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WO2025178013A1 - Cathéter à électrode - Google Patents

Cathéter à électrode

Info

Publication number
WO2025178013A1
WO2025178013A1 PCT/JP2025/005340 JP2025005340W WO2025178013A1 WO 2025178013 A1 WO2025178013 A1 WO 2025178013A1 JP 2025005340 W JP2025005340 W JP 2025005340W WO 2025178013 A1 WO2025178013 A1 WO 2025178013A1
Authority
WO
WIPO (PCT)
Prior art keywords
electrode
tube
catheter
slits
longitudinal axis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/JP2025/005340
Other languages
English (en)
Japanese (ja)
Inventor
清文 ▲高▼橋
雄起 向井
太郎 近藤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaneka Corp
Original Assignee
Kaneka Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaneka Corp filed Critical Kaneka Corp
Publication of WO2025178013A1 publication Critical patent/WO2025178013A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/28—Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
    • A61B5/283—Invasive
    • A61B5/287—Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]

Definitions

  • the cylindrical electrode located on the outside of the distal portion of the catheter tube has slits, and the extension direction of these slits has a circumferential component. Therefore, by observing how open the slits are, it is possible to determine the degree of curvature of the distal portion of the catheter in which the electrodes are located. Furthermore, by controlling the number of electrodes located in the distal portion of the catheter and the number and shape of the slits in the electrodes, it is possible to form areas in the distal portion of the catheter that are easier to bend and areas that are less likely to bend. This makes it possible to arbitrarily design the ease of bending of the distal portion of the catheter, making it easier to obtain an electrode catheter that is suitable for the treatment subject.
  • the distal portion of the catheter can bend flexibly.
  • the cylindrical electrode located on the outside of the distal portion of the tube has a slit, and the extension direction of the slit has a circumferential component, making it easy for the electrode to bend to follow the curvature of the tube. This is because, when a cylindrical electrode is bent, the portion of the cylindrical wall of the electrode that is on the inside of the bend contracts and the portion that is on the outside of the bend expands.
  • the electrode 20 can be connected to a conductor 30 by passing the conductor 30 through a side hole 11 in the side wall of the tube 10.
  • the shape of the side hole 11 when viewed from the side of the tube 10 is not particularly limited as long as it allows the conductor 30 to pass through, but it can be circular or rectangular, for example.
  • the method for forming the side hole 11 is not particularly limited, but examples include piercing the side wall of the tube 10 with a sharp rod-shaped member such as an awl, or irradiating it with laser light.
  • the conductor 30 and electrode 20 can be connected by methods such as laser welding, resistance welding, or bonding with an adhesive.
  • the conductor 30 may be directly connected to the electrode 20, or, although not shown, may be indirectly connected to the electrode 20 via another conductive member that has conductivity between the conductor 30 and the electrode 20.
  • the electrode catheter 100 may have a distal tip 60.
  • the distal tip 60 include a hollow tube member connected to the distal end of the tube 10, a hemispherical member, a lid-shaped member, or other member.
  • the hemispherical member or lid-shaped member may have a through-hole formed therein through which a guidewire can be inserted.
  • the material that constitutes the distal tip 60 can refer to the material that constitutes the tube 10 described above.
  • the distal tip 60 can be made to function as a distal electrode by forming it from the material that constitutes the electrode 20.
  • a slit 23 has a component in the circumferential direction z
  • the extension direction of the slit 23 may have a 100% circumferential direction z component, or may have a circumferential direction z component and a longitudinal axis direction x component.
  • a slit 23 has a component in the longitudinal axis direction x
  • the length of the slit 23 in the extension direction may be shorter, the same as, or longer than the length of the electrode 20 in the circumferential direction z.
  • the cuts in the slits 23 are formed using a processing machine such as a micromachining machine, and the width of the opening perpendicular to the extension direction of the cuts in the slits 23 is preferably very short compared to the length of the electrode 20 in the longitudinal axis direction x.
  • the slits 23 have openings 23g as shown in Figure 7, and it is preferable that the openings 23g have a width perpendicular to the extension direction of the cuts.
  • the width of the openings 23g can vary depending on the degree of curvature of the electrode 20, but for example, it is preferable that the length of the electrode 20 in the longitudinal axis direction x is 1 to 5 mm, while the width of the openings 23g is 10 to 100 ⁇ m. This allows the electrode 20 to efficiently apply voltage and measure potential while providing the slits 23 in the electrode 20.
  • the degree of curvature of the tube 10, i.e., the degree of curvature of the distal portion of the electrode catheter 100 can be determined, making it possible to improve the accuracy of treatment and examination, such as by ensuring sufficient contact of the distal portion of the electrode catheter 100 with the target tissue.
