ZA200801890B - Novel crystalline form of a pyridazino (4, 5-B) indole derivative - Google Patents

Novel crystalline form of a pyridazino (4, 5-B) indole derivative

Info

Publication number: ZA200801890B
Authority: ZA; South Africa
Prior art keywords: pyridazino; crystalline form; novel crystalline; indole derivative; indole
Prior art date: 2005-08-29

Application number

ZA200801890A

Other languages

English (en)

Inventor

William L Rocco

John D Higgins

Original Assignee

Sanofi Aventis Us Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-08-29

Filing date

2006-08-24

Publication date

2009-11-25

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37546937&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200801890(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2006-08-24 Application filed by Sanofi Aventis Us Llc filed Critical Sanofi Aventis Us Llc

2009-11-25 Publication of ZA200801890B publication Critical patent/ZA200801890B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Psychiatry (AREA)
Dermatology (AREA)
Oncology (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

ZA200801890A 2005-08-29 2006-08-24 Novel crystalline form of a pyridazino (4, 5-B) indole derivative ZA200801890B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US71215305P	2005-08-29	2005-08-29

Publications (1)

Publication Number	Publication Date
ZA200801890B true ZA200801890B (en)	2009-11-25

Family

ID=37546937

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200801890A ZA200801890B (en)	2005-08-29	2006-08-24	Novel crystalline form of a pyridazino (4, 5-B) indole derivative

Country Status (31)

Country	Link
US (1)	US7683062B2 (zh)
EP (1)	EP1924585B1 (zh)
JP (1)	JP5063600B2 (zh)
KR (2)	KR20080050577A (zh)
CN (1)	CN101253176B (zh)
AR (1)	AR057099A1 (zh)
AT (1)	ATE531717T1 (zh)
AU (1)	AU2006285142B2 (zh)
BR (1)	BRPI0615259A2 (zh)
CA (1)	CA2619284C (zh)
CR (1)	CR9723A (zh)
CY (1)	CY1112317T1 (zh)
DK (1)	DK1924585T3 (zh)
EA (1)	EA014164B1 (zh)
EC (1)	ECSP088209A (zh)
ES (1)	ES2375841T3 (zh)
HR (1)	HRP20120073T1 (zh)
IL (1)	IL189276A (zh)
MA (1)	MA30000B1 (zh)
NO (1)	NO20081365L (zh)
NZ (1)	NZ566087A (zh)
PL (1)	PL1924585T3 (zh)
PT (1)	PT1924585E (zh)
RS (1)	RS52318B (zh)
SI (1)	SI1924585T1 (zh)
TN (1)	TNSN08059A1 (zh)
TW (1)	TW200813060A (zh)
UA (1)	UA91716C2 (zh)
UY (1)	UY29771A1 (zh)
WO (1)	WO2007027525A1 (zh)
ZA (1)	ZA200801890B (zh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2678124C (en) *	2003-11-17	2014-10-07	Merck Eprova Ag	Crystalline forms of (6r)-l-erythro-tetrahydrobiopterin dihydrochloride
EP1776365B1 (en) *	2004-06-02	2011-08-03	Sandoz Ag	Meropenem intermediate in crystalline form
EP1928826B1 (en) *	2005-09-21	2013-04-24	4Sc Ag	Sulphonylpyrrole hydrochloride salts as histone deacetylases inhibitors
WO2007053427A2 (en) *	2005-10-31	2007-05-10	Janssen Pharmaceutica N.V.	Novel processes for the preparation of piperazinyl and diazapanyl benzamide derivatives
CA2656057C (en) *	2006-06-16	2012-10-02	H. Lundbeck A/S	Crystalline forms of 4-[2-(4-methylphenylsulfanyl)-phenyl]piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain
RU2496780C2 (ru) *	2006-10-27	2013-10-27	СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи	Твердые формы
EP2085397A1 (en) *	2008-01-21	2009-08-05	Esteve Quimica, S.A.	Crystalline form of abacavir
US7935817B2 (en) *	2008-03-31	2011-05-03	Apotex Pharmachem Inc.	Salt form and cocrystals of adefovir dipivoxil and processes for preparation thereof
AR071318A1 (es) *	2008-04-15	2010-06-09	Basilea Pharmaceutica Ag	Benzhidril ester del acido (6r,7r)-7-{2-(5-amino-[1,2,4]tiadiazol-3-il)-2-[(z)-tritiloxiimino]-acetilamino}-3-[(r)-1'-terc-butoxicarbonil-2-oxo-[1,3']bipirrolidinil-(3e)-ilidenometil]-8-oxo-5-tia-1-aza-biciclo[4.2.0]oct-2-eno-2-carboxilico cristalino; su elaboracion y uso
US8097719B2 (en) *	2008-07-15	2012-01-17	Genesen Labs	Meropenem intermediate in novel crystalline form and a method of manufacture of meropenem
RU2011110241A (ru) *	2008-08-18	2012-09-27	САНОФИ-АВЕНТИС Ю.Эс. ЭлЭлСи (US)	СПОСОБ ПОЛУЧЕНИЯ ПОЛИМОРФА 7-ХЛОР-N,N,5-ТРИМЕТИЛ-4-ОКСО-3-ФЕНИЛ-3,5-ДИГИДРО-4Н-ПИРИДАЗИНО[4,5-b]ИНДОЛ-1-АЦЕТАМИДА
BR112012022910B1 (pt)	2010-03-12	2021-08-10	Omeros Corporation	Compostos inibidores de pde10, composição farmacêutica compreendendo os referidos compostos e uso dos mesmos para tratar distúrbios neurológicos em um animal de sangue quente
JP2013536859A (ja) *	2010-09-01	2013-09-26	アリーナファーマシューティカルズ，インコーポレイテッド	５−ｈｔ２ｃアゴニストの非吸湿性塩
EP2760859A1 (en) *	2011-09-30	2014-08-06	Sunshine Lake Pharma Co., Ltd	Crystalline forms of azilsartan and preparation and uses thereof
NZ716494A (en)	2014-04-28	2017-07-28	Omeros Corp	Processes and intermediates for the preparation of a pde10 inhibitor
NZ716462A (en) *	2014-04-28	2017-11-24	Omeros Corp	Optically active pde10 inhibitor
AU2016250843A1 (en)	2015-04-24	2017-10-12	Omeros Corporation	PDE10 inhibitors and related compositions and methods
JP2018535969A (ja)	2015-11-04	2018-12-06	オメロスコーポレーション	Ｐｄｅ１０阻害剤の固体状態形態
WO2020087031A1 (en)	2018-10-26	2020-04-30	The Research Foundation For The State University Of New York	Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia
CN111303230B (zh) *	2020-03-09	2021-07-13	中国食品药品检定研究院	一种黄体酮共晶物及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2766823B1 (fr) *	1997-07-30	1999-10-08	Synthelabo	Derives de 4-oxo-3,5-dihydro-4h-pyridazino[4,5-b] indole-1-acetamide, leur preparation et leur application en therapeutique
FR2788696B1 (fr) *	1999-01-26	2004-03-05	Synthelabo	Utilisation de derives de pyridazino [4,5-b] indole-1-acetamide pour la preparation de medicaments destines aux maladies du systeme nerveux central
FR2829939B3 (fr)	2001-09-21	2003-11-28	Sanofi Synthelabo	Utilisation du 7-chloro-n,n,5-trimethyl-4-oxo-3-phenyl-3,5- dihydro-4h-pyridazino(4,5-b)indole-1-acetamide pour la preparation de medicaments destines au traitement de la polyarthrite rhumatoide
WO2005034999A2 (en)	2003-10-10	2005-04-21	Bvm Holding Co.	Composition comprising association complex of a pharmaceutical and a poloxamer

