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WO2016013228A1 - Composition de réduction d'aldéhyde - Google Patents

Composition de réduction d'aldéhyde Download PDF

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Publication number
WO2016013228A1
WO2016013228A1 PCT/JP2015/003713 JP2015003713W WO2016013228A1 WO 2016013228 A1 WO2016013228 A1 WO 2016013228A1 JP 2015003713 W JP2015003713 W JP 2015003713W WO 2016013228 A1 WO2016013228 A1 WO 2016013228A1
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Prior art keywords
extract
gum
jasmine tea
tea extract
composition
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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PCT/JP2015/003713
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English (en)
Japanese (ja)
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WO2016013228A9 (fr
Inventor
範 菅野
正典 小柳津
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lotte Co Ltd
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Lotte Co Ltd
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Priority to KR1020177004535A priority Critical patent/KR20170038842A/ko
Priority to CN201580041150.XA priority patent/CN106573027A/zh
Publication of WO2016013228A1 publication Critical patent/WO2016013228A1/fr
Anticipated expiration legal-status Critical
Publication of WO2016013228A9 publication Critical patent/WO2016013228A9/fr
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/82—Theaceae (Tea family), e.g. camellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Definitions

  • An aldehyde-reducing composition is provided.
  • the aldehyde odor of breath after drinking can be removed. Used for the treatment of drunkenness.
  • Example 3 The result of Example 3 is shown.
  • the result of Example 4 is shown.
  • the present invention is at least one selected from jasmine tea extract, tomato powder, blueberry extract, cassis extract, epigallocatechin gallate, tea extract, loaf extract, grape seed extract, assam extract, and safflower extract.
  • An aldehyde-reducing composition characterized in that it contains one.
  • Jasmine tea is made by scenting the base tea leaves with the scent of jasmine flowers, removing the flowers after flavoring, drying and then flavoring again as needed.
  • the extracted jasmine tea is extracted with water or a polar organic solvent, sterilized and freeze-dried through a concentration step such as centrifugation and filtration, and then pulverized.
  • the method for extracting jasmine tea is not particularly limited.
  • an extraction solvent that can be used for extraction, water, polar organic solvents such as methanol, ethanol, 1-butanol, 2-propanol, and 1-propanol, and a mixture of these polar organic solvents and water can be preferably used.
  • water alone cold water or hot water
  • a mixture of water and ethanol hydrophilic ethanol
  • the extraction solvent may be added in an amount of 10 to 200 times, preferably 20 to 100 times, when the dry weight of jasmine tea is 1.
  • the extraction temperature is preferably 40 to 100 ° C, more preferably 70 to 100 ° C.
  • the heating time is 1 to 120 minutes, preferably 5 to 60 minutes.
  • composition of the present invention can reduce aldehyde in the oral cavity. Moreover, the composition of this invention can reduce the aldehyde in an oral cavity by being chewed.
  • the composition of this embodiment can be expected to have a sufficient deodorizing effect by gradually eluting the jasmine tea extract as it is chewed.
  • the content of the jasmine tea extract in the composition is not limited, but is preferably 0.1% to 10% by weight in the composition.
  • a preferred example of the composition is chewing gum.
  • the content of jasmine tea extract in the composition is preferably 1.0% to 10% by weight. This is because if the amount is less than 1.0% by weight, a sufficient aldehyde reduction effect cannot be obtained, while if it exceeds 10% by weight, the binding property is poor, and the shape becomes sober and cannot be molded.
  • the composition of the present invention can contain a liquid part.
  • the liquid part is a liquid part having an appropriate viscosity, and is intended to flow out into the oral cavity when the composition is encapsulated and the composition is chewed.
  • the content of jasmine tea extract in the liquid part is preferably 15% by weight or less per liquid part. This is because if the content ratio of the jasmine tea extract in the liquid part exceeds 15% by weight, the liquid part becomes too viscous and it may be difficult to fill the composition.
  • an immediate deodorizing effect can be obtained immediately after chewing the composition.
  • composition of the present invention are chewing gum, candy, tablet confectionery, beverage, gummy jelly, chocolate, biscuits, ice cream, sherbet, or a pharmaceutical composition for reducing acetaldehyde. , Breath breath sprays, toothpastes, troches, and pharmaceutical gums.
  • Example 1 Screening of substances having an acetaldehyde reducing effect.
  • the experiment was conducted as follows. That is, in a glass test tube (capacity 18 mL) that can be sealed, 1 mL of 0.2 M phosphate buffer (pH 7.5), 1 mL of water or sample solution (100 mg of each sample dissolved or dispersed in 1 mL of water), 0.5 mL of acetaldehyde 1/500 (v / v) solution was added, and after sealing and stirring, the solution was left in a 37 ° C. hot water bath for 10 minutes. Ten minutes later, 100 ⁇ L of test tube headspace gas was collected with a syringe, and the amount of acetaldehyde was analyzed by gas chromatography. The acetaldehyde elimination amount was calculated by comparison with water.
  • the amount of acetaldehyde in the headspace gas detected when 1 mL of 0.2 M phosphate buffer (pH 7.5), 1 mL of water, and 0.5 mL of acetaldehyde 1/500 (v / v) solution was added was 22.3 ⁇ g / tube (Table 1).
