WO2018077311A1 - Composition for relieving eye strain and preparation method therefor - Google Patents

Abstract

Disclosed is a composition for relieving eye strain, said composition comprising the following components in parts by weight: 50-100 parts of vitamin C sodium, 10-20 parts of taurine, 10-20 parts of zinc gluconate, and 10-20 parts of a scented tea fruit extract. The present invention targets problems such as existing vitamin C-containing effervescent tablets having high acidity after dissolving, irritating the mouth, throat, oesophagus and gastric mucosa, being unsuitable for long-term use, losing efficacy during storage due to the vitamin C oxidizing easily, and being susceptible to moisture absorption. The composition has effects such as improving immunity, reducing blood sugar, blood pressure and blood lipids, clearing heat, improving eyesight, whitening and beautifying, and significantly improves symptoms such as blurred vision, dry eyes, swollen eyes, eye pain and photophobia.

Description

Composition for relieving visual fatigue and preparation method thereof Technical field

The invention belongs to the field of medicines, health foods and foods, and relates to a composition preparation and a preparation method thereof, in particular to a composition for relieving visual fatigue and a preparation method thereof.

Background technique

With the rapid development of modern technology and the popularity of the Internet, the use of computers has become more and more common. The number of Internet users in China has reached 710 million, and the Internet penetration rate has reached 51.7%. With the continuous improvement of the mobile communication network environment and the further popularization of smartphones, mobile Internet applications have penetrated into the lives of Internet users, and the use rate of mobile Internet access has also increased. At present, the number of mobile Internet users in China has reached 656 million. Computer and mobile phone radiation are causing more and more damage to the eyes, and more and more patients are suffering from eye diseases. The number of myopia in China is as high as 450 million. The prevalence of myopia in young people has ranked first in the world. With the increase of age, cataracts and glaucoma in middle-aged and old people The prevalence of various types of eye diseases is also increasing year by year. In order to improve the visual blur, dry eyes, eye swelling, eye pain, photophobia and other symptoms caused by the use of computers and mobile phones in daily life, thereby reducing the incidence of eye diseases, there have been a large number of products in the market to alleviate visual fatigue. The main ingredients are taurine, lutein, vitamins and other chemical components, and the effect is relatively simple.

Vitamin C is a commonly used drug or nutritional supplement in the clinic. It is one of the antioxidant vitamins. It is involved in the hydroxylation reaction in the body and is necessary for the formation of bone, tooth, connective tissue and non-epithelial cells. The normal function of bones and blood vessels, increase the resistance to disease, and is one of the essential nutrients for the human body. It is widely used in the prevention and treatment of various diseases. Vitamin C sodium is the sodium salt of vitamin C. The pH of the aqueous solution is close to neutral. It has the same effect as vitamin C, but because it is sodium salt, the performance is more stable. At the same time, there is no longer strong acidity of vitamin C. The drug is taken at the same time, which is better than vitamin C.

Effervescent tablets are a novel tablet developed and applied abroad in recent years. The difference between it and ordinary tablets is that it also contains an effervescent disintegrant. When the effervescent tablet is placed in drinking water, under the action of the effervescent disintegrant, a large amount of air bubbles are generated immediately, so that the tablet is quickly formed. Disintegration and melting, sometimes the bubbles generated by disintegration also cause the tablets to roll up and down in the water, accelerating their disintegration and melting. The gas generated when the tablet disintegrates is partially dissolved in the drinking water, so that the drinking water has a soda-like beauty when it is drunk in the mouth. Effervescent tablets have the following advantages: easy to store and carry; rapid disintegration, convenient taking, rapid onset; high bioavailability, can improve clinical efficacy; especially suitable for children, the elderly and patients who have difficulty swallowing pills; Effervescent tablets after seasoning, taste better, good medicine is not It is hard to make consumers or patients more willing to accept.

