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WO2018036302A1 - Composition fongicide - Google Patents

Composition fongicide Download PDF

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Publication number
WO2018036302A1
WO2018036302A1 PCT/CN2017/093018 CN2017093018W WO2018036302A1 WO 2018036302 A1 WO2018036302 A1 WO 2018036302A1 CN 2017093018 W CN2017093018 W CN 2017093018W WO 2018036302 A1 WO2018036302 A1 WO 2018036302A1
Authority
WO
WIPO (PCT)
Prior art keywords
sulfonate
composition according
active component
acetaminophen
mbit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2017/093018
Other languages
English (en)
Chinese (zh)
Inventor
仲汉根
季自华
季红进
花伟
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangsu Huifeng Agrochemical Co Ltd
Original Assignee
Jiangsu Huifeng Agrochemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Huifeng Agrochemical Co Ltd filed Critical Jiangsu Huifeng Agrochemical Co Ltd
Publication of WO2018036302A1 publication Critical patent/WO2018036302A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines

Definitions

  • the present invention relates to the field of agricultural plant protection, and more particularly to a bactericidal composition having improved properties, and more particularly to a bactericidal composition comprising benzisothiazolinones and acetem and its derivatives.
  • Benzoisothiazolinones are a new type of broad-spectrum fungicide mainly used for the prevention and treatment of various bacterial and fungal diseases such as cereal crops, vegetables and fruits.
  • the mechanism of bactericidal action mainly includes destroying the nuclear structure of the pathogen, causing it to lose the heart part and failing to death and interfering with the metabolism of the pathogenic cells, causing its physiological disorder and ultimately leading to death. It can effectively protect plants from pathogens in the early stage of disease occurrence. Increasing the dosage after disease occurrence can obviously control the spread of pathogens, thus achieving the dual functions of protection and eradication.
  • Ethirol and its derivative acetaminophen sulfonate are endogenous heterocyclic fungicides, mainly used for controlling apples, strawberries, watermelons, cucumbers, grapes, greenhouse roses and strawberries. powdery mildew. Its bactericidal effect has a strong killing effect on mycelium, conidia, fertilized silk, etc., and can strongly inhibit the formation of spores, block the source of spore reinfection, and the bactericidal effect is comprehensive and thorough. For crops that have already developed disease, they can play a good therapeutic role, can eliminate pathogens that have invaded plants, and can significantly inhibit the spread of pathogens without cross-resistance.
  • the object of the present invention is to solve the resistance of the bactericide in practical application and the problem of soil residue, and to screen out the fungicides with different sterilization principles to obtain a new fungicide composition, so as to improve the control effect of the bactericide and delay the resistance.
  • Sexual production reducing the amount of application, reducing the cost of prevention.
  • Another object of the present invention is to provide a process for the preparation of a bactericidal composition comprising two active ingredients A and B and for the control of crop diseases in the agricultural sector.
  • the object of the invention can be achieved by the following measures:
  • a synergistic fungicidal composition comprising two active components A and B, wherein the active component Component A is a structural compound of formula (I) and active component B is acetem and its derivatives.
  • R is selected from H or a C 1 - C 8 alkyl group.
  • the C 1 -C 8 alkyl group in the present invention means a linear or branched alkyl group having 1 to 8 carbon atoms, and includes a C 1 alkyl group (e.g., methyl group) and a C 2 alkyl group (e.g., ethyl group). , C 3 alkyl (such as n-propyl, isopropyl), C 4 alkyl (such as n-butyl, isobutyl, tert-butyl, sec-butyl), C 5 alkyl (such as n-pentyl, etc.) , C 6 alkyl, C 7 alkyl, C 8 alkyl. It includes, but is not limited to, C 1 -C 6 alkyl, C 1 -C 5 alkyl, C 1 -C 4 alkyl, and the like.
  • R is selected from H or a C 1 -C 4 alkyl group.
  • R is selected from the group consisting of H, -CH 3 or -C 4 H 9 .
  • A is 1,2-benzisothiazolin-3-one (abbreviated as BIT in the specification).
  • R is -CH 3
  • A is 2-methyl-1,2-benzisothiazolin-3-one (abbreviated as MBIT in the specification).
  • R is -C 4 H 9
  • A is 2-butyl-1,2-benzisothiazolin-3-one
  • the "butyl” in the formula is preferably n-butyl ( In the specification, it is referred to as BBIT).