  • Table 2 shows the amount of elimination of acetaldehyde in the headspace gas by each substance.
  • the jasmine tea extract erased 3.0 ⁇ g / tube, or 13.3% by weight, of acetaldehyde in the headspace gas.
  • tomato powder (the amount of elimination of acetaldehyde in the headspace gas is 3.4 ⁇ g / tube, ie 15.2% by weight), blueberry extract (3.3 ⁇ g) as an ingredient that showed the same erasing ability as jasmine tea extract / Tube, ie 15.0% by weight), cassis extract (3.3 ⁇ g / tube, ie 15.0% by weight), EGCg high purity product (3.0 ⁇ g / tube, ie 13.4% by weight), tea extraction Product (2.9 ⁇ g / tube, ie 13.1% by weight), loaf extract (2.9 ⁇ g / tube, ie 12.9% by weight), grape seed extract (2.6 ⁇ g / tube, ie 11.7% by weight) %), Assam extract (2.1 ⁇ g / tube, ie 9.2 wt%), safflower extract (2.0 ⁇ g / tube, ie 9. There was a 9 material of weight%). Table 9 shows detailed experimental results for these nine materials.
  • tomato powder is a dried fruit powder using tomato pulp with a Brix value of 5.
  • the blueberry extract is an extract from blueberry fruits, and the total amount of anthocyanidins is 25.0% or more.
  • a cassis extract is an extract from a cassis (black currant) fruit, and the total amount of anthocyanins is 30.0% or more.
  • the EGCg high-purity product is an extract derived from green tea, and the EGCg content is 90.0% or more.
  • the tea extract is a tan powder, and the content of catechins is 30.0% or more.
  • the yoyohi extract is obtained by extracting with water-containing alcohol from the bark of yoyohi (bayberry).
  • the grape seed extract is an extract from grape seeds, and the proanthocyanidin content is 95.0% or more.
  • Assam extract is a hot water extraction using 100% Assam tea leaves.
  • the safflower extract is an extract derived from dried safflower.
  • the jasmine tea extract is as described above.
  • the numerical values in Table 2 indicate the acetaldehyde elimination amount ( ⁇ g / tube) in the headspace gas and the acetaldehyde elimination rate (% by weight).
  • Suitable as a reducing composition characterized by reducing the aldehyde in the oral cavity by chewing which is one of the embodiments of the present invention, from the above-mentioned nine types of acetaldehyde-reducing effects.
  • Selected material. Tomato powder and blueberry extract are not optimal as chewing compositions because of the strong taste peculiar to the material and limited flavor and variety. Tomato powder is highly hygroscopic and has a large effect on the physical properties of the composition.
  • Cassis extract, Assam extract, and safflower extract have strong astringency, and EGCg high-purity product and tea extract have particularly strong bitterness and astringency, and their flavor and variety are limited, so they are not optimal as chewing compositions.
  • jasmine tea extract When included in the composition, the yoihihi extract or grape seed extract gives a feeling of tooth tingling (such as teeth and gum rubbing) during chewing, and is therefore not optimal for use as a chewing composition.
  • jasmine tea extract is excellent as a chewing composition in terms of taste and fragrance, and also has good compatibility with mint flavor and menthol flavor. In addition, it is a fine powder compared to other plant extracts, and is an example of a chewing composition. When used in gum, it is excellent in terms of dispersibility in the gum and dispersibility in the liquid part. It was. For the above reasons, in the present invention, jasmine tea extract was selected as the optimum substance as the substance having an acetaldehyde reducing effect.
  • Example 2 As an example of the composition of the present invention, jasmine tea extract-containing liquid center gum 1, jasmine tea extract-containing liquid center gum 2 and a control liquid center gum were prepared. These liquid center gums consist of a gum part, a sugar coating part and a liquid part, and one gum is 2.5 grams. Each formulation is shown in Table 4.
  • the numerical values in Table 4 indicate the weight percentage of each raw material.
  • the prepared liquid center gums are each 2.5 grams / grain.
  • Example 3 Evaluation of acetaldehyde erasing effect of chewing saliva by using gum containing jasmine tea extract 10 mL of saliva was collected from a subject who chewed 2 tablets of jasmine tea extract-containing liquid center gum 1.
  • saliva of a subject who chewed Morita's salvary gum was also collected. The subject was instructed not to swallow any secreted saliva but to discharge it into the collection container. The chewing of the jasmine tea extract-containing liquid center gum 1 and the saliva gum was each continued until 10 mL of saliva was collected.
  • the results are shown in FIG.
  • the vertical axis of the graph in FIG. 1 indicates the amount of acetaldehyde when the amount of acetaldehyde in the headspace gas when the saliva of a subject chewing saliva gum is used is 100.
  • the amount of acetaldehyde in the headspace gas when using the saliva of a subject chewing the jasmine tea extract-containing liquid center gum 1 was 78.7, indicating that the amount of volatile acetaldehyde decreased by more than 20%. Further, a significant difference was detected as a result of the t test (p ⁇ 0.05).
  • Example 4 Evaluation of the effects of liquid center gum 1 containing jasmine tea extract on exhaled breath acetaldehyde from 1 drink each of liquid center gum 1 containing jasmine tea extract and control liquid center gum for 5 minutes in 5 mL water using a pestle and mortar Eluted and used as eluent.