Summary of the invention

The invention has the advantages of relatively simple action for relieving visual fatigue products and high acidity after dissolution of vitamin C-containing effervescent tablets, great stimulation to oral cavity, throat esophagus and gastric mucosa, unsuitable for long-term administration, and easy to oxidize vitamin C during storage. The effervescent tablet is easy to absorb moisture and damp, and provides a composition for relieving visual fatigue and improving immunity, lowering blood sugar, blood pressure, blood fat, clearing heat, eyesight, whitening and beauty, and a preparation method thereof, and solving the product on the market. The effect is relatively simple, and the clinical application of vitamin C is unstable in quality and difficult to take for a long time. The composition for relieving visual fatigue of the invention has the advantages of safe, non-toxic side effects, and can be used for improving symptoms such as blurred vision, dry eyes, eye swelling, eye pain and photophobia for a long time; or long-term use as a nutritional supplement.

In order to solve the above technical problems, the present invention is achieved by the following technical solutions:

A composition for relieving visual fatigue, comprising the following components by weight: 50-100 parts of vitamin C sodium, 10-20 parts of taurine, 10-20 parts of zinc gluconate, and 10-20 parts of flower tea fruit extract.

The extract of the flower tea fruit described above is prepared from the following raw materials by weight: 40-60 parts of medlar flower, 20-40 parts of golden flower tea, and 5-10 parts of fresh lemon.

The preparation method of the above-mentioned flower tea fruit extract is as follows:

S1: Weigh the raw materials according to the following parts by weight: 40-60 parts of dense flower, 20-40 parts of golden flower tea, 5-10 parts of fresh lemon;

S2: Take the weighed Mengmenghua, Jinhuacha, add 6-10 times of water, soak for 30 minutes, extract 2-3 times, each time 30-40 minutes, filter, get the tea extract;

S3: Take a fresh lemon weighing, wash, peel, extract the original juice, filter, and obtain lemon juice;

S4: mixing the flower tea extract with lemon juice, and concentrating under reduced pressure at 80 ° C or lower to obtain a flow extract having a relative density of 1.18-1.22 at 60 ° C, drying the flow extract, and controlling the drying temperature to 65-80 ° C. Flower tea fruit extract.

The extraction method under the step S2 is preferably heated reflux extraction and ultrasonic extraction.

The drying method under the step S4 is preferably oven heating drying and spray drying.

The composition for relieving visual fatigue as described above preferably further comprises the following components by weight: 50-100 parts of tartaric acid, 60-150 parts of sodium hydrogencarbonate, and 20-40 parts of aspartame.

The above composition for relieving visual fatigue further preferably further comprises 0.5 to 1.0% of trehalose and 0.3 to 0.5% of lactose based on the total weight of the above components.

The above-mentioned composition for relieving visual fatigue preferably comprises the following components by weight: 80 parts of vitamin C sodium, 15 parts of taurine, 15 parts of zinc gluconate, 15 parts of flower tea fruit extract, 70 parts of tartaric acid. There are 100 parts of sodium hydrogencarbonate and 30 parts of aspartame, and further comprises trehalose in an amount of 0.8% by weight based on the total weight of the above components and lactose in an amount of 0.4% by weight based on the total weight of the above components.

The above-mentioned flower tea fruit extract is preferably preferably made of the following raw materials by weight: 50 parts of medlar, 30 parts of golden tea, and 8 parts of fresh lemon.

The preparation method of the composition for relieving visual fatigue mentioned above comprises the following steps:

T1: Preparation of flower tea fruit extract: Weigh the following raw materials by weight: 40-60 parts of dense flower, 20-40 parts of golden flower tea, 5-10 parts of fresh lemon; take densely weighed flower, golden flower tea Add 6-10 times of water, soak for 30 minutes, extract 2-3 times, each time 30-40 minutes, filter, get the tea fruit extract; take the fresh lemon, wash, peel, squeeze The juice is filtered, and the lemon juice is obtained; the flower tea extract is mixed with the lemon juice, and concentrated under reduced pressure at 80 ° C or lower to obtain a flow extract having a relative density of 1.18-1.22 at 60 ° C, and the flow extract is dried to control drying. The temperature is 65-80 ° C, and the tea fruit extract is obtained;

