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WO2016184062A1 - Biocapteur basé sur un nanomatériau semi-conducteur sensible de manière photoélectrique - Google Patents

Biocapteur basé sur un nanomatériau semi-conducteur sensible de manière photoélectrique Download PDF

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Publication number
WO2016184062A1
WO2016184062A1 PCT/CN2015/095041 CN2015095041W WO2016184062A1 WO 2016184062 A1 WO2016184062 A1 WO 2016184062A1 CN 2015095041 W CN2015095041 W CN 2015095041W WO 2016184062 A1 WO2016184062 A1 WO 2016184062A1
Authority
WO
WIPO (PCT)
Prior art keywords
responsive semiconductor
cds
photoelectrically responsive
semiconductor nanomaterial
photoelectrically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2015/095041
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English (en)
Chinese (zh)
Inventor
周明
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NANTONG MINICHIP MICRO-ELECTRONICS Co Ltd
Original Assignee
NANTONG MINICHIP MICRO-ELECTRONICS Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NANTONG MINICHIP MICRO-ELECTRONICS Co Ltd filed Critical NANTONG MINICHIP MICRO-ELECTRONICS Co Ltd
Publication of WO2016184062A1 publication Critical patent/WO2016184062A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

Definitions

  • the invention relates to a biosensor based on photoelectric responsive semiconductor nano material, and belongs to the technical field of materials.
  • a biosensor is an instrument that is sensitive to biological substances and converts its concentration into electrical signals for detection. It is made up of immobilized bio-sensitive materials as identification elements (including enzymes, antibodies, antigens, microorganisms, cells, tissues, nucleic acids and other biologically active substances), appropriate physical and chemical transducers (such as oxygen electrodes, photosensitive tubes, FETs, An analytical tool or system consisting of a piezoelectric crystal or the like and a signal amplifying device. Biosensors have the function of a receiver and a converter.
  • the biosensor based on the photoelectric responsive semiconductor nanomaterial of the present invention comprises a molecular recognition portion and a conversion portion, wherein the molecular recognition portion is selected from a photoelectrically responsive semiconductor nano material, and the photoelectric responsive semiconductor nano material is prepared by the following method. :
  • the surfactant is polyethylene glycol.
  • the biosensor based on the photoelectric responsive semiconductor nano material of the invention has high sensitivity and good selectivity.
  • the biosensor based on the photoelectric responsive semiconductor nanomaterial of the present invention comprises a molecular recognition portion and a conversion portion, wherein the molecular recognition portion is selected from a photoelectrically responsive semiconductor nano material, and the photoelectric responsive semiconductor nano material is prepared by the following method. :
  • the surfactant is polyethylene glycol.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Silicon Compounds (AREA)
  • Light Receiving Elements (AREA)

Abstract

L'invention concerne un biocapteur basé sur un nanomatériau semi-conducteur sensible de manière photoélectrique. Le biocapteur comprend une partie d'identification de molécule et une partie de transducteur. Un nanomatériau semi-conducteur sensible de manière photoélectrique est sélectionné pour la partie d'identification de molécule et est préparé selon le procédé suivant : 1) préparer un cristal de silice à partir de silice colloïdale, et obtenir des nanotiges sur une surface d'une pièce d'or par évaporation par faisceau d'électrons ; 2) préparer des particules de CdS à l'aide d'un procédé hydrothermal, et réaliser un traitement de modification de surface sur les nanoparticules de CdS avec un tensioactif ; et 3) adsorber les nanoparticules de CdS sur les surfaces des nanotiges pour obtenir le nanomatériau semi-conducteur sensible de manière photoélectrique en SiO2-CdS. Le biocapteur basé sur un nanomatériau semi-conducteur sensible de manière photoélectrique a une sensibilité élevée et une bonne sélectivité.
PCT/CN2015/095041 2015-05-15 2015-11-19 Biocapteur basé sur un nanomatériau semi-conducteur sensible de manière photoélectrique Ceased WO2016184062A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201510245581.X 2015-05-15
CN201510245581.XA CN104965067A (zh) 2015-05-15 2015-05-15 基于光电响应性半导体纳米材料的生物传感器

Publications (1)

Publication Number Publication Date
WO2016184062A1 true WO2016184062A1 (fr) 2016-11-24

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PCT/CN2015/095041 Ceased WO2016184062A1 (fr) 2015-05-15 2015-11-19 Biocapteur basé sur un nanomatériau semi-conducteur sensible de manière photoélectrique

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CN (1) CN104965067A (fr)
WO (1) WO2016184062A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104965067A (zh) * 2015-05-15 2015-10-07 南通明芯微电子有限公司 基于光电响应性半导体纳米材料的生物传感器

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WO2013064885A1 (fr) * 2011-11-01 2013-05-10 Bigtec Private Limited Procédé de détection et/ou d'isolement d'une biomolécule faisant appel à des nanostructures
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WO2006116683A1 (fr) * 2005-04-27 2006-11-02 The Trustees Of The University Of Pennsylvania Nanostructure a luminescence amelioree
CN101191794A (zh) * 2007-08-27 2008-06-04 中国科学院理化技术研究所 一维纳米结构的荧光化学生物传感器及其制备方法和用途
CN101629076A (zh) * 2008-07-16 2010-01-20 北京大学 二氧化硅包被的荧光量子点纳米颗粒及其制备方法
CN101906298A (zh) * 2010-08-13 2010-12-08 济南大学 一种含有表面等离子体荧光增强的纳米复合结构的薄膜及其制备方法
WO2013042012A1 (fr) * 2011-09-19 2013-03-28 Bar-Ilan Research And Development Company Ltd. Conjugaison coeur-écorce d'un nanotube de silice et de polythiophène utile dans une microbalance à cristal de quartz (qcm), et procédé de fabrication correspondant
WO2013064885A1 (fr) * 2011-11-01 2013-05-10 Bigtec Private Limited Procédé de détection et/ou d'isolement d'une biomolécule faisant appel à des nanostructures
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CN103241766A (zh) * 2013-05-07 2013-08-14 常州大学 SiO2纳米棒/CdS的制备方法
CN104965067A (zh) * 2015-05-15 2015-10-07 南通明芯微电子有限公司 基于光电响应性半导体纳米材料的生物传感器

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