ZA90511B - Derivatives of benzocycloalkenyldihydroxyalkanoic acid,process or preparation and medications containing them - Google Patents

Derivatives of benzocycloalkenyldihydroxyalkanoic acid,process or preparation and medications containing them

Info

Publication number: ZA90511B
Authority: ZA; South Africa
Prior art keywords: benzocycloalkenyldihydroxyalkanoic; derivatives; preparation; acid; medications containing
Prior art date: 1989-01-24

Application number

ZA90511A

Other languages

English (en)

Inventor

Didier Festal

Festal Didier

Jean-Yves Nioche

Nioche Jean-Yves

Denis Descours

Descours Denis

Robert Bellemin

Bellemin Robert

Jacques Decerprit

Decerprit Jacques

Original Assignee

Lipha

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-01-24

Filing date

1990-01-24

Publication date

1990-10-31

1990-01-24 Application filed by Lipha filed Critical Lipha

1990-10-31 Publication of ZA90511B publication Critical patent/ZA90511B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/235—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings
- C07C47/238—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings having unsaturation outside the aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/24—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
- C07C49/665—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system
- C07C49/67—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system having two rings, e.g. tetralones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Pyrane Compounds (AREA)

ZA90511A 1989-01-24 1990-01-24 Derivatives of benzocycloalkenyldihydroxyalkanoic acid,process or preparation and medications containing them ZA90511B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8900790A FR2642065B1 (fr)	1989-01-24	1989-01-24	Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant

Publications (1)

Publication Number	Publication Date
ZA90511B true ZA90511B (en)	1990-10-31

Family

ID=9378002

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA90511A ZA90511B (en)	1989-01-24	1990-01-24	Derivatives of benzocycloalkenyldihydroxyalkanoic acid,process or preparation and medications containing them

Country Status (28)