T2: Weigh the following components by weight: 50-100 parts of vitamin C sodium, 10-20 parts of taurine, 10-20 parts of zinc gluconate, 10-20 parts of flower tea fruit extract, 50-100 parts of tartaric acid, 60-150 parts of sodium hydrogencarbonate, 20-40 parts of aspartame; further weigh 0.5-1.0% of the total weight of the component of trehalose and 0.3-0.5% of the total weight of the component;

T3: Take 1/2 of the total weight of tartaric acid, flower tea fruit extract, 1/2 of the total weight of trehalose, aspartame, mix, spray 50-60% ethanol solution, mix, granulate, sieve , dry, whole grain, acidifier;

T4: Take 1/2 of the total weight of sodium bicarbonate and flower tea extract, 1/2 of the total weight of trehalose, mix, spray 50-60% ethanol solution, mix, granulate, sieve, dry, Whole grain, alkali agent;

T5: Take vitamin C sodium, taurine, zinc gluconate, acid, alkali, lactose, mix, tablet, that is.

The drying temperature in the step T3, T4 is preferably 80 ° C or less, so that the obtained particles have a moderate hardness, which is more favorable for tableting, and utilizes disintegration; and the screening step described in the steps T3 and T4 is used. The screen is preferably 14-30 mesh.

The beneficial effects of the invention are:

1. The invention overcomes the problem that the existing vitamin C-containing effervescent tablet has high acidity after dissolution, is irritating to the oral cavity, throat esophagus and gastric mucosa, and is not suitable for long-term use, and the vitamin C is easily oxidized and failed during storage, and the effervescent tablet It is easy to absorb moisture and damp, so that the product has better stability and more effective curative effect. It is suitable for long-term use by consumers or patients without side effects.

2. The raw materials of the tea fruit extract of the present invention are all "medicine and food homologous" varieties, wherein the dense Mongolian flower has the effects of hurricane, cooling blood, moistening the liver and improving eyesight, and is used for treating redness and swelling of the eye. More tears and shame, blue-blind dysfunction, windy string and eye, special medicine for ophthalmology; Golden Camellia is a plant with high medicinal value and high health value. It is unique to Guangxi, non-toxic and contains more than 400 kinds of nutrients. Studies have shown that Jinhuacha has obvious effects on regulating human blood lipids, blood sugar, cholesterol and enhancing immunity. It has been used in the public to refresh the brain, clear the liver fire, relieve heat and nourish the vital energy; fresh lemon has whitening skin care, It has the effects of improving heat, reducing blood sugar, blood pressure, blood fat, clearing heat, eyesight, whitening and beauty, and further strengthening its vision to improve vision and dry eyes. The effects of eye swelling, eye pain, photophobia and other symptoms have overcome the problem of mitigating the components and effects of visual fatigue products on the market.

3. The composition for relieving visual fatigue of the invention has the advantages of simple preparation, good fluidity of the particles, no sticking of the tablet, and the prepared tablet has a smooth surface, is not easy to absorb moisture, has uniform effervescent gas, and has short disintegration time and disintegration. After the solution is transparent and clear, the taste is sweet, the quality is stable, and the carrying is convenient. It has the characteristics of solid preparation and liquid preparation, and is especially suitable for children, the elderly and patients who cannot swallow solid preparations, has high bioavailability and is safer and more effective to use. Can be taken as a nutritional supplement for a long time.

detailed description

While the specification concludes with particular reference to the claims of the invention, it is believed that

As used herein, the word "preferred" and variants refers to embodiments of the invention that are capable of providing a particular benefit in a particular environment. However, other embodiments may be preferred under the same or other circumstances. In addition, the detailed description of one or more preferred embodiments does not indicate that other embodiments are useless and are not intended to exclude other embodiments from the scope of the invention.