  • the length from the proximal end 20p of the electrode 20 to the slit 23 located closest to the proximal end 20p is preferably longer than the length from the slit 23 to the adjacent slit 23, and the length from the distal end 20d of the electrode 20 to the slit 23 located closest to the distal end 20d is preferably longer than the length from the slit 23 to the adjacent slit 23.
  • This increases the rigidity of the end of the electrode 20, preventing the opening 23g from opening more than necessary.
  • the electrode 20 preferably has slits 23 formed in a cylindrical member, or the slits may be formed in a ring-shaped member made of plate-like material. It is preferable that the electrode 20 is not a coil formed by winding wire.
  • the slits 20 do not form irregularities on the outer surface of the electrode 20 that are greater than half the thickness of the electrode 20. It is more preferable that the slits 20 do not form irregularities on the outer surface of the electrode 20 that are greater than one-third the thickness of the electrode 20, and even more preferable that the slits 20 do not form irregularities that are greater than one-quarter the thickness of the electrode 20.
  • the bendability of the tube 10 can be controlled by arranging more bendable electrodes 20 in portions of the tube 10 that are desired to be more bendable in the longitudinal axis direction x, and less bendable electrodes 20 in portions that are not desired to bend more.
  • a more bendable electrode 20 can be obtained by increasing the number of slits 23, increasing the circumferential z component of the extension direction of the slits 23, etc.
  • a less bendable electrode 20 can be obtained by not providing slits 23, reducing the number of slits 23, or reducing the circumferential z component of the extension direction of the slits 23, etc.
  • the electrode catheter 100 may include electrodes 20 that do not have slits 23.
  • the electrode catheter 100 only needs to have at least one cylindrical electrode 20 arranged on the outside of the distal portion of the tube 10 that has a slit 23.
  • the ease of bending of the tube 10 can be adjusted by increasing the spacing between the multiple electrodes 20 in the longitudinal axis direction x of the tube 10 in areas where more bending is desired, and decreasing the spacing between the multiple electrodes 20 in the longitudinal axis direction x of the tube 10 in areas where less bending is desired.
  • the slits 23 are preferably formed in a spiral shape in the circumferential direction z.
  • the spiral shape allows the slits 23 to be arranged throughout the entire circumferential direction z.
  • multiple slits 23 extending in the circumferential direction z can be arranged in line in the longitudinal axis direction x in a side view of the electrode 20. This makes it easier for the electrode 20 to bend in accordance with the curvature of the tube 10, regardless of the direction in the circumferential direction z in which the tube 10 is bent.
  • an electrode 20 having slits 23 formed in a spiral shape in the circumferential direction z differs from a coil formed by winding wire.
  • a gap is formed between each turn of wire.
  • a gap is formed between each turn of wire when a tensile force is applied to the coil.
  • the length of the coil in the longitudinal direction from one end of the coil to the gap closest to that end and the length from the other end of the coil to the gap closest to that end depend on the thickness of the wire forming the coil.
  • an electrode 20 having slits 23 formed in a spiral shape in the circumferential direction z does not have a structure formed by winding wire, and the slits 23 can be located at any position regardless of the thickness or outer diameter of the electrode 20.
  • the separation distance in the longitudinal direction x between multiple slits 23 extending in the circumferential direction z that are arranged side by side in the longitudinal direction x in a side view of the electrode 20 may be the same as shown in FIG. 8, or may be different as shown in FIG. 9.
  • This separation distance can be said to be the pitch of the spirally formed slits 23, and the pitch of the spirally formed slits 23 may be the same or different in the longitudinal direction x.
  • the electrode 20 in the longitudinal axis direction x, has one or more first portions 21 in which slits 23 are formed and two or more second portions 22 in which no slits 23 are formed, and it is preferable that the slits 23 are formed so that the first portions 21 have engaging portions 23e. This prevents the electrode 20 from stretching too much in the longitudinal axis direction x, making it easier to control the degree of curvature of the electrode 20.
  • the first portion 21 is a portion in which the slits 23 exist in a band-shaped region in the circumferential direction z
  • the second portion 22 is a portion in which the slits 23 do not exist in a band-shaped region in the circumferential direction z.
  • one slit 23 may be formed in one first portion 21 as shown in Figures 11, 12, and 17, or multiple slits 23 may be formed in one first portion 21 as shown in Figures 15, 16, 18, and 19. It is preferable that the first portion 21 and the second portion 22 are arranged side by side in the longitudinal axis direction x.
  • the slits 23 are formed in a spiral shape as shown in Figures 13 and 14, in a side view of the electrode 20, multiple slits 23 are formed at intervals in the longitudinal axis direction x as shown in Figure 14, and a band-like region in the circumferential direction z in which no slits 23 exist between adjacent slits 23 may be formed, as shown by the dashed dotted line in Figure 14.
