ZA200402855B - Novel use of substituted aminomethyl chromans. - Google Patents

Novel use of substituted aminomethyl chromans. Download PDF

Info

Publication number: ZA200402855B
Authority: ZA; South Africa
Prior art keywords: composition; substance; chroman; pharmaceutically acceptable; treatment
Prior art date: 2001-09-19

Application number

ZA200402855A

Other languages

English (en)

Inventor

Henning Boettcher

Gerd Bartoszyk

Frank Weber

Ralf Devant

Hermann Russ

Christoph Seyfried

Original Assignee

Merck Patent Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-19

Filing date

2004-04-15

Publication date

2005-01-14

2004-04-15 Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh

2005-01-14 Publication of ZA200402855B publication Critical patent/ZA200402855B/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyridine Compounds (AREA)
Indole Compounds (AREA)

ZA200402855A 2001-09-19 2004-04-15 Novel use of substituted aminomethyl chromans. ZA200402855B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01122377		2001-09-19

Publications (1)

Publication Number	Publication Date
ZA200402855B true ZA200402855B (en)	2005-01-14

Family

ID=8178662

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200402855A ZA200402855B (en)	2001-09-19	2004-04-15	Novel use of substituted aminomethyl chromans.

Country Status (25)

Country	Link
US (1)	US7618988B2 (zh)
EP (1)	EP1427724B1 (zh)
JP (1)	JP4615857B2 (zh)
KR (1)	KR100912911B1 (zh)
CN (1)	CN100338060C (zh)
AR (1)	AR036677A1 (zh)
AT (1)	ATE325120T1 (zh)
AU (1)	AU2002331229B2 (zh)
BR (1)	BR0212555A (zh)
CA (1)	CA2460696C (zh)
CY (1)	CY1105118T1 (zh)
DE (1)	DE60211186T2 (zh)
DK (1)	DK1427724T3 (zh)
ES (1)	ES2262840T3 (zh)
HU (1)	HUP0401910A3 (zh)
MX (1)	MXPA04002492A (zh)
MY (1)	MY128882A (zh)
PE (1)	PE20030428A1 (zh)
PL (1)	PL208787B1 (zh)
PT (1)	PT1427724E (zh)
RU (1)	RU2322443C2 (zh)
SI (1)	SI1427724T1 (zh)
TW (1)	TWI244391B (zh)
WO (1)	WO2003024960A1 (zh)
ZA (1)	ZA200402855B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10318690B3 (de) *	2003-04-24	2004-11-11	Merck Patent Gmbh	Verfahren zur Herstellung von Nicotinaldehyden
PA8663501A1 (es)	2005-02-17	2006-11-09	Wyeth Wyeth	Derivados de indol, benzotiofeno, benzofurano e indeno cicloalquilcondensados
US8093270B2 (en) *	2005-06-21	2012-01-10	Merck Patent Gmbh	Solid pharmaceutical composition comprising (R)-(−)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chroman
FR2978916B1 (fr)	2011-08-10	2013-07-26	Servier Lab	Composition pharmaceutique solide pour administration buccale d'agomelatine
SG11201406690SA (en) *	2012-04-18	2014-11-27	Contera Pharma Aps	Orally available pharmaceutical formulation suitable for improved management of movement disorders
FR3001894A1 (fr)	2013-02-08	2014-08-15	Servier Lab	Composition pharmaceutique solide pour administration buccale d'agomelatine
KR102443161B1 (ko)	2016-07-11	2022-09-14	콘테라 파르마 에이/에스	아침 운동 불능을 치료하기 위한 박동성 약물 전달 시스템

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5767132A (en) *	1980-10-07	1982-04-23	Nippon Steel Corp	Vertical type continuous annealing furnace having independently moving middle partition plate
DE4135474A1 (de) *	1991-10-28	1993-04-29	Bayer Ag	2-aminomethyl-chromane
SI9300097B (en) *	1992-02-27	2001-12-31	Janssen Pharmaceutica Nv	(benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
DE69433401T2 (de) *	1993-08-19	2004-09-16	Janssen Pharmaceutica N.V.	Gefässverengende dihydrobenzopyranderivate
SI0707007T1 (en) *	1994-10-14	2002-04-30	Merck Patent Gmbh	(R)-(-)-2-(5-(4-fluorophenyl)-3-pyridylmethylaminomethyl)chromane as CNS active agent
US5585388A (en) *	1995-04-07	1996-12-17	Sibia Neurosciences, Inc.	Substituted pyridines useful as modulators of acetylcholine receptors
SI0874849T1 (zh) *	1995-12-21	2001-12-31	Pfizer
US5756521A (en) *	1996-04-03	1998-05-26	American Home Products Corporation	Chroman-2-ylmethylamino derivatives
UA73981C2 (en) *	2000-03-10	2005-10-17	Merck Patent Gmbh	(r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit

