AR247206A1 - Un procedimiento de preparacion de derivados de acidos benzocicloalquenil-dihidroxi-alcanoico. - Google Patents
Un procedimiento de preparacion de derivados de acidos benzocicloalquenil-dihidroxi-alcanoico.Info
- Publication number
- AR247206A1 AR247206A1 AR90315991A AR31599190A AR247206A1 AR 247206 A1 AR247206 A1 AR 247206A1 AR 90315991 A AR90315991 A AR 90315991A AR 31599190 A AR31599190 A AR 31599190A AR 247206 A1 AR247206 A1 AR 247206A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- chlorine
- phenyl
- substituted
- positions
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 4
- 150000007513 acids Chemical class 0.000 title abstract 2
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 5
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 4
- 239000000460 chlorine Substances 0.000 abstract 4
- 229910052801 chlorine Inorganic materials 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical compound BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 241000670727 Amida Species 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/235—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings
- C07C47/238—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/24—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
- C07C49/665—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system
- C07C49/67—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system having two rings, e.g. tetralones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyrane Compounds (AREA)
Abstract
PREPARACION DE DERIVADOS DE ACIDOS BENZOCICLOALQUENIL-DIHIDROXI-ALCANOICO DE FORMULA (1), EN LA CUAL, X ES -CH2-, OXIGENO O DE AZUFRE; R1 Y R2 SON HIDROGENO O ALQUILO; R1 Y R2 PUEDEN TAMBIEN FORMAR EN CONJUNTO UNA CADENA ALQUILENO -(CH2)N-, CON N=4 O 5 Y SUSTITUIDA O NO POR UNO O DOS ALQUILO; R3 Y R4 QUE PUEDEN SER HIDROGENO, FLUOR, CLORO O BROMO, CF3, N,N- DIALQUILAMINO, ALQUILO, ALCOXI, FENILO SUSTITUIDO O NO POR UN MAXIMO DE DOS, ALQUILO, FLUOR O CLORO, QUEDANDO ENTENDIDO QUE CUANDO UNO DE LOS R3 O R4 ES CF3, N,N-DIALQUILAMINO, FENILO O FENILO SUSTITUIDO, SE ENCUENTRA EN LAS POSICIONES 3', 4' O 5' Y EL OTRO ES H; R5 Y R6 SON ATOMOS DE HIDROGENO, FLUOR, CLORO O BROMO, CF3, ALQUILO, ALCOXI O FENILO SUSTITUIDO O NO POR UN MAXIMO DE DOS ALQUILO, ALCOXI O FLUOR O CLORO, ACONDICION DE QUE CUANDO UNO DE R5 Y R6 ES CF3, FENILO O FENILO SUSTITUIDO SE ENCUENTRA EN LAS POSICIONES 6 O 7 Y ES H; LOS R3 Y R4 RESPECTIVAMENTE R5 Y R6 PUEDEN TAMBIEN FORMAR EN CONJUNTO, A CONDICION DE ESTAR EN DO S POSICIONES CONTIGUAS, LOS RADICALES DE FORMULAS: -CH=CH-CH=CH-, -(CH2)M- O -O(CH2)PO-, EN LAS CUALES M PUEDE SER IGUAL A 3 O 4 Y P A 1 O 2, QUEDANDO ENTENDIDO QUE CUANDO R3 Y R4,RESPECTIVAMENTE R5 Y R6 SON -O(CH2)NO-,ESTE SE HALLA CONECTADO A LAS POSICIONES 3' Y 4' O 4' Y 5'RESPECTIVAMENTE 6 Y 7; LOS SUSTITUYENTE R7 Y R8 SON H O FORMAN EN CONJUNTO UN DOBLE ENLACE DE GEOMETRIA TRANS (E); LOS SUSTITUYENTES R9 Y R10 SON H O FORMAN EN CONJUNTO UN RESTO DIALQUILMETILENO DE 1 A 3 ATOMOS DE CARBONO, SIENDO R11 CON EL GRUPO CO UNA FUNCION ACIDO LIBRE, ESTER, AMIDA, SAL DE ACIDO O FORMANDO CON R9 UN CICLO DELTA-LACTONA, QUE COMPRENDE POR LO MENOS, A) LA REDUCCION DE UN CETOESTER DE FORMULA (4).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8900790A FR2642065B1 (fr) | 1989-01-24 | 1989-01-24 | Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR247206A1 true AR247206A1 (es) | 1994-11-30 |