  • the engaging portions 23e can be arranged so that the trapezoids engage with each other.
  • the cuts forming the slits 23 have a circumferential extending portion 23z whose main extension direction is the circumferential direction z and a longitudinal extending portion 23x whose main extension direction is the longitudinal direction x, and it is preferable that the angle ⁇ enclosed by the circumferential extending portion z and the longitudinal extending portion x is an acute angle.
  • the engaging portions 23e may be provided so that circular shapes engage with each other.
  • the engaging portions 23e may be provided so that any shape can engage with each other.
  • the engaging portion 23e restrict the movement of the second portions 22 at both ends of the first portion 21 in which the slit 23 having the engaging portion 23e is formed, away from each other in the longitudinal axis direction x.
  • the engaging portion 23e it is also possible to configure the second portions 22 at both ends of the first portion 21 to be allowed to move away from each other to a certain extent, and the degree of this allowance can control the ease with which the electrode 20 bends.
  • Such a configuration can be achieved by increasing the gap of the slit 23 in which the engaging portion 23e is provided to a certain extent.
  • the engagement portion 23e may restrict movement in the longitudinal axis direction x, while allowing movement in the radial direction y. This allows the engagement portion 23e to shift in the radial direction y, allowing the electrode 20 to bend in accordance with the curvature of the tube 10.
  • the engagement portions 23e are preferably formed so that they are aligned in the circumferential direction z. This makes it easier to control the movement of the second portions 22 at both ends of the first portion 21 as they move away from each other.
  • the electrode 20 has one or more first portions 21 in which slits 23 are formed and two or more second portions 22 in which slits 23 are not formed, and the second portions 22 are preferably arranged at the proximal and distal ends of the electrode 20. It is easy to connect a conductor 30 to the second portions 22 in which slits 23 are not formed, and since the second portions 22 are arranged at both ends of the electrode 20, it is easy to connect the conductor 30 to the ends of the electrode 20. This makes it easy to connect the conductor 30 to the electrode 20, while also making it easier to observe the degree of curvature of the electrode 20 by observing the degree of opening of the slits 23 in the first portions 21 arranged in the center of the electrode 20.
  • the slits 23 are preferably formed so as to align with the longitudinal axis direction x when viewed from the side of the electrode 20. This makes it easier for the first portion 21 to bend.
  • the first portion 21 may be formed so that the engagement portions 23e are aligned in the longitudinal axis direction x when viewed from the side of the electrode 20. This makes it easier to control the movement of the second portions 22 at both ends of the first portion 21 in directions away from each other.
  • the electrode 20 has two or more first portions 21 and three or more second portions 22 arranged in the longitudinal axis direction x. This allows for a configuration in which a second portion 22 without a slit 23 is located between two first portions 21 with slits 23 formed therein, making it easier to control the degree of curvature of the electrode 20 in the longitudinal axis direction x.
  • first portions 21 and three or more second portions 22 are arranged on the electrode 20 in the longitudinal axis direction x
  • the first portions 21 are formed symmetrically in a side view of the electrode 20, i.e., when the electrode 20 is viewed from a direction perpendicular to the longitudinal axis direction x. This allows the degree of curvature of the electrode 20 to be symmetrical.
  • the length of the first portion 21 in the longitudinal direction x can be adjusted, for example, by changing the number of cuts forming the slits 23 arranged in the longitudinal direction x.
  • the number of cuts can be counted as one continuous cut that is continuous in the circumferential direction z when viewed from the side of the electrode 20.
  • the length of the first portion 21 in the longitudinal direction x can be adjusted by changing the length of one slit 23 extending in the longitudinal direction x.
  • two or more first portions 21 with slits 23 formed therein and three or more second portions 22 without slits 23 are arranged in the longitudinal axis direction x of the electrode 20, and the slits 23 are formed so that the first portions 21 have engaging portions 23e, and it is preferable that the engaging portions 23e in the two or more first portions 21 have different sizes.
  • the engaging portions 23e it is possible to change the degree to which the second portions 22 at both ends of the first portion 21 are restricted from moving away from each other, and therefore, by making the engaging portions 23e of the two or more first portions 21 different in size, it becomes easier to control the ease with which the electrode 20 bends along the longitudinal axis direction x.
  • Electrode 20d Distal end of electrode 20p: Proximal end of electrode 21: First portion 22: Second portion 23: Slit 23a: Starting point 23b: Ending point 23e: Engagement portion 23g: Opening 23x: Longitudinal axis extending portion 23z: Circumferential extending portion 30: Conductor 40: Conductor tube 41: Connector 50: Handle 51: Guidewire tube 52: Guidewire port 60: Distal tip 70: Inner tube 100: Electrode catheter