  • the pyrithione derivative of the active ingredient B may be various derivatives of the prior art, including but not limited to, acetaminophen sulfonate.
  • the inventors have found through experiments that the composition of the present invention is effective for controlling bacterial or fungal diseases of crops, and more importantly, the application amount is reduced and the use cost is lowered.
  • the compounds containing component A and component B have different structural types and different mechanisms of action. The combination of the two can expand the bactericidal spectrum, and can delay the generation and development of pathogen resistance to a certain extent, and component A and group There is no cross-resistance between points B.
  • the weight ratio between the two components in the bactericide composition of the present invention is from 1:1 to 30.
  • the weight ratio between the components of component A and component B can be further optimized to 1:5-25.
  • the weight ratio between the two components of A and B can be arbitrarily adjusted within the range of the following ratios: 1:1, 1:2, 1:3, 1:4, 1:5. , 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:16, 1:17, 1 :18, 1:19, 1:20, 1:21, 1:22, 1:23, 1:24, 1:25, 1:26, 1:27, 1:28, 1:29, 1:30 It is also possible to select within the range consisting of any two of the above ratios, which can be understood as a weight ratio or a molar ratio.
  • composition of the present invention can be made into a pesticide-acceptable dosage form from the active ingredient and agrochemical adjuvant or adjuvant. Further, the composition comprises from 2 to 80% by weight of the active ingredient and from 98 to 20% by weight of the pesticide adjuvant to form a pesticide-acceptable dosage form.
  • the present invention provides the use of a bactericidal composition comprising component A and component B for controlling crop diseases in the agricultural sector, in particular for controlling fungi or bacteria of certain crops.
  • composition may specifically comprise an agrochemical adjuvant or an auxiliary such as one or more of a carrier, a solvent, a dispersing agent, a wetting agent, an adhesive, a thickener, a binder, a surfactant or a fertilizer.
  • auxiliary such as one or more of a carrier, a solvent, a dispersing agent, a wetting agent, an adhesive, a thickener, a binder, a surfactant or a fertilizer.
  • auxiliary such as one or more of a carrier, a solvent, a dispersing agent, a wetting agent, an adhesive, a thickener, a binder, a surfactant or a fertilizer.
  • auxiliary such as one or more of a carrier, a solvent, a dispersing agent, a wetting agent, an adhesive, a thickener, a binder, a surfactant or a fertilizer.
  • Common auxiliaries can be mixed during the application.
  • auxiliaries or auxiliaries may be solid or liquid, they are usually materials commonly used in the processing of dosage forms, such as natural or regenerated minerals, solvents, dispersants, wetting agents, adhesives, thickeners, binders. .
  • the method of application of the compositions of the invention comprises the use of the compositions of the invention for aerial parts of plants, in particular leaves or foliage. You can choose to soak or apply to the surface of the control object.
  • the frequency of administration and the amount administered will depend on the biological and climatic conditions of the pathogen.
  • the plant growth site such as rice fields, may be wetted with a liquid formulation of the composition, or the composition may be applied to the soil in solid form, such as in the form of granules (soil application), the composition may be passed from the soil to the plant through the roots of the plant. In vivo (systemic action).
  • composition of the present invention can be prepared into various pesticide-acceptable dosage forms including, but not limited to, emulsifiable concentrates, suspending agents, wettable powders, water-dispersible granules, powders, granules, aqueous preparations, aqueous emulsions, microemulsions, poison baits.
  • the dosage form of the invention employs a wettable powder, a suspending agent, a water-dispersible granule, an aqueous emulsion or a microemulsion.
  • the compositions may be applied by spraying, misting, dusting, spreading or pouring, and the like.
  • composition of the present invention can be prepared into various dosage forms by a known method, and the active ingredient and the auxiliary agent, such as a solvent, a solid carrier, and, if necessary, can be uniformly mixed and ground together with the surfactant to prepare a desired preparation. Dosage form.
  • the above solvent may be selected from aromatic hydrocarbons, preferably containing from 8 to 12 carbon atoms, such as a mixture of xylenes or substituted benzenes, phthalates such as dibutyl phthalate or dicaprylic acid, aliphatic hydrocarbons such as rings.
