ZA201001015B - (Carboxylalkylene-phenyl)-phenyl-oxalamides, method for the production thereof, and use of same as a medicament - Google Patents

(Carboxylalkylene-phenyl)-phenyl-oxalamides, method for the production thereof, and use of same as a medicament

Info

Publication number: ZA201001015B
Authority: ZA; South Africa
Prior art keywords: phenyl; carboxylalkylene; oxalamides; medicament; production
Prior art date: 2007-09-21

Application number

ZA201001015A

Other languages

English (en)

Inventor

Elisabeth Defossa

Viktoria Dietrich

Guido Haschke

Johanna Kuhlmann

Thomas Klabunde

Siegfried Stengelin

Andreas Herling

Stefan Bartoschek

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-09-21

Filing date

2010-02-11

Publication date

2010-10-27

2010-02-11 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2010-10-27 Publication of ZA201001015B publication Critical patent/ZA201001015B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
- C07C235/80—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms having carbon atoms of carboxamide groups and keto groups bound to the same carbon atom, e.g. acetoacetamides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ZA201001015A 2007-09-21 2010-02-11 (Carboxylalkylene-phenyl)-phenyl-oxalamides, method for the production thereof, and use of same as a medicament ZA201001015B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP07291132		2007-09-21

Publications (1)

Publication Number	Publication Date
ZA201001015B true ZA201001015B (en)	2010-10-27

Family

ID=39111451

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA201001015A ZA201001015B (en)	2007-09-21	2010-02-11	(Carboxylalkylene-phenyl)-phenyl-oxalamides, method for the production thereof, and use of same as a medicament

Country Status (20)

Country	Link
US (2)	US8518875B2 (xx)
EP (1)	EP2203416B1 (xx)
JP (1)	JP5427784B2 (xx)
KR (1)	KR20100061692A (xx)
CN (1)	CN101796017A (xx)
AR (1)	AR068479A1 (xx)
AU (1)	AU2008303976B9 (xx)
CA (1)	CA2700028A1 (xx)
CL (1)	CL2008002742A1 (xx)
CO (1)	CO6260062A2 (xx)
IL (1)	IL204555A0 (xx)
MA (1)	MA31710B1 (xx)
MX (1)	MX2010002461A (xx)
MY (1)	MY149648A (xx)
NZ (1)	NZ584049A (xx)
RU (1)	RU2488578C2 (xx)
TW (1)	TWI439265B (xx)
UY (1)	UY31350A1 (xx)
WO (1)	WO2009039943A1 (xx)
ZA (1)	ZA201001015B (xx)