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Pathology (AREA)
  • Plasma & Fusion (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

L'invention concerne un cathéter à électrode qui permet d'évaluer facilement le degré de courbure d'une partie pointe de cathéter lorsque celui-ci est inséré dans une cavité corporelle, et qui permet de se conformer facilement à la forme de la cavité corporelle par ajustement la souplesse de la partie pointe de cathéter.　Ce cathéter à électrode a une direction d'axe longitudinal x et une direction circonférentielle, et comprend une extrémité distale et une extrémité proximale dans la direction d'axe longitudinal x Le cathéter à électrode comprend : un tube (10) ayant une lumière s'étendant dans la direction d'axe longitudinal x ; une électrode cylindrique (20) disposée à l'extérieur de la partie distale du tube (10) ; et un conducteur s'étendant dans la lumière du tube (10) et relié à l'électrode (20). L'électrode (20) comporte une fente (23), et la direction d'extension de la fente (23) comporte une composante dans la direction circonférentielle.
PCT/JP2025/005340 2024-02-20 2025-02-18 Cathéter à électrode Pending WO2025178013A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2024023979 2024-02-20
JP2024-023979 2024-02-20

Publications (1)

Publication Number Publication Date
WO2025178013A1 true WO2025178013A1 (fr) 2025-08-28

Family

ID=96847190

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2025/005340 Pending WO2025178013A1 (fr) 2024-02-20 2025-02-18 Cathéter à électrode

Country Status (1)

Country Link
WO (1) WO2025178013A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000500363A (ja) * 1995-11-13 2000-01-18 イーピー テクノロジーズ，インコーポレイテッド 長い損傷を形成するための可撓性組織切除要素
US6493590B1 (en) * 2000-02-09 2002-12-10 Micronet Medical, Inc. Flexible band electrodes for medical leads
JP3161030U (ja) * 2007-05-23 2010-07-22 アーヴィン・バイオメディカル・インク 可撓性先端部を備えたアブレーションカテーテル

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000500363A (ja) * 1995-11-13 2000-01-18 イーピー テクノロジーズ，インコーポレイテッド 長い損傷を形成するための可撓性組織切除要素
US6493590B1 (en) * 2000-02-09 2002-12-10 Micronet Medical, Inc. Flexible band electrodes for medical leads
JP3161030U (ja) * 2007-05-23 2010-07-22 アーヴィン・バイオメディカル・インク 可撓性先端部を備えたアブレーションカテーテル

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