  • Three male subjects (average 32.3 ⁇ 5.1 years old) ingested 500 mL of beer (Asahi Breweries Super Dry) at their own pace (within 15 minutes) and remained at rest for 30 minutes after drinking. After resting for 30 minutes, the smell bag (3 L) was put in the mouth for 1 minute, and the breath was collected in the smell bag at the pace of one's breath (exhalation before rinsing).
  • the mouth was rinsed with 5 mL of either of the two eluates described above for 1 minute, and similarly, the sachet was added to the mouth for 1 minute, and the breath was collected in the sachet at its own breathing pace (exhaled after rinsing). Thereafter, the mouth was rinsed with water, rested for 5 minutes, and the exhaled breath was collected before the second rinse.
  • Acetaldehyde was adsorbed on the fiber for 10 minutes from the odor bag by solid-phase microextraction (SPME, manufactured by SUPELCO). After adsorption, it was subjected to gas chromatography. Compared with before rinsing, the amount of acetaldehyde decreased was calculated. For subjects 2 and 3, the same experiment was performed again on the next day (second day) by changing the order of the rinses.
  • the amount of acetaldehyde decrease on day 1 and day 2 was 0.7 and 7.0 ppm (before rinsing: 163.7 ppm, 209.3 ppm ⁇ after rinsing: 163.0 ppm, respectively) in the control liquid center gum eluate. , 202.3 ppm) and 26.7, 36.5 ppm (before rinsing: 200.2 ppm, 220.5 ppm ⁇ after rinsing: 173.5 ppm, 184.0 ppm) in the liquid center gum 1 eluate containing jasmine tea extract It was.
  • control liquid center gum eluate and the liquid center gum 1 eluate containing jasmine tea extract were used in 3 subjects (subject 1 is the value of 1 time, and subjects 2 and 3 are the average value of 2 times). The amount of acetaldehyde decrease before and after rinsing was shown.
  • Example 5 Setting of blending amount of jasmine tea extract in jasmine tea extract-containing liquid center gum
  • jasmine tea extract-containing liquid center gum 1 and jasmine tea extract-containing liquid center gum 2 shown in Table 4 the total amount of gum
  • the amount of the jasmine tea extract in the mixture is 2.0% by weight and 3.2% by weight, respectively.
  • the compounding quantity of the jasmine tea extract in a liquid part is 2.1 weight% and 2.8 weight%, respectively. Both gums show an acetaldehyde deodorizing effect, and it has been found that there is no problem in the moldability of the gum.
  • the jasmine tea extract content in the liquid part is preferably 15% by weight or less per liquid part.
  • the blending of the liquid center gum 1 containing the jasmine tea extract shown in Table 4 is basically used.
  • the compounding quantity of the jasmine tea extract in a liquid part was set to 0. In addition, it adjusted so that the total weight of a gum part might become constant by decreasing the compounding quantity of erythritol by the part which increased the compounding of the jasmine tea extract.
  • the gum of (3) that is, the gum containing 4.0% by weight of jasmine tea extract in the total amount of gum
  • the gum of (4) that is, the gum containing 5.0% by weight of jasmine tea extract in the total amount of gum
  • the gum of (5) ie, the gum containing 10% by weight of jasmine tea extract in the total amount of gum.
  • the stickiness is considerably stronger than general gum, but in addition to increasing the blending ratio of softener, by adjusting the blending ratio of reduced maltose starch candy The stickiness is suppressed and molding is possible.
  • the gum of (6) that is, the gum containing 11% by weight of the jasmine tea extract in the total amount of the gum, is much stronger than the general gum due to the influence of the jasmine tea extract.
  • the amount of blending of the reduced maltose starch candy was reduced to some extent, but this time the entire gum became very soft and it was impossible to mold it.
  • the blending ratio of the jasmine tea extract in the total amount of gum is preferably 10% by weight or less.
  • the liquid containing jasmine tea extract shown in Table 4 is used. Based on the blend of center gum 1, (7) When the blending amount of jasmine tea extract in the gum part is 1.35% by weight (the blending amount of jasmine tea extract in the total amount of gum is 1.5% by weight) , (8) 0.85% (1.0% by weight in the total amount of gum), (9) Acetaldehyde amount in the case of 0.55% (0.7% by weight in the total amount of gum) The decrease was investigated.
  • the blend amount of erythritol was increased.
  • the test was conducted in the same manner as in Example 3. 10 mL of saliva was collected from a subject who chewed two of each of the gums (7) to (9).
  • saliva of a subject who chewed Morita's salvary gum was also collected.
  • the subsequent calculation method of the amount of acetaldehyde was in accordance with Example 3.
  • the amount of acetaldehyde in the headspace gas of the subject's saliva was 81.0.
  • the amount of acetaldehyde in the headspace gas of the subject's saliva was 84.7.
  • the amount of acetaldehyde in the headspace gas of the subject's saliva was 95.2.
  • Example 6 As a composition of the present invention, chewing gum, candy, tablet confectionery, beverage, gummy jelly, chocolate, biscuits, ice cream, sorbet, bad breath spray, toothpaste, troche, and pharmaceutical gum based on the following prescriptions Produced according to a conventional method. All of these showed a reduction effect of oral aldehyde after ingestion.
  • the jasmine tea extract in each formulation is selected from tomato powder, blueberry extract, cassis extract, EGCg high-purity product, tea extract, loaf extract, grape seed extract, assam extract, safflower extract Even in the case of changing to any one of these or a combination thereof, the effect of reducing the aldehyde in the oral cavity was also shown after taking the composition.