2002
- 2002-08-12 AU AU2002331229A patent/AU2002331229B2/en not_active Ceased
- 2002-08-12 AT AT02767363T patent/ATE325120T1/de active
- 2002-08-12 KR KR1020047002484A patent/KR100912911B1/ko not_active Expired - Fee Related
- 2002-08-12 US US10/489,960 patent/US7618988B2/en not_active Expired - Fee Related
- 2002-08-12 ES ES02767363T patent/ES2262840T3/es not_active Expired - Lifetime
- 2002-08-12 WO PCT/EP2002/009001 patent/WO2003024960A1/en not_active Ceased
- 2002-08-12 EP EP02767363A patent/EP1427724B1/en not_active Expired - Lifetime
- 2002-08-12 HU HU0401910A patent/HUP0401910A3/hu unknown
- 2002-08-12 DE DE60211186T patent/DE60211186T2/de not_active Expired - Lifetime
- 2002-08-12 MX MXPA04002492A patent/MXPA04002492A/es active IP Right Grant
- 2002-08-12 JP JP2003528807A patent/JP4615857B2/ja not_active Expired - Fee Related
- 2002-08-12 RU RU2004112190/15A patent/RU2322443C2/ru not_active IP Right Cessation
- 2002-08-12 DK DK02767363T patent/DK1427724T3/da active
- 2002-08-12 CN CNB028183266A patent/CN100338060C/zh not_active Expired - Fee Related
- 2002-08-12 CA CA2460696A patent/CA2460696C/en not_active Expired - Fee Related
- 2002-08-12 SI SI200230351T patent/SI1427724T1/sl unknown
- 2002-08-12 BR BR0212555-2A patent/BR0212555A/pt not_active IP Right Cessation
- 2002-08-12 PT PT02767363T patent/PT1427724E/pt unknown
- 2002-08-12 PL PL369684A patent/PL208787B1/pl not_active IP Right Cessation
- 2002-08-13 TW TW091118183A patent/TWI244391B/zh not_active IP Right Cessation
- 2002-09-16 MY MYPI20023438A patent/MY128882A/en unknown
- 2002-09-17 PE PE2002000915A patent/PE20030428A1/es not_active Application Discontinuation
- 2002-09-18 AR ARP020103509A patent/AR036677A1/es unknown
2004
- 2004-04-15 ZA ZA200402855A patent/ZA200402855B/en unknown
2006
- 2006-07-28 CY CY20061101061T patent/CY1105118T1/el unknown

Also Published As

Publication number	Publication date
MY128882A (en)	2007-02-28
CN1714089A (zh)	2005-12-28
HUP0401910A3 (en)	2011-02-28
KR20040044461A (ko)	2004-05-28
US20060229339A1 (en)	2006-10-12
DK1427724T3 (da)	2006-08-21
EP1427724B1 (en)	2006-05-03
MXPA04002492A (es)	2004-05-31
RU2004112190A (ru)	2005-05-10
ATE325120T1 (de)	2006-06-15
PL208787B1 (pl)	2011-06-30
EP1427724A1 (en)	2004-06-16
PL369684A1 (en)	2005-05-02
CN100338060C (zh)	2007-09-19
DE60211186D1 (de)	2006-06-08
TWI244391B (en)	2005-12-01
ES2262840T3 (es)	2006-12-01
DE60211186T2 (de)	2007-01-18
AU2002331229B2 (en)	2008-05-15
PT1427724E (pt)	2006-09-29
RU2322443C2 (ru)	2008-04-20
JP4615857B2 (ja)	2011-01-19
SI1427724T1 (sl)	2006-10-31
CY1105118T1 (el)	2009-11-04
BR0212555A (pt)	2004-10-19
CA2460696A1 (en)	2003-03-27
PE20030428A1 (es)	2003-05-24
CA2460696C (en)	2011-01-11
KR100912911B1 (ko)	2009-08-20
JP2005527476A (ja)	2005-09-15
AR036677A1 (es)	2004-09-29
US7618988B2 (en)	2009-11-17
WO2003024960A1 (en)	2003-03-27
HUP0401910A2 (hu)	2005-01-28

Publication	Publication Date	Title
EP1427724B1 (en)	2006-05-03	Novel use of substituted aminomethyl chromans
AU2002331229A1 (en)	2003-06-05	Novel use of substituted aminomethyl chromans
CA2455621C (en)	2010-11-16	Use of (r/s)-(-/+) or (s)-(+)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chromane for the treatment of extrapyramidal movement disorders
CA2467081A1 (en)	2003-05-22	Pyrazole derivatives as psychopharmaceuticals
AU2002355170A1 (en)	2003-05-29	Novel use of 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane and its physiologically acceptable salts
EP1299099B1 (en)	2005-10-26	Novel use of (r)-(-)-2- 5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane and its physiologically acceptable salts
AU2002331220B2 (en)	2007-06-07	Novel use of substituted aminomethyl chromans for the treatment of movement disorder and of adverse effects induced by drugs administered to treat extrapyramidal movement disorders
AU2002331220A1 (en)	2003-06-19	Novel use of substituted aminomethyl chromans for the treatment of movement disorder and of adverse effects induced by drugs administered to treat extrapyramidal movement disorders
HK1084385A1 (zh)	2006-07-28	取代的氨甲基苯并二氢吡喃的新用途
HK1084385B (zh)	2008-06-06	取代的氨甲基苯并二氢吡喃的新用途
WO2003074518A1 (en)	2003-09-12	Thiazole derivatives and their use d2- and 5-ht1a-receptor ligands
ZA200401592B (en)	2005-01-26	Novel use of 2-[5- (4-fluorophenyl)-3-pyridylmethylaminomethyl} -chromane and its physiologically acceptable salts