Family
ID=9378002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR90315991A AR247206A1 (es) | 1989-01-24 | 1990-01-23 | Un procedimiento de preparacion de derivados de acidos benzocicloalquenil-dihidroxi-alcanoico. |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US5082859A (es) |
| EP (1) | EP0380392B1 (es) |
| JP (1) | JP2561354B2 (es) |
| AR (1) | AR247206A1 (es) |
| AT (1) | ATE104666T1 (es) |
| AU (1) | AU629602B2 (es) |
| CA (1) | CA2008341C (es) |
| CZ (1) | CZ278567B6 (es) |
| DD (2) | DD291749A5 (es) |
| DE (1) | DE69008205T2 (es) |
| DK (1) | DK0380392T3 (es) |
| DZ (1) | DZ1390A1 (es) |
| ES (1) | ES2055350T3 (es) |
| FR (1) | FR2642065B1 (es) |
| GE (1) | GEP19971017B (es) |
| HU (1) | HU206307B (es) |
| IE (1) | IE64243B1 (es) |
| IL (1) | IL93124A (es) |
| MA (1) | MA21737A1 (es) |
| NO (1) | NO173992C (es) |
| NZ (1) | NZ232226A (es) |
| OA (1) | OA09190A (es) |
| PT (1) | PT92945B (es) |
| RU (1) | RU2012554C1 (es) |
| SK (1) | SK34190A3 (es) |
| TN (1) | TNSN90008A1 (es) |
| YU (1) | YU48227B (es) |
| ZA (1) | ZA90511B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2630110B1 (fr) * | 1988-04-13 | 1990-07-27 | Adir | Nouveaux derives heteroarotinoides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2630111B1 (fr) * | 1988-04-13 | 1990-07-27 | Adir | Nouveaux derives trieniques de structure chromenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| AU4540693A (en) * | 1992-06-25 | 1994-01-24 | G.D. Searle & Co. | Phenyl amidine alkanoic acids and lactones useful as platelet aggregation inhibitors |
| US6083497A (en) | 1997-11-05 | 2000-07-04 | Geltex Pharmaceuticals, Inc. | Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers |
| KR100668575B1 (ko) * | 1997-12-19 | 2007-01-17 | 워너-램버트 익스포트 리미티드 | 1,3-디올의 합성방법 |
| FR2772761B1 (fr) | 1997-12-23 | 2000-05-26 | Lipha | Nouveaux derives de n-phenylamide et n-pyridylamide, leur procede de preparation et compositions pharmaceutiques les contenant |
| US20050043272A1 (en) * | 2003-07-11 | 2005-02-24 | Pro-Pharmaceuticals, Inc. | Compositions and methods for hydrophobic drug delivery |
| US20050053664A1 (en) * | 2003-09-08 | 2005-03-10 | Eliezer Zomer | Co-administration of a polysaccharide with a chemotherapeutic agent for the treatment of cancer |
| EP1718146A2 (en) * | 2004-02-13 | 2006-11-08 | Pro-Pharmaceuticals, Inc. | Compositions and methods used to treat acne and candida |
| US20080286251A1 (en) * | 2004-08-02 | 2008-11-20 | Propharmaceuticals, Inc. | Compositions and Methods for the Enhancement of Chemotherapy with Microbial Cytotoxins |
| JP2008524159A (ja) * | 2004-12-15 | 2008-07-10 | ゾルファイ ファーマスーティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | ＮＥＰ阻害剤、内因性エンドセリン産生系の阻害剤およびＨＭＧＣｏＡレダクターゼ阻害剤を含有する医薬組成物 |
| US7776889B2 (en) * | 2005-03-31 | 2010-08-17 | Schering Corporation | Spirocyclic thrombin receptor antagonists |
| EP1919393A2 (en) * | 2005-09-01 | 2008-05-14 | Prescient Medical, Inc. | Drugs coated on a device to treat vulnerable plaque |
| BRPI0713768A2 (pt) | 2006-07-05 | 2012-10-30 | Nycomed Gmbh | combinação de inibidores de reductase de hmg-coa com inibidores de fosfodiesterase 4 para o tratamento de doenças pulmonares inflamatórias |
| CN101570510B (zh) * | 2008-04-30 | 2011-08-31 | 上海医药工业研究院 | 喹啉类化合物及其药物组合物、制备方法和应用 |
| AU2013214693B2 (en) | 2012-02-02 | 2017-02-23 | Kenneth Gek-Jin OOI | Improvements in tear film stability |
