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WO2012148174A3 - 탈모방지 및 발모촉진용 외용제 조성물 - Google Patents

탈모방지 및 발모촉진용 외용제 조성물 Download PDF

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Publication number
WO2012148174A3
WO2012148174A3 PCT/KR2012/003200 KR2012003200W WO2012148174A3 WO 2012148174 A3 WO2012148174 A3 WO 2012148174A3 KR 2012003200 W KR2012003200 W KR 2012003200W WO 2012148174 A3 WO2012148174 A3 WO 2012148174A3
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WO
WIPO (PCT)
Prior art keywords
composition
topical application
hair growth
hair loss
stimulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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PCT/KR2012/003200
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English (en)
French (fr)
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WO2012148174A2 (ko
Inventor
박준형
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Individual
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Application filed by Individual filed Critical Individual
Priority to CN201280028162.5A priority Critical patent/CN103596550A/zh
Priority to JP2014508290A priority patent/JP5934781B2/ja
Priority to EP12776642.6A priority patent/EP2702982B1/en
Priority to US14/114,185 priority patent/US20140113887A1/en
Publication of WO2012148174A2 publication Critical patent/WO2012148174A2/ko
Publication of WO2012148174A3 publication Critical patent/WO2012148174A3/ko
Anticipated expiration legal-status Critical
Priority to US15/631,766 priority patent/US20170281506A1/en
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/10—Preparations for permanently dyeing the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/596—Mixtures of surface active compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

본 발명은 5α-리덕타아제 억제제 및 미녹시딜을 포함하는 탈모방지 및 발모촉진용 외용제 조성물에 관한 것이다. 본 발명의 탈모방지 및 발모촉진용 외용제 조성물은 종래의 경구용 5α-리덕타아제 억제제 및 미녹시딜을 각각 단독으로 또는 병합하여 사용할 때보다 훨씬 적은 양의 약물을 사용하면서도 동등 이상의 우수한 탈모방지 및 모발성장촉진 효과를 제공한다.
PCT/KR2012/003200 2011-04-25 2012-04-25 탈모방지 및 발모촉진용 외용제 조성물 Ceased WO2012148174A2 (ko)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CN201280028162.5A CN103596550A (zh) 2011-04-25 2012-04-25 用于预防脱发和促进毛发生长的局部施用的组合物
JP2014508290A JP5934781B2 (ja) 2011-04-25 2012-04-25 脱毛防止及び発毛促進用外用剤組成物
EP12776642.6A EP2702982B1 (en) 2011-04-25 2012-04-25 Composition for topical application for preventing hair loss and stimulating hair growth
US14/114,185 US20140113887A1 (en) 2011-04-25 2012-04-25 Composition for topical application for preventing hair loss and stimulating hair growth
US15/631,766 US20170281506A1 (en) 2011-04-25 2017-06-23 Composition for topical application for preventing hair loss and stimulating hair growth

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2011-0038660 2011-04-25
KR20110038660 2011-04-25
US201161515523P 2011-08-05 2011-08-05
US61/515,523 2011-08-05

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US14/114,185 A-371-Of-International US20140113887A1 (en) 2011-04-25 2012-04-25 Composition for topical application for preventing hair loss and stimulating hair growth
US15/631,766 Division US20170281506A1 (en) 2011-04-25 2017-06-23 Composition for topical application for preventing hair loss and stimulating hair growth

Publications (2)

Publication Number Publication Date
WO2012148174A2 WO2012148174A2 (ko) 2012-11-01
WO2012148174A3 true WO2012148174A3 (ko) 2013-03-28

Family

ID=47072903

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/003200 Ceased WO2012148174A2 (ko) 2011-04-25 2012-04-25 탈모방지 및 발모촉진용 외용제 조성물

Country Status (7)

Country Link
US (2) US20140113887A1 (ko)
EP (1) EP2702982B1 (ko)
JP (1) JP5934781B2 (ko)
CN (2) CN103596550A (ko)
PL (1) PL2702982T3 (ko)
PT (1) PT2702982T (ko)
WO (1) WO2012148174A2 (ko)

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CN103203021A (zh) * 2013-01-31 2013-07-17 何荫良 一种生发剂及配制方法
US20150118292A1 (en) * 2013-10-24 2015-04-30 Daniel Khesin Compositions and methods for treatment of hair loss
US10195199B2 (en) 2014-10-24 2019-02-05 Beautopia Llc Combined hair loss inhibition treatment
CN104887685A (zh) * 2015-05-05 2015-09-09 谢秉权 一种治疗和/或预防男性型脱发的复方外用药
WO2017096479A1 (en) * 2015-12-09 2017-06-15 Botaneco Inc. Personal care formulations comprising carmin protein
MY189759A (en) * 2016-03-18 2022-03-02 Caregen Co Ltd Conjugate of finasteride with peptide
EP3493785A1 (en) * 2016-08-03 2019-06-12 Rophe Pharma, Inc. Methods and compositions for promoting hair growth
CN110869020B (zh) * 2017-07-11 2023-02-03 希尔帕医疗保健有限公司 度他雄胺的局部用组合物
MX390288B (es) * 2018-02-06 2025-03-20 Centro Int De Cosmiatria S A P I De C V Formulación y método para el tratamiento de la alopecia androgénica.
TWI699209B (zh) * 2018-05-25 2020-07-21 大江生醫股份有限公司 香蕉雄蕊萃取物於製備促進毛髮生長醫藥組成物之用途
CN111110721A (zh) * 2020-01-19 2020-05-08 朱炜 一种毛发防脱再生的复合制剂及其使用方法
CN111329832B (zh) * 2020-02-08 2021-07-16 中山大学 一种治疗脱发的纳米脂质载体微针及其应用
CN111840219A (zh) * 2020-08-13 2020-10-30 黄鸿兴 一种米诺地尔与西地那非联合的生发酊剂
CN113336710A (zh) * 2021-07-08 2021-09-03 山东理工大学 一种用于治疗脱发的米诺地尔-3-甲氧基苯甲酸盐晶型及其制备方法
WO2025133909A1 (en) * 2023-12-19 2025-06-26 Glenmark Specialty S.A. Topical composition comprising dutasteride and minoxidil for alopecia
CN118384171A (zh) * 2024-04-30 2024-07-26 北京振东光明药物研究院有限公司 一种米诺地尔-度他雄胺复方外用制剂及其制备方法
CN118384170A (zh) * 2024-04-30 2024-07-26 北京振东光明药物研究院有限公司 治疗脱发的复方外用制剂及米诺地尔与度他雄胺在制备治疗脱发的外用制剂中的应用

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WO2000066072A1 (en) * 1999-05-03 2000-11-09 The Procter & Gamble Company Shampoos providing a superior combination of anti-dandruff efficacy and conditioning
KR20050119525A (ko) * 2004-06-16 2005-12-21 주식회사 태평양 엘라직산 또는 그 유도체를 함유하는 탈모 억제 또는 발모증진용 조성물
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Also Published As

Publication number Publication date
WO2012148174A2 (ko) 2012-11-01
CN103596550A (zh) 2014-02-19
PT2702982T (pt) 2017-03-17
PL2702982T3 (pl) 2017-07-31
CN106890100A (zh) 2017-06-27
JP2014516362A (ja) 2014-07-10
EP2702982A2 (en) 2014-03-05
EP2702982B1 (en) 2016-12-14
EP2702982A4 (en) 2014-11-05
US20170281506A1 (en) 2017-10-05
JP5934781B2 (ja) 2016-06-15
US20140113887A1 (en) 2014-04-24

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