[go: up one dir, main page]

ZA200903533B - Process for the preparation of rosuvastatin - Google Patents

Process for the preparation of rosuvastatin

Info

Publication number
ZA200903533B
ZA200903533B ZA200903533A ZA200903533A ZA200903533B ZA 200903533 B ZA200903533 B ZA 200903533B ZA 200903533 A ZA200903533 A ZA 200903533A ZA 200903533 A ZA200903533 A ZA 200903533A ZA 200903533 B ZA200903533 B ZA 200903533B
Authority
ZA
South Africa
Prior art keywords
rosuvastatin
preparation
Prior art date
Application number
ZA200903533A
Other languages
English (en)
Inventor
Steven Robert Lenger
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39092852&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200903533(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Publication of ZA200903533B publication Critical patent/ZA200903533B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ZA200903533A 2006-12-01 2009-05-21 Process for the preparation of rosuvastatin ZA200903533B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86811106P 2006-12-01 2006-12-01

Publications (1)

Publication Number Publication Date
ZA200903533B true ZA200903533B (en) 2010-03-31

Family

ID=39092852

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200903533A ZA200903533B (en) 2006-12-01 2009-05-21 Process for the preparation of rosuvastatin

Country Status (12)

Country Link
US (1) US20080188657A1 (xx)
EP (1) EP2091923A1 (xx)
JP (1) JP2010511029A (xx)
CN (1) CN101627018A (xx)
AR (1) AR064027A1 (xx)
AU (1) AU2007327013B2 (xx)
CA (1) CA2670456A1 (xx)
CL (1) CL2007003459A1 (xx)
NZ (1) NZ577218A (xx)
TW (1) TW200831469A (xx)
WO (1) WO2008065410A1 (xx)
ZA (1) ZA200903533B (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0011120D0 (en) * 2000-05-09 2000-06-28 Avecia Ltd Process
NL1015744C2 (nl) * 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
SI1417180T1 (sl) 2001-07-13 2007-04-30 Astrazeneca Uk Ltd Priprava aminopirimidinskih spojin
GB0218781D0 (en) * 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
GB0312896D0 (en) * 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
UY28501A1 (es) * 2003-09-10 2005-04-29 Astrazeneca Uk Ltd Compuestos químicos
GB0324791D0 (en) * 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
US7851624B2 (en) 2003-12-24 2010-12-14 Teva Pharamaceutical Industries Ltd. Triol form of rosuvastatin and synthesis of rosuvastatin
GB0428328D0 (en) * 2004-12-24 2005-02-02 Astrazeneca Uk Ltd Chemical process
EP1869005A1 (en) * 2005-04-04 2007-12-26 Unichem Laboratories Limited Process for preparation of calcium salt of rosuvastatin
GB0514078D0 (en) * 2005-07-08 2005-08-17 Astrazeneca Uk Ltd Chemical process
EP2172471B1 (en) 2007-04-18 2013-03-27 Teva Pharmaceutical Industries, Ltd. A process for preparing intermediates of HMG-CoA reductase inhibitors
WO2012011129A2 (en) * 2010-07-22 2012-01-26 Msn Laboratories Limited Novel polymorph of bis[(e)-7-[4-(4-fluorophenyl)-6-iso-propyl-2-[methyl (methylsulfonyl)amino]pyrimidin-5-yl](3r,5s)-3,5-dihydroxyhept-6-enoic acid] calcium salt
JP6562213B2 (ja) * 2013-08-30 2019-08-21 日産化学株式会社 光学活性５−ヒドロキシ−３−ケトエステル類の製造方法
EP3103878A4 (en) 2014-02-06 2017-08-16 API Corporation Rosuvastatin calcium and process for producing intermediate thereof
CN104356119B (zh) * 2014-10-17 2017-05-03 上海应用技术学院 多取代嘧啶类他汀内酯脱水化合物及其用途
CN104628653B (zh) * 2015-01-28 2018-04-03 湖北益泰药业有限公司 合成瑞舒伐他汀钙关键中间体的方法
CN104744377B (zh) * 2015-02-12 2017-04-26 上海弈柯莱生物医药科技有限公司 一种(e)‑3‑[4‑(4‑氟苯基)‑6‑异丙基‑2‑(n‑甲基‑n‑甲磺酰胺基)嘧啶‑5‑基]丙烯醛的制备方法
CN104744378B (zh) * 2015-02-12 2017-10-13 上海弈柯莱生物医药科技有限公司 一种(e)‑3‑[4‑(4‑氟苯基)‑6‑异丙基‑2‑(n‑甲基‑n‑甲磺酰胺基)嘧啶‑5‑基]丙烯醛的合成方法
CN105153040B (zh) * 2015-10-15 2018-04-13 江苏师范大学 瑞舒伐他汀钙新晶型及其制备方法
CN105566228B (zh) * 2015-12-30 2019-01-04 安徽美诺华药物化学有限公司 一种瑞舒伐他汀的合成方法
CN105461636A (zh) * 2015-12-30 2016-04-06 安徽美诺华药物化学有限公司 一种瑞舒伐他汀甲酯的合成方法
CN111718334B (zh) * 2019-03-20 2022-09-30 鲁南制药集团股份有限公司 一种瑞舒伐他汀钙中间体化合物

