MA24471A1 - Composes et methodes pour la preparation d'acides 4-phenyl-4-cyanocyclohexanoiques substitues - Google Patents

Composes et methodes pour la preparation d'acides 4-phenyl-4-cyanocyclohexanoiques substitues

Info

Publication number: MA24471A1
Authority: MA; Morocco
Prior art keywords: phenyl; substituted; compounds; preparation; methods
Prior art date: 1997-02-12

Application number

MA24962A

Other languages

English (en)

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-02-12

Filing date

1998-02-12

Publication date

1998-10-01

1998-02-12 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

1998-10-01 Publication of MA24471A1 publication Critical patent/MA24471A1/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/21—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing rings other than six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pulmonology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Epoxy Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Catalysts (AREA)
Plural Heterocyclic Compounds (AREA)

MA24962A 1997-02-12 1998-02-12 Composes et methodes pour la preparation d'acides 4-phenyl-4-cyanocyclohexanoiques substitues MA24471A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US3760897P	1997-02-12	1997-02-12

Publications (1)

Publication Number	Publication Date
MA24471A1 true MA24471A1 (fr)	1998-10-01

Family

ID=21895265

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA24962A MA24471A1 (fr)	1997-02-12	1998-02-12	Composes et methodes pour la preparation d'acides 4-phenyl-4-cyanocyclohexanoiques substitues

Country Status (37)

Country	Link
US (1)	US6337408B1 (fr)
EP (1)	EP1023279B8 (fr)
JP (4)	JP3786971B2 (fr)
KR (1)	KR100412008B1 (fr)
CN (2)	CN1854131A (fr)
AP (1)	AP1215A (fr)
AR (2)	AR012550A1 (fr)
AT (2)	ATE300517T1 (fr)
AU (1)	AU725484B2 (fr)
BG (1)	BG63541B1 (fr)
BR (1)	BR9808637A (fr)
CA (1)	CA2279951A1 (fr)
CO (1)	CO4950534A1 (fr)
CY (1)	CY2478B1 (fr)
DE (3)	DE69836928T2 (fr)
DK (2)	DK1524268T3 (fr)
DZ (1)	DZ2423A1 (fr)
EA (1)	EA001783B1 (fr)
ES (3)	ES2196551T3 (fr)
HU (1)	HUP0001801A3 (fr)
ID (1)	ID23527A (fr)
IL (7)	IL131270A (fr)
MA (1)	MA24471A1 (fr)
MY (1)	MY118813A (fr)
NO (1)	NO993863L (fr)
NZ (1)	NZ337084A (fr)
OA (1)	OA11144A (fr)
PL (1)	PL193366B1 (fr)
PT (2)	PT1023279E (fr)
SI (2)	SI1295869T1 (fr)
SK (1)	SK108899A3 (fr)
TR (1)	TR199901920T2 (fr)
TW (1)	TW442455B (fr)
UA (1)	UA58533C2 (fr)
UY (2)	UY24882A1 (fr)
WO (1)	WO1998034584A2 (fr)
ZA (1)	ZA981125B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA67753C2 (uk) *	1997-10-10	2004-07-15	Смітклайн Бічам Корпорейшн	Спосіб отримання заміщених 4-феніл-4-ціанциклогексанових кислот
US6452022B1 (en) *	1997-10-10	2002-09-17	Smithkline Beecham Corporation	Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids
UY26268A1 (es) *	1999-08-06	2001-01-31	Smithkline Beecham Corp	Procedimiento para preparar acidos a traves de alfa-cloroep xi- esteres ley 17164 art 127
US20040220424A1 (en) *	1999-08-06	2004-11-04	Smithkline Beecham Corporation	Process for preparing acids via alpha-chloroepoxy esters
GB9920152D0 (en) *	1999-08-25	1999-10-27	Smithkline Beecham Plc	Novel process
US6555572B2 (en)	2000-03-16	2003-04-29	Inflazyme Pharmaceuticals Ltd.	Benzylated PDE4 inhibitors
CN102491959B (zh) *	2011-12-19	2015-03-25	江苏澄扬作物科技有限公司	一种环氧乙烷衍生物的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8320943D0 (en) *	1983-08-03	1983-09-07	Lilly Industries Ltd	Organic compounds
MX9301903A (es) *	1992-04-02	1994-08-31	Smithkline Beecham Corp	Compuestos.
HU225869B1 (en) *	1992-04-02	2007-11-28	Smithkline Beecham Corp	Compounds with antiallergic and antiinflammatory activity and pharmaceutical compns. contg. them