2006
- 2006-08-24 EA EA200800716A patent/EA014164B1/ru not_active IP Right Cessation
- 2006-08-24 BR BRPI0615259-7A patent/BRPI0615259A2/pt not_active IP Right Cessation
- 2006-08-24 EP EP06813757A patent/EP1924585B1/en active Active
- 2006-08-24 AT AT06813757T patent/ATE531717T1/de active
- 2006-08-24 ZA ZA200801890A patent/ZA200801890B/xx unknown
- 2006-08-24 DK DK06813757.9T patent/DK1924585T3/da active
- 2006-08-24 CA CA2619284A patent/CA2619284C/en not_active Expired - Fee Related
- 2006-08-24 UA UAA200803953A patent/UA91716C2/ru unknown
- 2006-08-24 AU AU2006285142A patent/AU2006285142B2/en not_active Ceased
- 2006-08-24 CN CN2006800314750A patent/CN101253176B/zh not_active Expired - Fee Related
- 2006-08-24 KR KR1020087004953A patent/KR20080050577A/ko not_active Abandoned
- 2006-08-24 NZ NZ566087A patent/NZ566087A/en not_active IP Right Cessation
- 2006-08-24 SI SI200631252T patent/SI1924585T1/sl unknown
- 2006-08-24 RS RS20120032A patent/RS52318B/sr unknown
- 2006-08-24 WO PCT/US2006/033254 patent/WO2007027525A1/en not_active Ceased
- 2006-08-24 HR HRP20120073TT patent/HRP20120073T1/hr unknown
- 2006-08-24 JP JP2008529130A patent/JP5063600B2/ja not_active Expired - Fee Related
- 2006-08-24 PL PL06813757T patent/PL1924585T3/pl unknown
- 2006-08-24 PT PT06813757T patent/PT1924585E/pt unknown
- 2006-08-24 ES ES06813757T patent/ES2375841T3/es active Active
- 2006-08-24 KR KR1020137018636A patent/KR20130087059A/ko not_active Ceased
- 2006-08-28 AR ARP060103740A patent/AR057099A1/es not_active Application Discontinuation
- 2006-08-29 TW TW095131681A patent/TW200813060A/zh unknown
- 2006-08-29 UY UY29771A patent/UY29771A1/es unknown
2008
- 2008-02-04 IL IL189276A patent/IL189276A/en not_active IP Right Cessation
- 2008-02-06 TN TNP2008000059A patent/TNSN08059A1/en unknown
- 2008-02-11 CR CR9723A patent/CR9723A/es unknown
- 2008-02-14 US US12/031,243 patent/US7683062B2/en not_active Expired - Fee Related
- 2008-02-20 EC EC2008008209A patent/ECSP088209A/es unknown
- 2008-03-14 NO NO20081365A patent/NO20081365L/no not_active Application Discontinuation
- 2008-03-17 MA MA30757A patent/MA30000B1/fr unknown
2012
- 2012-01-26 CY CY20121100092T patent/CY1112317T1/el unknown