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9903472D0 (en) * 1999-02-17 1999-04-07 Zeneca Ltd Chemical process
GB0011120D0 (en) * 2000-05-09 2000-06-28 Avecia Ltd Process
NL1015744C2 (nl) * 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
ES2214169T1 (es) * 2001-06-06 2004-09-16 Bristol-Myers Squibb Company Procedimiento de preparacion de sulfonas quirales dioles e inhibidores del dihidroxiacido hmg coa reductasa.
SE0102299D0 (sv) * 2001-06-26 2001-06-26 Astrazeneca Ab Compounds
SI1417180T1 (sl) * 2001-07-13 2007-04-30 Astrazeneca Uk Ltd Priprava aminopirimidinskih spojin
KR100919941B1 (ko) * 2001-11-14 2009-10-05 닛산 가가쿠 고교 가부시키 가이샤 광학활성 옥소헵텐산 에스테르의 제조방법
EP1323717A1 (en) * 2001-12-27 2003-07-02 Dsm N.V. Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives
US6835838B2 (en) * 2002-01-28 2004-12-28 Novartis Ag Process for the manufacture of organic compounds
EP1375493A1 (en) * 2002-06-17 2004-01-02 Dsm N.V. Process for the preparation of an dioxane acetic acid ester
GB0218781D0 (en) * 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
PT1578731E (pt) * 2002-12-16 2010-01-12 Astrazeneca Uk Ltd Processo para a preparação de compostos pirimidina
GB0312896D0 (en) * 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
UY28501A1 (es) * 2003-09-10 2005-04-29 Astrazeneca Uk Ltd Compuestos químicos
GB0321827D0 (en) * 2003-09-18 2003-10-15 Astrazeneca Uk Ltd Chemical compounds
GB0324791D0 (en) * 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
DE10352659B4 (de) * 2003-11-11 2007-09-13 Ratiopharm Gmbh Verfahren zur Herstellung von Statinen und Tetrahydropyranonderivate zur Verwendung in dem Verfahren
WO2005054207A1 (en) * 2003-12-04 2005-06-16 Glenmark Pharmaceuticals Limited Process for the preparation of pyrimidine derivatives
GB0428328D0 (en) * 2004-12-24 2005-02-02 Astrazeneca Uk Ltd Chemical process
CN100351240C (zh) * 2005-01-19 2007-11-28 安徽省庆云医药化工有限公司 瑞舒伐他汀钙的合成方法
GB0514078D0 (en) * 2005-07-08 2005-08-17 Astrazeneca Uk Ltd Chemical process

Also Published As

Publication number Publication date
JP2010511029A (ja) 2010-04-08
TW200831469A (en) 2008-08-01
AU2007327013A1 (en) 2008-06-05
US20080188657A1 (en) 2008-08-07
WO2008065410A1 (en) 2008-06-05
CN101627018A (zh) 2010-01-13
NZ577218A (en) 2011-06-30
AR064027A1 (es) 2009-03-04
CL2007003459A1 (es) 2008-08-22
CA2670456A1 (en) 2008-06-05
EP2091923A1 (en) 2009-08-26
AU2007327013B2 (en) 2011-01-27

Similar Documents

Publication Publication Date Title
ZA200903533B (en) Process for the preparation of rosuvastatin
ZA200905012B (en) Process for the preparation of certain substituted sulfimines
IL198847A0 (en) New process for the preparation of 2-imino-thiazolidin-4-one derivatives
IL188330A0 (en) Processes for the preparation of
IL190135A0 (en) Process for the preparation of pyrimidinedione derivatives
IL196875A0 (en) Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines
ZA200907811B (en) Process for the manufacture of p4o6
EP2117330A4 (en) PROCESS FOR THE PREPARATION OF ANGIOGENIN
ZA200900336B (en) Process for the preparation of diesters
ZA200907191B (en) Process for the preparation of gefitiib
ZA200804264B (en) Process for the preparation of ferri-succinylcasein
IL196481A0 (en) Process for the preparation of levetiracetam
PL1976960T3 (pl) Sposób wytwarzania biooleju napędowego
IL196474A0 (en) Improved process for the preparation of voriconazole
HU0700818D0 (en) Process for the preparation of polyirocyanates of the diphenylmethone series
SI1844036T1 (sl) Postopek za pripravo aripiprazola
EG26332A (en) Process for the preparation of benzonoprons
IL205082A0 (en) Process for the preparation of tetranorlabdane derivatives
IL196602A0 (en) Processes for the preparation of montelukast
GB0910201D0 (en) The preparation method of 2-deoxy-l-ribose
ZA200601910B (en) Process for the preparation of organosilances
GB2464854B (en) Process for the preparation of risperidone
ZA201000802B (en) Process for the preparation of alfuzosin hydrochloride
EP2173695A4 (en) PROCESS FOR THE PREPARATION OF CIS-4-TERT.-BUTYLCYCLOHEXANOL
PL2285780T3 (pl) Sposoby i związki do wytwarzania normorfinanów