1998
- 1998-02-10 AR ARP980100587A patent/AR012550A1/es unknown
- 1998-02-10 MY MYPI98000536A patent/MY118813A/en unknown
- 1998-02-10 UY UY24882A patent/UY24882A1/es not_active IP Right Cessation
- 1998-02-11 ZA ZA981125A patent/ZA981125B/xx unknown
- 1998-02-12 EP EP98908534A patent/EP1023279B8/fr not_active Expired - Lifetime
- 1998-02-12 ES ES98908534T patent/ES2196551T3/es not_active Expired - Lifetime
- 1998-02-12 AU AU66544/98A patent/AU725484B2/en not_active Ceased
- 1998-02-12 BR BR9808637-5A patent/BR9808637A/pt not_active Application Discontinuation
- 1998-02-12 DZ DZ980033A patent/DZ2423A1/fr active
- 1998-02-12 PT PT98908534T patent/PT1023279E/pt unknown
- 1998-02-12 DK DK04078092T patent/DK1524268T3/da active
- 1998-02-12 JP JP53506598A patent/JP3786971B2/ja not_active Expired - Fee Related
- 1998-02-12 DE DE69836928T patent/DE69836928T2/de not_active Expired - Lifetime
- 1998-02-12 SI SI9830794T patent/SI1295869T1/sl unknown
- 1998-02-12 ID IDW990806A patent/ID23527A/id unknown
- 1998-02-12 WO PCT/US1998/002749 patent/WO1998034584A2/fr not_active Ceased
- 1998-02-12 DE DE69813596T patent/DE69813596T2/de not_active Expired - Lifetime
- 1998-02-12 AT AT02078056T patent/ATE300517T1/de not_active IP Right Cessation
- 1998-02-12 CA CA002279951A patent/CA2279951A1/fr not_active Abandoned
- 1998-02-12 CN CNA2006100819583A patent/CN1854131A/zh active Pending
- 1998-02-12 KR KR10-1999-7007192A patent/KR100412008B1/ko not_active Expired - Fee Related
- 1998-02-12 ES ES04078092T patent/ES2280008T3/es not_active Expired - Lifetime
- 1998-02-12 CO CO98007356A patent/CO4950534A1/es unknown
- 1998-02-12 DK DK98908534T patent/DK1023279T3/da active
- 1998-02-12 PL PL335031A patent/PL193366B1/pl not_active IP Right Cessation
- 1998-02-12 NZ NZ337084A patent/NZ337084A/en unknown
- 1998-02-12 DE DE69831022T patent/DE69831022T2/de not_active Expired - Lifetime
- 1998-02-12 MA MA24962A patent/MA24471A1/fr unknown
- 1998-02-12 SI SI9830872T patent/SI1524268T1/sl unknown
- 1998-02-12 PT PT04078092T patent/PT1524268E/pt unknown
- 1998-02-12 SK SK1088-99A patent/SK108899A3/sk unknown
- 1998-02-12 TR TR1999/01920T patent/TR199901920T2/xx unknown
- 1998-02-12 AP APAP/P/1999/001618A patent/AP1215A/en active
- 1998-02-12 IL IL13127098A patent/IL131270A/xx not_active IP Right Cessation
- 1998-02-12 ES ES02078056T patent/ES2246373T3/es not_active Expired - Lifetime
- 1998-02-12 CN CNB988023776A patent/CN1301982C/zh not_active Expired - Fee Related
- 1998-02-12 EA EA199900735A patent/EA001783B1/ru not_active IP Right Cessation
- 1998-02-12 HU HU0001801A patent/HUP0001801A3/hu unknown
- 1998-02-12 AT AT98908534T patent/ATE237603T1/de not_active IP Right Cessation
- 1998-07-20 TW TW087101889A patent/TW442455B/zh active
- 1998-08-06 UY UY25127A patent/UY25127A1/es not_active IP Right Cessation
- 1998-12-02 UA UA99084524A patent/UA58533C2/uk unknown
1999
- 1999-08-10 BG BG103651A patent/BG63541B1/bg unknown
- 1999-08-11 NO NO993863A patent/NO993863L/no unknown
- 1999-08-12 OA OA9900176A patent/OA11144A/en unknown