First, the screening of preparation conditions

1. Selection of acid source and alkali source

The acid sources commonly used in effervescent tablets are tartaric acid, citric acid, fumaric acid, adipic acid, malic acid, etc.; alkali sources include sodium hydrogencarbonate, potassium carbonate, potassium hydrogencarbonate, calcium carbonate and the like. The effervescent tablet prepared by using sodium hydrogencarbonate as an alkali source can rapidly disintegrate in water, and the pH of the effervescent solution is suitable for the stabilization of vitamin C sodium, so the alkali source of the present invention selects sodium hydrogencarbonate. On the basis of the fixed alkali source being sodium bicarbonate, the formulation in Table 1 is followed by tartaric acid, Citric acid, fumaric acid, malic acid, and adipic acid were selected to determine the best source of acid in the effervescent tablet.

Table 1 Preferred test of acid source and alkali source

It can be seen from the test results in Table 1 that the present invention uses tartaric acid mixed with vitamin C sodium, sodium hydrogencarbonate and aspartame, and is good for granulation, the lapse of disintegration time is short, the solution is clear, the mouthfeel is good, but it is sticky when tableting. The rushing phenomenon is better than other acid sources, so the acid source of the present invention selects tartaric acid, and the alkali source selects sodium hydrogencarbonate.

2. Adhesive selection

The invention compares the dry pressing tablet, the wet granulation and the re-pulling, the dry pressing tablet adopts the ordinary tableting machine has a poor effect and has high requirements on the equipment, so the invention adopts the wet granulation and the tableting. In the test, 30% starch slurry, 40% sucrose syrup, 5% hypromellose aqueous solution, and 55% ethanol were used as binders. The results are shown in Table 2.

Table 2 Adhesive inspection results table

It can be seen from the test results in Table 2 that the granulation effect and the effervescence effect of the present invention using 55% ethanol are the best, so that the binder of the present invention selects 55% ethanol. In order to further optimize the ethanol concentration, the present invention continues to optimize the ethanol concentration, and the test results are shown in Table 3.

Table 3 Table of results of ethanol concentration

It can be seen from the test results in Table 3 that the present invention uses 50%-60% ethanol to granulate and has good effervescence effect, the concentration is too low, and the concentration is too high, which affects the effervescence time, so the adhesive of the present invention selects 50%. -60% ethanol.

3. Selection of stabilizers

Vitamin C sodium is the sodium salt of vitamin C. Its performance is more stable than vitamin C, but it is prepared into effervescent tablets. In the acid, alkali, other auxiliary materials and the influence of moisture and oxidation in the air, it is necessary to guarantee the product during the shelf life. The quality is stable and it is still necessary to add stabilizers. In the test, 0.02% EDTA disodium, 1% trehalose, and 0.2% sodium sulfite were compared. The samples prepared by the above stabilizers were respectively packaged with aluminum-plastic composite film, and the stability was accelerated in the test chamber: temperature: 40±2°C, relative humidity: 75±5%, accelerated test for 3 months, the test results are shown in Table 4.

Table 4 Stabilizer test results table

From the test results in Table 4, it is known that using EDTA disodium and sodium sulfite as stabilizers, the water content changes. Larger, it is easy to cause internal reaction of the acid agent alkali agent, the pH of the solution is lowered and the oxidation is accelerated, resulting in a decrease in the vitamin C sodium content. With 1% trehalose as a stabilizer, after the accelerated test, the moisture does not change much, and the appearance, effervescence reaction time, solution pH and vitamin C sodium content change little, so the present invention uses 1% trehalose as a stabilizer, for which, The amount of trehalose added was further investigated and the obtained sample was subjected to an accelerated test. The test method was the same as in Table 4, and the results are shown in Table 5.

Table 5 Test results of the amount of trehalose added

From the test results in Table 5, the moisture, appearance, and bubble of the effervescent tablet after adding 0.2-0.4% trehalose The reaction time, solution pH and vitamin C sodium content were all changed greatly; while the physical and chemical indicators of effervescent tablets containing 0.5-1.0% trehalose changed little during the acceleration period of 3 months, and the quality was stable; 1.2-1.5 The appearance, pH value and content index of the % trehalose effervescent tablet did not change much during the acceleration period of 3 months, and the quality remained stable during the acceleration period of 3 months, but the change of water and effervescence reaction time exceeded the quality standard. Therefore, the amount of trehalose controlled by the present invention is 0.5-1.0%.