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CA2785674A1 (en)	2009-12-25	2011-06-30	Mochida Pharmaceutical Co., Ltd.	Novel 3-hydroxy-5-arylisothiazole derivative
WO2011107494A1 (de)	2010-03-03	2011-09-09	Sanofi	Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
US8530413B2 (en)	2010-06-21	2013-09-10	Sanofi	Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en)	2010-07-05	2012-04-16	Sanofi Sa	(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201215387A (en)	2010-07-05	2012-04-16	Sanofi Aventis	Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201221505A (en)	2010-07-05	2012-06-01	Sanofi Sa	Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
RU2013114390A (ru)	2010-08-31	2014-10-10	СНУ Ар энд ДиБи ФАУНДЕЙШН	Применение фетального репрограммирования посредством ppar-дельта-агониста
US9040525B2 (en)	2010-10-08	2015-05-26	Mochida Pharmaceutical Co., Ltd.	Cyclic amide derivative
BR112013027883A2 (pt)	2011-04-27	2017-08-08	Mochida Pharm Co Ltd	novo derivado de 1-óxido de 3-hidroxiisotiazol
CA2834465A1 (en)	2011-04-28	2012-11-01	Mochida Pharmaceutical Co., Ltd.	Cyclic amide derivative
WO2013037390A1 (en)	2011-09-12	2013-03-21	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en)	2011-09-27	2015-10-21	Sanofi	6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013102626A1 (en) *	2012-01-04	2013-07-11	Sanofi	3-[4-(phenylaminooxalylamino)phenyl]hex-4-ynoic acids, process for preparation thereof and use thereof as a medicament
WO2014064215A1 (en)	2012-10-24	2014-05-01	INSERM (Institut National de la Santé et de la Recherche Médicale)	TPL2 KINASE INHIBITORS FOR PREVENTING OR TREATING DIABETES AND FOR PROMOTING β-CELL SURVIVAL
JPWO2015046317A1 (ja) *	2013-09-30	2017-03-09	国立大学法人岡山大学	新規アセチレンアミド誘導体
EP3076959B1 (en)	2013-12-04	2018-07-04	Merck Sharp & Dohme Corp.	Antidiabetic bicyclic compounds
US10059667B2 (en)	2014-02-06	2018-08-28	Merck Sharp & Dohme Corp.	Antidiabetic compounds
ES2805743T3 (es)	2015-03-24	2021-02-15	Inst Nat Sante Rech Med	Método y composición farmacéutica para uso en el tratamiento de la diabetes
KR102586510B1 (ko)	2018-02-13	2023-10-12	길리애드 사이언시즈, 인코포레이티드	Pd-1/pd-l1 억제제
AU2019255750B2 (en)	2018-04-19	2021-10-21	Gilead Sciences, Inc.	PD-1/PD-L1 inhibitors
AU2019301811B2 (en)	2018-07-13	2022-05-26	Gilead Sciences, Inc.	PD-1/PD-L1 inhibitors
JP7158577B2 (ja)	2018-10-24	2022-10-21	ギリアードサイエンシーズ，インコーポレイテッド	Ｐｄ－１／ｐｄ－ｌ１阻害剤
AU2020363377A1 (en)	2019-10-07	2022-04-21	Kallyope, Inc.	GPR119 agonists
CN114728917B (zh) *	2019-12-04	2023-12-08	深圳信立泰药业股份有限公司	草酰胺类衍生物、其制备方法及其在医药上的应用
AU2021228729A1 (en)	2020-02-28	2022-09-22	Kallyope, Inc.	GPR40 agonists
UY39222A (es)	2020-05-19	2021-11-30	Kallyope Inc	Activadores de la ampk
AU2021297323A1 (en)	2020-06-26	2023-02-16	Kallyope, Inc.	AMPK activators

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DE1618197B1 (de) *	1966-02-07	1971-12-09	Ciba Geigy	Verwendung von asymmetrischen Oxalsäure-diarylamiden als Ultraviolettschutzmittel für organische Materialien
FR2727114B1 (fr) *	1994-11-17	1996-12-27	Oreal	Nouveaux filtres solaires, compositions cosmetiques photoprotectrices les contenant et utilisations
EP1052994A2 (en) *	1998-02-02	2000-11-22	Trustees Of Tufts College	Use of dipeptidylpetidase inhibitors to regulate glucose metabolism
US6890568B2 (en) *	1999-05-24	2005-05-10	Grant Pierce	Method for management of blood glucose levels
US6867299B2 (en) *	2000-02-24	2005-03-15	Hoffmann-La Roche Inc.	Oxamide IMPDH inhibitors
HU227197B1 (en) *	2000-10-24	2010-10-28	Richter Gedeon Nyrt	Nmda receptor antagonist carboxylic acid amide derivatives and pharmaceutical compositions containing them
MXPA03010724A (es) *	2001-05-25	2004-03-02	Boehringer Ingelheim Pharma	Compuestos de carbamato y oxamida como inhibidores de la produccion de citocina.
ITRM20020016A1 (it) *	2002-01-15	2003-07-15	Sigma Tau Ind Farmaceuti	Derivati di acidi fenil(alchil)carbossilici e derivati fenilalchileterociclici dionici, loro uso come medicamenti ad attivita' ipoglicemizza
JP4224979B2 (ja) *	2002-04-09	2009-02-18	大正製薬株式会社	インターロイキン１２抑制剤
BR0312023A (pt) *	2002-06-27	2005-03-22	Novo Nordisk As	Composto, composto ativador da glicose cinase, método para evitar a hipoglicemia, uso de um composto, e, composição farmacêutica
US20050124667A1 (en) *	2003-10-30	2005-06-09	Eric Sartori	Oxamide inhibitors of plasminogen activator inhibitor-1