2000
- 2000-03-22 US US09/533,368 patent/US6337408B1/en not_active Expired - Fee Related
2002
- 2002-07-29 IL IL150955A patent/IL150955A/en not_active IP Right Cessation
2004
- 2004-01-05 JP JP2004000418A patent/JP4093967B2/ja not_active Expired - Fee Related
- 2004-06-09 JP JP2004171348A patent/JP4053024B2/ja not_active Expired - Fee Related
- 2004-06-09 JP JP2004171346A patent/JP4053023B2/ja not_active Expired - Fee Related
- 2004-09-08 CY CY0400070A patent/CY2478B1/xx unknown
2005
- 2005-01-06 IL IL16618505A patent/IL166185A0/xx unknown
- 2005-01-06 IL IL16618405A patent/IL166184A0/xx unknown
- 2005-01-06 IL IL16618705A patent/IL166187A0/xx unknown
- 2005-01-06 IL IL16618805A patent/IL166188A0/xx unknown
- 2005-01-06 IL IL16618605A patent/IL166186A0/xx unknown
2006
- 2006-04-05 AR ARP060101344A patent/AR050308A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
HUP0001801A3 (en)	2001-12-28
UY25127A1 (es)	1998-11-27
IL150955A (en)	2006-07-05
IL166188A0 (en)	2006-01-15
NO993863D0 (no)	1999-08-11
DE69836928D1 (de)	2007-03-08
DK1524268T3 (da)	2007-05-14
AP1215A (en)	2003-10-14
NO993863L (no)	1999-08-11
WO1998034584A3 (fr)	1998-11-19
IL166184A0 (en)	2006-01-15
US6337408B1 (en)	2002-01-08
MY118813A (en)	2005-01-31
JP2004292460A (ja)	2004-10-21
TR199901920T2 (xx)	1999-11-22
ATE300517T1 (de)	2005-08-15
PT1023279E (pt)	2003-08-29
UA58533C2 (uk)	2003-08-15
AR050308A2 (es)	2006-10-18
SI1524268T1 (sl)	2007-04-30
IL166185A0 (en)	2006-01-15
IL131270A0 (en)	2001-01-28
SI1295869T1 (sl)	2005-12-31
NZ337084A (en)	2001-04-27
ATE237603T1 (de)	2003-05-15
DE69831022D1 (de)	2005-09-01
JP3786971B2 (ja)	2006-06-21
AR012550A1 (es)	2000-11-08
KR20000070927A (ko)	2000-11-25
ES2196551T3 (es)	2003-12-16
AU6654498A (en)	1998-08-26
IL166187A0 (en)	2006-01-15
CO4950534A1 (es)	2000-09-01
DZ2423A1 (fr)	2003-01-04
EP1023279B8 (fr)	2003-08-13
ZA981125B (en)	1998-08-21
SK108899A3 (en)	2000-01-18
IL166186A0 (en)	2006-01-15
ID23527A (id)	2000-04-27
PT1524268E (pt)	2007-03-30
CA2279951A1 (fr)	1998-08-13
ES2246373T3 (es)	2006-02-16
CN1246855A (zh)	2000-03-08
PL193366B1 (pl)	2007-02-28
AU725484B2 (en)	2000-10-12
DK1023279T3 (da)	2003-07-21
EP1023279A4 (fr)	2000-10-04
EP1023279A2 (fr)	2000-08-02
JP4053023B2 (ja)	2008-02-27
HUP0001801A2 (hu)	2000-10-28
OA11144A (en)	2003-04-17
BG63541B1 (bg)	2002-04-30
JP2001510482A (ja)	2001-07-31
UY24882A1 (es)	2001-08-27
IL131270A (en)	2005-05-17
EA199900735A1 (ru)	2000-02-28
JP2004149546A (ja)	2004-05-27
AP9901618A0 (en)	1999-09-30
DE69831022T2 (de)	2006-04-20
BG103651A (en)	2000-02-29
PL335031A1 (en)	2000-03-27
DE69836928T2 (de)	2007-11-08
JP4053024B2 (ja)	2008-02-27
CN1301982C (zh)	2007-02-28
JP2004269546A (ja)	2004-09-30
WO1998034584A2 (fr)	1998-08-13
EA001783B1 (ru)	2001-08-27
BR9808637A (pt)	2000-07-04
ES2280008T3 (es)	2007-09-01
CN1854131A (zh)	2006-11-01
CY2478B1 (en)	2005-06-03
KR100412008B1 (ko)	2003-12-24
EP1023279B1 (fr)	2003-04-16
DE69813596T2 (de)	2004-02-12
DE69813596D1 (de)	2003-05-22
HK1037613A1 (en)	2002-02-15
TW442455B (en)	2001-06-23
JP4093967B2 (ja)	2008-06-04