Country	Link
US (1)	US5082859A (es)
EP (1)	EP0380392B1 (es)
JP (1)	JP2561354B2 (es)
AR (1)	AR247206A1 (es)
AT (1)	ATE104666T1 (es)
AU (1)	AU629602B2 (es)
CA (1)	CA2008341C (es)
CZ (1)	CZ278567B6 (es)
DD (2)	DD291749A5 (es)
DE (1)	DE69008205T2 (es)
DK (1)	DK0380392T3 (es)
DZ (1)	DZ1390A1 (es)
ES (1)	ES2055350T3 (es)
FR (1)	FR2642065B1 (es)
GE (1)	GEP19971017B (es)
HU (1)	HU206307B (es)
IE (1)	IE64243B1 (es)
IL (1)	IL93124A (es)
MA (1)	MA21737A1 (es)
NO (1)	NO173992C (es)
NZ (1)	NZ232226A (es)
OA (1)	OA09190A (es)
PT (1)	PT92945B (es)
RU (1)	RU2012554C1 (es)
SK (1)	SK34190A3 (es)
TN (1)	TNSN90008A1 (es)
YU (1)	YU48227B (es)
ZA (1)	ZA90511B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2630110B1 (fr) *	1988-04-13	1990-07-27	Adir	Nouveaux derives heteroarotinoides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2630111B1 (fr) *	1988-04-13	1990-07-27	Adir	Nouveaux derives trieniques de structure chromenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU4540693A (en) *	1992-06-25	1994-01-24	G.D. Searle & Co.	Phenyl amidine alkanoic acids and lactones useful as platelet aggregation inhibitors
US6083497A (en)	1997-11-05	2000-07-04	Geltex Pharmaceuticals, Inc.	Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
KR100668575B1 (ko) *	1997-12-19	2007-01-17	워너-램버트 익스포트 리미티드	1,3-디올의 합성방법
FR2772761B1 (fr)	1997-12-23	2000-05-26	Lipha	Nouveaux derives de n-phenylamide et n-pyridylamide, leur procede de preparation et compositions pharmaceutiques les contenant
US20050043272A1 (en) *	2003-07-11	2005-02-24	Pro-Pharmaceuticals, Inc.	Compositions and methods for hydrophobic drug delivery
US20050053664A1 (en) *	2003-09-08	2005-03-10	Eliezer Zomer	Co-administration of a polysaccharide with a chemotherapeutic agent for the treatment of cancer
EP1718146A2 (en) *	2004-02-13	2006-11-08	Pro-Pharmaceuticals, Inc.	Compositions and methods used to treat acne and candida
US20080286251A1 (en) *	2004-08-02	2008-11-20	Propharmaceuticals, Inc.	Compositions and Methods for the Enhancement of Chemotherapy with Microbial Cytotoxins
JP2008524159A (ja) *	2004-12-15	2008-07-10	ゾルファイファーマスーティカルズゲゼルシャフトミットベシュレンクテルハフツング	ＮＥＰ阻害剤、内因性エンドセリン産生系の阻害剤およびＨＭＧＣｏＡレダクターゼ阻害剤を含有する医薬組成物
US7776889B2 (en) *	2005-03-31	2010-08-17	Schering Corporation	Spirocyclic thrombin receptor antagonists
EP1919393A2 (en) *	2005-09-01	2008-05-14	Prescient Medical, Inc.	Drugs coated on a device to treat vulnerable plaque
BRPI0713768A2 (pt)	2006-07-05	2012-10-30	Nycomed Gmbh	combinação de inibidores de reductase de hmg-coa com inibidores de fosfodiesterase 4 para o tratamento de doenças pulmonares inflamatórias
CN101570510B (zh) *	2008-04-30	2011-08-31	上海医药工业研究院	喹啉类化合物及其药物组合物、制备方法和应用
AU2013214693B2 (en)	2012-02-02	2017-02-23	Kenneth Gek-Jin OOI	Improvements in tear film stability
MY160723A (en) *	2013-12-30	2017-03-15	Univ Putra Malaysia	An anticoagulant
MX2019009213A (es)	2017-01-23	2019-09-27	Dong Wha Pharm Co Ltd	Formulación compleja que comprende inhibidor de la hmg-coa reductasa y clopidogrel.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3063585D1 (en) *	1979-05-19	1983-07-07	Beecham Group Plc	Chroman derivatives, processes for their preparation and pharmaceutical compositions containing them
US4556676A (en)	1979-11-01	1985-12-03	Pfizer Inc.	Antidepressant derivatives of trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
HU198005B (en) *	1984-12-04	1989-07-28	Sandoz Ag	Process for producing mevqlolakton, derivatives, its indene-analogues and pharmaceutical compositions containing them
JPH0681745B2 (ja) *	1986-01-16	1994-10-19	シェリング・コ−ポレ−ション	縮合ベンゾアゼピン
JPS62181276A (ja) *	1986-02-06	1987-08-08	Sagami Chem Res Center	２ｈ−クロメン誘導体
GB8611837D0 (en) *	1986-05-15	1986-06-25	Plessey Co Plc	Photochromic spiropyran compounds
EP0298466A3 (en) *	1987-07-10	1990-10-24	F. Hoffmann-La Roche Ag	Substituted alkene carboxylic acid amides and derivatives