  • aromatic hydrocarbons preferably containing from 8 to 12 carbon atoms, such as a mixture of xylenes or substituted benzenes, phthalates such as dibutyl phthalate or dicaprylic acid, aliphatic hydrocarbons such as rings.
  • Alkenes or paraffins, alcohols and glycols and their ethers and esters such as ethanol, ethylene glycol, ethylene glycol monomethyl
  • ketones such as cyclohexanone
  • highly polar solvents such as N-methyl-2 Pyrrolidone, dimethyl sulfoxide or dimethylformamide
  • vegetable or vegetable oils such as soybean oil.
  • the above solid carriers are typically natural mineral fillers such as talc, kaolin, montmorillonite or activated clay.
  • a highly dispersible silicic acid or a highly dispersible adsorbent polymer carrier such as a particulate adsorbent carrier or a non-adsorbing carrier, and a suitable particulate adsorbent carrier is porous, such as floating. Stone, bentonite or bentonite; suitable non-adsorbing carriers such as calcite or sand.
  • a large amount of pre-granulated materials of inorganic or organic nature can be used as a carrier, in particular dolomite.
  • Suitable surfactants are lignosulfonic acid, naphthalenesulfonic acid, phenolsulfonic acid, alkaline earth metal or amine salts, alkylarylsulfonates, alkyl groups Sulfates, alkyl sulfonates, fatty alcohol sulphates, fatty acids and sulfated fatty alcohol glycol ethers, as well as condensates of sulfonated naphthalene and naphthalene derivatives with formaldehyde, naphthalene or naphthalene sulfonic acid with phenol and formaldehyde Condensate, polyoxyethylene octyl phenyl ether, ethoxylated isooctyl phenol, octyl phenol, nonyl phenol, alkyl aryl polyglycol ether, tributyl benzene poly
  • the active ingredient A can be first dissolved in certain specific basic substances to form a benzisothiazolin metal salt.
  • suitable basic substances include: alkali metal carbonates, alkali metal hydrogens Oxide (such as sodium hydroxide, potassium hydroxide), alkali metal alkoxy carbonate, alkali metal alkoxide or magnesium methoxide.
  • the two active ingredients in the compositions of the present invention exhibit synergistic effects, the activity of which is more pronounced than the expected sum of activity using a single compound, and the individual activity of a single compound.
  • the synergistic effect is manifested by allowing for a reduced application rate, a broader fungicidal control profile, quicker effect, longer lasting control effect, better control of plant harmful fungi by only one or a few applications, and broadening of possible application. Intervals. These properties are particularly desirable in the practice of plant fungi control.
  • the fungicide composition of the invention can be applied to the agricultural field for controlling crop diseases, and the crop diseases here are especially banana leaf spot, wheat rust, potato early blight, tobacco wild blight, rice sheath blight or tomato bacterial angular spot disease Wait.
  • the diseases to which the composition of the present invention can be applied are not limited to the foregoing, and the specific diseases targeted by the present invention include, but are not limited to, wheat diseases (eg, wheat scab, wheat powdery mildew, wheat rust, etc.), rice diseases (such as: rice sheath blight, rice blast disease, rice blast, rice bacterial streaks, etc.), corn diseases (such as: corn smut, corn big spot, corn spot), cucumber diseases (such as: Cucumber downy mildew, cucumber powdery mildew, cucumber anthracnose, cucumber bacterial angular leaf spot, etc., tomato diseases (such as tomato anthracnose, tomato gray mold, tomato bacterial angular spot disease, etc.), grape diseases (such as: Grape downy mildew, grape gray mold, grape powdery mildew), apple disease (such as apple ring disease, apple anthracnose, etc.), citrus disease (citrus canker disease, citrus canker, citrus anthracnose), tobacco disease (tobacco Wildfire disease).
  • the other characteristics exhibited by the bactericidal composition of the present invention are mainly as follows: 1.
  • the compounding of the composition of the present invention has obvious synergistic effect; 2. Since the chemical composition of the two single agents of the present composition is greatly different, the effect The mechanism is completely different, There is no cross-resistance, which can delay the resistance problem caused by the two single agents being used alone; 3.
  • the composition of the invention is safe and effective against crops. It has been proved by experiments that the bactericidal composition of the invention has stable chemical properties, remarkable synergistic effect, and exhibits obvious synergistic effect and complementary effect on the control object.