4. Selection of lubricants

The material before the tableting of the invention has acid agent, sodium vitamin C, sweetener and alkali agent, and the particle size and texture of the material are uneven. When the tablet is pressed, the particle flowability is poor, and the tablet is easy to stick and punch. In the test of the present invention, the formulas except the lubricant are the same, and after the preliminary test is used to determine the available ratio, the different amounts of the dodecyl magnesium sulfate, lactose, mannitol, and the samples prepared by using the above lubricants are specifically compared. They are packaged with aluminum-plastic composite film respectively, and the stability test is accelerated in the test chamber: temperature: 40±2°C, relative humidity: 75±5%, accelerated test for 3 months, and the results are shown in Table 6.

Table 6 Lubricant Trial Results Table

From the test results in Table 6, it is known that the fluidity of adding 0.3-0.5% of lactose is good, and the tableting is not sticky. The one-sided surface is smooth and beautiful, but the accelerated test found that the addition of lactose increased, the water content increased, and the effervescence reaction time also increased a lot, which did not meet the eluate disintegration time requirement. Therefore, 0.3-0.5% of lactose was selected as the lubricant in the present invention.

Second, a method for preparing a composition for relieving visual fatigue

Example 1

A method for preparing a composition for relieving visual fatigue, comprising the steps of:

T1: Preparation of flower tea fruit extract: Weigh the following raw materials by weight: 40 parts of densely scented flowers, 40 parts of golden scented tea, and 5 parts of fresh lemon; take a good amount of densely scented flowers, golden scented tea, and add 6 times of water Soak for 30 minutes, heat and reflux for 3 times, each time for 30 minutes, filter, get the tea extract; take the fresh lemon, wash, peel, extract the juice, filter, get lemon juice; The flower tea extract is mixed with lemon juice, concentrated under reduced pressure at 80 ° C or lower, and a flow extract having a relative density of 1.20 at 60 ° C is obtained, and the flow extract is spray-dried to control the drying temperature to 70 ° C to obtain a flower tea fruit extract;

T2: Weigh the following components by weight: 50 parts of vitamin C sodium, 10 parts of taurine, 10 parts of zinc gluconate, 10 parts of flower tea fruit extract, 50 parts of tartaric acid, 60 parts of sodium hydrogencarbonate, aspartame 20 parts; further weigh 0.5% of the total weight of the components of trehalose and 0.3% of the total weight of the components of lactose;

T3: Take 1/2 of the total weight of tartaric acid, flower tea fruit extract, 1/2 of the total weight of trehalose, aspartame, mix, spray 50% ethanol solution, mix, granulate, pass 20 mesh sieve Dry at 80 ° C, whole grain, acidifier;

T4: Take 1/2 of the total weight of sodium bicarbonate and flower tea extract, 1/2 of the total weight of trehalose, mix, spray 50% ethanol solution, mix, granulate, pass 20 mesh sieve, 80 ° C Drying, granules, alkali agent;

T5: Take vitamin C sodium, taurine, zinc gluconate, acid, alkali, lactose, mix, tablet, that is.

Example 2

A method for preparing a composition for relieving visual fatigue, comprising the steps of:

T1: Preparation of flower tea fruit extract: Weigh the following raw materials by weight: 50 parts of densely scented flowers, 30 parts of golden scented tea, and 7 parts of fresh lemon; take a good amount of densely scented flowers, golden scented tea, and add 8 times of water Soak for 30 minutes, heat and reflux for 2 times, each time for 40 minutes, filter, get the tea extract; take the fresh lemon, wash, peel, squeeze the juice, filter, get lemon juice; The flower tea extract is mixed with lemon juice, concentrated under reduced pressure at 80 ° C or lower, and a flow extract having a relative density of 1.18 at 60 ° C is obtained, and the flow extract is spray-dried to control the drying temperature to 80 ° C to obtain a flower tea fruit extract;