1989
- 1989-01-24 FR FR8900790A patent/FR2642065B1/fr not_active Expired - Lifetime
1990
- 1990-01-22 DE DE69008205T patent/DE69008205T2/de not_active Expired - Fee Related
- 1990-01-22 ES ES90400161T patent/ES2055350T3/es not_active Expired - Lifetime
- 1990-01-22 EP EP90400161A patent/EP0380392B1/fr not_active Expired - Lifetime
- 1990-01-22 DK DK90400161.7T patent/DK0380392T3/da active
- 1990-01-22 DZ DZ900008A patent/DZ1390A1/fr active
- 1990-01-22 IL IL9312490A patent/IL93124A/en not_active IP Right Cessation
- 1990-01-22 AT AT9090400161T patent/ATE104666T1/de not_active IP Right Cessation
- 1990-01-23 DD DD90337274A patent/DD291749A5/de not_active IP Right Cessation
- 1990-01-23 IE IE26090A patent/IE64243B1/en not_active IP Right Cessation
- 1990-01-23 HU HU90239A patent/HU206307B/hu not_active IP Right Cessation
- 1990-01-23 MA MA21999A patent/MA21737A1/fr unknown
- 1990-01-23 DD DD344416A patent/DD300422A5/de unknown
- 1990-01-23 AR AR90315991A patent/AR247206A1/es active
- 1990-01-23 OA OA59728A patent/OA09190A/xx unknown
- 1990-01-23 CA CA002008341A patent/CA2008341C/fr not_active Expired - Fee Related
- 1990-01-23 NO NO900309A patent/NO173992C/no unknown
- 1990-01-23 RU SU904743212A patent/RU2012554C1/ru active
- 1990-01-24 US US07/469,121 patent/US5082859A/en not_active Expired - Fee Related
- 1990-01-24 JP JP2012746A patent/JP2561354B2/ja not_active Expired - Lifetime
- 1990-01-24 PT PT92945A patent/PT92945B/pt not_active IP Right Cessation
- 1990-01-24 TN TNTNSN90008A patent/TNSN90008A1/fr unknown
- 1990-01-24 NZ NZ232226A patent/NZ232226A/xx unknown
- 1990-01-24 CZ CS90341A patent/CZ278567B6/cs not_active IP Right Cessation
- 1990-01-24 SK SK341-90A patent/SK34190A3/sk unknown
- 1990-01-24 YU YU12490A patent/YU48227B/sh unknown
- 1990-01-24 ZA ZA90511A patent/ZA90511B/xx unknown
- 1990-01-24 AU AU48797/90A patent/AU629602B2/en not_active Ceased
1993
- 1993-03-30 GE GEAP1993645A patent/GEP19971017B/en unknown

Also Published As

Publication number	Publication date
NZ232226A (en)	1991-09-25
JPH02258738A (ja)	1990-10-19
DK0380392T3 (da)	1994-08-29
IL93124A0 (en)	1990-11-05
RU2012554C1 (ru)	1994-05-15
AU647642B2 (en)	1994-03-24
SK278578B6 (en)	1997-10-08
ATE104666T1 (de)	1994-05-15
DE69008205D1 (de)	1994-05-26
DE69008205T2 (de)	1994-10-06
MA21737A1 (fr)	1990-10-01
OA09190A (fr)	1992-06-30
PT92945B (pt)	1995-12-29
EP0380392A2 (fr)	1990-08-01
AU4879790A (en)	1990-09-13
NO173992C (no)	1994-03-02
YU48227B (sh)	1997-08-22
TNSN90008A1 (fr)	1991-03-05
CA2008341C (fr)	1997-03-18
IL93124A (en)	1995-01-24
FR2642065B1 (fr)	1991-05-24
IE64243B1 (en)	1995-07-26
NO900309L (no)	1990-07-25
EP0380392A3 (en)	1990-09-12
CZ278567B6 (en)	1994-03-16
AR247206A1 (es)	1994-11-30
PT92945A (pt)	1990-07-31
SK34190A3 (en)	1997-10-08
EP0380392B1 (fr)	1994-04-20
GEP19971017B (en)	1997-06-18
DD291749A5 (de)	1991-07-11
HUT53059A (en)	1990-09-28
CZ34190A3 (en)	1993-08-11
AU629602B2 (en)	1992-10-08
DD300422A5 (de)	1992-06-11
FR2642065A1 (fr)	1990-07-27
HU206307B (en)	1992-10-28
YU12490A (en)	1991-10-31
ES2055350T3 (es)	1994-08-16
NO173992B (no)	1993-11-22
DZ1390A1 (fr)	2004-09-13
IE900260L (en)	1990-07-24
JP2561354B2 (ja)	1996-12-04
US5082859A (en)	1992-01-21
CA2008341A1 (fr)	1990-07-24
HU900239D0 (en)	1990-03-28
NO900309D0 (no)	1990-01-23
AU2061392A (en)	1992-10-15