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Abstract

L'invention concerne une composition permettant de réduire un aldéhyde. Ladite composition permettant de réduire un aldéhyde est caractérisée en ce qu'elle contient au moins un constituant choisi parmi un extrait de thé au jasmin, une poudre de tomate, un extrait de myrtille, un extrait de cassis, un gallate d'épigallocatéchine, un extrait de Camellia sinensis O.KZE., un extrait d'écorce de Myrica rubra, un extrait de pépins de raisin, un extrait de thé Assam et un extrait de carthame.
PCT/JP2015/003713 2014-07-25 2015-07-24 Composition de réduction d'aldéhyde Ceased WO2016013228A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1020177004535A KR20170038842A (ko) 2014-07-25 2015-07-24 알데히드 저감용 조성물
CN201580041150.XA CN106573027A (zh) 2014-07-25 2015-07-24 醛减少用组合物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014152066A JP2016030723A (ja) 2014-07-25 2014-07-25 アルデヒド低減用組成物
JP2014-152066 2014-07-25

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WO2016013228A1 true WO2016013228A1 (fr) 2016-01-28
WO2016013228A9 WO2016013228A9 (fr) 2017-03-02

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4913368A (fr) * 1972-05-26 1974-02-05
JPH0930941A (ja) * 1995-07-21 1997-02-04 Pola Chem Ind Inc 口腔用組成物
JPH11123068A (ja) * 1997-10-22 1999-05-11 Toshio Imanaka 口臭防止茶
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