T2: Weigh the following components by weight: 80 parts of vitamin C sodium, 15 parts of taurine, 15 parts of zinc gluconate, 15 parts of flower tea fruit extract, 70 parts of tartaric acid, 100 parts of sodium hydrogencarbonate, aspartame 30 parts; further weigh 0.8% of the total weight of the components of trehalose and 0.4% of the total weight of the components of lactose;

T3: Take 1/2 of the total weight of tartaric acid, flower tea fruit extract, 1/2 of the total weight of trehalose, aspartame, mix, spray 55% ethanol solution, mix, granulate, pass 30 mesh sieve Dry at 80 ° C, whole grain, acidifier;

T4: Take 1/2 of the total weight of sodium bicarbonate and flower tea extract, 1/2 of the total weight of trehalose, mix, spray 55% ethanol solution, mix, granulate, pass 30 mesh sieve, 80 ° C Drying, granules, alkali agent;

T5: Take vitamin C sodium, taurine, zinc gluconate, acid, alkali, lactose, mix, tablet, that is.

Example 3

A method for preparing a composition for relieving visual fatigue, comprising the steps of:

T1: Preparation of flower tea fruit extract: Weigh the following raw materials by weight: 60 parts of densely scented flowers, 40 parts of golden scented tea, and 10 parts of fresh lemon; take a good amount of medlar flower, golden flower tea, add 10 times of water Soak for 30 minutes, ultrasonic extraction 3 times, 40 minutes each time, filter, get the tea extract; take the fresh lemon, wash, peel, extract the juice, filter, get lemon juice; The extract is mixed with lemon juice, concentrated under reduced pressure at 80 ° C to obtain a flow extract having a relative density of 1.22 at 60 ° C, and the flow extract is placed in an oven for heating and drying, and the drying temperature is controlled to 65 ° C to obtain a tea fruit extract. ;

T2: Weigh the following components by weight: 100 parts of vitamin C sodium, 20 parts of taurine, 20 parts of zinc gluconate, 20 parts of flower tea fruit extract, 100 parts of tartaric acid, 150 parts of sodium hydrogencarbonate, aspartame 40 parts; further weigh 1.0% of the total weight of the component of trehalose and 0.5% of the total weight of the component of lactose;

T3: Take 1/2 of the total weight of tartaric acid, flower tea fruit extract, 1/2 of the total weight of trehalose, aspartame, mix, spray 60% ethanol solution, mix, granulate, pass 14 mesh sieve Dry at 80 ° C, whole grain, acidifier;

T4: Take 1/2 of the total weight of sodium bicarbonate and flower tea extract, 1/2 of the total weight of trehalose, mix, spray 60% ethanol solution, mix, granulate, pass 14 mesh sieve, 80 ° C Drying, granules, alkali agent;

T5: Take vitamin C sodium, taurine, zinc gluconate, acid, alkali, lactose, mix, tablet, that is.

Third, the stability test

The samples of the above Examples 1-3 were respectively packaged with an aluminum-plastic composite film, and the stability was accelerated in the test chamber: temperature: 40±2° C., relative humidity: 75±5%, accelerated test for 3 months, and the results were as follows. 1-3 samples of the appearance of the traits, moisture, effervescence reaction time, solution pH, the main component content and other stability key indicators compared with the 0-time sample measurement results, there is no significant change, indicating the examples 1-3 samples of the present invention The quality is relatively stable and can meet the stability requirements of storage, transportation and use. The test results are shown in Table 7.

Table 7 Table of results of stability test of effervescent tablets for relieving visual fatigue

Claims (12)