Publication	Publication Date	Title
HU199453B (en)	1990-02-28	Process for producing quinoloncarboxylic acid derivatives and pharmaceutical compositions comprising same
HUT64746A (en)	1994-02-28	Process for the production of 1-cycloalkyl-piperidines and medical preparations containing them
HUT51272A (en)	1990-04-28	Process for producing thiadiazin derivatives and pharmaceutical composirions containing them
IL93954A0 (en)	1990-12-23	5-alkylquinolonecarboxylic acids,their preparation and medicaments containing them
ZA90511B (en)	1990-10-31	Derivatives of benzocycloalkenyldihydroxyalkanoic acid,process or preparation and medications containing them
HUT46907A (en)	1988-12-28	Process for production of derivatives of 1,4-dihydropiridine and medical preparatives containing such substances
ZA885781B (en)	1990-04-25	Alkylaminoalkoxyphenyl derivatives,process of preparation and compositions containing the same
HUT43820A (en)	1987-12-28	Process for producing n-(-2-((-2-hydroxy-phenyl-)(-phenyl-)-methylene-aminosquare )-ethyl-)-acetamide derivatives and pharmaceutical compositions containing them
IL83049A (en)	1991-12-12	4-quinolinone-3-carboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them
PT85337A (en)	1987-08-01	Process for the preparation of cycloalkyl-substituted 4-pyridil derivatives and of pharmaceutical compositions containing the same
CS382891A3 (en)	1992-04-15	N-arylpiperizinealkaneamide derivatives, process of their preparation and pharmaceuticals based thereon
HUT46030A (en)	1988-09-28	Process for producing citostatic antracyclin-glycoside derivatives and pharmaceutical compositions containing them
HU895952D0 (en)	1990-02-28	Process for the preparation of substituted pyrrolidone-2-carboxylic acid derivatives and pharmaceutical compositions containing them
CS382191A3 (en)	1992-05-13	Benzoxazol- and benzothiazolamine derivatives, process of their preparation and pharmaceuticals based thereon
GR3001052T3 (en)	1992-03-20	Novel 16,17-acetalsubstituted pregnane-21-oic acid derivatives, process for the preparation thereof and pharmaceutical preparation containing them
IL81978A (en)	1991-03-10	Indenopyrimidine derivatives,process for their preparation and pharmaceutical compositions containing them
PT83231A (en)	1986-09-01	Process for the preparation of gem-dihalo-1,8-diamino-4-aza-octanes and of pharmaceutical compositions containing the same
HUT49615A (en)	1989-10-30	Process for producing cefemkarboxylic acid derivatives and pharmaceutical compositions comprising same
IL89836A0 (en)	1989-12-15	Penicilanic acid derivatives,process for their preparation and pharmaceutical compositions containing them
HU904211D0 (en)	1990-12-28	Process for the production of medical preparations containing 10-amino-5,6-dihydro-11h-dibenzo/b,e/azepin-6,11-dion and its derivatives
HUT47521A (en)	1989-03-28	Process for producing phenoxy-alkyl-carboxylic acid derivatives and pharmaceuticals comprising same
IL92139A0 (en)	1990-07-12	Penicillanic acid derivatives,their manufacture and pharmaceutical compositions containing them
HUT46020A (en)	1988-09-28	Process for producing cepheme-carboxylic acid derivatives and pharmaceutical compositions containing them
HUT45539A (en)	1988-07-28	Process for producing cepheme-carboxylic acid derivatives and pharmaceutical compositions containing them
PT84406A (en)	1987-04-01	Process for the preparation of aromatic omega-alkylimino-tetrahydro-6h-1,3-thiazin-6-one derivatives and of pharmaceutical compositions containing the same