  • the active ingredient active group A and the active component B, and the auxiliary agent and the filler are uniformly mixed according to the formula, and are pulverized into a wettable powder by a jet stream, and then added with a certain amount of water to be mixed and extruded, granulated, and dried and sieved.
  • a water dispersible granule product A water dispersible granule product.
  • Example 1 10% BIT ⁇ Amipyrene sulfonate water-dispersible granules (1:1)
  • Example 2 22% BIT ⁇ Ethylpyrene Water Dispersible Granules (1:10)
  • BIT 2% acetaminophen 20%, methyl naphthalene sulfonate formaldehyde condensate 6%, naphthalene sulfonate potassium 8%, fatty alcohol ammonium sulfate 6%, diatomaceous earth to 100%.
  • Example 3 10% MBIT ⁇ acetonitrile sulfonate water dispersible granules
  • MBIT was 5%, acetonitrile sulfonate 5%, and the remaining components were prepared in accordance with the procedure of Example 1.
  • Example 4 22% MBIT ⁇ ethylpyrrolidine water dispersible granules
  • Example 5 10% BBIT ⁇ acetaminophen sulfonate water dispersible granules
  • Example 6 22% BBIT ⁇ ethylpyrrolidine water dispersible granules
  • the active ingredient active group A and the active component B, and the components such as a dispersing agent, a wetting agent, a thickener and water are uniformly mixed according to the formula, and after being sanded and/or sheared at a high speed, a semi-finished product is obtained. After the analysis, the water is mixed and evenly filtered to obtain the finished product.
  • Example 8 52% BIT ⁇ acetaminophen sulfonate suspension (1:25)
  • BIT 2% acetaminophen sulfonate 50%, calcite 8%, ethylene glycol 4%, potassium lignin sulfonate 8%, methyl naphthalene sulfonate sodium formaldehyde condensate 5%, water to 100%.
  • Example 10 52% MBIT ⁇ acetaminophen sulfonate suspension
  • Example 12 52% BBIT ⁇ acetaminophen sulfonate suspension
  • the active ingredient A and the B active ingredient are sufficiently mixed with various auxiliary agents and fillers, and are pulverized by an ultrafine pulverizer to obtain a wettable powder.
  • Example 13 18% BIT ⁇ Ethylpyrene wettable powder (1:5)
  • Example 14 32% BIT ⁇ acetonitrile sulfonate wettable powder (1:15)
  • Example 15 46.5% BIT ⁇ Ethylpyrene wettable powder (1:30)
  • Example 16 18% MBIT ⁇ acetaminophen wettable powder
  • MBIT was 3%
  • acetaminophen was 15%
  • the remaining components were prepared in the same manner as in Example 13.
  • Example 17 32% MBIT ⁇ acetonitrile sulfonate wettable powder
  • Example 18 46.5% MBIT ⁇ acetaminophen wettable powder
  • Example 19 18% BBIT ⁇ acetaminophen wettable powder
  • Example 20 32% BBIT ⁇ acetaminophen sulfonate wettable powder
  • Example 21 46.5% BBIT ⁇ acetaminophen wettable powder
  • the control effect is converted into the probability value (y), the liquid height ( ⁇ g/ml) is converted into a logarithmic value (x), the virulence equation is calculated by the least squares method, and the neutral concentration EC50 is suppressed, and the virulence of the drug is calculated according to the method of Sun Yunpei. Exponential Co-toxicity Factor (CTC).
  • CTC Exponential Co-toxicity Factor
  • Measured virulence index (ATI) (standard drug EC50 / test drug EC50) * 100
  • Theoretical virulence index (TTI) A virulence index * Percentage of A in the mixture + B virulence index * Percentage of B in the mixture
  • CTC Co-toxicity coefficient [mixture measured virulence index (ATI) / mixed theory virulence index (TTI)] * 100
  • CTC ⁇ 80 the composition showed antagonism, 80 ⁇ CTC ⁇ 120, the composition showed an additive effect, CTC ⁇ 120, and the composition showed synergistic effect.
  • Test method In the early stage of the disease, the first spray was immediately performed, and after 7 days, the second application was carried out, each treatment of 4 cells, 20 square meters per cell. The incidence of the disease was investigated before the drug and 11 days after the second drug. Each plot was randomly sampled at 5 points, and 5 crops were investigated at each point. The percentage of the lesion area per leaf on the whole plant was counted and graded. Disease index and control effect.
  • Grade 1 less than 5 leaf lesions, less than 1 cm in length;
  • Grade 3 6-10 leaf lesions, some lesions are longer than 1 cm;
  • Grade 5 11-25 leaf lesions, some lesions are connected into pieces, and the lesion area accounts for 10-25% of the leaf area;
  • Grade 7 more than 26 leaf lesions, the lesions are connected into pieces, and the lesion area accounts for 26-50% of the leaf area;
  • Grade 9 The lesions are connected into pieces, and the area of the lesions accounts for more than 50% of the leaf area or the whole leaves are dead.
  • Table 7 Combination of BIT with acetem and its derivatives to control the control of wheat powdery mildew