| MY160723A (en) * | 2013-12-30 | 2017-03-15 | Univ Putra Malaysia | An anticoagulant |
| MX2019009213A (es) | 2017-01-23 | 2019-09-27 | Dong Wha Pharm Co Ltd | Formulación compleja que comprende inhibidor de la hmg-coa reductasa y clopidogrel. |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3063585D1 (en) * | 1979-05-19 | 1983-07-07 | Beecham Group Plc | Chroman derivatives, processes for their preparation and pharmaceutical compositions containing them |
| US4556676A (en) | 1979-11-01 | 1985-12-03 | Pfizer Inc. | Antidepressant derivatives of trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
| HU198005B (en) * | 1984-12-04 | 1989-07-28 | Sandoz Ag | Process for producing mevqlolakton, derivatives, its indene-analogues and pharmaceutical compositions containing them |
| JPH0681745B2 (ja) * | 1986-01-16 | 1994-10-19 | シェリング・コ−ポレ−ション | 縮合ベンゾアゼピン |
| JPS62181276A (ja) * | 1986-02-06 | 1987-08-08 | Sagami Chem Res Center | ２ｈ−クロメン誘導体 |
| GB8611837D0 (en) * | 1986-05-15 | 1986-06-25 | Plessey Co Plc | Photochromic spiropyran compounds |
| EP0298466A3 (en) * | 1987-07-10 | 1990-10-24 | F. Hoffmann-La Roche Ag | Substituted alkene carboxylic acid amides and derivatives |
-
1989
- 1989-01-24 FR FR8900790A patent/FR2642065B1/fr not_active Expired - Lifetime
-
1990
- 1990-01-22 DE DE69008205T patent/DE69008205T2/de not_active Expired - Fee Related
- 1990-01-22 ES ES90400161T patent/ES2055350T3/es not_active Expired - Lifetime
- 1990-01-22 EP EP90400161A patent/EP0380392B1/fr not_active Expired - Lifetime
- 1990-01-22 DK DK90400161.7T patent/DK0380392T3/da active
- 1990-01-22 DZ DZ900008A patent/DZ1390A1/fr active
- 1990-01-22 IL IL9312490A patent/IL93124A/en not_active IP Right Cessation
- 1990-01-22 AT AT9090400161T patent/ATE104666T1/de not_active IP Right Cessation
- 1990-01-23 DD DD90337274A patent/DD291749A5/de not_active IP Right Cessation
- 1990-01-23 IE IE26090A patent/IE64243B1/en not_active IP Right Cessation
- 1990-01-23 HU HU90239A patent/HU206307B/hu not_active IP Right Cessation
- 1990-01-23 MA MA21999A patent/MA21737A1/fr unknown
- 1990-01-23 DD DD344416A patent/DD300422A5/de unknown
- 1990-01-23 AR AR90315991A patent/AR247206A1/es active
- 1990-01-23 OA OA59728A patent/OA09190A/xx unknown
- 1990-01-23 CA CA002008341A patent/CA2008341C/fr not_active Expired - Fee Related
- 1990-01-23 NO NO900309A patent/NO173992C/no unknown
- 1990-01-23 RU SU904743212A patent/RU2012554C1/ru active
- 1990-01-24 US US07/469,121 patent/US5082859A/en not_active Expired - Fee Related
- 1990-01-24 JP JP2012746A patent/JP2561354B2/ja not_active Expired - Lifetime
- 1990-01-24 PT PT92945A patent/PT92945B/pt not_active IP Right Cessation
- 1990-01-24 TN TNTNSN90008A patent/TNSN90008A1/fr unknown
- 1990-01-24 NZ NZ232226A patent/NZ232226A/xx unknown
- 1990-01-24 CZ CS90341A patent/CZ278567B6/cs not_active IP Right Cessation
- 1990-01-24 SK SK341-90A patent/SK34190A3/sk unknown
- 1990-01-24 YU YU12490A patent/YU48227B/sh unknown
- 1990-01-24 ZA ZA90511A patent/ZA90511B/xx unknown
- 1990-01-24 AU AU48797/90A patent/AU629602B2/en not_active Ceased
-
1993
- 1993-03-30 GE GEAP1993645A patent/GEP19971017B/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
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| AR247206A1 (es) | Un procedimiento de preparacion de derivados de acidos benzocicloalquenil-dihidroxi-alcanoico. | |
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