (no)
IL (1)	IL125377A (no)
IS (1)	IS4813A (no)
MA (1)	MA26425A1 (no)
MY (1)	MY118498A (no)
NO (1)	NO312957B1 (no)
NZ (1)	NZ325914A (no)
OA (1)	OA10879A (no)
PL (1)	PL329170A1 (no)
SK (1)	SK131498A3 (no)
TN (1)	TNSN97056A1 (no)
TR (1)	TR199801929T2 (no)
TW (1)	TW413679B (no)
UA (1)	UA70284C2 (no)
UY (1)	UY24498A1 (no)
WO (1)	WO1997036867A1 (no)
YU (1)	YU11997A (no)
ZA (1)	ZA972690B (no)

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US6147106A (en)	1997-08-20	2000-11-14	Sugen, Inc.	Indolinone combinatorial libraries and related products and methods for the treatment of disease
US6696448B2 (en) *	1996-06-05	2004-02-24	Sugen, Inc.	3-(piperazinylbenzylidenyl)-2-indolinone compounds and derivatives as protein tyrosine kinase inhibitors
UA56185C2 (uk)	1996-09-30	2003-05-15	Пфайзер Інк.	Аралкіл- та аралкіліденгетероциклічні лактами та іміди, фармацевтична композиція та спосіб лікування
US6423708B1 (en) *	1996-09-30	2002-07-23	Pfizer Inc	Aralkyl and aralkylidene heterocyclic lactams and imides
GB9718913D0 (en)	1997-09-05	1997-11-12	Glaxo Group Ltd	Substituted oxindole derivatives
US6531502B1 (en)	1998-01-21	2003-03-11	Sugen, Inc.	3-Methylidenyl-2-indolinone modulators of protein kinase
DE19830201A1 (de) *	1998-07-07	2000-01-13	Boehringer Ingelheim Pharma	Mittel mit antidepressiver Wirkung
CA2301899C (en) *	1998-07-27	2008-11-18	Boehringer Ingelheim Pharma Kg	Agent with an antidepressant activity
GB9904933D0 (en)	1999-03-04	1999-04-28	Glaxo Group Ltd	Compounds
US6492398B1 (en)	1999-03-04	2002-12-10	Smithkline Beechman Corporation	Thiazoloindolinone compounds
US6624171B1 (en)	1999-03-04	2003-09-23	Smithkline Beecham Corporation	Substituted aza-oxindole derivatives
ATE276249T1 (de) *	1999-12-29	2004-10-15	Pfizer Prod Inc	Optisch aktive 3-((2-piperazinyl-phenyl)methyl)-1-(4-(trifluor methyl)-phenyl)-2-pyrrolidinone als selektive 5-ht1d rezeptor antagonisten
PT1255752E (pt)	2000-02-15	2007-10-17	Pharmacia & Upjohn Co Llc	Inibidores de proteína quinases: 2-indolinonas substituídas com pirrolo
US6620818B1 (en)	2000-03-01	2003-09-16	Smithkline Beecham Corporation	Method for reducing the severity of side effects of chemotherapy and/or radiation therapy
AR042586A1 (es)	2001-02-15	2005-06-29	Sugen Inc	3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa
MXPA04003385A (es)	2001-10-10	2005-04-11	Sugen Inc	Derivados de 3-?4-substituido con heterociclilo)-pirrol-2-ilmetilidene?-2-indolinona como inhibidores de cinasa.