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention concerne une composition fongicide comprenant deux principes actifs A et B. Le principe actif A est un composé ayant une structure représentée par la formule (I); le principe actif B est un éthirimol ou un dérivé de celui-ci; le rapport de poids entre les deux principes est de 1:1-30. L'invention concerne également un procédé de préparation de la composition et son utilisation. Les résultats de tests indiquent que la composition fongicide présente un effet synergique évident, et de surcroît, des quantités d'administration réduites et des coûts d'utilisation réduits. La composition fongicide est susceptible de prévenir et de traiter efficacement des maladies bactériennes ou fongiques particulières des cultures. Le mélange de fongicides avec différents mécanismes d'action et approches d'action a de bons effets pour élargir le spectre des champignons, réduire la résistance fongique et bactérienne, améliorer les effets de prévention et de traitement, etc..
PCT/CN2017/093018 2016-08-24 2017-07-14 Composition fongicide Ceased WO2018036302A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201610718278.1A CN106342826A (zh) 2016-08-24 2016-08-24 一种杀菌剂组合物
CN201610718278.1 2016-08-24

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WO2018036302A1 true WO2018036302A1 (fr) 2018-03-01

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WO (1) WO2018036302A1 (fr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106342826A (zh) * 2016-08-24 2017-01-25 江苏辉丰农化股份有限公司 一种杀菌剂组合物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1566104A (zh) * 1998-06-10 2005-01-19 拜尔公司 防治植物有害生物的组合物
CN1566113A (zh) * 1998-06-17 2005-01-19 拜尔公司 防治植物害虫的组合物
CN106342826A (zh) * 2016-08-24 2017-01-25 江苏辉丰农化股份有限公司 一种杀菌剂组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101669486B (zh) * 2009-10-16 2012-06-06 深圳诺普信农化股份有限公司 一种含苯醚菌酯的杀菌组合物
CN101984809B (zh) * 2010-07-22 2012-11-21 福建诺德生物科技有限责任公司 一种以松脂基植物油为载体的油悬制剂及其制备方法
CN102172240B (zh) * 2011-03-01 2015-09-30 陕西西大华特科技实业有限公司 一种含有噻霉酮和甲氧基丙烯酸酯类杀菌剂的杀菌组合物
CN103704234B (zh) * 2014-01-07 2015-04-01 中国农业科学院植物保护研究所 一种防治农业细菌性病害的组合物
CN105685061A (zh) * 2016-02-29 2016-06-22 陕西西大华特科技实业有限公司 噻霉酮在防治马铃薯种传病害及促根发芽上的应用

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1566104A (zh) * 1998-06-10 2005-01-19 拜尔公司 防治植物有害生物的组合物
CN1566113A (zh) * 1998-06-17 2005-01-19 拜尔公司 防治植物害虫的组合物
CN106342826A (zh) * 2016-08-24 2017-01-25 江苏辉丰农化股份有限公司 一种杀菌剂组合物

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