Also Published As

Publication number	Publication date
HRP20120073T1 (hr)	2012-07-31
IL189276A0 (en)	2008-08-07
KR20080050577A (ko)	2008-06-09
CN101253176B (zh)	2012-04-18
DK1924585T3 (da)	2012-02-27
CA2619284A1 (en)	2007-03-08
UY29771A1 (es)	2007-03-30
HK1123794A1 (zh)	2009-06-26
BRPI0615259A2 (pt)	2011-05-17
EA014164B1 (ru)	2010-10-29
SI1924585T1 (sl)	2012-09-28
ECSP088209A (es)	2008-06-30
JP5063600B2 (ja)	2012-10-31
JP2009506116A (ja)	2009-02-12
ATE531717T1 (de)	2011-11-15
KR20130087059A (ko)	2013-08-05
MA30000B1 (fr)	2008-12-01
TW200813060A (en)	2008-03-16
WO2007027525A1 (en)	2007-03-08
IL189276A (en)	2012-07-31
US20080139569A1 (en)	2008-06-12
ES2375841T3 (es)	2012-03-06
EA200800716A1 (ru)	2008-08-29
AR057099A1 (es)	2007-11-14
PL1924585T3 (pl)	2012-08-31
NZ566087A (en)	2011-03-31
UA91716C2 (ru)	2010-08-25
CA2619284C (en)	2014-04-29
CN101253176A (zh)	2008-08-27
PT1924585E (pt)	2012-01-19
RS52318B (sr)	2012-12-31
CY1112317T1 (el)	2015-12-09
NO20081365L (no)	2008-04-03
CR9723A (es)	2008-06-18
EP1924585B1 (en)	2011-11-02
AU2006285142B2 (en)	2012-06-14
AU2006285142A1 (en)	2007-03-08
TNSN08059A1 (en)	2009-07-14
EP1924585A1 (en)	2008-05-28
US7683062B2 (en)	2010-03-23

Publication	Publication Date	Title
IL189276A0 (en)	2008-08-07	Novel crystalline form of a pyridazino [4,5-b] indole derivative
ZA200804489B (en)	2009-08-26	1-orthofluorophenyl substituted 1, 2, 5-thiazolidinedione derivatives as PTP-AS inhibitors
SI2395004T1 (sl)	2016-05-31	Derivati piro (2,3-b) piridina kot inhibitorji proteinske kinaze
EP1939202A4 (en)	2010-06-16	NEW COMPOUND OF ADENINE
EP1939201A4 (en)	2010-06-16	NEW ADENINE CONNECTION
EP1939198A4 (en)	2012-02-15	NEW ADENINE CONNECTION
EP1939199A4 (en)	2010-10-20	NEW ADENINE CONNECTION
EP1939200A4 (en)	2010-06-16	NEW ADENINE CONNECTION
SI1710241T1 (sl)	2010-02-26	Intermediatne spojine za pripravo trans-5-kloro-2-metil-2,3,3a, 12b-tetrahidro-1H-dibenz(2,3:6,7)oksepino(4,5-C)pirola
IL178940A0 (en)	2007-03-08	Indole derivative having piperidine ring
IL181766A0 (en)	2007-07-04	A process for the preparation of [1,4,5]-oxadiazepine derivatives
ZA200705216B (en)	2008-09-25	Novel process for the preparation of substituted indoles
IL190729A0 (en)	2008-11-03	Methods for preparing glutamic acid derivatives
AU2006241684A1 (en)	2006-11-09	Novel lactam compound
EP1893625A4 (en)	2012-12-26	PROCESS FOR THE PREPARATION OF 9-DEAZAPURINE DERIVATIVES
ZA200804391B (en)	2009-04-29	Novel vinylogous acids derivatives
IL188371A0 (en)	2008-04-13	Novel piperidine derivatives
IL178069A0 (en)	2006-12-31	Process for preparing n-aryl-piperazine derivatives
IL191546A0 (en)	2008-12-29	Process for the preparation of purified crystalline cci-779
IL186174A0 (en)	2008-01-20	A process for the preparation of 6-0-methyl erythromycin a derivative
GB0506967D0 (en)	2005-05-11	Novel crystalline salt
ZA200709230B (en)	2008-10-29	Novel piperidine derivatives
EP1880995A4 (en)	2010-04-14	METHOD OF SYNTHESIZING AN INDOLE DERIVATIVE COMPRISING A PIPERIDINE CYCLE
TWI365186B (en)	2012-06-01	Indole derivatives
IL187326A0 (en)	2008-04-13	Crystalline form of benzazepinium maleate derivative