AU2003214800A1 (en)	2002-01-02	2003-07-24	Ardent Pharmaceuticals, Inc.	Method of treating sexual dysfunctions with delta opioid receptor agonist compounds
TWI263497B (en) *	2002-03-29	2006-10-11	Lilly Co Eli	Pyridinoylpiperidines as 5-HT1F agonists
WO2005051919A1 (en) *	2003-11-26	2005-06-09	Pfizer Products Inc.	Aminopyrazole derivatives as gsk-3 inhibitors
EP1737466A1 (en) *	2004-01-29	2007-01-03	Pfizer Products Inc.	COMBINATION OF y-AMINOBUTYRIC ACID MODULATORS AND 5-HT-1b RECEPTOR ANTAGONISTS
KR20060124770A (ko) *	2004-03-17	2006-12-05	화이자 프로덕츠 인코포레이티드	벤질(이덴)-락탐 유도체
CA2565996A1 (en) *	2004-05-11	2005-11-17	Pfizer Products Inc.	Combination of atypical antipsychotics and 5-ht1b receptor antagonists
WO2005113535A2 (en) *	2004-05-21	2005-12-01	Pfizer Products Inc.	Pyrazinylmethyl lactam derivatives
CA2571443A1 (en) *	2004-06-25	2006-01-05	Pfizer Products Inc.	Pyridyl piperazines for the treatment of cns disorders
WO2006075226A1 (en) *	2005-01-13	2006-07-20	Pfizer Products Inc.	11c-labeled benzyl-lactam compounds and their use as imaging agents
WO2006106416A1 (en) *	2005-04-08	2006-10-12	Pfizer Products Inc.	PYRIDIL-LACTAMS AND THEIR USE 5 -HTl RECEPTORS LIGAN
JP2008543829A (ja) *	2005-06-17	2008-12-04	ファイザー・プロダクツ・インク	セロトニン受容体アンタゴニストとしての１−［６−（１−エチル−１−ヒドロキシ−プロピル）−ピリジン−３−イル］−３−［２−（４−メチル−ピペラジン−１−イル）−ベンジル］−ピロリジン−２−オンの代謝産物
WO2007012964A1 (en) *	2005-07-25	2007-02-01	Pfizer Products Inc.	Preparation of alkylpiperazinylphenyl compounds by classical resolution
WO2007026219A2 (en) *	2005-08-31	2007-03-08	Pfizer Products Inc.	Combinations of a 5-ht1b antagonist with a noradrenalin re-uptake inhibitor or a serotonin noradrenalin reutake inhibitor for treating cns conditions
WO2007026224A2 (en) *	2005-08-31	2007-03-08	Pfizer Products Inc.	5-ht1b antagonist composition for depression, anxiety and cognition
US20070096411A1 (en) *	2005-11-02	2007-05-03	Rempe Gary L Ii	Device for retaining a kneeling rider on a gliding board
US20140206667A1 (en)	2012-11-14	2014-07-24	Michela Gallagher	Methods and compositions for treating schizophrenia
US10246436B2 (en) *	2015-09-02	2019-04-02	Trevena, Inc.	6-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same
JP7316216B2 (ja)	2017-02-17	2023-07-27	トレベナ・インコーポレイテッド	５員アザ複素環を含有するデルタ－オピオイド受容体調節化合物、その使用方法及び製造方法
CA3052479A1 (en)	2017-02-17	2018-08-23	Trevena, Inc.	7-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same
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1997
- 1997-02-03 ES ES97900717T patent/ES2246058T3/es not_active Expired - Lifetime
- 1997-02-03 EP EP97900717A patent/EP0894085B1/en not_active Expired - Lifetime
- 1997-02-03 WO PCT/IB1997/000076 patent/WO1997036867A1/en not_active Ceased
- 1997-02-03 CZ CZ19983052A patent/CZ293628B6/cs not_active IP Right Cessation
- 1997-02-03 CN CN97193251A patent/CN1128788C/zh not_active Expired - Fee Related
- 1997-02-03 EA EA199800771A patent/EA001485B1/ru not_active IP Right Cessation