2008
- 2008-09-04 KR KR1020107006034A patent/KR20100061692A/ko not_active Ceased
- 2008-09-04 JP JP2010525227A patent/JP5427784B2/ja not_active Expired - Fee Related
- 2008-09-04 CA CA2700028A patent/CA2700028A1/en not_active Abandoned
- 2008-09-04 WO PCT/EP2008/007218 patent/WO2009039943A1/de not_active Ceased
- 2008-09-04 MX MX2010002461A patent/MX2010002461A/es active IP Right Grant
- 2008-09-04 EP EP08785815.5A patent/EP2203416B1/de active Active
- 2008-09-04 AU AU2008303976A patent/AU2008303976B9/en not_active Ceased
- 2008-09-04 NZ NZ584049A patent/NZ584049A/en not_active IP Right Cessation
- 2008-09-04 CN CN200880105281A patent/CN101796017A/zh active Pending
- 2008-09-04 MY MYPI2010000692A patent/MY149648A/en unknown
- 2008-09-04 RU RU2010115748/04A patent/RU2488578C2/ru not_active IP Right Cessation
- 2008-09-15 CL CL2008002742A patent/CL2008002742A1/es unknown
- 2008-09-18 AR ARP080104056A patent/AR068479A1/es not_active Application Discontinuation
- 2008-09-18 TW TW097135728A patent/TWI439265B/zh not_active IP Right Cessation
- 2008-09-19 UY UY31350A patent/UY31350A1/es not_active Application Discontinuation
2010
- 2010-02-11 ZA ZA201001015A patent/ZA201001015B/xx unknown
- 2010-03-16 CO CO10030971A patent/CO6260062A2/es active IP Right Grant
- 2010-03-16 IL IL204555A patent/IL204555A0/en not_active IP Right Cessation
- 2010-03-16 US US12/724,519 patent/US8518875B2/en active Active
- 2010-03-19 MA MA32711A patent/MA31710B1/fr unknown
2013
- 2013-04-17 US US13/864,622 patent/US20130231388A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20130231388A1 (en)	2013-09-05
WO2009039943A1 (de)	2009-04-02
RU2488578C2 (ru)	2013-07-27
EP2203416B1 (de)	2016-10-26
CA2700028A1 (en)	2009-04-02
IL204555A0 (en)	2010-11-30
MA31710B1 (fr)	2010-09-01
AU2008303976B2 (en)	2013-04-18
CL2008002742A1 (es)	2009-01-16
JP2010539199A (ja)	2010-12-16
TWI439265B (zh)	2014-06-01
NZ584049A (en)	2011-05-27
TW200927088A (en)	2009-07-01
MX2010002461A (es)	2010-03-26
UY31350A1 (es)	2009-04-30
KR20100061692A (ko)	2010-06-08
AU2008303976B9 (en)	2013-09-12
EP2203416A1 (de)	2010-07-07
RU2010115748A (ru)	2011-10-27
AU2008303976A1 (en)	2009-04-02
JP5427784B2 (ja)	2014-02-26
AR068479A1 (es)	2009-11-18
US20100261645A1 (en)	2010-10-14
CO6260062A2 (es)	2011-03-22
MY149648A (en)	2013-09-30
US8518875B2 (en)	2013-08-27
CN101796017A (zh)	2010-08-04

Publication	Publication Date	Title
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