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ZA892474B - Process for preparing derivatives of baccatine iii and of 10-deacetyl baccatine iii - Google Patents

Process for preparing derivatives of baccatine iii and of 10-deacetyl baccatine iii

Info

Publication number
ZA892474B
ZA892474B ZA892474A ZA892474A ZA892474B ZA 892474 B ZA892474 B ZA 892474B ZA 892474 A ZA892474 A ZA 892474A ZA 892474 A ZA892474 A ZA 892474A ZA 892474 B ZA892474 B ZA 892474B
Authority
ZA
South Africa
Prior art keywords
iii
baccatine iii
deacetyl
preparing derivatives
baccatine
Prior art date
Application number
ZA892474A
Other languages
English (en)
Inventor
Michel Colin
Colin Michel
Daniel Guenard
Guenard Daniel
Francois Gueritte-Voegelein
Gueritte-Voegelein Francois
Pierre Potier
Potier Pierre
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of ZA892474B publication Critical patent/ZA892474B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA892474A 1988-04-06 1989-04-04 Process for preparing derivatives of baccatine iii and of 10-deacetyl baccatine iii ZA892474B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8804513A FR2629819B1 (fr) 1988-04-06 1988-04-06 Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii

Publications (1)

Publication Number Publication Date
ZA892474B true ZA892474B (en) 1989-12-27

Family

ID=9364992

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA892474A ZA892474B (en) 1988-04-06 1989-04-04 Process for preparing derivatives of baccatine iii and of 10-deacetyl baccatine iii

Country Status (13)

Country Link
US (1) US4924012A (xx)
EP (1) EP0336841B1 (xx)
JP (1) JPH0686441B2 (xx)
KR (1) KR970009729B1 (xx)
AT (1) ATE89823T1 (xx)
AU (1) AU618333B2 (xx)
CA (1) CA1308417C (xx)
DE (1) DE68906705T2 (xx)
ES (1) ES2055119T3 (xx)
FR (1) FR2629819B1 (xx)
GR (1) GR3007982T3 (xx)
IL (1) IL89831A (xx)
ZA (1) ZA892474B (xx)

Families Citing this family (138)

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US5015744A (en) * 1989-11-14 1991-05-14 Florida State University Method for preparation of taxol using an oxazinone
FR2658513B1 (fr) * 1990-02-21 1994-02-04 Rhone Poulenc Sante Procede de preparation de l'acide cis-beta-phenylglycidique-(2r,3r).
FR2658510B1 (fr) * 1990-02-21 1992-04-30 Rhone Poulenc Sante Nouveau derive de la beta-phenylisoserine, sa preparation et son emploi.
FR2662440B1 (fr) * 1990-05-22 1992-07-31 Rhone Poulenc Sante Procede de preparation stereoselective de derives de la phenylisoserine.
US5380916A (en) * 1990-11-02 1995-01-10 University Of Florida Method for the isolation and purification of taxane derivatives
MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
FR2679557B1 (fr) * 1991-07-25 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de derives du taxane, nouveaux derives obtenus et compositions pharmaceutiques qui les contiennent.
FR2671799B1 (fr) † 1991-01-17 1993-03-12 Rhone Poulenc Rorer Sa La b-phenylisoserine-(2r, 3s), ses sels, sa preparation et son emploi.
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FR2678930B1 (fr) * 1991-07-10 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
US5481010A (en) * 1991-07-16 1996-01-02 Centre National De La Recherche Scientifique 7-deacetoxy beccatine IV derivative and preparation and use thereof
WO1993002064A1 (fr) * 1991-07-16 1993-02-04 Centre National De La Recherche Scientifique (Cnrs) Nouveau derive de la 7-desacetoxy baccatine iv, sa preparation et son emploi
FR2680506B1 (fr) * 1991-08-19 1994-09-02 Rhone Poulenc Rorer Sa Procede de preparation de derives de la beta-phenylisoserine et leur utilisation.
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US6028205A (en) * 1991-09-23 2000-02-22 Florida State University C2 tricyclic taxanes
US5739362A (en) * 1991-09-23 1998-04-14 Florida State University Taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
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US5728850A (en) * 1991-09-23 1998-03-17 Florida State University Taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
US5227400A (en) * 1991-09-23 1993-07-13 Florida State University Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
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US5229526A (en) * 1991-09-23 1993-07-20 Florida State University Metal alkoxides
US5654447A (en) * 1991-09-23 1997-08-05 Florida State University Process for the preparation of 10-desacetoxybaccatin III
US6005138A (en) * 1991-09-23 1999-12-21 Florida State University Tricyclic taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
US5284865A (en) * 1991-09-23 1994-02-08 Holton Robert A Cyclohexyl substituted taxanes and pharmaceutical compositions containing them
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US6335362B1 (en) 1991-09-23 2002-01-01 Florida State University Taxanes having an alkyl substituted side-chain and pharmaceutical compositions containing them
US5710287A (en) * 1991-09-23 1998-01-20 Florida State University Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
US5489601A (en) * 1991-09-23 1996-02-06 Florida State University Taxanes having a pyridyl substituted side-chain and pharmaceutical compositions containing them
US5990325A (en) 1993-03-05 1999-11-23 Florida State University Process for the preparation of 9-desoxotaxol, 9-desoxobaccatin III and analogs thereof
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US5274124A (en) * 1991-09-23 1993-12-28 Florida State University Metal alkoxides
US5728725A (en) * 1991-09-23 1998-03-17 Florida State University C2 taxane derivaties and pharmaceutical compositions containing them
US5998656A (en) * 1991-09-23 1999-12-07 Florida State University C10 tricyclic taxanes
US5399726A (en) 1993-01-29 1995-03-21 Florida State University Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups
US6018073A (en) * 1991-09-23 2000-01-25 Florida State University Tricyclic taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
US5283253A (en) * 1991-09-23 1994-02-01 Florida State University Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them
US7074945B2 (en) * 1991-09-23 2006-07-11 Florida State University Metal alkoxide taxane derivatives
US6011056A (en) 1991-09-23 2000-01-04 Florida State University C9 taxane derivatives and pharmaceutical compositions containing them
US6495704B1 (en) 1991-09-23 2002-12-17 Florida State University 9-desoxotaxanes and process for the preparation of 9-desoxotaxanes
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Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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FR2601676B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Procede de preparation du taxol et du desacetyl-10 taxol
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol

Also Published As

Publication number Publication date
IL89831A (en) 1992-12-01
ATE89823T1 (de) 1993-06-15
DE68906705D1 (de) 1993-07-01
EP0336841A1 (fr) 1989-10-11
CA1308417C (fr) 1992-10-06
JPH0686441B2 (ja) 1994-11-02
KR890016029A (ko) 1989-11-28
JPH01305077A (ja) 1989-12-08
FR2629819A1 (fr) 1989-10-13
US4924012A (en) 1990-05-08
IL89831A0 (en) 1989-12-15
AU618333B2 (en) 1991-12-19
AU3242689A (en) 1989-10-12
GR3007982T3 (xx) 1993-08-31
DE68906705T2 (de) 1993-09-16
KR970009729B1 (ko) 1997-06-17
FR2629819B1 (fr) 1990-11-16
EP0336841B1 (fr) 1993-05-26
ES2055119T3 (es) 1994-08-16

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