- 1997-02-03 CA CA002249603A patent/CA2249603A1/en not_active Abandoned
- 1997-02-03 IL IL12537797A patent/IL125377A/xx not_active IP Right Cessation
- 1997-02-03 JP JP09535074A patent/JP3118467B2/ja not_active Expired - Fee Related
- 1997-02-03 DE DE69733996T patent/DE69733996T2/de not_active Expired - Fee Related
- 1997-02-03 BR BR9708581A patent/BR9708581A/pt not_active Application Discontinuation
- 1997-02-03 AT AT97900717T patent/ATE302182T1/de not_active IP Right Cessation
- 1997-02-03 AU AU13170/97A patent/AU706839B2/en not_active Ceased
- 1997-02-03 NZ NZ325914A patent/NZ325914A/en unknown
- 1997-02-03 US US09/155,215 patent/US6462048B2/en not_active Expired - Fee Related
- 1997-02-03 TR TR1998/01929T patent/TR199801929T2/xx unknown
- 1997-02-03 HU HU9902160A patent/HUP9902160A3/hu unknown
- 1997-02-03 SK SK1314-98A patent/SK131498A3/sk unknown
- 1997-02-03 PL PL97329170A patent/PL329170A1/xx unknown
- 1997-02-03 KR KR1019980707713A patent/KR100305071B1/ko not_active Expired - Fee Related
- 1997-02-04 TW TW086101295A patent/TW413679B/zh active
- 1997-02-06 HN HN1997000023A patent/HN1997000023A/es unknown
- 1997-03-02 UA UA98095077A patent/UA70284C2/uk unknown
- 1997-03-13 CO CO97013714A patent/CO4650033A1/es unknown
- 1997-03-21 UY UY24498A patent/UY24498A1/es not_active IP Right Cessation
- 1997-03-25 AR ARP970101200A patent/AR006390A1/es not_active Application Discontinuation
- 1997-03-26 HR HR60/015,134A patent/HRP970175A2/hr not_active Application Discontinuation
- 1997-03-26 MA MA24535A patent/MA26425A1/fr unknown
- 1997-03-26 DZ DZ970045A patent/DZ2198A1/fr active
- 1997-03-26 TN TNTNSN97056A patent/TNSN97056A1/fr unknown
- 1997-03-27 ID IDP971025A patent/ID17781A/id unknown
- 1997-03-27 YU YU11997A patent/YU11997A/sh unknown
- 1997-03-27 ZA ZA972690A patent/ZA972690B/xx unknown
- 1997-03-27 AP APAP/P/1997/000955A patent/AP824A/en active
- 1997-03-28 MY MYPI97001340A patent/MY118498A/en unknown
1998
- 1998-07-29 IS IS4813A patent/IS4813A/is unknown
- 1998-09-16 OA OA9800170A patent/OA10879A/en unknown
- 1998-09-24 BG BG102791A patent/BG64176B1/bg unknown
- 1998-09-28 NO NO19984513A patent/NO312957B1/no unknown
2002
- 2002-08-15 US US10/219,692 patent/US6924289B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US20020028821A1 (en)	2002-03-07
CN1128788C (zh)	2003-11-26
TR199801929T2 (xx)	1998-12-21
BR9708581A (pt)	1999-08-03
JPH11506472A (ja)	1999-06-08
NO312957B1 (no)	2002-07-22
SK131498A3 (en)	2000-09-12
CA2249603A1 (en)	1997-10-09
DE69733996D1 (de)	2005-09-22
IL125377A (en)	2005-07-25
US6462048B2 (en)	2002-10-08
CZ293628B6 (cs)	2004-06-16
IS4813A (is)	1998-07-29
ID17781A (id)	1998-01-29
US6924289B2 (en)	2005-08-02
IL125377A0 (en)	1999-03-12
DE69733996T2 (de)	2006-07-20
DZ2198A1 (fr)	2002-12-02
ATE302182T1 (de)	2005-09-15
JP3118467B2 (ja)	2000-12-18
NZ325914A (en)	1999-09-29
KR100305071B1 (ko)	2001-12-12
AU1317097A (en)	1997-10-22
OA10879A (en)	2001-10-05
EP0894085B1 (en)	2005-08-17