A composition for relieving visual fatigue, which comprises the following components by weight: 50-100 parts of vitamin C sodium, 10-20 parts of taurine, 10-20 parts of zinc gluconate, and extract of flower tea fruit 10 -20 servings; The camellia fruit extract is prepared from the following raw materials by weight: 40-60 parts of medlar, 20-40 parts of golden tea, and 5-10 parts of fresh lemon. The composition for relieving visual fatigue according to claim 1, wherein the method for preparing the teafruit extract is: S1: Weigh the raw materials according to the following parts by weight: 40-60 parts of dense flower, 20-40 parts of golden flower tea, 5-10 parts of fresh lemon; S2: Take the weighed Mengmenghua, Jinhuacha, add 6-10 times of water, soak for 30 minutes, extract 2-3 times, each time 30-40 minutes, filter, get the tea extract; S3: Take a fresh lemon weighing, wash, peel, extract the original juice, filter, and obtain lemon juice; S4: mixing the flower tea extract with the lemon juice, and concentrating under reduced pressure at 80 ° C or lower to obtain a flow extract having a relative density of 1.18-1.22 at 60 ° C, drying the flow extract, and controlling the drying temperature to be 65-80 ° C. Flower tea fruit extract. The composition for relieving visual fatigue according to claim 2, wherein the extraction method under step S2 is heated reflux extraction and ultrasonic extraction. The composition for relieving visual fatigue according to claim 2, wherein the drying method in the step S4 is oven heating drying and spray drying. The composition for relieving visual fatigue according to any of claims 2 to 4, wherein the auxiliary material is formulated into a health food or a food-allowed preparation. The composition for relieving visual fatigue according to claim 5, wherein the preparation is a granule, a pill, a tablet, a capsule, an oral liquid, a syrup, a drink or a tea. The composition for relieving visual fatigue according to claim 6, wherein the tablet is an effervescent tablet. The composition for relieving visual fatigue according to claim 7 is prepared as an effervescent tablet, which further comprises the following components by weight: 50-100 parts of tartaric acid, 60-150 parts of sodium hydrogencarbonate, Aspen Ba sweet 20-40 copies. The composition for relieving visual fatigue according to claim 8 which is prepared as an effervescent tablet, which further comprises 0.5 to 1.0% of trehalose based on the total weight of the above components and 0.3% by weight of the total weight of said components. -0.5% milk sugar. A method of preparing an effervescent tablet for a composition for relieving visual fatigue according to claim 9, comprising the steps of: T1: Preparation of flower tea fruit extract: Weigh the following raw materials by weight: 40-60 parts of dense flower, 20-40 parts of golden flower tea, 5-10 parts of fresh lemon; take densely weighed flower, golden flower tea Add 6-10 times of water, soak for 30 minutes, extract 2-3 times, each time 30-40 minutes, filter, get the tea extract; take the fresh lemon, wash, peel, squeeze the original Juice, filtered, and get lemon juice; mix the flower tea extract with lemon juice, concentrate under reduced pressure at 80 ° C or lower, obtain a flow extract with a relative density of 1.18-1.22 at 60 ° C, dry the extract, and control the drying temperature. 65-80 ° C, obtained flower tea fruit extract; T2: Weigh the following components by weight: 50-100 parts of vitamin C sodium, 10-20 parts of taurine, 10-20 parts of zinc gluconate, 10-20 parts of flower tea fruit extract, 50-100 parts of tartaric acid, 60-150 parts of sodium hydrogencarbonate, 20-40 parts of aspartame; further weigh 0.5-1.0% of the total weight of the component of trehalose and 0.3-0.5% of the total weight of the component; T3: Take 1/2 of the total weight of tartaric acid, flower tea fruit extract, 1/2 of the total weight of trehalose, aspartame, mix, spray 50-60% ethanol solution, mix, granulate, sieve , dry, whole grain, acidifier; T4: Take 1/2 of the total weight of sodium bicarbonate and flower tea extract, 1/2 of the total weight of trehalose, mix, spray 50-60% ethanol solution, mix, granulate, sieve, dry, Whole grain, alkali agent; T5: Take vitamin C sodium, taurine, zinc gluconate, acid, alkali, lactose, mix, tablet, that is. A method of preparing an effervescent tablet for a composition for relieving visual fatigue according to claim 8, wherein the temperature for drying under steps T3 and T4 is 80 ° C or lower. A method of making an anti-fatigue composition according to claim 8 as an effervescent tablet, characterized in that the screen used in the sieving step described in steps T3, T4 is 14-30 mesh.