Publication	Publication Date	Title
FI894335L (fi)	1990-03-15	Jatkuva ultraäänimenetelmä proteiinikapseloitujen mikrokuplien valmistamiseksi
EP0601058A4 (fr)	1995-05-31	Formulations transdermiques pour l'administration de prazosine.
BR9608270A (pt)	1999-05-04	Composição compreendendo amoxicilina e acido clavulánico
FI894924A7 (fi)	1990-04-19	Menetelmä 5-substituoitujen 3-furaldehydien valmistamiseksi
EE04681B1 (et)	2006-08-15	3,6-poolketaalid 9a-asaliidide klassist, nende valmistamismeetod ja farmatseutiline kompositsioon
ITMI951538A0 (it)	1995-07-14	Procedimento ed impianto per la disidratazione di foraggio particolarmente per la disidratazione dell'erba medica
EP0789579A4 (fr)	1998-04-29	Composes d'azacyclohexapeptide
IT1272924B (it)	1997-07-01	Procedimento per la preparazione di composti ciclopentadienilici e composti cosi' ottenibili
TR199701051A3 (tr)	1999-03-22	2' -Fluoro-5-metil- -l-arabino-furanosilüridin hazirlanma prosesi
DZ2641A1 (fr)	2003-03-15	Nouveaux procédés pour la préparation d'oméprazole.
MA24471A1 (fr)	1998-10-01	Composes et methodes pour la preparation d'acides 4-phenyl-4-cyanocyclohexanoiques substitues
FI971311L (fi)	1997-03-27	Menetelmiä syklopropaanikarboksyylihapon ja sen johdosten valmistamiseksi
DZ2619A1 (fr)	2003-03-08	Procédé pour la préparation d'acides 4-phényl-4-cyanocyclohexanoïques substitués.
FR2692488B1 (fr)	1995-01-27	Structure pour la pratique de l'escalade.
MA24831A1 (fr)	1999-12-31	Procede pour la preparation d'acides hydroxamiques
FI964410A7 (fi)	1996-11-01	Menetelmä 4-amino-delta4-3-ketosteroidien valmistamiseksi 4-nitro-delt a4-3-ketosteroidien kautta
EP0761687A4 (fr)	2000-04-19	Procede de preparation d'un anticorps
EP0862738A4 (fr)	2000-10-18	Mesure de la teneur en or d'un alliage coule
EE9500004A (et)	1995-12-15	Meetod bensaldehüüdi valmistamiseks
ITMI931371A1 (it)	1994-12-25	Procedimento per la preparazione dell'erdosteina
FI901316A7 (fi)	1990-10-01	Menetelmä 4(5)-imidatsolien valmistamiseksi
NO994793L (no)	1999-10-01	Fremgangsmåte for fremstilling av clavulansyre
FI955110A7 (fi)	1996-04-27	Menetelmä massan sakeuden lisäämiseksi
FI956236A7 (fi)	1995-12-22	Uusi menetelmä 17 beta-substituoitujen 4-atsa-androstaanijohdannaisten valmistamiseksi
FI951285A7 (fi)	1996-09-22	Pilokarpiinin valmistusmenetelmä