HRP970175A2 (en)	1998-12-31
HUP9902160A3 (en)	2001-02-28
UY24498A1 (es)	2000-09-29
CN1214043A (zh)	1999-04-14
WO1997036867A1 (en)	1997-10-09
HUP9902160A2 (hu)	1999-11-29
NO984513D0 (no)	1998-09-28
ZA972690B (en)	1998-09-28
MA26425A1 (fr)	2004-12-20
AP9700955A0 (en)	1997-04-30
AU706839B2 (en)	1999-06-24
EA199800771A1 (ru)	1999-06-24
AR006390A1 (es)	1999-08-25
HK1019446A1 (en)	2000-02-11
KR20000005083A (ko)	2000-01-25
EP0894085A1 (en)	1999-02-03
CZ305298A3 (cs)	1999-07-14
ES2246058T3 (es)	2006-02-01
BG64176B1 (bg)	2004-03-31
US20030027812A1 (en)	2003-02-06
EA001485B1 (ru)	2001-04-23
AP824A (en)	2000-04-28
PL329170A1 (en)	1999-03-15
BG102791A (en)	1999-11-30
MY118498A (en)	2004-11-30
HN1997000023A (es)	1997-06-05
CO4650033A1 (es)	1998-09-03
TNSN97056A1 (fr)	2005-03-15
TW413679B (en)	2000-12-01
YU11997A (sh)	1999-09-27
UA70284C2 (en)	2004-10-15

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DK0847388T3 (da)	2003-08-18	Heterocyklisk substituerede biphenylamidderivater, fremstilling heraf og anvendelse heraf som fungicider
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DK1095025T3 (da)	2003-04-07	Benzimidazoler, deres fremstilling og deres anvendelse som lægemidler
IS6566A (is)	2002-09-24	Indólín-2-ón afleiður, framleiðsla og notkun þeirra sem mjaltavaka (ocytocin) viðtakabindlar
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NO20006460L (no)	2001-02-19	4, 5, 6 og 7-Indol og indolinderivater, deres fremstilling og anvendelse
NO963117D0 (no)	1996-07-25	Indol-derivater som 5-HT1-agonister
NO985307L (no)	1999-01-12	Distamycinderivater, fremgangsmÕte for deres fremstilling, og deres anvende
NO971136D0 (no)	1997-03-12	Aminoalkyl- og acylaminoaklyleter, fremgangsmåte for fremstilling derav og anvendelse som bradykinin-reseptor antagonister
NO20004271D0 (no)	2000-08-25	Benzylpiperazinyl- og benzylpiperidinyl etanonderivater, deres fremstilling og deres anvendelse som dopamin D4 reseptorantagonister
NO20004144D0 (no)	2000-08-18	Heterocykliske forbindelser, deres fremstilling og anvendelse som takykinin reseptor antagonister
NO20001934D0 (no)	2000-04-13	3-Substituerte tetrahydropyridopyrimidinon-derivater, deres fremstilling og anvendelse
NO20001937D0 (no)	2000-04-13	2-substituerte 1,2-benzisotiazol-derivater og deres anvendelse som serotonin-antagonister (5-HT1A, 5-HT1B og 5-HT1D)
NO20002959L (no)	2000-08-09	Echinocandinderivater, fremgangsmÕte for fremstilling av slike og deres anvendelse som anti-soppmidler
AU2883397A (en)	1998-01-05	5-alkoxy-tryptamine derivatives, their preparation and their use as 5-ht1d receptor agonists
NO992436D0 (no)	1999-05-20	N(imidazolylbutyl)benzensulfonamidderivater, deres fremstilling og terapeutiske anvendelse
DK1076651T3 (da)	2005-08-15	Substituerede sulfonylcyanamider, fremgangsmåde til fremstilling heraf og anvendelsen heraf som lægemidler
DK1015449T3 (da)	2005-03-21	(Hetero)arylsulfonamidderivater, deres fremstilling og deres anvendelse som faktor Xa-inhibitorer